WO2006046130A3 - Process for the preparation of pravastatin - Google Patents

Process for the preparation of pravastatin Download PDF

Info

Publication number
WO2006046130A3
WO2006046130A3 PCT/IB2005/003270 IB2005003270W WO2006046130A3 WO 2006046130 A3 WO2006046130 A3 WO 2006046130A3 IB 2005003270 W IB2005003270 W IB 2005003270W WO 2006046130 A3 WO2006046130 A3 WO 2006046130A3
Authority
WO
WIPO (PCT)
Prior art keywords
preparation
pravastatin
relates
pure pravastatin
compositions
Prior art date
Application number
PCT/IB2005/003270
Other languages
French (fr)
Other versions
WO2006046130A2 (en
Inventor
Parveen Kumar
Manish Mandlecha
Ashoke Mitra
Original Assignee
Ranbaxy Lab Ltd
Parveen Kumar
Manish Mandlecha
Ashoke Mitra
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ranbaxy Lab Ltd, Parveen Kumar, Manish Mandlecha, Ashoke Mitra filed Critical Ranbaxy Lab Ltd
Publication of WO2006046130A2 publication Critical patent/WO2006046130A2/en
Publication of WO2006046130A3 publication Critical patent/WO2006046130A3/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C67/00—Preparation of carboxylic acid esters
    • C07C67/48—Separation; Purification; Stabilisation; Use of additives
    • C07C67/56—Separation; Purification; Stabilisation; Use of additives by solid-liquid treatment; by chemisorption

Abstract

The invention relates to a process for the preparation of pure pravastatin or a salt thereof using adsorption matrices. The invention also relates to pharmaceutical compositions that include the pure pravastatin and the use of the compositions for treating hypercholesterolemia.
PCT/IB2005/003270 2004-10-29 2005-10-31 Process for the preparation of pravastatin WO2006046130A2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IN2171/DEL/2004 2004-10-29
IN2171DE2004 2004-10-29

Publications (2)

Publication Number Publication Date
WO2006046130A2 WO2006046130A2 (en) 2006-05-04
WO2006046130A3 true WO2006046130A3 (en) 2006-07-13

Family

ID=35744743

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/IB2005/003270 WO2006046130A2 (en) 2004-10-29 2005-10-31 Process for the preparation of pravastatin

Country Status (1)

Country Link
WO (1) WO2006046130A2 (en)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN109796333B (en) * 2019-01-25 2021-04-09 北大方正集团有限公司 Method for extracting and purifying pravastatin sodium from fermentation liquor

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5272174A (en) * 1985-09-13 1993-12-21 Sankyo Company, Limited Hydroxy-ML-236B derivatives, their preparation and use
US20020081675A1 (en) * 1999-02-03 2002-06-27 Antonia Jekkel Microbial process for preparing pravastatin
US20020187531A1 (en) * 1999-11-30 2002-12-12 Vilmos Keri Process for recovering statin compounds from a fermentation broth

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5272174A (en) * 1985-09-13 1993-12-21 Sankyo Company, Limited Hydroxy-ML-236B derivatives, their preparation and use
US20020081675A1 (en) * 1999-02-03 2002-06-27 Antonia Jekkel Microbial process for preparing pravastatin
US20020187531A1 (en) * 1999-11-30 2002-12-12 Vilmos Keri Process for recovering statin compounds from a fermentation broth

Also Published As

Publication number Publication date
WO2006046130A2 (en) 2006-05-04

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