WO2005118062A3 - A system and method for managing detrimental cardiac remodeling - Google Patents

A system and method for managing detrimental cardiac remodeling Download PDF

Info

Publication number
WO2005118062A3
WO2005118062A3 PCT/US2005/019089 US2005019089W WO2005118062A3 WO 2005118062 A3 WO2005118062 A3 WO 2005118062A3 US 2005019089 W US2005019089 W US 2005019089W WO 2005118062 A3 WO2005118062 A3 WO 2005118062A3
Authority
WO
WIPO (PCT)
Prior art keywords
managing
cardiac remodeling
administered
cardiac
encourage
Prior art date
Application number
PCT/US2005/019089
Other languages
French (fr)
Other versions
WO2005118062A2 (en
Inventor
M Mower M D Morton
Original Assignee
M Mower M D Morton
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by M Mower M D Morton filed Critical M Mower M D Morton
Priority to AU2005250010A priority Critical patent/AU2005250010A1/en
Priority to MXPA06013845A priority patent/MXPA06013845A/en
Priority to CA002566578A priority patent/CA2566578A1/en
Priority to EP05756496A priority patent/EP1753501A4/en
Priority to JP2007515490A priority patent/JP2008500883A/en
Publication of WO2005118062A2 publication Critical patent/WO2005118062A2/en
Priority to IL179649A priority patent/IL179649A0/en
Publication of WO2005118062A3 publication Critical patent/WO2005118062A3/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/18—Applying electric currents by contact electrodes
    • A61N1/32—Applying electric currents by contact electrodes alternating or intermittent currents
    • A61N1/36—Applying electric currents by contact electrodes alternating or intermittent currents for stimulation
    • A61N1/362—Heart stimulators
    • A61N1/3627—Heart stimulators for treating a mechanical deficiency of the heart, e.g. congestive heart failure or cardiomyopathy
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/18—Applying electric currents by contact electrodes
    • A61N1/32—Applying electric currents by contact electrodes alternating or intermittent currents
    • A61N1/36—Applying electric currents by contact electrodes alternating or intermittent currents for stimulation
    • A61N1/362—Heart stimulators
    • A61N1/365—Heart stimulators controlled by a physiological parameter, e.g. heart potential
    • A61N1/36592—Heart stimulators controlled by a physiological parameter, e.g. heart potential controlled by the heart rate variability
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/18—Applying electric currents by contact electrodes
    • A61N1/32—Applying electric currents by contact electrodes alternating or intermittent currents
    • A61N1/36—Applying electric currents by contact electrodes alternating or intermittent currents for stimulation
    • A61N1/362—Heart stimulators
    • A61N1/365—Heart stimulators controlled by a physiological parameter, e.g. heart potential
    • A61N1/368—Heart stimulators controlled by a physiological parameter, e.g. heart potential comprising more than one electrode co-operating with different heart regions
    • A61N1/3684—Heart stimulators controlled by a physiological parameter, e.g. heart potential comprising more than one electrode co-operating with different heart regions for stimulating the heart at multiple sites of the ventricle or the atrium
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/18—Applying electric currents by contact electrodes
    • A61N1/32—Applying electric currents by contact electrodes alternating or intermittent currents
    • A61N1/36—Applying electric currents by contact electrodes alternating or intermittent currents for stimulation
    • A61N1/362—Heart stimulators
    • A61N1/365—Heart stimulators controlled by a physiological parameter, e.g. heart potential
    • A61N1/368—Heart stimulators controlled by a physiological parameter, e.g. heart potential comprising more than one electrode co-operating with different heart regions
    • A61N1/3684—Heart stimulators controlled by a physiological parameter, e.g. heart potential comprising more than one electrode co-operating with different heart regions for stimulating the heart at multiple sites of the ventricle or the atrium
    • A61N1/36842—Multi-site stimulation in the same chamber
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/18—Applying electric currents by contact electrodes
    • A61N1/32—Applying electric currents by contact electrodes alternating or intermittent currents
    • A61N1/36—Applying electric currents by contact electrodes alternating or intermittent currents for stimulation
    • A61N1/362—Heart stimulators
    • A61N1/365—Heart stimulators controlled by a physiological parameter, e.g. heart potential
    • A61N1/368—Heart stimulators controlled by a physiological parameter, e.g. heart potential comprising more than one electrode co-operating with different heart regions
    • A61N1/3684—Heart stimulators controlled by a physiological parameter, e.g. heart potential comprising more than one electrode co-operating with different heart regions for stimulating the heart at multiple sites of the ventricle or the atrium
    • A61N1/36843—Bi-ventricular stimulation

Landscapes

  • Health & Medical Sciences (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Radiology & Medical Imaging (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Physiology (AREA)
  • Biophysics (AREA)
  • Hospice & Palliative Care (AREA)
  • Electrotherapy Devices (AREA)

Abstract

A system and method for managing and inhibiting cardiac remodeling in MI patients. Bi-­ventricular stimulation is constantly provided with and without sensing to encourage normal pumping of the heart on a consistent basis. Pulses are administered using an anodal pulse followed by a cathodal pulse to stimulate cardiac muscle contraction. Stem cells are administered to MI areas to encourage regeneration of cardiac tissue in the damaged area. Stimulation may be provide to both healthy and compromised cardiac tissue.
PCT/US2005/019089 2004-05-28 2005-05-31 A system and method for managing detrimental cardiac remodeling WO2005118062A2 (en)

Priority Applications (6)

Application Number Priority Date Filing Date Title
AU2005250010A AU2005250010A1 (en) 2004-05-28 2005-05-31 A system and method for managing detrimental cardiac remodeling
MXPA06013845A MXPA06013845A (en) 2004-05-28 2005-05-31 A system and method for managing detrimental cardiac remodeling.
CA002566578A CA2566578A1 (en) 2004-05-28 2005-05-31 A system and method for managing detrimental cardiac remodeling
EP05756496A EP1753501A4 (en) 2004-05-28 2005-05-31 A system and method for managing detrimental cardiac remodeling
JP2007515490A JP2008500883A (en) 2004-05-28 2005-05-31 System and method for managing harmful cardiac remodeling
IL179649A IL179649A0 (en) 2004-05-28 2006-11-28 A system and method for managing detrimental cardiac remodeling

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US57512104P 2004-05-28 2004-05-28
US60/575,121 2004-05-28

Publications (2)

Publication Number Publication Date
WO2005118062A2 WO2005118062A2 (en) 2005-12-15
WO2005118062A3 true WO2005118062A3 (en) 2007-04-12

Family

ID=35463374

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2005/019089 WO2005118062A2 (en) 2004-05-28 2005-05-31 A system and method for managing detrimental cardiac remodeling

Country Status (9)

Country Link
EP (1) EP1753501A4 (en)
JP (1) JP2008500883A (en)
KR (1) KR20070062455A (en)
CN (1) CN101076369A (en)
AU (1) AU2005250010A1 (en)
CA (1) CA2566578A1 (en)
IL (1) IL179649A0 (en)
MX (1) MXPA06013845A (en)
WO (1) WO2005118062A2 (en)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7787950B1 (en) 2006-11-03 2010-08-31 Pacesetter, Inc. Techniques for delivery of stem cell and related therapies to treat cardiac conditions
CN102458570B (en) * 2009-05-14 2014-08-06 三森神经科学有限公司 Endovascular electrostimulation near a carotid bifurcation in treating cerebrovascular conditions
CN102824197B (en) * 2012-09-21 2017-11-17 复旦大学附属华山医院 A kind of stem cell transplantation screw electrode for left ventricle
WO2019241673A1 (en) * 2018-06-14 2019-12-19 Medtronic, Inc. Delivery of cardiac pacing therapy for cardiac remodeling
WO2019241658A2 (en) 2018-06-14 2019-12-19 Medtronic, Inc. Delivery of cardiac pacing therapy for cardiac remodeling

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5735879A (en) * 1993-08-06 1998-04-07 Heartstream, Inc. Electrotherapy method for external defibrillators

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6151525A (en) * 1997-11-07 2000-11-21 Medtronic, Inc. Method and system for myocardial identifier repair
US6067470A (en) * 1998-03-05 2000-05-23 Mower Family Chf Treatment Irrevocable Trust System and method for multiple site biphasic stimulation to revert ventricular arrhythmias
US6411845B1 (en) * 1999-03-04 2002-06-25 Mower Chf Treatment Irrevocable Trust System for multiple site biphasic stimulation to revert ventricular arrhythmias
US20020124855A1 (en) * 2001-03-12 2002-09-12 Chachques Juan C. Method of providing a dynamic cellular cardiac support
US6628988B2 (en) * 2001-04-27 2003-09-30 Cardiac Pacemakers, Inc. Apparatus and method for reversal of myocardial remodeling with electrical stimulation
US6965797B2 (en) * 2002-09-13 2005-11-15 Cardiac Pacemakers, Inc. Method and apparatus for assessing and treating myocardial wall stress

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5735879A (en) * 1993-08-06 1998-04-07 Heartstream, Inc. Electrotherapy method for external defibrillators

Also Published As

Publication number Publication date
CN101076369A (en) 2007-11-21
AU2005250010A1 (en) 2005-12-15
EP1753501A2 (en) 2007-02-21
KR20070062455A (en) 2007-06-15
MXPA06013845A (en) 2007-04-16
WO2005118062A2 (en) 2005-12-15
IL179649A0 (en) 2007-05-15
JP2008500883A (en) 2008-01-17
EP1753501A4 (en) 2008-01-23
CA2566578A1 (en) 2005-12-15

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