WO2006012779A8 - Wikstroemia indeca extract their production and use in the production of anti-inflammatory pharmaceutical - Google Patents

Wikstroemia indeca extract their production and use in the production of anti-inflammatory pharmaceutical

Info

Publication number
WO2006012779A8
WO2006012779A8 PCT/CN2004/000907 CN2004000907W WO2006012779A8 WO 2006012779 A8 WO2006012779 A8 WO 2006012779A8 CN 2004000907 W CN2004000907 W CN 2004000907W WO 2006012779 A8 WO2006012779 A8 WO 2006012779A8
Authority
WO
WIPO (PCT)
Prior art keywords
production
indeca
wikstroemia
extract
inflammatory pharmaceutical
Prior art date
Application number
PCT/CN2004/000907
Other languages
French (fr)
Chinese (zh)
Other versions
WO2006012779A1 (en
Inventor
Liyan Wang
Susumu Kitanaka
Original Assignee
Univ Nihon
Liyan Wang
Susumu Kitanaka
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Nihon, Liyan Wang, Susumu Kitanaka filed Critical Univ Nihon
Priority to CN2004800437624A priority Critical patent/CN101014560B/en
Priority to PCT/CN2004/000907 priority patent/WO2006012779A1/en
Publication of WO2006012779A1 publication Critical patent/WO2006012779A1/en
Publication of WO2006012779A8 publication Critical patent/WO2006012779A8/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/83—Thymelaeaceae (Mezereum family), e.g. leatherwood or false ohelo
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23K—FODDER
    • A23K20/00—Accessory food factors for animal feeding-stuffs
    • A23K20/10—Organic substances
    • A23K20/105—Aliphatic or alicyclic compounds
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
    • A23L33/105—Plant extracts, their artificial duplicates or their derivatives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/12—Ketones
    • A61K31/122—Ketones having the oxygen directly attached to a ring, e.g. quinones, vitamin K1, anthralin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/12—Drugs for disorders of the urinary system of the kidneys
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A61P27/06—Antiglaucoma agents or miotics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/78—Separation; Purification; Stabilisation; Use of additives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C49/00—Ketones; Ketenes; Dimeric ketenes; Ketonic chelates
    • C07C49/587—Unsaturated compounds containing a keto groups being part of a ring
    • C07C49/703—Unsaturated compounds containing a keto groups being part of a ring containing hydroxy groups
    • C07C49/723—Unsaturated compounds containing a keto groups being part of a ring containing hydroxy groups polycyclic
    • C07C49/727—Unsaturated compounds containing a keto groups being part of a ring containing hydroxy groups polycyclic a keto group being part of a condensed ring system
    • C07C49/733—Unsaturated compounds containing a keto groups being part of a ring containing hydroxy groups polycyclic a keto group being part of a condensed ring system having two rings

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Natural Medicines & Medicinal Plants (AREA)
  • Immunology (AREA)
  • Polymers & Plastics (AREA)
  • Mycology (AREA)
  • Rheumatology (AREA)
  • Ophthalmology & Optometry (AREA)
  • Botany (AREA)
  • Epidemiology (AREA)
  • Food Science & Technology (AREA)
  • Animal Husbandry (AREA)
  • Nutrition Science (AREA)
  • Pain & Pain Management (AREA)
  • Urology & Nephrology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Dermatology (AREA)
  • Zoology (AREA)
  • Transplantation (AREA)
  • Alternative & Traditional Medicine (AREA)
  • Biotechnology (AREA)
  • Medical Informatics (AREA)
  • Microbiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines Containing Plant Substances (AREA)

Abstract

The invention relates to extracts from wilstroemia indeca C.A.Mey, the preparation method and pharmaceutical uses thereof, the formula (1) of the extracted active compound.
PCT/CN2004/000907 2004-08-06 2004-08-06 Wikstroemia indeca extract their production and use in the production of anti-inflammatory pharmaceutical WO2006012779A1 (en)

Priority Applications (2)

Application Number Priority Date Filing Date Title
CN2004800437624A CN101014560B (en) 2004-08-06 2004-08-06 Wikstroemia indeca extract, their production and use in the production of anti-inflammatory pharmaceutical
PCT/CN2004/000907 WO2006012779A1 (en) 2004-08-06 2004-08-06 Wikstroemia indeca extract their production and use in the production of anti-inflammatory pharmaceutical

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PCT/CN2004/000907 WO2006012779A1 (en) 2004-08-06 2004-08-06 Wikstroemia indeca extract their production and use in the production of anti-inflammatory pharmaceutical

Publications (2)

Publication Number Publication Date
WO2006012779A1 WO2006012779A1 (en) 2006-02-09
WO2006012779A8 true WO2006012779A8 (en) 2007-04-19

Family

ID=35786866

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/CN2004/000907 WO2006012779A1 (en) 2004-08-06 2004-08-06 Wikstroemia indeca extract their production and use in the production of anti-inflammatory pharmaceutical

Country Status (2)

Country Link
CN (1) CN101014560B (en)
WO (1) WO2006012779A1 (en)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN100463906C (en) * 2007-03-07 2009-02-25 哈尔滨医科大学附属第二医院 Extraction method for extraction and pharmaceutical containing the same
CN101601666B (en) * 2009-07-10 2011-05-25 暨南大学 Radix wikstroemae extractive and preparation method and application thereof
CN102344454B (en) * 2011-08-01 2013-11-06 广东药学院 Wikstroemia indica (L.) C.A.Mey extract as well as preparation method and application thereof
CN102311415B (en) * 2011-09-29 2013-06-26 广东药学院 Method for extracting daphnoretin from wikstroemia indica
CN105315147A (en) * 2014-08-03 2016-02-10 江苏康缘药业股份有限公司 Guaiane-type sesquiterpenoids compound, and preparation method and application thereof

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1181832C (en) * 1998-10-23 2004-12-29 深圳中药及天然药物研究中心 Preparation of AIDS resisting medicine from indian stringbush root extract

Also Published As

Publication number Publication date
WO2006012779A1 (en) 2006-02-09
CN101014560B (en) 2010-04-28
CN101014560A (en) 2007-08-08

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