WO2006050451A3 - Methodes et compositions pour traiter des maladies des motoneurones - Google Patents

Methodes et compositions pour traiter des maladies des motoneurones Download PDF

Info

Publication number
WO2006050451A3
WO2006050451A3 PCT/US2005/039710 US2005039710W WO2006050451A3 WO 2006050451 A3 WO2006050451 A3 WO 2006050451A3 US 2005039710 W US2005039710 W US 2005039710W WO 2006050451 A3 WO2006050451 A3 WO 2006050451A3
Authority
WO
WIPO (PCT)
Prior art keywords
compositions
methods
motor neuron
neuron disease
treat motor
Prior art date
Application number
PCT/US2005/039710
Other languages
English (en)
Other versions
WO2006050451A2 (fr
Inventor
Brent R Stockwell
Original Assignee
Whitehead Biomedical Inst
Univ Columbia
Brent R Stockwell
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Whitehead Biomedical Inst, Univ Columbia, Brent R Stockwell filed Critical Whitehead Biomedical Inst
Publication of WO2006050451A2 publication Critical patent/WO2006050451A2/fr
Publication of WO2006050451A3 publication Critical patent/WO2006050451A3/fr

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D209/00Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/44Iso-indoles; Hydrogenated iso-indoles
    • C07D209/46Iso-indoles; Hydrogenated iso-indoles with an oxygen atom in position 1

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

L'invention concerne des compositions et des méthodes pour traiter des maladies des motoneurones, telles que l'amyotrophie spinale et la sclérose latérale amyotrophique. Ces compositions contiennent des dérivés d'indoprofène.
PCT/US2005/039710 2004-11-02 2005-11-02 Methodes et compositions pour traiter des maladies des motoneurones WO2006050451A2 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US62422604P 2004-11-02 2004-11-02
US60/624,226 2004-11-02

Publications (2)

Publication Number Publication Date
WO2006050451A2 WO2006050451A2 (fr) 2006-05-11
WO2006050451A3 true WO2006050451A3 (fr) 2006-09-28

Family

ID=36319807

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2005/039710 WO2006050451A2 (fr) 2004-11-02 2005-11-02 Methodes et compositions pour traiter des maladies des motoneurones

Country Status (1)

Country Link
WO (1) WO2006050451A2 (fr)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8110681B2 (en) 2006-03-17 2012-02-07 The United States Of America As Represented By The Secretary, Department Of Health And Human Services Compounds for the treatment of spinal muscular atrophy and other uses
EP2573080A1 (fr) * 2007-09-27 2013-03-27 The United States of America, as Represented by the Secretary, Department of Health and Human Services Composés d'Isoindoline pour le traitement d'une amyotrophie spinale et autres utilisations
EP2872493B1 (fr) * 2012-07-13 2018-11-14 Indiana University Research and Technology Corporation 5,6,7-trimethoxy 4-phenyle quinoline-2-ones utilisables en vue du traitement de l'amyotrophie spinale
KR102560706B1 (ko) 2015-10-01 2023-07-27 삼성전자주식회사 인도프로펜을 포함하는 조성물 및 그의 용도
JP6671664B2 (ja) * 2016-05-24 2020-03-25 学校法人東京女子医科大学 Smnタンパク質の核内構造体の発現解析方法
EP3801468A4 (fr) * 2018-05-25 2022-03-09 Revalesio Corporation Inhibition de maladie neurologique

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3997669A (en) * 1972-12-26 1976-12-14 Ciba-Geigy Corporation Tertiary aminoacids
US4126691A (en) * 1968-03-27 1978-11-21 Ciba-Geigy Corporation Tertiary aminoacids

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4126691A (en) * 1968-03-27 1978-11-21 Ciba-Geigy Corporation Tertiary aminoacids
US3997669A (en) * 1972-12-26 1976-12-14 Ciba-Geigy Corporation Tertiary aminoacids

Also Published As

Publication number Publication date
WO2006050451A2 (fr) 2006-05-11

Similar Documents

Publication Publication Date Title
MX2023006169A (es) Terapia genica para trastornos neurodegenerativos.
WO2007022470A3 (fr) Methodes et compositions pour le traitement de maladies neurologiques
WO2008021210A3 (fr) Méthodes et compositions pour le traitement de troubles neurodégénératifs
WO2006083533A3 (fr) Compositions et methodes d'inhibition de la formation de drusen et methodes de diagnostic ou de traitement de pathologies liees aux drusen
WO2005086656A3 (fr) Derives d'heteroarylaminopyrazole utilises pour traiter le diabete
WO2004100881A3 (fr) Preparation et utilisation de derives d'aryl alkyl acide pour le traitement de l'obesite
WO2006116609A3 (fr) Procedes permettant de traiter les maladies des neurones moteurs peripheriques et compositions associees
WO2004062625A3 (fr) Inhibiteurs de beta-secretase macrocyclique pour traiter la maladie d'alzheimer
WO2006001877A3 (fr) Composition pharmaceutique et methode de traitement de troubles neurodegeneratifs
WO2005004803A3 (fr) Inhibiteurs de la beta-secretase de phenylcarboxylate destines au traitement de la maladie d'alzheimer
WO2007092622A3 (fr) Compositions et méthodes pour le traitement d'os
WO2006121560A3 (fr) Procedes et compositions pour le traitement des pathologies associees au systeme nerveux central
WO2007016538A3 (fr) Preparation et utilisation de derives aminoacides biphenyle pour traiter l'obesite
WO2006113864A3 (fr) Composes d'oxindole et leurs utilisations comme agents therapeutiques
WO2010048273A3 (fr) Procédés et composés pour le traitement de troubles neurodégénératifs
WO2007064932A3 (fr) Dérivés de pyrrolotriazine utiles pour traiter le cancer par inhibition de la kinase aurora
WO2006058868A3 (fr) Pteridines substituees destinees au traitement de maladies inflammatoires
WO2007137071A3 (fr) Compositions de r(+) et s(-) pramipéxole et procédés d'utilisation de celles-ci
WO2005018545A3 (fr) Inhibiteurs macrocycliques de la beta-secretase destines au traitement de la maladie d'alzheimer
WO2006057945A3 (fr) Derives pyridyle 2,3,4,6-substitues utiles comme inhibiteurs de la beta-secretase pour le traitement de la maladie d'alzheimer
WO2005051914A8 (fr) Inhibiteurs de benzylether et benzylamino de beta-secretase pour traiter la maladie d'alzheimer
WO2006078576A3 (fr) Inhibiteurs de la $g(b)-secretase d'aminomethyle dans le traitement de la maladie d'alzheimer
TW200628473A (en) Novel heterocycles
WO2010075280A3 (fr) Composés à base de coumarine
WO2006050451A3 (fr) Methodes et compositions pour traiter des maladies des motoneurones

Legal Events

Date Code Title Description
AK Designated states

Kind code of ref document: A2

Designated state(s): AE AG AL AM AT AU AZ BA BB BG BR BW BY BZ CA CH CN CO CR CU CZ DE DK DM DZ EC EE EG ES FI GB GD GE GH GM HR HU ID IL IN IS JP KE KG KM KN KP KR KZ LC LK LR LS LT LU LV LY MA MD MG MK MN MW MX MZ NA NG NI NO NZ OM PG PH PL PT RO RU SC SD SE SG SK SL SM SY TJ TM TN TR TT TZ UA UG US UZ VC VN YU ZA ZM ZW

AL Designated countries for regional patents

Kind code of ref document: A2

Designated state(s): BW GH GM KE LS MW MZ NA SD SL SZ TZ UG ZM ZW AM AZ BY KG KZ MD RU TJ TM AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IS IT LT LU LV MC NL PL PT RO SE SI SK TR BF BJ CF CG CI CM GA GN GQ GW ML MR NE SN TD TG

121 Ep: the epo has been informed by wipo that ep was designated in this application
NENP Non-entry into the national phase

Ref country code: DE

122 Ep: pct application non-entry in european phase

Ref document number: 05848830

Country of ref document: EP

Kind code of ref document: A2