WO2006057893A3 - Composition, delivery system and method for promoting healthy sexual function - Google Patents

Composition, delivery system and method for promoting healthy sexual function Download PDF

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Publication number
WO2006057893A3
WO2006057893A3 PCT/US2005/041765 US2005041765W WO2006057893A3 WO 2006057893 A3 WO2006057893 A3 WO 2006057893A3 US 2005041765 W US2005041765 W US 2005041765W WO 2006057893 A3 WO2006057893 A3 WO 2006057893A3
Authority
WO
WIPO (PCT)
Prior art keywords
carnitine
compositions
sexual function
extract
promoting healthy
Prior art date
Application number
PCT/US2005/041765
Other languages
French (fr)
Other versions
WO2006057893A2 (en
Inventor
Edward Larry Mccleary
Carl A Forest
Christine Mccleary
Original Assignee
Edward Larry Mccleary
Carl A Forest
Christine Mccleary
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US11/049,244 external-priority patent/US20060110478A1/en
Priority claimed from US11/049,237 external-priority patent/US20060110477A1/en
Application filed by Edward Larry Mccleary, Carl A Forest, Christine Mccleary filed Critical Edward Larry Mccleary
Publication of WO2006057893A2 publication Critical patent/WO2006057893A2/en
Publication of WO2006057893A3 publication Critical patent/WO2006057893A3/en

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Classifications

    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23G—COCOA; COCOA PRODUCTS, e.g. CHOCOLATE; SUBSTITUTES FOR COCOA OR COCOA PRODUCTS; CONFECTIONERY; CHEWING GUM; ICE-CREAM; PREPARATION THEREOF
    • A23G1/00—Cocoa; Cocoa products, e.g. chocolate; Substitutes therefor
    • A23G1/30—Cocoa products, e.g. chocolate; Substitutes therefor
    • A23G1/32—Cocoa products, e.g. chocolate; Substitutes therefor characterised by the composition containing organic or inorganic compounds
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23G—COCOA; COCOA PRODUCTS, e.g. CHOCOLATE; SUBSTITUTES FOR COCOA OR COCOA PRODUCTS; CONFECTIONERY; CHEWING GUM; ICE-CREAM; PREPARATION THEREOF
    • A23G3/00—Sweetmeats; Confectionery; Marzipan; Coated or filled products
    • A23G3/34—Sweetmeats, confectionery or marzipan; Processes for the preparation thereof
    • A23G3/36—Sweetmeats, confectionery or marzipan; Processes for the preparation thereof characterised by the composition containing organic or inorganic compounds
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L27/00—Spices; Flavouring agents or condiments; Artificial sweetening agents; Table salts; Dietetic salt substitutes; Preparation or treatment thereof
    • A23L27/60—Salad dressings; Mayonnaise; Ketchup
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
    • A23L33/105—Plant extracts, their artificial duplicates or their derivatives
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
    • A23L33/17—Amino acids, peptides or proteins
    • A23L33/175—Amino acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/48—Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
    • A61K36/489—Sophora, e.g. necklacepod or mamani
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/85—Verbenaceae (Verbena family)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Natural Medicines & Medicinal Plants (AREA)
  • Engineering & Computer Science (AREA)
  • Food Science & Technology (AREA)
  • Polymers & Plastics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Mycology (AREA)
  • General Health & Medical Sciences (AREA)
  • Epidemiology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Nutrition Science (AREA)
  • Botany (AREA)
  • Microbiology (AREA)
  • Medical Informatics (AREA)
  • Biotechnology (AREA)
  • Alternative & Traditional Medicine (AREA)
  • Inorganic Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines Containing Plant Substances (AREA)

Abstract

Improved compositions, delivery systems and methods for promoting healthy sexual function. The compositions include a portion or extract of the plant Sophora flavescens, such as sophoflavescenol. The compositions also include Vitex agnus-castus extract, and/or one or more of lipoic acid, L-Arginine, folic acid, trimethylglycine, policosanol, carnitine, biotin, and acetyl L-Carnitine and anti-oxidants. A composition including one or more cGMP-specific PDE5 inhibitors and/or dopaminergic agonists is administered in the form of a breath-care strip, mint or lozenge, or a food or beverage product. The cGMP-specific PDE5 inhibitor comprises an ingredient selected from the group consisting of sophoflavescenol, vardenafil, tadalafil, and sildenafil. The dopaminergic agonist comprises apomorphine. Vitex agnus-castus extract, and/or one or more of lipoic acid, L-Arginine, folic acid, trimethylglycine, policosanol, carnitine, biotin, and acetyl L-Carnitine may also be included in the delivery vehicle.
PCT/US2005/041765 2004-11-22 2005-11-17 Composition, delivery system and method for promoting healthy sexual function WO2006057893A2 (en)

Applications Claiming Priority (6)

Application Number Priority Date Filing Date Title
US63052904P 2004-11-22 2004-11-22
US60/630,529 2004-11-22
US11/049,244 2005-02-02
US11/049,244 US20060110478A1 (en) 2004-11-22 2005-02-02 Delivery system and method for supporting and promoting healthy sexual function and prevention and treatment of sexual dysfunction
US11/049,237 2005-02-02
US11/049,237 US20060110477A1 (en) 2004-11-22 2005-02-02 Composition and method for supporting and promoting healthy sexual function and prevention and treatment of sexual dysfunction

Publications (2)

Publication Number Publication Date
WO2006057893A2 WO2006057893A2 (en) 2006-06-01
WO2006057893A3 true WO2006057893A3 (en) 2006-08-24

Family

ID=35976463

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2005/041765 WO2006057893A2 (en) 2004-11-22 2005-11-17 Composition, delivery system and method for promoting healthy sexual function

Country Status (1)

Country Link
WO (1) WO2006057893A2 (en)

Citations (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1992016217A1 (en) * 1989-09-22 1992-10-01 Walter Weil Sexual tonic for men
CN1285197A (en) * 2000-08-17 2001-02-28 谭恭娇 Paint liquid medicine for skin recovery of burn and scald and preparation process thereof
WO2002000237A1 (en) * 2000-06-29 2002-01-03 Dr. Willmar Schwabe Gmbh & Co. Therapeutical use of sophora flavescens or sophora subprostrata extracts
JP2002029935A (en) * 2000-07-17 2002-01-29 Taisho Pharmaceut Co Ltd Hair-growing agent
US20020122834A1 (en) * 2000-12-22 2002-09-05 Trant Aileen Sontag Method and composition for improving fertility health in female and male animals and humans
WO2002074321A1 (en) * 2001-03-21 2002-09-26 N.V. Nutricia Composition comprising cocoa and a dopamine d2 receptor agonist
KR20030088906A (en) * 2002-05-15 2003-11-21 한국과학기술연구원 A composition for treating sexual dysfunction comprising an extract from sophora flavescenes and compounds isolated therefrom

Patent Citations (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1992016217A1 (en) * 1989-09-22 1992-10-01 Walter Weil Sexual tonic for men
WO2002000237A1 (en) * 2000-06-29 2002-01-03 Dr. Willmar Schwabe Gmbh & Co. Therapeutical use of sophora flavescens or sophora subprostrata extracts
JP2002029935A (en) * 2000-07-17 2002-01-29 Taisho Pharmaceut Co Ltd Hair-growing agent
CN1285197A (en) * 2000-08-17 2001-02-28 谭恭娇 Paint liquid medicine for skin recovery of burn and scald and preparation process thereof
US20020122834A1 (en) * 2000-12-22 2002-09-05 Trant Aileen Sontag Method and composition for improving fertility health in female and male animals and humans
WO2002074321A1 (en) * 2001-03-21 2002-09-26 N.V. Nutricia Composition comprising cocoa and a dopamine d2 receptor agonist
KR20030088906A (en) * 2002-05-15 2003-11-21 한국과학기술연구원 A composition for treating sexual dysfunction comprising an extract from sophora flavescenes and compounds isolated therefrom

Non-Patent Citations (6)

* Cited by examiner, † Cited by third party
Title
DATABASE WPI Section Ch Week 200134, Derwent World Patents Index; Class B04, AN 2001-317506, XP002385847 *
DATABASE WPI Section Ch Week 200236, Derwent World Patents Index; Class B03, AN 2002-322824, XP002385848 *
DATABASE WPI Section Ch Week 200422, Derwent World Patents Index; Class B04, AN 2004-235747, XP002385846 *
ODENTHAL K P: "Vitex agnus castus L., - Traditional drug and actual indications", 1998, PHYTOTHERAPY RESEARCH 1998 UNITED KINGDOM, VOL. 12, NR. SUPPL. 1, PAGE(S) S160-S161, ISSN: 0951-418X, XP009063360 *
SHIN HYE JOO ET AL: "A prenylated flavonol, sophoflavescenol: A potent and selective inhibitor of cGMP phosphodiesterase 5", BIOORGANIC AND MEDICINAL CHEMISTRY LETTERS, vol. 12, no. 17, September 2002 (2002-09-01), pages 2313 - 2316, XP009067851, ISSN: 0960-894X *
ZWAVING J H ET AL: "Composition of the essential fruit oil of Vitex agnus-castus", 1996, PLANTA MEDICA, VOL. 62, NR. 1, PAGE(S) 83-84, ISSN: 0032-0943, XP009063362 *

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Publication number Publication date
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