WO2006021709A3 - Particule solide anhydre contenant une composition lipidique et composition pharmaceutique contenant lesdites particules - Google Patents

Particule solide anhydre contenant une composition lipidique et composition pharmaceutique contenant lesdites particules Download PDF

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Publication number
WO2006021709A3
WO2006021709A3 PCT/FR2005/050599 FR2005050599W WO2006021709A3 WO 2006021709 A3 WO2006021709 A3 WO 2006021709A3 FR 2005050599 W FR2005050599 W FR 2005050599W WO 2006021709 A3 WO2006021709 A3 WO 2006021709A3
Authority
WO
WIPO (PCT)
Prior art keywords
particles
solid particle
lipid composition
pharmaceutical composition
anhydrous solid
Prior art date
Application number
PCT/FR2005/050599
Other languages
English (en)
Other versions
WO2006021709A2 (fr
Inventor
Delphine Marchaud
Pascale Blachez
Original Assignee
Gattefosse Holding
Delphine Marchaud
Pascale Blachez
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Gattefosse Holding, Delphine Marchaud, Pascale Blachez filed Critical Gattefosse Holding
Publication of WO2006021709A2 publication Critical patent/WO2006021709A2/fr
Publication of WO2006021709A3 publication Critical patent/WO2006021709A3/fr

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1611—Inorganic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1617—Organic compounds, e.g. phospholipids, fats
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2072—Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
    • A61K9/2077—Tablets comprising drug-containing microparticles in a substantial amount of supporting matrix; Multiparticulate tablets
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2009—Inorganic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
    • A61K9/2054—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose

Landscapes

  • Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Inorganic Chemistry (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

Particule anhydre constituée d'un support sur lequel est appliqué un mélange constitué d'au moins un principe actif et d'une composition lipidique auto-émulsionnable, caractérisée en ce que la composition lipidique contient du macrogolglycéride caprylocaprique.
PCT/FR2005/050599 2004-08-05 2005-07-20 Particule solide anhydre contenant une composition lipidique et composition pharmaceutique contenant lesdites particules WO2006021709A2 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR0451792 2004-08-05
FR0451792A FR2873923B1 (fr) 2004-08-05 2004-08-05 Particule solide anhydre contenant une composition lipidique liquide et composition pharmaceutique contenant lesdites particules

Publications (2)

Publication Number Publication Date
WO2006021709A2 WO2006021709A2 (fr) 2006-03-02
WO2006021709A3 true WO2006021709A3 (fr) 2006-10-12

Family

ID=34950228

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/FR2005/050599 WO2006021709A2 (fr) 2004-08-05 2005-07-20 Particule solide anhydre contenant une composition lipidique et composition pharmaceutique contenant lesdites particules

Country Status (2)

Country Link
FR (1) FR2873923B1 (fr)
WO (1) WO2006021709A2 (fr)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2011120530A1 (fr) * 2010-03-31 2011-10-06 Lifecycle Phama A/S Comprimés poreux en tant que véhicules pour formulations liquides

Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2000059475A1 (fr) * 1999-04-06 2000-10-12 Lipocine, Inc. Compositions et procedes d'administration amelioree d'agents therapeutiques hydrophobes ionisables
WO2001032142A1 (fr) * 1999-11-02 2001-05-10 Cipla Limited Formulation de cyclosporine
WO2003011207A2 (fr) * 2001-07-27 2003-02-13 Gattefosse Holding Composition pharmaceutique a usage oral comprenant un principe actif susceptible de subir un important effet de premier passage intestinal
WO2004000273A1 (fr) * 2002-06-25 2003-12-31 Nicox S.A. Formes pharmaceutiques orales de medicaments liquides a biodisponibilite amelioree
WO2004045586A1 (fr) * 2002-11-15 2004-06-03 Bioserentach Co., Ltd. Preparation solidifiee visant a favoriser l'absorption medicamenteuse

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0448091B1 (fr) * 1990-03-23 1998-08-05 The Green Cross Corporation Composition pharmaceutique comportant un médicament peu soluble dans l'eau
KR0146671B1 (ko) * 1994-02-25 1998-08-17 김충환 사이클로스포린-함유 분말 조성물
AU1881600A (en) * 1998-12-23 2000-07-31 Alza Corporation Dosage forms comprising porous particles

Patent Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2000059475A1 (fr) * 1999-04-06 2000-10-12 Lipocine, Inc. Compositions et procedes d'administration amelioree d'agents therapeutiques hydrophobes ionisables
WO2001032142A1 (fr) * 1999-11-02 2001-05-10 Cipla Limited Formulation de cyclosporine
WO2003011207A2 (fr) * 2001-07-27 2003-02-13 Gattefosse Holding Composition pharmaceutique a usage oral comprenant un principe actif susceptible de subir un important effet de premier passage intestinal
WO2004000273A1 (fr) * 2002-06-25 2003-12-31 Nicox S.A. Formes pharmaceutiques orales de medicaments liquides a biodisponibilite amelioree
WO2004045586A1 (fr) * 2002-11-15 2004-06-03 Bioserentach Co., Ltd. Preparation solidifiee visant a favoriser l'absorption medicamenteuse

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
DATABASE CA [online] CHEMICAL ABSTRACTS SERVICE, COLUMBUS, OHIO, US; TAKADA, KANJI: "Solidified preparation aiming at promoting drug absorption", XP002394795, retrieved from STN Database accession no. 140:429052 *
ITO Y ET AL: "Oral solid gentamicin preparation using emulsifier and adsorbent", JOURNAL OF CONTROLLED RELEASE, ELSEVIER, AMSTERDAM, NL, vol. 105, no. 1-2, 20 June 2005 (2005-06-20), pages 23 - 31, XP004933078, ISSN: 0168-3659 *

Also Published As

Publication number Publication date
FR2873923A1 (fr) 2006-02-10
FR2873923B1 (fr) 2007-01-12
WO2006021709A2 (fr) 2006-03-02

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