WO2006034468A8 - Procedes et compositions pour le traitement de troubles hyperglycemiques, hyperlipidemiques, ou hyperinsulinemiques - Google Patents

Procedes et compositions pour le traitement de troubles hyperglycemiques, hyperlipidemiques, ou hyperinsulinemiques

Info

Publication number
WO2006034468A8
WO2006034468A8 PCT/US2005/034225 US2005034225W WO2006034468A8 WO 2006034468 A8 WO2006034468 A8 WO 2006034468A8 US 2005034225 W US2005034225 W US 2005034225W WO 2006034468 A8 WO2006034468 A8 WO 2006034468A8
Authority
WO
WIPO (PCT)
Prior art keywords
disorders
compositions
hyperinsulinemic
hyperlipidemic
methods
Prior art date
Application number
PCT/US2005/034225
Other languages
English (en)
Other versions
WO2006034468A3 (fr
WO2006034468A9 (fr
WO2006034468A2 (fr
Inventor
Xiaozhuo Chen
Klaus Himmeldirk
Yulin Ren
Original Assignee
Univ Ohio
Xiaozhuo Chen
Klaus Himmeldirk
Yulin Ren
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Ohio, Xiaozhuo Chen, Klaus Himmeldirk, Yulin Ren filed Critical Univ Ohio
Priority to CA2581485A priority Critical patent/CA2581485C/fr
Priority to US11/575,938 priority patent/US7687472B2/en
Priority to GB0707437A priority patent/GB2433935B/en
Publication of WO2006034468A2 publication Critical patent/WO2006034468A2/fr
Publication of WO2006034468A3 publication Critical patent/WO2006034468A3/fr
Publication of WO2006034468A8 publication Critical patent/WO2006034468A8/fr
Publication of WO2006034468A9 publication Critical patent/WO2006034468A9/fr

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/70Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7024Esters of saccharides
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H13/00Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids
    • C07H13/02Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids by carboxylic acids
    • C07H13/08Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids by carboxylic acids having the esterifying carboxyl radicals directly attached to carbocyclic rings
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/04Anorexiants; Antiobesity agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/06Antihyperlipidemics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/08Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Diabetes (AREA)
  • Engineering & Computer Science (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Obesity (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Hematology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Molecular Biology (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • Genetics & Genomics (AREA)
  • Epidemiology (AREA)
  • Emergency Medicine (AREA)
  • Endocrinology (AREA)
  • Child & Adolescent Psychology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Steroid Compounds (AREA)

Abstract

La présente invention a trait à des procédés de traitement de troubles hyperglycémiques, hyperlipidémiques, ou hyperinsulinémiques. L'invention a également trait à des compositions pour le traitement de tels troubles. Les compositions peuvent inclure des variants d'hexose et de pentose ayant des groupes fonctionnels acides et un substituant Y lié à la position six d'un hexose ou la position cinq du pentose.
PCT/US2005/034225 2004-09-23 2005-09-23 Procedes et compositions pour le traitement de troubles hyperglycemiques, hyperlipidemiques, ou hyperinsulinemiques WO2006034468A2 (fr)

Priority Applications (3)

Application Number Priority Date Filing Date Title
CA2581485A CA2581485C (fr) 2004-09-23 2005-09-23 Procedes et compositions pour le traitement de troubles hyperglycemiques, hyperlipidemiques, ou hyperinsulinemiques
US11/575,938 US7687472B2 (en) 2004-09-23 2005-09-23 Methods and compositions for treating hyperglycemic, hyperlipidemic, or hyperinsulinemic disorders
GB0707437A GB2433935B (en) 2004-09-23 2005-09-23 Compounds for treating diabetes and related disorders

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US61235404P 2004-09-23 2004-09-23
US60/612,354 2004-09-23

Publications (4)

Publication Number Publication Date
WO2006034468A2 WO2006034468A2 (fr) 2006-03-30
WO2006034468A3 WO2006034468A3 (fr) 2006-04-20
WO2006034468A8 true WO2006034468A8 (fr) 2006-05-18
WO2006034468A9 WO2006034468A9 (fr) 2006-07-27

Family

ID=36090702

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2005/034225 WO2006034468A2 (fr) 2004-09-23 2005-09-23 Procedes et compositions pour le traitement de troubles hyperglycemiques, hyperlipidemiques, ou hyperinsulinemiques

Country Status (4)

Country Link
US (1) US7687472B2 (fr)
CA (1) CA2581485C (fr)
GB (1) GB2433935B (fr)
WO (1) WO2006034468A2 (fr)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2007518821A (ja) 2004-01-23 2007-07-12 オハイオ ユニバーシティー Pggの分離および精製

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2005538987A (ja) * 2002-07-24 2005-12-22 オハイオ ユニバーシティー 真性糖尿病を処置するための方法および組成物
US20040258773A1 (en) * 2002-09-03 2004-12-23 Xiaozhuo Chen Composition and methods for treating subjects with hyperglycemia

Also Published As

Publication number Publication date
GB2433935A (en) 2007-07-11
CA2581485A1 (fr) 2006-03-30
US20070293439A1 (en) 2007-12-20
WO2006034468A3 (fr) 2006-04-20
GB0707437D0 (en) 2007-05-23
CA2581485C (fr) 2013-07-16
WO2006034468A9 (fr) 2006-07-27
GB2433935B (en) 2009-04-08
WO2006034468A2 (fr) 2006-03-30
US7687472B2 (en) 2010-03-30

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