WO2006063703A8 - Polymorphisme a simple nucleotide (snp) - Google Patents

Polymorphisme a simple nucleotide (snp)

Info

Publication number
WO2006063703A8
WO2006063703A8 PCT/EP2005/012986 EP2005012986W WO2006063703A8 WO 2006063703 A8 WO2006063703 A8 WO 2006063703A8 EP 2005012986 W EP2005012986 W EP 2005012986W WO 2006063703 A8 WO2006063703 A8 WO 2006063703A8
Authority
WO
WIPO (PCT)
Prior art keywords
diabetes
type
single nucleotide
snp
nucleotide polymorphism
Prior art date
Application number
PCT/EP2005/012986
Other languages
English (en)
Other versions
WO2006063703A3 (fr
WO2006063703A2 (fr
Inventor
Malek Faham
Soren Germer
Hywel Bowden Jones
Mitchell Lee Martin
Martin Emilio Moorhead
Erik Roy Rasmussen
James Andrew Rosinski
Delphine Lagarde
Brian Kent Rhees
Original Assignee
Hoffmann La Roche
Malek Faham
Soren Germer
Hywel Bowden Jones
Mitchell Lee Martin
Martin Emilio Moorhead
Erik Roy Rasmussen
James Andrew Rosinski
Delphine Lagarde
Brian Kent Rhees
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoffmann La Roche, Malek Faham, Soren Germer, Hywel Bowden Jones, Mitchell Lee Martin, Martin Emilio Moorhead, Erik Roy Rasmussen, James Andrew Rosinski, Delphine Lagarde, Brian Kent Rhees filed Critical Hoffmann La Roche
Priority to JP2007544791A priority Critical patent/JP2008522597A/ja
Priority to EP05823148A priority patent/EP1828417A2/fr
Priority to CA002589037A priority patent/CA2589037A1/fr
Publication of WO2006063703A2 publication Critical patent/WO2006063703A2/fr
Publication of WO2006063703A3 publication Critical patent/WO2006063703A3/fr
Publication of WO2006063703A8 publication Critical patent/WO2006063703A8/fr

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6893—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids related to diseases not provided for elsewhere
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/156—Polymorphic or mutational markers
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/158—Expression markers
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/172—Haplotypes
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00—Detection or diagnosis of diseases
    • G01N2800/04—Endocrine or metabolic disorders
    • G01N2800/042—Disorders of carbohydrate metabolism, e.g. diabetes, glucose metabolism

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Hematology (AREA)
  • Immunology (AREA)
  • Diabetes (AREA)
  • Molecular Biology (AREA)
  • Analytical Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Wood Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Zoology (AREA)
  • Urology & Nephrology (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Genetics & Genomics (AREA)
  • Pathology (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Biomedical Technology (AREA)
  • Emergency Medicine (AREA)
  • Biophysics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Endocrinology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • General Physics & Mathematics (AREA)
  • Obesity (AREA)
  • Food Science & Technology (AREA)
  • Cell Biology (AREA)
  • General Engineering & Computer Science (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)

Abstract

L'invention concerne l'association du diabète de type 2 avec des polymorphismes et des haplotypes à simple nucléotide. L'invention concerne également des applications diagnostiques permettant d'identifier les patients souffrant d'un diabète de type 2 ou présentant des risques de développer un diabète de type 2 ainsi que la découverte d'agents thérapeutiques et de méthodes de traitement.
PCT/EP2005/012986 2004-12-13 2005-12-05 Polymorphisme a simple nucleotide (snp) WO2006063703A2 (fr)

Priority Applications (3)

Application Number Priority Date Filing Date Title
JP2007544791A JP2008522597A (ja) 2004-12-13 2005-12-05 Ｉｉ型糖尿病に関連する単一ヌクレオチド多型（ｓｎｐ）
EP05823148A EP1828417A2 (fr) 2004-12-13 2005-12-05 Polymorphisme a simple nucleotide (snp) associes au diabete sucre de type 2
CA002589037A CA2589037A1 (fr) 2004-12-13 2005-12-05 Polymorphisme a simple nucleotide (snp)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US63556304P 2004-12-13 2004-12-13
US60/635,563 2004-12-13
US71432105P 2005-09-06 2005-09-06
US60/714,321 2005-09-06

Publications (3)

Publication Number Publication Date
WO2006063703A2 WO2006063703A2 (fr) 2006-06-22
WO2006063703A3 WO2006063703A3 (fr) 2006-10-26
WO2006063703A8 true WO2006063703A8 (fr) 2007-11-08

Family

ID=35799724

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/EP2005/012986 WO2006063703A2 (fr) 2004-12-13 2005-12-05 Polymorphisme a simple nucleotide (snp)

Country Status (4)

Country Link
EP (1) EP1828417A2 (fr)
JP (1) JP2008522597A (fr)
CA (1) CA2589037A1 (fr)
WO (1) WO2006063703A2 (fr)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2102368A1 (fr) * 2007-01-19 2009-09-23 Integragen Gène btbd9 de susceptibilité au diabète humain
US20110129820A1 (en) * 2007-04-10 2011-06-02 Integragen Human diabetes susceptibility tnfrsf10b gene
WO2008122673A2 (fr) * 2007-04-10 2008-10-16 Integragen Gène tnfrsf10a de susceptibilité au diabète chez l'homme
EP2134867A1 (fr) * 2007-04-10 2009-12-23 Integragen Gène tnfrsf10c de susceptibilité au diabète chez l'homme
WO2008122672A1 (fr) * 2007-04-10 2008-10-16 Integragen Gène tnfrsf10d de susceptibilité au diabète chez l'homme
EP2145020A2 (fr) * 2007-05-04 2010-01-20 Integragen Gène eefsec humain de prédisposition au diabète
CN103882127B (zh) * 2014-03-13 2016-03-16 河北联合大学 用于预测患2型糖尿病肾病发生风险的试剂盒

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5863724A (en) * 1994-04-13 1999-01-26 Baylor College Of Medicine Methods of screening for persistent hyperinsulinemic hypoglycemia of infancy
US6783942B2 (en) * 1998-10-08 2004-08-31 Uab Research Foundation Isolated polynucleotide associated with type II diabetes mellitus and methods of use thereof
EP1348031A2 (fr) * 2000-12-27 2003-10-01 Riken Detection de polymorphismes genetiques dans des genes associes avec pharmacogenomiques
WO2004084797A2 (fr) * 2003-02-28 2004-10-07 Hubit Genomix Inc Gene associe au diabete sucre du type 2 et son utilisation

Also Published As

Publication number Publication date
JP2008522597A (ja) 2008-07-03
EP1828417A2 (fr) 2007-09-05
WO2006063703A3 (fr) 2006-10-26
WO2006063703A2 (fr) 2006-06-22
CA2589037A1 (fr) 2006-06-22

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