WO2006014793A1 - Dispositif implantable comprenant un reservoir a liberation commandee de medicament et procede de fabrication de celui-ci - Google Patents

Dispositif implantable comprenant un reservoir a liberation commandee de medicament et procede de fabrication de celui-ci Download PDF

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Publication number
WO2006014793A1
WO2006014793A1 PCT/US2005/025998 US2005025998W WO2006014793A1 WO 2006014793 A1 WO2006014793 A1 WO 2006014793A1 US 2005025998 W US2005025998 W US 2005025998W WO 2006014793 A1 WO2006014793 A1 WO 2006014793A1
Authority
WO
WIPO (PCT)
Prior art keywords
medication
reservoir
head
tip
providing
Prior art date
Application number
PCT/US2005/025998
Other languages
English (en)
Inventor
Anthony D. Prescott
Original Assignee
Clarity Corporation
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US10/899,416 external-priority patent/US7117870B2/en
Priority claimed from US10/899,417 external-priority patent/US20060020253A1/en
Application filed by Clarity Corporation filed Critical Clarity Corporation
Priority to AU2005269599A priority Critical patent/AU2005269599A1/en
Priority to EP05773660A priority patent/EP1778198A1/fr
Priority to CA002573892A priority patent/CA2573892A1/fr
Publication of WO2006014793A1 publication Critical patent/WO2006014793A1/fr

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A61K9/0024—Solid, semi-solid or solidifying implants, which are implanted or injected in body tissue
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F9/00—Methods or devices for treatment of the eyes; Devices for putting-in contact lenses; Devices to correct squinting; Apparatus to guide the blind; Protective devices for the eyes, carried on the body or in the hand
    • A61F9/0008—Introducing ophthalmic products into the ocular cavity or retaining products therein
    • A61F9/0017—Introducing ophthalmic products into the ocular cavity or retaining products therein implantable in, or in contact with, the eye, e.g. ocular inserts
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F9/00—Methods or devices for treatment of the eyes; Devices for putting-in contact lenses; Devices to correct squinting; Apparatus to guide the blind; Protective devices for the eyes, carried on the body or in the hand
    • A61F9/007—Methods or devices for eye surgery
    • A61F9/00772—Apparatus for restoration of tear ducts
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0048—Eye, e.g. artificial tears
    • A61K9/0051—Ocular inserts, ocular implants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2250/00—Special features of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof
    • A61F2250/0014—Special features of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof having different values of a given property or geometrical feature, e.g. mechanical property or material property, at different locations within the same prosthesis
    • A61F2250/0023—Special features of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof having different values of a given property or geometrical feature, e.g. mechanical property or material property, at different locations within the same prosthesis differing in porosity

Abstract

L'invention concerne un dispositif implantable (10) comprenant un corps (12) définissant un réservoir (14) et une tête (24) placée au niveau d'une extrémité du corps (12) et fermant le réservoir. Le corps (12) est conçu dans un matériau imperméable au médicament alors que la tête (24) est conçue dans un matériau perméable conçu pour libérer le médicament du réservoir dans un site d'implant à une vitesse pouvant être déterminée. Selon une fabrication, le corps (12) du dispositif est moulé et comprend un trou au niveau d'une extrémité en pointe; la tête (24) est moulée sur le corps (12); le médicament est injecté dans le dispositif par le biais du trou de l'extrémité en pointe; et l'extrémité en pointe est scellée. La partie du dispositif au niveau de laquelle le médicament est libéré est fabriquée de manière précise afin de commander la libération du médicament et le réservoir est rempli, puis fermé à distance de la zone de perméabilité au médicament.
PCT/US2005/025998 2004-07-26 2005-07-21 Dispositif implantable comprenant un reservoir a liberation commandee de medicament et procede de fabrication de celui-ci WO2006014793A1 (fr)

Priority Applications (3)

Application Number Priority Date Filing Date Title
AU2005269599A AU2005269599A1 (en) 2004-07-26 2005-07-21 Implantable device having reservoir with controlled release of medication and method of manufacturing the same
EP05773660A EP1778198A1 (fr) 2004-07-26 2005-07-21 Dispositif implantable comprenant un reservoir a liberation commandee de medicament et procede de fabrication de celui-ci
CA002573892A CA2573892A1 (fr) 2004-07-26 2005-07-21 Dispositif implantable comprenant un reservoir a liberation commandee de medicament et procede de fabrication de celui-ci

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US10/899,416 US7117870B2 (en) 2004-07-26 2004-07-26 Lacrimal insert having reservoir with controlled release of medication and method of manufacturing the same
US10/899,416 2004-07-26
US10/899,417 US20060020253A1 (en) 2004-07-26 2004-07-26 Implantable device having reservoir with controlled release of medication and method of manufacturing the same
US10/899,417 2004-07-26

Publications (1)

Publication Number Publication Date
WO2006014793A1 true WO2006014793A1 (fr) 2006-02-09

Family

ID=35787435

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2005/025998 WO2006014793A1 (fr) 2004-07-26 2005-07-21 Dispositif implantable comprenant un reservoir a liberation commandee de medicament et procede de fabrication de celui-ci

Country Status (4)

Country Link
EP (1) EP1778198A1 (fr)
AU (1) AU2005269599A1 (fr)
CA (1) CA2573892A1 (fr)
WO (1) WO2006014793A1 (fr)

Cited By (25)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2007149832A2 (fr) * 2006-06-21 2007-12-27 Johnson & Johnson Vision Care, Inc. Bouchons ponctuels pour livraison d'agents actifs
JP2008006287A (ja) * 2006-06-21 2008-01-17 Johnson & Johnson Vision Care Inc 活性剤の投与のための涙点プラグ
WO2007149773A3 (fr) * 2006-06-21 2008-02-14 Johnson & Johnson Vision Care Bouchons ponctuels pour la livraison d'agents actifs
US7887508B2 (en) 2006-03-14 2011-02-15 The University Of Southern California MEMS device and method for delivery of therapeutic agents
WO2011025766A1 (fr) * 2009-08-31 2011-03-03 Johnson & Johnson Vision Care, Inc. Libération pulsatile de médicaments à partir d’un bouchon méatique
WO2011066479A1 (fr) * 2009-11-27 2011-06-03 Qlt Plug Delivery, Inc. Implants lacrimaux contenant un noyau de médicament fendu et insérable
US7998497B2 (en) 2006-03-31 2011-08-16 Qlt Inc. Nasolacrimal drainage system implants for drug therapy
US8231609B2 (en) 2008-05-08 2012-07-31 Minipumps, Llc Drug-delivery pumps and methods of manufacture
CN101505696B (zh) * 2006-06-21 2012-11-14 庄臣及庄臣视力保护公司 用于递送活性试剂的泪点塞
US8348897B2 (en) 2008-05-08 2013-01-08 Minipumps, Llc Implantable drug-delivery devices, and apparatus and methods for filling the devices
US8628792B2 (en) 2007-09-07 2014-01-14 Mati Therapeutics, Inc. Drug cores for sustained release of therapeutic agents
US9180050B2 (en) 2004-08-17 2015-11-10 California Institute Of Technology Implantable intraocular pressure drain
US9199035B2 (en) 2008-05-08 2015-12-01 Minipumps, Llc. Drug-delivery pumps with dynamic, adaptive control
US9271866B2 (en) 2007-12-20 2016-03-01 University Of Southern California Apparatus and methods for delivering therapeutic agents
US9333297B2 (en) 2008-05-08 2016-05-10 Minipumps, Llc Drug-delivery pump with intelligent control
US9603997B2 (en) 2011-03-14 2017-03-28 Minipumps, Llc Implantable drug pumps and refill devices therefor
US9610271B2 (en) 2011-08-29 2017-04-04 Mati Therapeutics Inc. Sustained release delivery of active agents to treat glaucoma and ocular hypertension
US9623174B2 (en) 2008-05-08 2017-04-18 Minipumps, Llc Implantable pumps and cannulas therefor
US9901687B2 (en) 2008-01-03 2018-02-27 University Of Southern California Implantable drug-delivery devices, and apparatus and methods for refilling the devices
US9919099B2 (en) 2011-03-14 2018-03-20 Minipumps, Llc Implantable drug pumps and refill devices therefor
US9974685B2 (en) 2011-08-29 2018-05-22 Mati Therapeutics Drug delivery system and methods of treating open angle glaucoma and ocular hypertension
WO2018217662A1 (fr) * 2017-05-22 2018-11-29 California Institute Of Technology Dispositif de transport de petite molécule doté d'une charge anti-condensation pour administration de médicament ou élimination de déchet
US10286146B2 (en) 2011-03-14 2019-05-14 Minipumps, Llc Implantable drug pumps and refill devices therefor
US10610407B2 (en) 2004-07-02 2020-04-07 Mati Therapeutics Inc. Treatment medium delivery device and methods for delivery of such treatment mediums to the eye using such delivery device
US11141312B2 (en) 2007-09-07 2021-10-12 Mati Therapeutics Inc. Lacrimal implant detection

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3993071A (en) * 1971-09-09 1976-11-23 Alza Corporation Bioerodible ocular device
US5378475A (en) * 1991-02-21 1995-01-03 University Of Kentucky Research Foundation Sustained release drug delivery devices
US6196993B1 (en) * 1998-04-20 2001-03-06 Eyelab Group, Llc Ophthalmic insert and method for sustained release of medication to the eye

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3993071A (en) * 1971-09-09 1976-11-23 Alza Corporation Bioerodible ocular device
US5378475A (en) * 1991-02-21 1995-01-03 University Of Kentucky Research Foundation Sustained release drug delivery devices
US6196993B1 (en) * 1998-04-20 2001-03-06 Eyelab Group, Llc Ophthalmic insert and method for sustained release of medication to the eye

Cited By (62)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US10610407B2 (en) 2004-07-02 2020-04-07 Mati Therapeutics Inc. Treatment medium delivery device and methods for delivery of such treatment mediums to the eye using such delivery device
US9180050B2 (en) 2004-08-17 2015-11-10 California Institute Of Technology Implantable intraocular pressure drain
US7887508B2 (en) 2006-03-14 2011-02-15 The University Of Southern California MEMS device and method for delivery of therapeutic agents
US9693894B2 (en) 2006-03-14 2017-07-04 The University Of Southern California MEMS device and method for delivery of therapeutic agents
US8764708B2 (en) 2006-03-14 2014-07-01 The University Of Southern California MEMS device and method for delivery of therapeutic agents
US8308686B2 (en) 2006-03-14 2012-11-13 The University Of Southern California MEMS device and method for delivery of therapeutic agents
US8795711B2 (en) * 2006-03-31 2014-08-05 Mati Therapeutics Inc. Drug delivery methods, structures, and compositions for nasolacrimal system
US10383817B2 (en) 2006-03-31 2019-08-20 Mati Therapeutics Inc. Nasolacrimal drainage system implants for drug therapy
US9168222B2 (en) 2006-03-31 2015-10-27 Mati Therapeutics Inc. Nasolacrimal drainage system implants for drug therapy
US7998497B2 (en) 2006-03-31 2011-08-16 Qlt Inc. Nasolacrimal drainage system implants for drug therapy
US9610194B2 (en) 2006-03-31 2017-04-04 Mati Therapeutics Inc. Drug delivery methods, structures, and compositions for nasolacrimal system
US10874606B2 (en) 2006-03-31 2020-12-29 Mati Therapeutics Inc. Nasolacrimal drainage system implants for drug therapy
US9849082B2 (en) 2006-03-31 2017-12-26 Mati Therapeutics Inc. Nasolacrimal drainage system implants for drug therapy
US8691265B2 (en) 2006-03-31 2014-04-08 Mati Therapeutics, Inc. Drug delivery methods, structures, and compositions for nasolacrimal system
US11406592B2 (en) 2006-03-31 2022-08-09 Mati Therapeutics Inc. Drug delivery methods, structures, and compositions for nasolacrimal system
US10300014B2 (en) 2006-03-31 2019-05-28 Mati Therapeutics Inc. Nasolacrimal drainage system implants for drug therapy
CN101505696B (zh) * 2006-06-21 2012-11-14 庄臣及庄臣视力保护公司 用于递送活性试剂的泪点塞
RU2452438C2 (ru) * 2006-06-21 2012-06-10 Джонсон Энд Джонсон Вижн Кэа, Инк. Втулки слезных точек для доставки активных агентов
AU2007261037B2 (en) * 2006-06-21 2013-10-10 Johnson & Johnson Vision Care, Inc. Punctal plugs for the delivery of active agents
AU2007261070B2 (en) * 2006-06-21 2013-10-17 Johnson & Johnson Vision Care, Inc. Punctal plugs for the delivery of active agents
US9474645B2 (en) 2006-06-21 2016-10-25 Johnson & Johnson Vision Care, Inc. Punctal plugs for the delivery of active agents
JP2009540945A (ja) * 2006-06-21 2009-11-26 ジョンソン・アンド・ジョンソン・ビジョン・ケア・インコーポレイテッド 活性剤送達用の涙点プラグ
KR101388440B1 (ko) * 2006-06-21 2014-04-23 존슨 앤드 존슨 비젼 케어, 인코포레이티드 활성제 전달용 눈물점 마개
WO2007149832A3 (fr) * 2006-06-21 2008-10-02 Johnson & Johnson Vision Care Bouchons ponctuels pour livraison d'agents actifs
JP2008006287A (ja) * 2006-06-21 2008-01-17 Johnson & Johnson Vision Care Inc 活性剤の投与のための涙点プラグ
US9173773B2 (en) 2006-06-21 2015-11-03 Johnson & Johnson Vision Care, Inc. Punctal plugs for the delivery of active agents
WO2007149832A2 (fr) * 2006-06-21 2007-12-27 Johnson & Johnson Vision Care, Inc. Bouchons ponctuels pour livraison d'agents actifs
JP2009540951A (ja) * 2006-06-21 2009-11-26 ジョンソン・アンド・ジョンソン・ビジョン・ケア・インコーポレイテッド 活性剤送達用の涙点プラグ
WO2007149773A3 (fr) * 2006-06-21 2008-02-14 Johnson & Johnson Vision Care Bouchons ponctuels pour la livraison d'agents actifs
US11141312B2 (en) 2007-09-07 2021-10-12 Mati Therapeutics Inc. Lacrimal implant detection
US8628792B2 (en) 2007-09-07 2014-01-14 Mati Therapeutics, Inc. Drug cores for sustained release of therapeutic agents
US10117774B2 (en) 2007-12-20 2018-11-06 University Of Southern California Apparatus and methods for delivering therapeutic agents
US9308124B2 (en) 2007-12-20 2016-04-12 University Of Southern California Apparatus and methods for delivering therapeutic agents
US9271866B2 (en) 2007-12-20 2016-03-01 University Of Southern California Apparatus and methods for delivering therapeutic agents
US9901687B2 (en) 2008-01-03 2018-02-27 University Of Southern California Implantable drug-delivery devices, and apparatus and methods for refilling the devices
US8348897B2 (en) 2008-05-08 2013-01-08 Minipumps, Llc Implantable drug-delivery devices, and apparatus and methods for filling the devices
US8529538B2 (en) 2008-05-08 2013-09-10 Minipumps, Llc Drug-delivery pumps and methods of manufacture
US9333297B2 (en) 2008-05-08 2016-05-10 Minipumps, Llc Drug-delivery pump with intelligent control
US9199035B2 (en) 2008-05-08 2015-12-01 Minipumps, Llc. Drug-delivery pumps with dynamic, adaptive control
US8231609B2 (en) 2008-05-08 2012-07-31 Minipumps, Llc Drug-delivery pumps and methods of manufacture
US9162024B2 (en) 2008-05-08 2015-10-20 Minipumps, Llc Drug-delivery pumps and methods of manufacture
US8231608B2 (en) 2008-05-08 2012-07-31 Minipumps, Llc Drug-delivery pumps and methods of manufacture
US9623174B2 (en) 2008-05-08 2017-04-18 Minipumps, Llc Implantable pumps and cannulas therefor
US8486278B2 (en) 2008-05-08 2013-07-16 Minipumps, Llc Drug-delivery pumps and methods of manufacture
US9107995B2 (en) 2008-05-08 2015-08-18 Minipumps, Llc Drug-delivery pumps and methods of manufacture
US9849238B2 (en) 2008-05-08 2017-12-26 Minipumps, Llc Drug-delivery pump with intelligent control
US9861525B2 (en) 2008-05-08 2018-01-09 Minipumps, Llc Drug-delivery pumps and methods of manufacture
US9050407B2 (en) 2008-05-08 2015-06-09 Minipumps, Llc Implantable drug-delivery devices, and apparatus and methods for filling the devices
US9283322B2 (en) 2008-05-08 2016-03-15 Minipumps, Llc Drug-delivery pump with dynamic, adaptive control
US9987417B2 (en) 2008-05-08 2018-06-05 Minipumps, Llc Implantable drug-delivery devices, and apparatus and methods for filling the devices
US8808257B2 (en) 2009-08-31 2014-08-19 Johnson & Johnson Vision Care, Inc. Methods and apparatus for pulsatile release of medicaments from a punctal plug
US9125715B2 (en) 2009-08-31 2015-09-08 Johnson & Johnson Vision Care, Inc. Pulsatile release of medicaments from a punctal plug
WO2011025766A1 (fr) * 2009-08-31 2011-03-03 Johnson & Johnson Vision Care, Inc. Libération pulsatile de médicaments à partir d’un bouchon méatique
WO2011066479A1 (fr) * 2009-11-27 2011-06-03 Qlt Plug Delivery, Inc. Implants lacrimaux contenant un noyau de médicament fendu et insérable
US10286146B2 (en) 2011-03-14 2019-05-14 Minipumps, Llc Implantable drug pumps and refill devices therefor
US9919099B2 (en) 2011-03-14 2018-03-20 Minipumps, Llc Implantable drug pumps and refill devices therefor
US9603997B2 (en) 2011-03-14 2017-03-28 Minipumps, Llc Implantable drug pumps and refill devices therefor
US9974685B2 (en) 2011-08-29 2018-05-22 Mati Therapeutics Drug delivery system and methods of treating open angle glaucoma and ocular hypertension
US9610271B2 (en) 2011-08-29 2017-04-04 Mati Therapeutics Inc. Sustained release delivery of active agents to treat glaucoma and ocular hypertension
US10632012B2 (en) 2011-08-29 2020-04-28 Mati Therapeutics Inc. Sustained release delivery of active agents to treat glaucoma and ocular hypertension
WO2018217662A1 (fr) * 2017-05-22 2018-11-29 California Institute Of Technology Dispositif de transport de petite molécule doté d'une charge anti-condensation pour administration de médicament ou élimination de déchet
US10492945B2 (en) 2017-05-22 2019-12-03 California Institute Of Technology Small molecule transport device with anti-condensation filler for drug delivery or waste removal

Also Published As

Publication number Publication date
EP1778198A1 (fr) 2007-05-02
CA2573892A1 (fr) 2006-02-09
AU2005269599A1 (en) 2006-02-09

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