WO2005123762B1 - Codon-optimized HPV16 li for salmonella vaccine strains against human papillomavirus type 16 - Google Patents
Codon-optimized HPV16 li for salmonella vaccine strains against human papillomavirus type 16Info
- Publication number
- WO2005123762B1 WO2005123762B1 PCT/IB2005/001725 IB2005001725W WO2005123762B1 WO 2005123762 B1 WO2005123762 B1 WO 2005123762B1 IB 2005001725 W IB2005001725 W IB 2005001725W WO 2005123762 B1 WO2005123762 B1 WO 2005123762B1
- Authority
- WO
- WIPO (PCT)
- Prior art keywords
- hpv
- prokaryotic microorganism
- salmonella enterica
- recombinant
- salmonella
- Prior art date
Links
Classifications
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/12—Viral antigens
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N7/00—Viruses; Bacteriophages; Compositions thereof; Preparation or purification thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
- A61K2039/52—Bacterial cells; Fungal cells; Protozoal cells
- A61K2039/523—Bacterial cells; Fungal cells; Protozoal cells expressing foreign proteins
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
- A61K2039/525—Virus
- A61K2039/5258—Virus-like particles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/54—Medicinal preparations containing antigens or antibodies characterised by the route of administration
- A61K2039/541—Mucosal route
- A61K2039/542—Mucosal route oral/gastrointestinal
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/54—Medicinal preparations containing antigens or antibodies characterised by the route of administration
- A61K2039/541—Mucosal route
- A61K2039/543—Mucosal route intranasal
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
- C12N2710/00011—Details
- C12N2710/20011—Papillomaviridae
- C12N2710/20022—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
- C12N2710/00011—Details
- C12N2710/20011—Papillomaviridae
- C12N2710/20023—Virus like particles [VLP]
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
- C12N2710/00011—Details
- C12N2710/20011—Papillomaviridae
- C12N2710/20034—Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein
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- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
Abstract
Claims
Priority Applications (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CN2005800278872A CN101115766B (en) | 2004-06-18 | 2005-06-20 | Codon-optimized HPV16LI for salmonella vaccine strains against human papillomavirus type 16 |
JP2007516066A JP4769247B2 (en) | 2004-06-18 | 2005-06-20 | Codon optimized HPV16L1 for Salmonella vaccine strain against human papillomavirus type 16 |
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CH2004000373 | 2004-06-18 | ||
CHPCT/CH2004/000373 | 2004-06-18 |
Publications (3)
Publication Number | Publication Date |
---|---|
WO2005123762A2 WO2005123762A2 (en) | 2005-12-29 |
WO2005123762A3 WO2005123762A3 (en) | 2006-04-27 |
WO2005123762B1 true WO2005123762B1 (en) | 2006-06-08 |
Family
ID=35510322
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PCT/IB2005/001725 WO2005123762A2 (en) | 2004-06-18 | 2005-06-20 | Codon-optimized hpv16 li for salmonella vaccine strains against human papillomavirus type 16 |
Country Status (3)
Country | Link |
---|---|
JP (1) | JP4769247B2 (en) |
CN (1) | CN101115766B (en) |
WO (1) | WO2005123762A2 (en) |
Families Citing this family (9)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP1887084A1 (en) * | 2006-08-10 | 2008-02-13 | International Investment and Patents SA | Plasmids with immunological action |
CN100532548C (en) * | 2007-02-14 | 2009-08-26 | 马润林 | Method of increasing yield of human papilloma virus L1 albumen pronucleus expression |
CN102178944A (en) * | 2010-09-17 | 2011-09-14 | 大连雅立峰生物制药有限公司 | Expression and application of human papilloma viruses type 16 and 18 L1 proteins in inset cells |
SG11201508521SA (en) | 2013-04-25 | 2015-11-27 | Vaximm Ag | Salmonella-based vectors for cancer immunotherapy targeting wilms' tumor gene wt1 |
EP2801364A1 (en) * | 2013-05-07 | 2014-11-12 | Centre Hospitalier Universitaire Vaudois (CHUV) | Salmonella strain for use in the treatment and/or prevention of cancer |
CN112280792B (en) * | 2013-09-29 | 2022-06-24 | 上海泽润生物科技有限公司 | Human papilloma virus gene, vector, strain and expression method |
EA201790365A1 (en) * | 2014-09-11 | 2017-07-31 | Кадила Хелзкэр Лимитед | HUMAN PAPILLOMA VIRUS ANTIGENES WITH GOOD IMMUNOLOGICAL PROPERTIES AND CONTAINING THEIR VACCINE |
RU2628693C1 (en) * | 2016-11-10 | 2017-08-21 | федеральное государственное бюджетное учреждение "Федеральный научно-исследовательский центр эпидемиологии и микробиологии имени почетного академика Н.Ф. Гамалеи" Министерства здравоохранения Российской Федерации (ФГБУ "ФНИЦЭМ им. Н.Ф. Гамалеи" Минздрава России) | Recombinant l1hpv16 gene, recombinant pqe-l1/16 plasmid, l1hpv16 protein and their application |
CN113528544B (en) * | 2021-06-02 | 2022-07-08 | 郑州大学 | Gene for coding soluble HPV23L1 protein and construction and application of recombinant plasmid thereof |
Family Cites Families (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB9621091D0 (en) * | 1996-10-09 | 1996-11-27 | Fondation Pour Le Perfectionem | Attenuated microorganisms strains and their uses |
RU2356943C2 (en) * | 2003-03-24 | 2009-05-27 | Мерк Энд Ко., Инк. | Nucleic acid molecule encoding hpv 31 l1, expression vector, host cell, virus-like particle and method of its obtainment, vaccine, pharmaceutical composition and methods involving them |
-
2005
- 2005-06-20 CN CN2005800278872A patent/CN101115766B/en not_active Expired - Fee Related
- 2005-06-20 JP JP2007516066A patent/JP4769247B2/en not_active Expired - Fee Related
- 2005-06-20 WO PCT/IB2005/001725 patent/WO2005123762A2/en active Search and Examination
Also Published As
Publication number | Publication date |
---|---|
WO2005123762A3 (en) | 2006-04-27 |
WO2005123762A2 (en) | 2005-12-29 |
JP4769247B2 (en) | 2011-09-07 |
CN101115766A (en) | 2008-01-30 |
JP2008504020A (en) | 2008-02-14 |
CN101115766B (en) | 2013-05-08 |
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