WO2006038007A3 - Inhibitory analogues to block receptors for microbial pathogenic determinants - Google Patents
Inhibitory analogues to block receptors for microbial pathogenic determinants Download PDFInfo
- Publication number
- WO2006038007A3 WO2006038007A3 PCT/GB2005/003836 GB2005003836W WO2006038007A3 WO 2006038007 A3 WO2006038007 A3 WO 2006038007A3 GB 2005003836 W GB2005003836 W GB 2005003836W WO 2006038007 A3 WO2006038007 A3 WO 2006038007A3
- Authority
- WO
- WIPO (PCT)
- Prior art keywords
- microbial pathogenic
- inhibitory analogues
- block receptors
- pathogenic determinants
- determinants
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/164—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
- C07K14/33—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Clostridium (G)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
Abstract
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB0708711A GB2434580A (en) | 2004-10-05 | 2007-05-04 | Inhibitory analogues to block receptors for microbial pathogenic determinants |
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GBGB0422003.4A GB0422003D0 (en) | 2004-10-05 | 2004-10-05 | Inhibitory analogues to block receptors for microbial pathogenic determinants |
GB0422003.4 | 2004-10-05 |
Publications (2)
Publication Number | Publication Date |
---|---|
WO2006038007A2 WO2006038007A2 (en) | 2006-04-13 |
WO2006038007A3 true WO2006038007A3 (en) | 2006-08-17 |
Family
ID=33428034
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PCT/GB2005/003836 WO2006038007A2 (en) | 2004-10-05 | 2005-10-05 | Inhibitory analogues to block receptors for microbial pathogenic determinants |
Country Status (2)
Country | Link |
---|---|
GB (2) | GB0422003D0 (en) |
WO (1) | WO2006038007A2 (en) |
Citations (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO1998059053A1 (en) * | 1997-06-20 | 1998-12-30 | Queen Mary & Westfield College | Immonogenic fragments of toxin a of clostridium difficile |
WO2000061761A2 (en) * | 1999-04-09 | 2000-10-19 | Techlab, Inc. | Recombinant clostridium toxin a protein carrier for polysaccharide conjugate vaccines |
US20030129198A1 (en) * | 1999-04-09 | 2003-07-10 | Wilkins Tracy D. | Methods to produce high levels of C. difficile toxins |
-
2004
- 2004-10-05 GB GBGB0422003.4A patent/GB0422003D0/en not_active Ceased
-
2005
- 2005-10-05 WO PCT/GB2005/003836 patent/WO2006038007A2/en active Application Filing
-
2007
- 2007-05-04 GB GB0708711A patent/GB2434580A/en not_active Withdrawn
Patent Citations (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO1998059053A1 (en) * | 1997-06-20 | 1998-12-30 | Queen Mary & Westfield College | Immonogenic fragments of toxin a of clostridium difficile |
WO2000061761A2 (en) * | 1999-04-09 | 2000-10-19 | Techlab, Inc. | Recombinant clostridium toxin a protein carrier for polysaccharide conjugate vaccines |
US20030129198A1 (en) * | 1999-04-09 | 2003-07-10 | Wilkins Tracy D. | Methods to produce high levels of C. difficile toxins |
Non-Patent Citations (4)
Title |
---|
CASTAGLIUOLO IGNAZIO ET AL: "A receptor decoy inhibits the enterotoxic effects of Clostridium difficile Toxin A in rat ileum", GASTROENTEROLOGY, vol. 111, no. 2, 1996, pages 433 - 438, XP002383253, ISSN: 0016-5085 * |
KINK J A ET AL: "ANTIBODIES TO RECOMBINANT CLOSTRIDIUM DIFFICILE TOXINS A AND B ARE EFFECTIVE TREATMENT AND PREVENT RELAPSE OF C. DIFFICILE-ASSOCIATED DISEASE IN A HAMSTER MODEL OF INFECTION", INFECTION AND IMMUNITY, AMERICAN SOCIETY FOR MICROBIOLOGY. WASHINGTON, US, vol. 66, no. 5, 1 May 1998 (1998-05-01), pages 2018 - 2025, XP002912254, ISSN: 0019-9567 * |
SAUERBORN MARKUS ET AL: "The C-terminal ligand-binding domain of Clostridium difficile toxin A (TcdA) abrogates TcdA-specific binding to cells and prevents mouse lethality", FEMS MICROBIOLOGY LETTERS, vol. 155, no. 1, 1 October 1997 (1997-10-01), pages 45 - 54, XP002383252, ISSN: 0378-1097 * |
WARD STEPHEN J ET AL: "Local and systemic neutralizing antibody responses induced by intranasal immunization with the nontoxic binding domain of toxin A from Clostridium difficile", INFECTION AND IMMUNITY, vol. 67, no. 10, October 1999 (1999-10-01), pages 5124 - 5132, XP002383254, ISSN: 0019-9567 * |
Also Published As
Publication number | Publication date |
---|---|
GB0708711D0 (en) | 2007-06-20 |
GB2434580A (en) | 2007-08-01 |
WO2006038007A2 (en) | 2006-04-13 |
GB0422003D0 (en) | 2004-11-03 |
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