WO2006078588A3 - Improved methods for treating headache - Google Patents

Improved methods for treating headache Download PDF

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Publication number
WO2006078588A3
WO2006078588A3 PCT/US2006/001432 US2006001432W WO2006078588A3 WO 2006078588 A3 WO2006078588 A3 WO 2006078588A3 US 2006001432 W US2006001432 W US 2006001432W WO 2006078588 A3 WO2006078588 A3 WO 2006078588A3
Authority
WO
WIPO (PCT)
Prior art keywords
botulinum toxin
improved methods
treating headache
headache
triptan
Prior art date
Application number
PCT/US2006/001432
Other languages
French (fr)
Other versions
WO2006078588A2 (en
Inventor
Catherine C Turkel
Mitchell F Brin
Original Assignee
Allergan Inc
Catherine C Turkel
Mitchell F Brin
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US11/039,506 external-priority patent/US20050191321A1/en
Application filed by Allergan Inc, Catherine C Turkel, Mitchell F Brin filed Critical Allergan Inc
Publication of WO2006078588A2 publication Critical patent/WO2006078588A2/en
Publication of WO2006078588A3 publication Critical patent/WO2006078588A3/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/43—Enzymes; Proenzymes; Derivatives thereof
    • A61K38/46—Hydrolases (3)
    • A61K38/48—Hydrolases (3) acting on peptide bonds (3.4)
    • A61K38/4886—Metalloendopeptidases (3.4.24), e.g. collagenase
    • A61K38/4893—Botulinum neurotoxin (3.4.24.69)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/06—Antimigraine agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/62—Medicinal preparations containing antigens or antibodies characterised by the link between antigen and carrier
    • A61K2039/627—Medicinal preparations containing antigens or antibodies characterised by the link between antigen and carrier characterised by the linker

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Neurosurgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Pain & Pain Management (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Epidemiology (AREA)
  • Immunology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Addiction (AREA)
  • Psychiatry (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

A headache can be treated more effectively by co-administration of a botulinum toxin and a triptan drug to a patient and/or the effectiveness of a triptan medication can be increased. The botulinum toxin can be botulinum toxin type A and the botulinum toxin can be administered to or to the vicinity of where a patient experiences or is predisposed to experience pain or a headache.
PCT/US2006/001432 2005-01-18 2006-01-13 Improved methods for treating headache WO2006078588A2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US11/039,506 US20050191321A1 (en) 2004-02-26 2005-01-18 Methods for treating headache
US11/039,506 2005-01-18

Publications (2)

Publication Number Publication Date
WO2006078588A2 WO2006078588A2 (en) 2006-07-27
WO2006078588A3 true WO2006078588A3 (en) 2007-01-25

Family

ID=36692768

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2006/001432 WO2006078588A2 (en) 2005-01-18 2006-01-13 Improved methods for treating headache

Country Status (1)

Country Link
WO (1) WO2006078588A2 (en)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20100266638A1 (en) * 2004-02-26 2010-10-21 Allergan, Inc. Headache treatment method
US20220016221A1 (en) * 2018-12-05 2022-01-20 Ipsen Biopharm Limited Treatment of symptoms of traumatic brain injury

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2005082339A2 (en) * 2004-02-26 2005-09-09 Allergan, Inc. Medicaments and methods for treating headache

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2005082339A2 (en) * 2004-02-26 2005-09-09 Allergan, Inc. Medicaments and methods for treating headache

Non-Patent Citations (5)

* Cited by examiner, † Cited by third party
Title
DOWSON A J ET AL: "Managing chronic headaches in the clinic.", INTERNATIONAL JOURNAL OF CLINICAL PRACTICE. DEC 2004, vol. 58, no. 12, December 2004 (2004-12-01), pages 1142 - 1151, XP002331862, ISSN: 1368-5031 *
LODER ELIZABETH ET AL: "Use of botulinum toxins for chronic headaches: a focused review.", THE CLINICAL JOURNAL OF PAIN. 2002 NOV-DEC, vol. 18, no. 6 Suppl, November 2002 (2002-11-01), pages S169 - S176, XP009048989, ISSN: 0749-8047 *
MAIZELS MORRIS: "The patient with daily headaches.", AMERICAN FAMILY PHYSICIAN. 15 DEC 2004, vol. 70, no. 12, 15 December 2004 (2004-12-15), pages 2299 - 2306, XP002331861, ISSN: 0002-838X *
SCHIM JACK: "Effect of preventive treatment with botulinum toxin type A on acute headache medication usage in migraine patients.", CURRENT MEDICAL RESEARCH AND OPINION. JAN 2004, vol. 20, no. 1, January 2004 (2004-01-01), pages 49 - 53, XP002340340, ISSN: 0300-7995 *
TEPPER STEWART ET AL: "Botulinum Toxin type A in the preventive treatment of refractory headaches: Comparison between medication overusers and nonmedication overusers groups.", CEPHALALGIA, vol. 23, no. 7, September 2003 (2003-09-01), & 11TH CONGRESS OF THE INTERNATIONAL HEADACHE SOCIETY (IHC); ROME, ITALY; SEPTEMBER 13-16, 2003, pages 715, XP009048998, ISSN: 0333-1024 *

Also Published As

Publication number Publication date
WO2006078588A2 (en) 2006-07-27

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