WO2006055437A3 - Synthesis and use of glycodendrimer reagents - Google Patents

Synthesis and use of glycodendrimer reagents Download PDF

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Publication number
WO2006055437A3
WO2006055437A3 PCT/US2005/040989 US2005040989W WO2006055437A3 WO 2006055437 A3 WO2006055437 A3 WO 2006055437A3 US 2005040989 W US2005040989 W US 2005040989W WO 2006055437 A3 WO2006055437 A3 WO 2006055437A3
Authority
WO
WIPO (PCT)
Prior art keywords
synthesis
glycodendrimer
reagents
glycodendrimer reagents
disaccharides
Prior art date
Application number
PCT/US2005/040989
Other languages
French (fr)
Other versions
WO2006055437A2 (en
Inventor
Richard R Bott
Benjamin G Davis
John Bryan Jones
Original Assignee
Genencor Int
Isis Innovation
Univ Toronto
Richard R Bott
Benjamin G Davis
John Bryan Jones
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Genencor Int, Isis Innovation, Univ Toronto, Richard R Bott, Benjamin G Davis, John Bryan Jones filed Critical Genencor Int
Publication of WO2006055437A2 publication Critical patent/WO2006055437A2/en
Publication of WO2006055437A3 publication Critical patent/WO2006055437A3/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
    • C08G83/00—Macromolecular compounds not provided for in groups C08G2/00 - C08G81/00
    • C08G83/002—Dendritic macromolecules
    • C08G83/003—Dendrimers
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H1/00—Processes for the preparation of sugar derivatives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/02—Acyclic radicals, not substituted by cyclic structures
    • C07H15/14—Acyclic radicals, not substituted by cyclic structures attached to a sulfur, selenium or tellurium atom of a saccharide radical

Abstract

The present invention relates to synthetic methods for producing glycodendrimer reagents from disaccharides having a sulhydryl group
PCT/US2005/040989 2004-11-16 2005-11-14 Synthesis and use of glycodendrimer reagents WO2006055437A2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US62882904P 2004-11-16 2004-11-16
US60/628,829 2004-11-16

Publications (2)

Publication Number Publication Date
WO2006055437A2 WO2006055437A2 (en) 2006-05-26
WO2006055437A3 true WO2006055437A3 (en) 2006-07-13

Family

ID=36120100

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2005/040989 WO2006055437A2 (en) 2004-11-16 2005-11-14 Synthesis and use of glycodendrimer reagents

Country Status (1)

Country Link
WO (1) WO2006055437A2 (en)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP5591855B2 (en) 2012-03-22 2014-09-17 富士フイルム株式会社 Polymerizable compound precursor

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2002079394A2 (en) * 2001-04-02 2002-10-10 Genencor International, Inc. Synthesis and use of glycodendrimer reagents

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2002079394A2 (en) * 2001-04-02 2002-10-10 Genencor International, Inc. Synthesis and use of glycodendrimer reagents

Non-Patent Citations (7)

* Cited by examiner, † Cited by third party
Title
KALOVIDOURIS S A ET AL: "Chemically Defined Sialoside Scaffolds for Investigation of Multivalent Interactions with Sialic Acid Binding Proteins", JOURNAL OF ORGANIC CHEMISTRY 31 OCT 2003 UNITED STATES, vol. 68, no. 22, 31 October 2003 (2003-10-31), pages 8485 - 8493, XP002376809, ISSN: 0022-3263 *
MENG X-B ET AL: "Facile synthesis of 1-thio-beta-lactoside clusters scaffolded onto p-methoxyphenyl, beta-d-galactopyranoside, beta-d-glucopyranoside, and lactoside", CARBOHYDRATE RESEARCH, ELSEVIER SCIENTIFIC PUBLISHING COMPANY. AMSTERDAM, NL, vol. 337, no. 11, 5 June 2002 (2002-06-05), pages 977 - 981, XP004367084, ISSN: 0008-6215 *
NELSON A ET AL: "Synthesis of lactoside glycodendrons using photoaddition and reductive amination methodologies", CARBOHYDRATE RESEARCH, ELSEVIER SCIENTIFIC PUBLISHING COMPANY. AMSTERDAM, NL, vol. 339, no. 12, 23 August 2004 (2004-08-23), pages 2069 - 2075, XP004522914, ISSN: 0008-6215 *
ROY RENÉ ET AL: "Glycodendrimers: novel glycotope isosteres unmasking sugar coding. case study with T-antigen markers from breast cancer MUC1 glycoprotein.", REVIEWS IN MOLECULAR BIOTECHNOLOGY, ELSEVIER, AMSTERDAM,, NL, vol. 90, no. 3-4, May 2002 (2002-05-01), pages 291 - 309, XP002376806, ISSN: 1389-0352 *
THOMA GEBHARD ET AL: "Novel glycodendrimers self-assemble to nanoparticles which function as polyvalent ligands in vitro and in vivo.", ANGEWANDTE CHEMIE (INTERNATIONAL ED. IN ENGLISH) 2 SEP 2002, vol. 41, no. 17, 2 September 2002 (2002-09-02), pages 3195 - 3198, XP002376807, ISSN: 0570-0833 *
VARGAS-BERENGUEL ANTONIO ET AL: "Dendritic galactosides based on a beta-cyclodextrin core for the construction of site-specific molecular delivery systems: synthesis and molecular recognition studies.", CHEMISTRY (WEINHEIM AN DER BERGSTRASSE, GERMANY) 15 FEB 2002, vol. 8, no. 4, 15 February 2002 (2002-02-15), pages 812 - 827, XP002376808, ISSN: 0947-6539 *
ZANINI D ET AL: "Synthesis of novel dendritic glycosides", TETRAHEDRON LETTERS, ELSEVIER, AMSTERDAM, NL, vol. 36, no. 41, 9 October 1995 (1995-10-09), pages 7383 - 7386, XP004295876, ISSN: 0040-4039 *

Also Published As

Publication number Publication date
WO2006055437A2 (en) 2006-05-26

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