WO2007100590A3 - Methods for treating cellulite - Google Patents

Methods for treating cellulite Download PDF

Info

Publication number
WO2007100590A3
WO2007100590A3 PCT/US2007/004549 US2007004549W WO2007100590A3 WO 2007100590 A3 WO2007100590 A3 WO 2007100590A3 US 2007004549 W US2007004549 W US 2007004549W WO 2007100590 A3 WO2007100590 A3 WO 2007100590A3
Authority
WO
WIPO (PCT)
Prior art keywords
cellulite
methods
skin
relates
collagenase
Prior art date
Application number
PCT/US2007/004549
Other languages
French (fr)
Other versions
WO2007100590A2 (en
Inventor
Marie A Badalamente
Original Assignee
Auxilium Pharmaceuticals Inc
Marie A Badalamente
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Auxilium Pharmaceuticals Inc, Marie A Badalamente filed Critical Auxilium Pharmaceuticals Inc
Publication of WO2007100590A2 publication Critical patent/WO2007100590A2/en
Publication of WO2007100590A3 publication Critical patent/WO2007100590A3/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/43—Enzymes; Proenzymes; Derivatives thereof
    • A61K38/46—Hydrolases (3)
    • A61K38/48—Hydrolases (3) acting on peptide bonds (3.4)
    • A61K38/4886—Metalloendopeptidases (3.4.24), e.g. collagenase
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/64—Proteins; Peptides; Derivatives or degradation products thereof
    • A61K8/66—Enzymes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00—Preparations for care of the skin
    • A61Q19/06—Preparations for care of the skin for countering cellulitis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
    • A61K2800/80—Process related aspects concerning the preparation of the cosmetic composition or the storage or application thereof
    • A61K2800/91—Injection

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Medicinal Chemistry (AREA)
  • Immunology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical & Material Sciences (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Dermatology (AREA)
  • Birds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)

Abstract

The invention relates to the discovery that collagenase injections are effective in dissolving and lysing the collagenous septa network in the skin which comprises cellulite. As such, the invention relates to methods of treating cellulite in a patient in need of such treatment comprising injecting or otherwise delivering the effective amount of purified collagenase to the collagenous septa network of cellulite in the skin. The invention also relates to the use of collagenase in the manufacture of a medicament to treat cetlulite of the skin.
PCT/US2007/004549 2006-02-22 2007-02-20 Methods for treating cellulite WO2007100590A2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US77569006P 2006-02-22 2006-02-22
US60/775,690 2006-02-22

Publications (2)

Publication Number Publication Date
WO2007100590A2 WO2007100590A2 (en) 2007-09-07
WO2007100590A3 true WO2007100590A3 (en) 2008-10-09

Family

ID=38459534

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2007/004549 WO2007100590A2 (en) 2006-02-22 2007-02-20 Methods for treating cellulite

Country Status (3)

Country Link
CN (1) CN101405023A (en)
WO (1) WO2007100590A2 (en)
ZA (1) ZA200807221B (en)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK2768523T3 (en) * 2011-10-21 2019-07-22 Endo Global Ventures METHOD OF TREATMENT OR REDUCTION OF EFP
NZ766918A (en) 2012-01-12 2023-03-31 Auxilium Int Holdings Inc Clostridium histolyticum enzymes and methods for the use thereof
ES2426017B1 (en) * 2012-03-29 2014-09-17 Proteos Biotech S.L. Microemulsion comprising collagenase and uses
ES2647895T3 (en) * 2012-09-07 2017-12-27 Shiseido Company Ltd.  Method to evaluate cellulite and method to evaluate the effectiveness of a cellulite drug using fibulin-3 and / or sarcoglycan gamma as an indicator
EP3589204A1 (en) 2017-03-01 2020-01-08 Endo Ventures Limited Apparatus and method for assessing and treating cellulite
KR20240001279A (en) 2017-03-28 2024-01-03 엔도 벤쳐즈 리미티드 Improved method of producing collagenase
CA3112437A1 (en) * 2018-09-18 2020-03-26 Endo Global Aesthetics Limited Compositions and methods for treating cellulite

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4524065A (en) * 1983-08-04 1985-06-18 Bio-Specifics N.V. Method for the prevention and treatment of scars with enzymes
US4645668A (en) * 1983-08-04 1987-02-24 Biospecifics, Nv Method for the prevention and treatment of scars with enzymes
US6335388B1 (en) * 1997-10-03 2002-01-01 Lavipharm Laboratories Inc. Prolamine-plant polar lipid composition, its method of preparation and applications thereof
US6358539B1 (en) * 1999-08-20 2002-03-19 Howard Murad Pharmaceutical compositions for reducing the appearance of cellulite

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4524065A (en) * 1983-08-04 1985-06-18 Bio-Specifics N.V. Method for the prevention and treatment of scars with enzymes
US4645668A (en) * 1983-08-04 1987-02-24 Biospecifics, Nv Method for the prevention and treatment of scars with enzymes
US6335388B1 (en) * 1997-10-03 2002-01-01 Lavipharm Laboratories Inc. Prolamine-plant polar lipid composition, its method of preparation and applications thereof
US6358539B1 (en) * 1999-08-20 2002-03-19 Howard Murad Pharmaceutical compositions for reducing the appearance of cellulite

Also Published As

Publication number Publication date
WO2007100590A2 (en) 2007-09-07
ZA200807221B (en) 2009-07-29
CN101405023A (en) 2009-04-08

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