WO2006028986A2 - Device and method for distraction of the spinal disc space - Google Patents

Device and method for distraction of the spinal disc space Download PDF

Info

Publication number
WO2006028986A2
WO2006028986A2 PCT/US2005/031356 US2005031356W WO2006028986A2 WO 2006028986 A2 WO2006028986 A2 WO 2006028986A2 US 2005031356 W US2005031356 W US 2005031356W WO 2006028986 A2 WO2006028986 A2 WO 2006028986A2
Authority
WO
WIPO (PCT)
Prior art keywords
filling member
holding portion
spinal disc
medicine
opening
Prior art date
Application number
PCT/US2005/031356
Other languages
French (fr)
Other versions
WO2006028986A3 (en
Inventor
Philip S. Yuan
Kwan Ku Lin
Robert M. Scribner
Original Assignee
Crosstrees Medical, Inc.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Crosstrees Medical, Inc. filed Critical Crosstrees Medical, Inc.
Priority to JP2007530405A priority Critical patent/JP2008511422A/en
Priority to EP05794205A priority patent/EP1793769A4/en
Priority to US11/574,562 priority patent/US7749230B2/en
Publication of WO2006028986A2 publication Critical patent/WO2006028986A2/en
Publication of WO2006028986A3 publication Critical patent/WO2006028986A3/en
Priority to US12/829,500 priority patent/US7993345B2/en
Priority to US13/195,483 priority patent/US20110288530A1/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02—Prostheses implantable into the body
    • A61F2/30—Joints
    • A61F2/44—Joints for the spine, e.g. vertebrae, spinal discs
    • A61F2/442—Intervertebral or spinal discs, e.g. resilient
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02—Prostheses implantable into the body
    • A61F2/30—Joints
    • A61F2/44—Joints for the spine, e.g. vertebrae, spinal discs
    • A61F2/441—Joints for the spine, e.g. vertebrae, spinal discs made of inflatable pockets or chambers filled with fluid, e.g. with hydrogel
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02—Prostheses implantable into the body
    • A61F2/30—Joints
    • A61F2002/30001—Additional features of subject-matter classified in A61F2/28, A61F2/30 and subgroups thereof
    • A61F2002/30667—Features concerning an interaction with the environment or a particular use of the prosthesis
    • A61F2002/30677—Means for introducing or releasing pharmaceutical products, e.g. antibiotics, into the body
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02—Prostheses implantable into the body
    • A61F2/30—Joints
    • A61F2/44—Joints for the spine, e.g. vertebrae, spinal discs
    • A61F2/442—Intervertebral or spinal discs, e.g. resilient
    • A61F2002/444—Intervertebral or spinal discs, e.g. resilient for replacing the nucleus pulposus

Definitions

  • the present invention relates generally to an instrument which is used in the restorative surgical treatment of spine disorder. More specifically this surgical instrument can be used to insert a medical material into a spinal disc such that the instrument can be separated from the medical material and drawn out of the spinal disc, and the medical material remains in the spinal disc in a restorative function.
  • the surgical treatment of spinal disc disorder can be generally attained by several methods, which include the hypodermic injection of medicine, the balloon-insertion of medicine, and the filler-insertion of medicine.
  • the U.S. Patent Nos. 5,976,186, 6,508,839, and 6,602,291 disclose respectively methods for treating disorders of the spinal disc, such as placement of a prosthetic device or reconstruction of the damaged structure of the disc. These methods are defective in design in that disc disruption is required for placement of the therapeutic implant.
  • the placement of a therapeutic implant by controlled delivery of a flowable material requiring minimal disruption of the disc is desirable. Without controlled delivery, the medicine is not contained and there is the possibility of injury to the surrounding tissues.
  • the filler-insertion method is used to implant material in the spinal disc in such a way that the material is contained in the spinal disc, and that the material only remains implanted in the spinal disc.
  • An extractable device for inserting a medicinal filling into a spinal disc comprising: a filling member comprising a flexible wall and provided with a holding portion, an injection port at one end of the holding portion, and an opening at another end of the holding portion; one or more thread, each having one end for fastening releasably said opening of said holding portion in such a manner that said opening is leakproof; and a flowable medicine to be injected into said holding portion via said injection port of said filling member in the wake of a process for inserting said filling member into the spinal disc whereby said flowable medicine solidifies in said holding portion of said filling member; said opening of said holding portion being unfastened at the time when other end of said threads is pulled by an external force, thereby enabling said filling member to be extracted from the spinal disc so as to leave only said flowable material in the spinal disc; wherein the volume of said holding portion of said filling member is filled and is substantially tubular after being filled, wherein cross sections perpendicular to a longitudinal axis
  • said flexible wall is provided with a plurality of through holes and is permeable.
  • Said flexible and permeable wall is of a one-layered or multi-layered construction.
  • said flowable medicine is a polymer substance such as a mixture which is flowable prior to setting to a non-viscous state such as PMMA, silicone, polyurethane, polyester, or other polymer.
  • the device of the present invention further comprises an injection tool for injecting said flowable medicine into said holding portion via said injection port.
  • said injection tool comprises a guide tube and a syringe, wherein one end of said guide tube is connected to said injection port of said filling member and another end of said guide tube is connected to said syringe in which said flowable medicine is held, so that said flowable medicine is able to be injected into said holding portion of said filling member by said syringe via said injection port and said guide tube.
  • the device of the present invention further comprises a working tube for inserting into said spinal disc, so that said filling member together with said guide tube can be inserted into said working tube and said filling member can be disposed in said spinal disc.
  • said tubular wall is provided with a plurality of through holes and is permeable.
  • the present invention also discloses a method for implanting a solidified medicine into a spinal disc comprising: inserting a filling member in a hole of a spinal disc, said filling member comprising a flexible and permeable wall and provided with a holding portion, an injection port at one end of the holding portion, and an opening at another end of the holding portion, wherein one or more thread is provided and each having one end fastening releasably said opening of said holding portion in such a manner that said opening is leakproof, wherein said holding portion of said filling member is substantially tubular after being filled, wherein cross sections perpendicular to a longitudinal axis of the holding portion are substantially elliptical along a direction from the injection port to the opening of the holding portion; injecting a flowable medicine into said holding portion via said injection port of said filling member, so that said holding portion is inflated and said flowable medicine solidifies in said holding portion of said filling member
  • the method of the present invention further comprises fastening detachably an injection tool with said filling member, so that said flowable medicine is injected into said holding portion via said injection tool.
  • said injection tool comprises a guide tube and a syringe, wherein one end of said guide tube is connected to said injection port of said filling member and another end of said guide tube is connected to said syringe in which said flowable medicine is held, wherein said flowable medicine is injected into said holding portion of said filling member by said syringe via said injection port and said guide tube.
  • the method of the present invention further comprises inserting a working tube in said hole of said spinal disc, and inserting said filling member together with said guide tube into said working tube, so that said filling member is disposed in said spinal disc.
  • the flexible wall of the filling member of the present invention is made of a biocompatible or biosynthetic material, such as polymer, rubber, elastic plastic, PTFE, Dacron, and like materials.
  • the flexible wall is provided with a plurality of pores and is therefore permeable. Pores may be provided by fabricating the wall from a weave of selected material, or by perforation of a film of selected material.
  • the flexible wall can be formed into an object in the form of sac, bag, ball, cylinder or rectangular column integrally or by joining separate pieces.
  • the filling member of the present invention may contain a radiopaque material, such as a metal wire, by which the precise position of the filling member can be easily located by an imaging system, such as X-ray imaging equipment.
  • a radiopaque material such as a metal wire
  • the flexible wall of the filling member of the present invention may be of a one-layered or multi-layered construction, depending on the particle size and the viscosity of the medicine. If the particle size of the medicine is relatively large, the flexible wall is preferably of a two-layered construction. If the viscosity of the medicine is relatively high, the flexible wall is also preferably of a two-layered construction. On the other hand, the flexible wall is preferably of a three-layered or four-layered construction under the circumstances that the particle size of the medicine is relatively small and that the viscosity of the medicine is relatively lower.
  • FIG. 2 is schematic view illustrating the lashing of the opening of the holding portion of the filling member of the present invention.
  • FIG. 3a shows a longitudinal sectional view of a one-layered wall of the filling member of the present invention.
  • FIG. 3b shows a longitudinal sectional view of a multi-layered wall of the filling member of the present invention.
  • FIG. 4a shows a sectional view of the filling member placed within the spinal disc.
  • Fig. 4b shows a sectional view of the filling member placed within the spinal disc containing a full volume of flowable material.
  • FIG. 5a shows a sectional view of the filling member with the said opening in the open condition.
  • FIG 5b is a sectional view showing the removal of the filling member from the spinal disc.
  • FIG. 6a is a sectional view showing the flowable material within the spinal disc.
  • FIG. 6b is a sectional view showing the flowable material at more than one location within the spinal disc.
  • an extractable filler 10 embodied in the present invention comprises a filling member 20, a flowable medicine 30, a guide tube 40, and two threads 50 and 51.
  • the filling member 20 is formed of a flexible wall 21 and is provided with a holding portion 22 and an injection port 23.
  • the flexible wall 21 may be made of rubber or a flexible plastic material with perforated holes, or a woven fabric.
  • the flowable medicine 30 is injected into the holding portion 22 via the guide tube 40 and the injection port 23.
  • the dotted line 3-3 shows a direction in which a section of the filling member 20 is taken.
  • the holding portion 22 of the filling member is taken.
  • the 20 is provided with an opening 24 opposite to the injection port 23 of the filling member 40.
  • the opening 24 is lashed by two threads 50 and 51.
  • the first thread 50 has a first end 501 and a second end 502, while the second thread 51 has a first end 511 and a second end 512.
  • the two threads 50 and 51 are in fact fastened releasably to the flexible wall 21 near the opening 24. The way by which they are fastened together is not shown in the drawing.
  • the opening 24 of the holding portion 22 of the filling member 20 is securely tied up to prevent the medicine 30 from leaking out of the holding portion 22 by means of the two threads 50 and 51 which are releasably entangled in such a manner that the first end 511 of the second thread 51 is wound around the first thread 50.
  • the flexible wall 21 surrounding the opening 24 is located in a position between the two threads 50 and 51.
  • both ends 501 and 502 of the first thread 50, and the first end 511 of the second thread 51 are respectively pulled rightward and leftwards at the same time, as illustrated in FIG. 2.
  • the opening 24 of the filling member 20 is ieakproof.
  • the opening 24 of the filling member 20 is untied when the second end 512 of the second thread 51 is pulled in the direction of the injection port 23. As a result, the two threads 50 and 51 become loosened. Thereafter, the first end 501 of the first thread 50 and the second end 512 of the second thread 51 are respectively pulled in a direction away from the opening 24 of the filling member 20, as illustrated in FIG. 5a. The opening 24 is thus unfastened completely.
  • the flexible wall 21 of the filling member 20 is of a one-layered construction, as shown in FIG. 3a, or of a multi-layered construction, as shown in FIG. 3b.
  • the flexible wall 21 is provided with a plurality of pores 211 permeable to fluids. If the flexible wall 21 is of a multi-layered construction, the flexible walls 21 are laminated in such a way that the pores 211 are not corresponding in location to slow down the passage of the fluids.
  • the filling member 20 of the extractable filler 10 is inserted into a hole 71 formed on a spinal disc 70, wherein a working tube 51 is inserted into the hole 71 in advance to accommodate the guide tube 40, the threads 50 and 51 and the filling member 20.
  • the flowable medicine is then injected into the holding portion 21 of the filling member 20 by a syringe in conjunction with the guide tube 40.
  • the guide tube 40 has one end 41 in the holding portion 21 , and another end 42 connected to one end 611 of a barrel 612 of the syringe 80.
  • a plunger 62 is inserted into another end of the barrel 612 in which the pasty medicine 30 is contained.
  • the filling member 20 is thus inflated by the medicine 30, as shown in FIGs. 4a and 4b.
  • said flowable medicine 30 is a polymer substance such as a mixture which is flowable prior to setting to a non-viscous state such as PMMA, silicone, polyurethane, polyester, or other polymer.
  • the filling member 20 Upon completion of the solidification of the pasty medicine 30 in the filling member 20 within the spinal disc 70, the filling member 20 must be extracted from the hole 71 of the spinal disc 70, so as to leave only the medicine 30 in the spinal disc 70.
  • the extraction of the filling member 20 from the hole 71 of the spinal disc 70 involves a first step in which the second end 512 of the second thread 51 is pulled in the direction of the filler opening 23. As a result, the two threads 50 and 51 become loosened. Thereafter, the first end 501 of the first thread 50 and the second end 512 of the second thread 51 are respectively pulled in a direction away from the opening 24 of the filling member 20, as illustrated in FIG. 5a. The opening 24 is thus unfastened completely.
  • the flexible wall 21 is retreated from the solidified medicine 30 by pulling one end of the flexible wall 21 connected to the guide tube 40 at the injection port 23 of said holding portion of the said filling member 20, whereby said solidified medicine 30 is released from said filling member 20 and is disposed in the spinal disc 70, as shown in FIG. 5b.
  • the filling member and the guide tube 40 are pulled from the hole 71 of the spinal disc 70, so as to leave only said solidified medicine 30 in the spinal disc 70.
  • the flexible wall 21 of the filling member 20 of the extractable filler 10 of the present invention may have a curved profile. As shown in FIG. 6a, the flowable material 30 injected into the filling member 20 in the spinal disc 70 will also have a curved profile when remaining within the spinal disc 70.
  • the filling member 20 may be placed at more than one location in the spinal disc, with the flowable material 30 remaining at more than one location in the spinal disc 70.

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Cardiology (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Transplantation (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Vascular Medicine (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Prostheses (AREA)
  • Surgical Instruments (AREA)

Abstract

An extractable device is used to insert a medicinal filling into a spinal disc. The device comprises a filling member and a flowable medicine. The filling member is made of a flexible and permeable wall and is provided with a holding portion and an injection port via which the flowable medicine is injected into the holding portion after the filling member is inserted into the spinal disc. The holding portion is provided with an opening which is releasably lashed by one end of one or more threads so as to make the opening leakproof. Upon completion of solidification of the flowable medicine in the holding portion of the filling member, other end of the thread is pulled to unlash the opening of the holding portion, thereby enabling the filling member to be extracted from the spinal disc so as to leave only the medicine in the spinal disc.

Description

Device and Method for Distraction of the Spinal Disc Space
FIELD OF THE INVENTION
The present invention relates generally to an instrument which is used in the restorative surgical treatment of spine disorder. More specifically this surgical instrument can be used to insert a medical material into a spinal disc such that the instrument can be separated from the medical material and drawn out of the spinal disc, and the medical material remains in the spinal disc in a restorative function.
BACKGROUND OF THE INVENTION The surgical treatment of spinal disc disorder can be generally attained by several methods, which include the hypodermic injection of medicine, the balloon-insertion of medicine, and the filler-insertion of medicine. For example, the U.S. Patent Nos. 5,976,186, 6,508,839, and 6,602,291 disclose respectively methods for treating disorders of the spinal disc, such as placement of a prosthetic device or reconstruction of the damaged structure of the disc. These methods are defective in design in that disc disruption is required for placement of the therapeutic implant. The placement of a therapeutic implant by controlled delivery of a flowable material requiring minimal disruption of the disc is desirable. Without controlled delivery, the medicine is not contained and there is the possibility of injury to the surrounding tissues.
In order to prevent the drawbacks of the methods described above, the filler-insertion method is used to implant material in the spinal disc in such a way that the material is contained in the spinal disc, and that the material only remains implanted in the spinal disc. SUMMARY OF THE INVENTION
An extractable device for inserting a medicinal filling into a spinal disc, said device comprising: a filling member comprising a flexible wall and provided with a holding portion, an injection port at one end of the holding portion, and an opening at another end of the holding portion; one or more thread, each having one end for fastening releasably said opening of said holding portion in such a manner that said opening is leakproof; and a flowable medicine to be injected into said holding portion via said injection port of said filling member in the wake of a process for inserting said filling member into the spinal disc whereby said flowable medicine solidifies in said holding portion of said filling member; said opening of said holding portion being unfastened at the time when other end of said threads is pulled by an external force, thereby enabling said filling member to be extracted from the spinal disc so as to leave only said flowable material in the spinal disc; wherein the volume of said holding portion of said filling member is filled and is substantially tubular after being filled, wherein cross sections perpendicular to a longitudinal axis of the holding portion are substantially elliptical along a direction from the injection port to the opening of the holding portion.
Preferably, said flexible wall is provided with a plurality of through holes and is permeable. Said flexible and permeable wall is of a one-layered or multi-layered construction. Preferably, said flowable medicine is a polymer substance such as a mixture which is flowable prior to setting to a non-viscous state such as PMMA, silicone, polyurethane, polyester, or other polymer.
Preferably, the device of the present invention further comprises an injection tool for injecting said flowable medicine into said holding portion via said injection port.
Preferably, said injection tool comprises a guide tube and a syringe, wherein one end of said guide tube is connected to said injection port of said filling member and another end of said guide tube is connected to said syringe in which said flowable medicine is held, so that said flowable medicine is able to be injected into said holding portion of said filling member by said syringe via said injection port and said guide tube.
Preferably, the device of the present invention further comprises a working tube for inserting into said spinal disc, so that said filling member together with said guide tube can be inserted into said working tube and said filling member can be disposed in said spinal disc.
Preferably, said tubular wall is provided with a plurality of through holes and is permeable. The present invention also discloses a method for implanting a solidified medicine into a spinal disc comprising: inserting a filling member in a hole of a spinal disc, said filling member comprising a flexible and permeable wall and provided with a holding portion, an injection port at one end of the holding portion, and an opening at another end of the holding portion, wherein one or more thread is provided and each having one end fastening releasably said opening of said holding portion in such a manner that said opening is leakproof, wherein said holding portion of said filling member is substantially tubular after being filled, wherein cross sections perpendicular to a longitudinal axis of the holding portion are substantially elliptical along a direction from the injection port to the opening of the holding portion; injecting a flowable medicine into said holding portion via said injection port of said filling member, so that said holding portion is inflated and said flowable medicine solidifies in said holding portion of said filling member; and unfastening said opening of said holding portion by pulling other end of said threads, thereby enabling said filling member to be extracted from the spinal disc so as to leave only said solidified medicine in the spinal disc, wherein said solidified flowable medicine has a shape similar to that of the inflated holding portion. Preferably, the method of the present invention further comprises fastening detachably an injection tool with said filling member, so that said flowable medicine is injected into said holding portion via said injection tool. More preferably, said injection tool comprises a guide tube and a syringe, wherein one end of said guide tube is connected to said injection port of said filling member and another end of said guide tube is connected to said syringe in which said flowable medicine is held, wherein said flowable medicine is injected into said holding portion of said filling member by said syringe via said injection port and said guide tube.
Preferably, the method of the present invention further comprises inserting a working tube in said hole of said spinal disc, and inserting said filling member together with said guide tube into said working tube, so that said filling member is disposed in said spinal disc. The flexible wall of the filling member of the present invention is made of a biocompatible or biosynthetic material, such as polymer, rubber, elastic plastic, PTFE, Dacron, and like materials. The flexible wall is provided with a plurality of pores and is therefore permeable. Pores may be provided by fabricating the wall from a weave of selected material, or by perforation of a film of selected material. The flexible wall can be formed into an object in the form of sac, bag, ball, cylinder or rectangular column integrally or by joining separate pieces.
The filling member of the present invention may contain a radiopaque material, such as a metal wire, by which the precise position of the filling member can be easily located by an imaging system, such as X-ray imaging equipment.
The flexible wall of the filling member of the present invention may be of a one-layered or multi-layered construction, depending on the particle size and the viscosity of the medicine. If the particle size of the medicine is relatively large, the flexible wall is preferably of a two-layered construction. If the viscosity of the medicine is relatively high, the flexible wall is also preferably of a two-layered construction. On the other hand, the flexible wall is preferably of a three-layered or four-layered construction under the circumstances that the particle size of the medicine is relatively small and that the viscosity of the medicine is relatively lower. The features and the advantages of the present invention will be more readily understood upon a thoughtful deliberation of the following detailed description of the preferred embodiments of the present invention with reference to the accompanying drawings. BRlEF DESCRIPTION OF THE DRAWINGS FIG. 1 shows a schematic view of an extractable filler of the present invention.
FIG. 2 is schematic view illustrating the lashing of the opening of the holding portion of the filling member of the present invention.
FIG. 3a shows a longitudinal sectional view of a one-layered wall of the filling member of the present invention.
FIG. 3b shows a longitudinal sectional view of a multi-layered wall of the filling member of the present invention. FIG. 4a shows a sectional view of the filling member placed within the spinal disc.
Fig. 4b shows a sectional view of the filling member placed within the spinal disc containing a full volume of flowable material.
FIG. 5a shows a sectional view of the filling member with the said opening in the open condition.
FIG 5b is a sectional view showing the removal of the filling member from the spinal disc.
FIG. 6a is a sectional view showing the flowable material within the spinal disc. FIG. 6b is a sectional view showing the flowable material at more than one location within the spinal disc.
DETAILED DESCRIPTION OF THE PREFERRED EMBODIMENTS
As shown in FIG. 1 , an extractable filler 10 embodied in the present invention comprises a filling member 20, a flowable medicine 30, a guide tube 40, and two threads 50 and 51. The filling member 20 is formed of a flexible wall 21 and is provided with a holding portion 22 and an injection port 23. The flexible wall 21 may be made of rubber or a flexible plastic material with perforated holes, or a woven fabric. The flowable medicine 30 is injected into the holding portion 22 via the guide tube 40 and the injection port 23. The dotted line 3-3 shows a direction in which a section of the filling member 20 is taken. As shown in FIG. 2, the holding portion 22 of the filling member
20 is provided with an opening 24 opposite to the injection port 23 of the filling member 40. The opening 24 is lashed by two threads 50 and 51. The first thread 50 has a first end 501 and a second end 502, while the second thread 51 has a first end 511 and a second end 512. The two threads 50 and 51 are in fact fastened releasably to the flexible wall 21 near the opening 24. The way by which they are fastened together is not shown in the drawing.
The opening 24 of the holding portion 22 of the filling member 20 is securely tied up to prevent the medicine 30 from leaking out of the holding portion 22 by means of the two threads 50 and 51 which are releasably entangled in such a manner that the first end 511 of the second thread 51 is wound around the first thread 50. Upon completion of the winding process, the flexible wall 21 surrounding the opening 24 is located in a position between the two threads 50 and 51. Thereafter, both ends 501 and 502 of the first thread 50, and the first end 511 of the second thread 51 are respectively pulled rightward and leftwards at the same time, as illustrated in FIG. 2. As a result, the opening 24 of the filling member 20 is ieakproof. The opening 24 of the filling member 20 is untied when the second end 512 of the second thread 51 is pulled in the direction of the injection port 23. As a result, the two threads 50 and 51 become loosened. Thereafter, the first end 501 of the first thread 50 and the second end 512 of the second thread 51 are respectively pulled in a direction away from the opening 24 of the filling member 20, as illustrated in FIG. 5a. The opening 24 is thus unfastened completely.
The flexible wall 21 of the filling member 20 is of a one-layered construction, as shown in FIG. 3a, or of a multi-layered construction, as shown in FIG. 3b. The flexible wall 21 is provided with a plurality of pores 211 permeable to fluids. If the flexible wall 21 is of a multi-layered construction, the flexible walls 21 are laminated in such a way that the pores 211 are not corresponding in location to slow down the passage of the fluids. As shown in FIG. 4a, the filling member 20 of the extractable filler 10 is inserted into a hole 71 formed on a spinal disc 70, wherein a working tube 51 is inserted into the hole 71 in advance to accommodate the guide tube 40, the threads 50 and 51 and the filling member 20. The flowable medicine is then injected into the holding portion 21 of the filling member 20 by a syringe in conjunction with the guide tube 40. The guide tube 40 has one end 41 in the holding portion 21 , and another end 42 connected to one end 611 of a barrel 612 of the syringe 80. A plunger 62 is inserted into another end of the barrel 612 in which the pasty medicine 30 is contained. The filling member 20 is thus inflated by the medicine 30, as shown in FIGs. 4a and 4b.
Preferably, said flowable medicine 30 is a polymer substance such as a mixture which is flowable prior to setting to a non-viscous state such as PMMA, silicone, polyurethane, polyester, or other polymer.
Upon completion of the solidification of the pasty medicine 30 in the filling member 20 within the spinal disc 70, the filling member 20 must be extracted from the hole 71 of the spinal disc 70, so as to leave only the medicine 30 in the spinal disc 70. The extraction of the filling member 20 from the hole 71 of the spinal disc 70 involves a first step in which the second end 512 of the second thread 51 is pulled in the direction of the filler opening 23. As a result, the two threads 50 and 51 become loosened. Thereafter, the first end 501 of the first thread 50 and the second end 512 of the second thread 51 are respectively pulled in a direction away from the opening 24 of the filling member 20, as illustrated in FIG. 5a. The opening 24 is thus unfastened completely.
After the opening 24 being unfastened, the flexible wall 21 is retreated from the solidified medicine 30 by pulling one end of the flexible wall 21 connected to the guide tube 40 at the injection port 23 of said holding portion of the said filling member 20, whereby said solidified medicine 30 is released from said filling member 20 and is disposed in the spinal disc 70, as shown in FIG. 5b. The filling member and the guide tube 40 are pulled from the hole 71 of the spinal disc 70, so as to leave only said solidified medicine 30 in the spinal disc 70.
The flexible wall 21 of the filling member 20 of the extractable filler 10 of the present invention may have a curved profile. As shown in FIG. 6a, the flowable material 30 injected into the filling member 20 in the spinal disc 70 will also have a curved profile when remaining within the spinal disc 70.
As shown in FIG. 6b, the filling member 20 may be placed at more than one location in the spinal disc, with the flowable material 30 remaining at more than one location in the spinal disc 70.
The above embodiments are, in all respects, illustrative and nonrestrictive. The invention may be embodied in other specific forms without deviating from the scope of the following claims.

Claims

WHAT IS CLAIMED IS:
1. An extractable device for inserting a medicinal filling into a spinal disc, said device comprising: a filling member comprising a flexible wall and provided with a holding portion, an injection port at one end of the holding portion, and an opening at another end of the holding portion; one or more thread fastening releasably said opening of said holding portion in such a manner that said opening is leakproof; and a flowable medicine to be injected into said holding portion via said injection port of said filling member in the wake of a process for inserting said filling member into the spinal disc; said opening of said holding portion being opened, thereby enabling said filling member to be extracted from the spinal disc so as to leave only said medicine in the spinal disc.
2. The device as defined in claim 1 , wherein said flexible wall is provided with a plurality of through holes and is permeable.
3. The device as defined in claim 2, wherein said flexible and permeable wall is of a one-layered or multi-layered construction.
4. The device as defined in claim 1 , wherein said flowable material is a polymer capable of setting to a non-viscous state.
5. The device as defined in claim 1 further comprising an injection tool for injecting said flowable medicine into said holding portion via said injection port.
6. The device as defined in claim 5, wherein said injection tool comprises a guide tube and a syringe, wherein one end of said guide tube is connected to said injection port of said filling member and another end of said guide tube is connected to said syringe in which said flowable medicine is held, so that said flowable medicine is able to be injected into said holding portion of said filling member by said syringe via said injection port and said guide tube.
7. The device as defined in claim 6 further comprising a working tube for inserting into said spinal disc, so that said filling member together with said guide tube can be inserted into said working tube and said filling member can be disposed in said spinal disc.
8. The device as defined in claim 3, wherein said tubular wall is provided with a plurality of through holes and is permeable.
9. A method for implanting a solidified medicine into a spinal disc comprising: inserting a filling member in a hole of a spinal disc, said filling member comprising a flexible and permeable wall and provided with a holding portion, an injection port at one end of the holding portion, and an opening at another end of the holding portion, wherein one or more thread is provided and each having one end fastening releasably said opening of said holding portion in such a manner that said opening is leakproof, wherein said holding portion of said filling member is inflatable; injecting a flowable medicine into said holding portion via said injection port of said filling member, so that said holding portion is inflated and said flowable medicine solidifies in said holding portion of said filling member; and unfastening said opening of said holding portion by pulling other end of said threads, thereby enabling said filling member to be extracted from the spinal disc so as to leave only said solidified medicine in the spinal disc, wherein said solidified flowable medicine has a shape similar to that of the inflated holding portion.
10. The method as defined in claim 9, wherein said flowable material is a polymer capable of setting to a non-viscous state.
1 1 . The method as defined in claim 9 further comprising fastening detachably an injection tool with said filling member, so that said flowable medicine is injected into said holding portion via said injection tool.
12. The method as defined in claim 1 1 , wherein said injection tool comprises a guide tube and a syringe, wherein one end of said guide tube is connected to said injection port of said filling member and another end of said guide tube is connected to said syringe in which said flowable medicine is held, wherein said flowable medicine is injected into said holding portion of said filling member by said syringe via said injection port and said guide tube.
13. The method as defined in claim 12 further comprising inserting a working tube in said hole of said spinal disc, and inserting said filling member together with said guide tube into said working tube, so that said filling member is disposed in said spinal disc.
PCT/US2005/031356 2004-09-02 2005-09-02 Device and method for distraction of the spinal disc space WO2006028986A2 (en)

Priority Applications (5)

Application Number Priority Date Filing Date Title
JP2007530405A JP2008511422A (en) 2004-09-02 2005-09-02 Device and method for distraction of spinal disc space
EP05794205A EP1793769A4 (en) 2004-09-02 2005-09-02 Device and method for distraction of the spinal disc space
US11/574,562 US7749230B2 (en) 2004-09-02 2005-09-02 Device and method for distraction of the spinal disc space
US12/829,500 US7993345B2 (en) 2004-09-02 2010-07-02 Device and method for distraction of the spinal disc space
US13/195,483 US20110288530A1 (en) 2004-09-02 2011-08-01 Device and method for distraction of the spinal disc space

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US60661104P 2004-09-02 2004-09-02
US60/606,611 2004-09-02

Related Child Applications (2)

Application Number Title Priority Date Filing Date
US11/574,562 A-371-Of-International US7749230B2 (en) 2004-09-02 2005-09-02 Device and method for distraction of the spinal disc space
US12/829,500 Continuation US7993345B2 (en) 2004-09-02 2010-07-02 Device and method for distraction of the spinal disc space

Publications (2)

Publication Number Publication Date
WO2006028986A2 true WO2006028986A2 (en) 2006-03-16
WO2006028986A3 WO2006028986A3 (en) 2006-06-01

Family

ID=36036876

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2005/031356 WO2006028986A2 (en) 2004-09-02 2005-09-02 Device and method for distraction of the spinal disc space

Country Status (5)

Country Link
US (3) US7749230B2 (en)
EP (1) EP1793769A4 (en)
JP (1) JP2008511422A (en)
CN (1) CN101257864A (en)
WO (1) WO2006028986A2 (en)

Cited By (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8623025B2 (en) 2006-12-15 2014-01-07 Gmedelaware 2 Llc Delivery apparatus and methods for vertebrostenting
US9113988B2 (en) 2003-05-21 2015-08-25 Crosstrees Medical, Inc. Method for inserting medicine into animal tissue
US9326806B2 (en) 2003-09-02 2016-05-03 Crosstrees Medical, Inc. Devices and methods for the treatment of bone fracture
US9433404B2 (en) 2012-10-31 2016-09-06 Suture Concepts Inc. Method and apparatus for closing fissures in the annulus fibrosus
US9480485B2 (en) 2006-12-15 2016-11-01 Globus Medical, Inc. Devices and methods for vertebrostenting
US9687255B2 (en) 2008-06-17 2017-06-27 Globus Medical, Inc. Device and methods for fracture reduction
US9949734B2 (en) 2012-10-31 2018-04-24 Suture Concepts Inc. Method and apparatus for closing a fissure in the annulus of an intervertebral disc, and/or for effecting other anatomical repairs and/or fixations
US10786235B2 (en) 2012-10-31 2020-09-29 Anchor Innovation Medical, Inc. Method and apparatus for closing a fissure in the annulus of an intervertebral disc, and/or for effecting other anatomical repairs and/or fixations

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2004100841A1 (en) 1999-08-18 2004-11-25 Intrinsic Therapeutics, Inc. Devices and method for augmenting a vertebral disc nucleus
CA2425951C (en) 1999-08-18 2008-09-16 Intrinsic Therapeutics, Inc. Devices and method for nucleus pulposus augmentation and retention
WO2009033100A1 (en) 2007-09-07 2009-03-12 Intrinsic Therapeutics, Inc. Bone anchoring systems
US7717961B2 (en) 1999-08-18 2010-05-18 Intrinsic Therapeutics, Inc. Apparatus delivery in an intervertebral disc
US7094258B2 (en) 1999-08-18 2006-08-22 Intrinsic Therapeutics, Inc. Methods of reinforcing an annulus fibrosis
US7972337B2 (en) * 2005-12-28 2011-07-05 Intrinsic Therapeutics, Inc. Devices and methods for bone anchoring
US8323341B2 (en) 2007-09-07 2012-12-04 Intrinsic Therapeutics, Inc. Impaction grafting for vertebral fusion
US7998213B2 (en) 1999-08-18 2011-08-16 Intrinsic Therapeutics, Inc. Intervertebral disc herniation repair
TWI235055B (en) * 2003-05-21 2005-07-01 Guan-Gu Lin Filling device capable of removing animal tissues
TW200511970A (en) * 2003-09-29 2005-04-01 Kwan-Ku Lin A spine wrapping and filling apparatus
JP2008511422A (en) * 2004-09-02 2008-04-17 クロストゥリーズ・メディカル・インコーポレーテッド Device and method for distraction of spinal disc space
US20070049849A1 (en) * 2005-05-24 2007-03-01 Schwardt Jeffrey D Bone probe apparatus and method of use
KR20080047357A (en) * 2005-07-07 2008-05-28 크로스트리스 메디칼, 인코포레이티드 Devices and methods for the treatment of bone fracture
US20090299476A1 (en) * 2006-05-19 2009-12-03 Ashish Diwan Tissue prosthesis
US8961553B2 (en) * 2007-09-14 2015-02-24 Crosstrees Medical, Inc. Material control device for inserting material into a targeted anatomical region
KR100977535B1 (en) 2008-05-13 2010-08-23 윤강준 An artificial nucleus pulposus in the middle of the spinal disc
US20100004745A1 (en) * 2008-07-01 2010-01-07 Doctors Research Group, Inc. Fusing Bone
US8864711B2 (en) * 2010-01-27 2014-10-21 Warsaw Orthopedic, Inc. Drug dispensing balloon for treating disc disease or pain
US8685106B2 (en) 2011-11-15 2014-04-01 Abraham Lin Method of a pharmaceutical delivery system for use within a joint replacement
US20130282121A1 (en) * 2012-03-22 2013-10-24 Ann Prewett Spinal facet augmentation implant and method
WO2015168186A1 (en) * 2014-04-28 2015-11-05 Bizwerks, Llc Led venue lighting system and method

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5976186A (en) 1994-09-08 1999-11-02 Stryker Technologies Corporation Hydrogel intervertebral disc nucleus
US6508839B1 (en) 1999-08-18 2003-01-21 Intrinsic Orthopedics, Inc. Devices and methods of vertebral disc augmentation
US6602291B1 (en) 1999-04-05 2003-08-05 Raymedica, Inc. Prosthetic spinal disc nucleus having a shape change characteristic
US20050043688A1 (en) 2003-08-19 2005-02-24 Gremel Robert F. Apparatus for retaining concentric parts within one another

Family Cites Families (81)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US632235A (en) * 1898-10-05 1899-09-05 William C Snow Magazine-firearm.
US2669230A (en) 1947-07-30 1954-02-16 Becton Dickinson Co Injection apparatus
US4188949A (en) 1977-07-05 1980-02-19 Becton, Dickinson & Company Sequential injection syringe
US4488549A (en) 1981-08-25 1984-12-18 University Of Exeter Pressurization of cement in bones
US4627434A (en) 1985-05-03 1986-12-09 Murray William M Bone cement system and method
US4969888A (en) 1989-02-09 1990-11-13 Arie Scholten Surgical protocol for fixation of osteoporotic bone using inflatable device
US5017175A (en) 1989-02-17 1991-05-21 Teepak, Inc. Brake-sizing devices for food stuffing apparatus and methods of use
US5054492A (en) 1990-12-17 1991-10-08 Cardiovascular Imaging Systems, Inc. Ultrasonic imaging catheter having rotational image correlation
US6248110B1 (en) 1994-01-26 2001-06-19 Kyphon, Inc. Systems and methods for treating fractured or diseased bone using expandable bodies
US6241734B1 (en) 1998-08-14 2001-06-05 Kyphon, Inc. Systems and methods for placing materials into bone
US7166121B2 (en) 1994-01-26 2007-01-23 Kyphon Inc. Systems and methods using expandable bodies to push apart cortical bone surfaces
US7044954B2 (en) 1994-01-26 2006-05-16 Kyphon Inc. Method for treating a vertebral body
US6716216B1 (en) 1998-08-14 2004-04-06 Kyphon Inc. Systems and methods for treating vertebral bodies
DE69535492T2 (en) 1994-01-26 2007-09-06 Kyphon Inc., Sunnyvale Improved inflatable device for use in surgical methods for fixation of bones
CA2180556C (en) 1994-01-26 2007-08-07 Mark A. Reiley Improved inflatable device for use in surgical protocol relating to fixation of bone
US20030032963A1 (en) 2001-10-24 2003-02-13 Kyphon Inc. Devices and methods using an expandable body with internal restraint for compressing cancellous bone
US5571189A (en) * 1994-05-20 1996-11-05 Kuslich; Stephen D. Expandable fabric implant for stabilizing the spinal motion segment
US5632275A (en) 1994-09-16 1997-05-27 Scribner-Browne Medical Design Incorporated Catheter lab table pad and method for using the same
US5744958A (en) 1995-11-07 1998-04-28 Iti Medical Technologies, Inc. Instrument having ultra-thin conductive coating and method for magnetic resonance imaging of such instrument
US5782764A (en) 1995-11-07 1998-07-21 Iti Medical Technologies, Inc. Fiber composite invasive medical instruments and methods for use in interventional imaging procedures
US6053904A (en) 1996-04-05 2000-04-25 Robert M. Scribner Thin wall catheter introducer system
EP0873145A2 (en) 1996-11-15 1998-10-28 Advanced Bio Surfaces, Inc. Biomaterial system for in situ tissue repair
US6712819B2 (en) 1998-10-20 2004-03-30 St. Francis Medical Technologies, Inc. Mating insertion instruments for spinal implants and methods of use
US6017366A (en) * 1997-04-18 2000-01-25 W. L. Gore & Associates, Inc. Resorbable interposition arthroplasty implant
US5972015A (en) 1997-08-15 1999-10-26 Kyphon Inc. Expandable, asymetric structures for deployment in interior body regions
GB9714580D0 (en) 1997-07-10 1997-09-17 Wardlaw Douglas Prosthetic intervertebral disc nucleus
US6048346A (en) 1997-08-13 2000-04-11 Kyphon Inc. Systems and methods for injecting flowable materials into bones
US6468279B1 (en) 1998-01-27 2002-10-22 Kyphon Inc. Slip-fit handle for hand-held instruments that access interior body regions
US6440138B1 (en) 1998-04-06 2002-08-27 Kyphon Inc. Structures and methods for creating cavities in interior body regions
US6719773B1 (en) 1998-06-01 2004-04-13 Kyphon Inc. Expandable structures for deployment in interior body regions
ATE484247T1 (en) 1998-06-01 2010-10-15 Kyphon S Rl UNFOLDABLE, PRE-FORMED STRUCTURES FOR UNFOLDING IN REGIONS WITHIN THE BODY
US20050228397A1 (en) 1998-08-14 2005-10-13 Malandain Hugues F Cavity filling device
US6146422A (en) 1999-01-25 2000-11-14 Lawson; Kevin Jon Prosthetic nucleus replacement for surgical reconstruction of intervertebral discs and treatment method
US6245107B1 (en) 1999-05-28 2001-06-12 Bret A. Ferree Methods and apparatus for treating disc herniation
AU5701200A (en) 1999-07-02 2001-01-22 Petrus Besselink Reinforced expandable cage
US6575919B1 (en) 1999-10-19 2003-06-10 Kyphon Inc. Hand-held instruments that access interior body regions
US7081122B1 (en) 1999-10-19 2006-07-25 Kyphon Inc. Hand-held instruments that access interior body regions
US6558390B2 (en) 2000-02-16 2003-05-06 Axiamed, Inc. Methods and apparatus for performing therapeutic procedures in the spine
US6740093B2 (en) * 2000-02-28 2004-05-25 Stephen Hochschuler Method and apparatus for treating a vertebral body
ES2262642T3 (en) 2000-04-05 2006-12-01 Kyphon Inc. DEVICE FOR THE TREATMENT OF FRACTURED AND / OR SICK BONES.
AU5318301A (en) 2000-04-07 2001-10-23 Kyphon Inc Insertion devices and method of use
US7815649B2 (en) 2000-04-07 2010-10-19 Kyphon SÀRL Insertion devices and method of use
US6533817B1 (en) 2000-06-05 2003-03-18 Raymedica, Inc. Packaged, partially hydrated prosthetic disc nucleus
CA2413325A1 (en) 2000-06-27 2002-01-03 Paul M. Sand Systems and methods for injecting flowable materials into bones
CN100486536C (en) 2000-07-14 2009-05-13 科丰公司 Systems for inducting material into bone
US20020068974A1 (en) 2000-07-21 2002-06-06 Kuslich Stephen D. Expandable porous mesh bag device and methods of use for reduction, filling, fixation and supporting of bone
AU2001293581A1 (en) * 2000-09-26 2002-04-08 Neurortho Implants Design, Llc Inter-vertebral disc prosthesis for lumbar rachis through posterior surgery thereof
CN100522091C (en) 2000-10-25 2009-08-05 科丰有限公司 Systems and methods for reducing fractured bone using a fracture reduction cannula
US6632235B2 (en) 2001-04-19 2003-10-14 Synthes (U.S.A.) Inflatable device and method for reducing fractures in bone and in treating the spine
US20030028251A1 (en) 2001-07-30 2003-02-06 Mathews Hallett H. Methods and devices for interbody spinal stabilization
US6793660B2 (en) 2001-08-20 2004-09-21 Synthes (U.S.A.) Threaded syringe for delivery of a bone substitute material
US20030050644A1 (en) 2001-09-11 2003-03-13 Boucher Ryan P. Systems and methods for accessing and treating diseased or fractured bone employing a guide wire
US6706069B2 (en) 2001-09-13 2004-03-16 J. Lee Berger Spinal grooved director with built in balloon
GB2382028B (en) 2001-11-19 2006-11-01 Aberdeen Orthopaedic Developme Intervertebral disc prosthesis
US6780191B2 (en) 2001-12-28 2004-08-24 Yacmur Llc Cannula system
US6736850B2 (en) * 2001-12-28 2004-05-18 Spinal Concepts, Inc. Vertebral pseudo arthrosis device and method
US6960215B2 (en) 2002-05-08 2005-11-01 Boston Scientific Scimed, Inc. Tactical detachable anatomic containment device and therapeutic treatment system
US7901407B2 (en) 2002-08-02 2011-03-08 Boston Scientific Scimed, Inc. Media delivery device for bone structures
US6932843B2 (en) * 2002-09-25 2005-08-23 Medicinelodge, Inc. Apparatus and method for the in-situ formation of a structural prosthesis
WO2004047689A1 (en) 2002-11-21 2004-06-10 Sdgi Holdings, Inc. Systems and techniques for intravertebral spinal stablization with expandable devices
US20040186471A1 (en) * 2002-12-07 2004-09-23 Sdgi Holdings, Inc. Method and apparatus for intervertebral disc expansion
TW554739U (en) 2002-12-18 2003-09-21 Guan-Gu Lin Flexible non-airtight medical filling device
TWI221091B (en) 2003-04-18 2004-09-21 A Spine Holding Group Corp Spine filling device
TWI235055B (en) 2003-05-21 2005-07-01 Guan-Gu Lin Filling device capable of removing animal tissues
TW587932B (en) * 2003-05-21 2004-05-21 Guan-Gu Lin Removable animal tissue filling device
ATE346558T1 (en) 2003-07-08 2006-12-15 Kwan-Ku Lin FLEXIBLE, EXPANDABLE AND AIR PERMEABLE IMPLANT FOR MEDICAL PURPOSES
ATE347322T1 (en) 2003-07-08 2006-12-15 A Spine Holding Group Corp FILLABLE IMPLANT AND SYSTEM FOR TREATING A DEFORMED OR PATHOLOGICALLY ALTERED SPINE
EP1663029A4 (en) 2003-09-03 2010-06-09 Kyphon Sarl Devices for creating voids in interior body regions and related methods
TW200511970A (en) 2003-09-29 2005-04-01 Kwan-Ku Lin A spine wrapping and filling apparatus
US7465318B2 (en) 2004-04-15 2008-12-16 Soteira, Inc. Cement-directing orthopedic implants
ATE375766T1 (en) 2004-04-22 2007-11-15 Kwan-Ku Lin EXTENDABLE DEVICE WITH FILLER FOR INTRODUCING MEDICINAL PRODUCTS INTO ANIMAL TISSUE
EP1588732B1 (en) 2004-04-22 2007-06-13 Kwan-Ku Lin Extractable filler for inserting medicine into animal tissue
US8142462B2 (en) 2004-05-28 2012-03-27 Cavitech, Llc Instruments and methods for reducing and stabilizing bone fractures
CN106963464B (en) 2004-07-30 2019-11-05 德普伊新特斯产品有限责任公司 Surgical set
JP2008511422A (en) 2004-09-02 2008-04-17 クロストゥリーズ・メディカル・インコーポレーテッド Device and method for distraction of spinal disc space
US7682378B2 (en) 2004-11-10 2010-03-23 Dfine, Inc. Bone treatment systems and methods for introducing an abrading structure to abrade bone
PE20060861A1 (en) 2005-01-07 2006-10-25 Celonova Biosciences Inc IMPLANTABLE THREE-DIMENSIONAL BONE SUPPORT
US7615052B2 (en) 2005-04-29 2009-11-10 Warsaw Orthopedic, Inc. Surgical instrument and method
KR20080047357A (en) 2005-07-07 2008-05-28 크로스트리스 메디칼, 인코포레이티드 Devices and methods for the treatment of bone fracture
EP1968505A4 (en) 2005-11-23 2011-12-28 Crosstrees Medical Inc Devices and methods for the treatment of bone fracture
US8961553B2 (en) 2007-09-14 2015-02-24 Crosstrees Medical, Inc. Material control device for inserting material into a targeted anatomical region

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5976186A (en) 1994-09-08 1999-11-02 Stryker Technologies Corporation Hydrogel intervertebral disc nucleus
US6602291B1 (en) 1999-04-05 2003-08-05 Raymedica, Inc. Prosthetic spinal disc nucleus having a shape change characteristic
US6508839B1 (en) 1999-08-18 2003-01-21 Intrinsic Orthopedics, Inc. Devices and methods of vertebral disc augmentation
US20050043688A1 (en) 2003-08-19 2005-02-24 Gremel Robert F. Apparatus for retaining concentric parts within one another

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
See also references of EP1793769A4

Cited By (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9113988B2 (en) 2003-05-21 2015-08-25 Crosstrees Medical, Inc. Method for inserting medicine into animal tissue
US9326806B2 (en) 2003-09-02 2016-05-03 Crosstrees Medical, Inc. Devices and methods for the treatment of bone fracture
US8623025B2 (en) 2006-12-15 2014-01-07 Gmedelaware 2 Llc Delivery apparatus and methods for vertebrostenting
US9237916B2 (en) 2006-12-15 2016-01-19 Gmedeleware 2 Llc Devices and methods for vertebrostenting
US9480485B2 (en) 2006-12-15 2016-11-01 Globus Medical, Inc. Devices and methods for vertebrostenting
US9687255B2 (en) 2008-06-17 2017-06-27 Globus Medical, Inc. Device and methods for fracture reduction
US10588646B2 (en) 2008-06-17 2020-03-17 Globus Medical, Inc. Devices and methods for fracture reduction
US9433404B2 (en) 2012-10-31 2016-09-06 Suture Concepts Inc. Method and apparatus for closing fissures in the annulus fibrosus
US9949734B2 (en) 2012-10-31 2018-04-24 Suture Concepts Inc. Method and apparatus for closing a fissure in the annulus of an intervertebral disc, and/or for effecting other anatomical repairs and/or fixations
US10786235B2 (en) 2012-10-31 2020-09-29 Anchor Innovation Medical, Inc. Method and apparatus for closing a fissure in the annulus of an intervertebral disc, and/or for effecting other anatomical repairs and/or fixations
US10863979B2 (en) 2012-10-31 2020-12-15 Anchor Innovation Medical, Inc. Method and apparatus for closing a fissure in the annulus of an intervertebral disc, and/or for effecting other anatomical repairs and/or fixations

Also Published As

Publication number Publication date
US20080097511A1 (en) 2008-04-24
CN101257864A (en) 2008-09-03
WO2006028986A3 (en) 2006-06-01
JP2008511422A (en) 2008-04-17
US7993345B2 (en) 2011-08-09
US7749230B2 (en) 2010-07-06
US20110288530A1 (en) 2011-11-24
US20110004312A1 (en) 2011-01-06
EP1793769A4 (en) 2009-06-24
EP1793769A2 (en) 2007-06-13

Similar Documents

Publication Publication Date Title
US7749230B2 (en) Device and method for distraction of the spinal disc space
US8007500B2 (en) Extractable filler for inserting medicine into animal tissue
US7993343B2 (en) Extractable filler for inserting medicine into vertebral body
US9113988B2 (en) Method for inserting medicine into animal tissue
EP2010267B1 (en) Instrumentation kit for delivering viscous bone filler material
KR100948082B1 (en) Tool and Technique for Continually Delivering an Orthopaedic Paste
TWI503097B (en) Bone fixation device
US20110288522A1 (en) Apparatus and methods for detaching an expandable member from a medical device
US20040210297A1 (en) Filling device and system for treating a deformed or diseased spine
JP2004329859A (en) Apparatus for fixing tissue to bone
TWI528938B (en) Bone fixation device
EP1588674B1 (en) Extractable device with filler for inserting medicine into animal tissue
EP1588732B1 (en) Extractable filler for inserting medicine into animal tissue
TW202106254A (en) Vertebral implant including a filling member, a hollow tube and a medical filler

Legal Events

Date Code Title Description
WWE Wipo information: entry into national phase

Ref document number: 200580037847.6

Country of ref document: CN

AK Designated states

Kind code of ref document: A2

Designated state(s): AE AG AL AM AT AU AZ BA BB BG BR BW BY BZ CA CH CN CO CR CU CZ DE DK DM DZ EC EE EG ES FI GB GD GE GH GM HR HU ID IL IN IS JP KE KG KM KP KR KZ LC LK LR LS LT LU LV MA MD MG MK MN MW MX MZ NA NG NI NO NZ OM PG PH PL PT RO RU SC SD SE SG SK SL SM SY TJ TM TN TR TT TZ UA UG US UZ VC VN YU ZA ZM ZW

AL Designated countries for regional patents

Kind code of ref document: A2

Designated state(s): BW GH GM KE LS MW MZ NA SD SL SZ TZ UG ZM ZW AM AZ BY KG KZ MD RU TJ TM AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IS IT LT LU LV MC NL PL PT RO SE SI SK TR BF BJ CF CG CI CM GA GN GQ GW ML MR NE SN TD TG

WWE Wipo information: entry into national phase

Ref document number: 11574562

Country of ref document: US

Ref document number: 2007530405

Country of ref document: JP

NENP Non-entry into the national phase

Ref country code: DE

WWE Wipo information: entry into national phase

Ref document number: 2005794205

Country of ref document: EP

WWP Wipo information: published in national office

Ref document number: 2005794205

Country of ref document: EP