WO2006051241A3 - Procede de couplage de molecules non immunogenes, compose intermediaire, produit final obtenu et utilisations - Google Patents
Procede de couplage de molecules non immunogenes, compose intermediaire, produit final obtenu et utilisations Download PDFInfo
- Publication number
- WO2006051241A3 WO2006051241A3 PCT/FR2005/050942 FR2005050942W WO2006051241A3 WO 2006051241 A3 WO2006051241 A3 WO 2006051241A3 FR 2005050942 W FR2005050942 W FR 2005050942W WO 2006051241 A3 WO2006051241 A3 WO 2006051241A3
- Authority
- WO
- WIPO (PCT)
- Prior art keywords
- intermediate compound
- final product
- product obtained
- immunogenic molecules
- coupling non
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
- A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
- A61K47/62—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being a protein, peptide or polyamino acid
- A61K47/64—Drug-peptide, drug-protein or drug-polyamino acid conjugates, i.e. the modifying agent being a peptide, protein or polyamino acid which is covalently bonded or complexed to a therapeutically active agent
- A61K47/646—Drug-peptide, drug-protein or drug-polyamino acid conjugates, i.e. the modifying agent being a peptide, protein or polyamino acid which is covalently bonded or complexed to a therapeutically active agent the entire peptide or protein drug conjugate elicits an immune response, e.g. conjugate vaccines
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Molecular Biology (AREA)
- Chemical & Material Sciences (AREA)
- Virology (AREA)
- Immunology (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Peptides Or Proteins (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Abstract
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
FR0452591 | 2004-11-10 | ||
FR0452591A FR2877668B1 (fr) | 2004-11-10 | 2004-11-10 | Procede de couplage de molecules non immunogenes, compose intermediaire, produit final obtenu et utilisations |
Publications (2)
Publication Number | Publication Date |
---|---|
WO2006051241A2 WO2006051241A2 (fr) | 2006-05-18 |
WO2006051241A3 true WO2006051241A3 (fr) | 2006-11-09 |
Family
ID=34954138
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PCT/FR2005/050942 WO2006051241A2 (fr) | 2004-11-10 | 2005-11-10 | Procede de couplage de molecules non immunogenes, compose intermediaire, produit final obtenu et utilisations |
Country Status (2)
Country | Link |
---|---|
FR (1) | FR2877668B1 (fr) |
WO (1) | WO2006051241A2 (fr) |
Families Citing this family (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN102008732B (zh) * | 2010-11-08 | 2012-10-24 | 武汉华耀生物医药有限公司 | 一种叶酸偶联抗体药物及其制备方法与应用 |
US20190343951A1 (en) * | 2017-01-13 | 2019-11-14 | National Research Council Of Canada | Method of optimizing peptide immuno-epitope by glycosylation, optimized peptide thereof and its use for conjugate vaccines |
Citations (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5876727A (en) * | 1995-03-31 | 1999-03-02 | Immulogic Pharmaceutical Corporation | Hapten-carrier conjugates for use in drug-abuse therapy and methods for preparation of same |
US20030077287A1 (en) * | 1997-09-19 | 2003-04-24 | Serex, Inc. | Methods to improve immunogenicity of antigens and specificity of antibodies |
-
2004
- 2004-11-10 FR FR0452591A patent/FR2877668B1/fr not_active Expired - Fee Related
-
2005
- 2005-11-10 WO PCT/FR2005/050942 patent/WO2006051241A2/fr active Application Filing
Patent Citations (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5876727A (en) * | 1995-03-31 | 1999-03-02 | Immulogic Pharmaceutical Corporation | Hapten-carrier conjugates for use in drug-abuse therapy and methods for preparation of same |
US20030077287A1 (en) * | 1997-09-19 | 2003-04-24 | Serex, Inc. | Methods to improve immunogenicity of antigens and specificity of antibodies |
Non-Patent Citations (8)
Title |
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CONCHILLO A ET AL: "3 4 EPOXYPRECOCENES AS MODELS OF CYTOTOXIC EPOXIDES SYNTHESIS OF THE CIS ADDUCTS OCCURRING IN THE GLUTATHIONE METABOLIC PATHWAY", JOURNAL OF ORGANIC CHEMISTRY, vol. 55, no. 6, 1990, pages 1728 - 1735, XP002375121, ISSN: 0022-3263 * |
GLUSHKOV A N ET AL: "Antisera to polycyclic aromatic hydrocarbons and their application on the detection of chemical carcinogens in blood sera of oncological patients", EXPERIMENTAL ONCOLOGY 2004 UKRAINE, vol. 26, no. 2, June 2004 (2004-06-01), pages 145 - 148, XP002375119, ISSN: 0204-3564 * |
LEE JAE KOO ET AL: "Development of an immunoassay for the residues of the herbicide bensulfuron-methyl", JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY, vol. 50, no. 7, 27 March 2002 (2002-03-27), pages 1791 - 1803, XP002374931, ISSN: 0021-8561 * |
LI KAI ET AL: "Development of an enzyme-linked immunosorbent assay for the insecticide imidacloprid", JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY, vol. 48, no. 8, August 2000 (2000-08-01), pages 3378 - 3382, XP002374930, ISSN: 0021-8561 * |
MARCO MARIA-PILAR ET AL: "Hapten design and development of an ELISA (enzyme-linked immunosorbent assay) for the detection of the mercapturic acid conjugates of naphthalene", JOURNAL OF ORGANIC CHEMISTRY, vol. 58, no. 26, 1993, pages 7548 - 7556, XP002374932, ISSN: 0022-3263 * |
MARCO M-P ET AL: "Enzyme-linked immunosorbent assay for the specific detection of the mercapturic acid metabolites of naphthalene", CHEMICAL RESEARCH IN TOXICOLOGY 1993 UNITED STATES, vol. 6, no. 3, 1993, pages 284 - 293, XP002374933, ISSN: 0893-228X * |
MURTY V S ET AL: "Characterization of mercapturic acid and glutathionyl conjugates of benzo[a]pyrene-7,8-dione by two-dimensional NMR.", BIOCONJUGATE CHEMISTRY. 1992 MAY-JUN, vol. 3, no. 3, May 1992 (1992-05-01), pages 218 - 224, XP002375120, ISSN: 1043-1802 * |
YANG Y ET AL: "Liquid chromatography-mass spectrometry with collision-induced dissociation of conjugated metabolites of benzo[a]pyrene", JOURNAL OF THE AMERICAN SOCIETY FOR MASS SPECTROMETRY 1997 UNITED STATES, vol. 8, no. 1, 1997, pages 50 - 61, XP005271113, ISSN: 1044-0305 * |
Also Published As
Publication number | Publication date |
---|---|
FR2877668A1 (fr) | 2006-05-12 |
FR2877668B1 (fr) | 2007-07-06 |
WO2006051241A2 (fr) | 2006-05-18 |
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