WO2005102273A3 - Pharmaceutical compositions of a biguanide and a sulfonylurea - Google Patents

Pharmaceutical compositions of a biguanide and a sulfonylurea Download PDF

Info

Publication number
WO2005102273A3
WO2005102273A3 PCT/IB2005/001084 IB2005001084W WO2005102273A3 WO 2005102273 A3 WO2005102273 A3 WO 2005102273A3 IB 2005001084 W IB2005001084 W IB 2005001084W WO 2005102273 A3 WO2005102273 A3 WO 2005102273A3
Authority
WO
WIPO (PCT)
Prior art keywords
biguanide
sulfonylurea
pharmaceutical compositions
inner core
tablet
Prior art date
Application number
PCT/IB2005/001084
Other languages
French (fr)
Other versions
WO2005102273A2 (en
Inventor
Amit Kumar Kesarwani
Manish Chawla
Rajeev Singh Raghuvanshi
Ashok Rampal
Original Assignee
Ranbaxy Lab Ltd
Amit Kumar Kesarwani
Manish Chawla
Rajeev Singh Raghuvanshi
Ashok Rampal
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ranbaxy Lab Ltd, Amit Kumar Kesarwani, Manish Chawla, Rajeev Singh Raghuvanshi, Ashok Rampal filed Critical Ranbaxy Lab Ltd
Publication of WO2005102273A2 publication Critical patent/WO2005102273A2/en
Publication of WO2005102273A3 publication Critical patent/WO2005102273A3/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
    • A61K9/2054—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2013—Organic compounds, e.g. phospholipids, fats
    • A61K9/2018—Sugars, or sugar alcohols, e.g. lactose, mannitol; Derivatives thereof, e.g. polysorbates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2072—Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
    • A61K9/2086—Layered tablets, e.g. bilayer tablets; Tablets of the type inert core-active coat
    • A61K9/209—Layered tablets, e.g. bilayer tablets; Tablets of the type inert core-active coat containing drug in at least two layers or in the core and in at least one outer layer
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2095—Tabletting processes; Dosage units made by direct compression of powders or specially processed granules, by eliminating solvents, by melt-extrusion, by injection molding, by 3D printing

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)

Abstract

The present invention relates to a multiple-compression tablet comprising an immediate release inner core containing a sulfonylurea and an extended release outer coat containing a biguanide, wherein one surface of the inner core is exposed. Also provided are processes for the preparation of the tablet.
PCT/IB2005/001084 2004-04-22 2005-04-21 Pharmaceutical compositions of a biguanide and a sulfonylurea WO2005102273A2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IN762/DEL/2004 2004-04-22
IN762DE2004 2004-04-22

Publications (2)

Publication Number Publication Date
WO2005102273A2 WO2005102273A2 (en) 2005-11-03
WO2005102273A3 true WO2005102273A3 (en) 2006-05-18

Family

ID=35197483

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/IB2005/001084 WO2005102273A2 (en) 2004-04-22 2005-04-21 Pharmaceutical compositions of a biguanide and a sulfonylurea

Country Status (1)

Country Link
WO (1) WO2005102273A2 (en)

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2000040233A1 (en) * 1998-12-30 2000-07-13 Hexal Ag Pharmaceutical composition containing metformin, acarbose or glimepiride and optionally poly-(dimethyl)-siloxane
US20030187074A1 (en) * 2002-03-04 2003-10-02 Javed Hussain Oral compositions for treatment of diabetes

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2000040233A1 (en) * 1998-12-30 2000-07-13 Hexal Ag Pharmaceutical composition containing metformin, acarbose or glimepiride and optionally poly-(dimethyl)-siloxane
US20030187074A1 (en) * 2002-03-04 2003-10-02 Javed Hussain Oral compositions for treatment of diabetes

Also Published As

Publication number Publication date
WO2005102273A2 (en) 2005-11-03

Similar Documents

Publication Publication Date Title
IL177283A (en) Pyrazolopyrimidine compounds, use thereof for the preparation of medicaments and pharmaceutical compositions comprising same
IL219380A (en) Compounds of 2-substituted sulfonamido phenyl-n-substituted aryl-propionamide, processes for their preparation, medicaments comprising them and uses thereof
WO2006024479A3 (en) Pharmaceutical multiparticulate compositions comprising mycophenolic acid or mycophenolate sodium and combination compositions with rapamycin
WO2007146248A3 (en) Stable laquinimod preparations
WO2009117130A3 (en) Extended release forumulation containing a wax
EP1850664B8 (en) Pesticidal capsule formulation
WO2006011159A3 (en) Stabilized pharmaceutical composition containing rabeprazole sodium with improved bioavailability
WO2007097770A8 (en) Metoprolol succinate e.r. tablets and methods for their preparation
WO2007090661A3 (en) Active substance combination comprising azolylcarbinol compounds
WO2008023277A3 (en) Compositions containing coenzyme q-10 and dihydrolipoic acid
WO2008154234A3 (en) Extended release formulation of nevirapine
WO2006060542A3 (en) Formulations of substituted benzoxazoles
WO2005082329A3 (en) Process for the preparation of solid dosage forms of valsartan and hydrochlorthiazide
EP1584335A3 (en) Active substance combination comprising a carbinol composition and an opioid
WO2005107717A3 (en) Oral dosage form for the extended release of biguanide and sulfonylurea
WO2007099555A3 (en) Pharmaceutical tablet compositions containing irbesartan
WO2007009989A3 (en) COMPOSITION CONTAINING A SIO2-NANOPARTICLE LIPOSOMAL DISPERSION AND AN ß-1,3-LINKED GLUCAN-ETHER DERIVATIVE
IL176870A0 (en) Solid forms of montelukast acid, pharmaceutical compositions containing the same and processes for the preparation thereof
WO2006055663A3 (en) The use of novel antibacterial compounds
WO2005102273A3 (en) Pharmaceutical compositions of a biguanide and a sulfonylurea
WO2007052164A3 (en) A pharmaceutical formulation containing olanzapine
WO2008059298A3 (en) Pharmaceutical composition containing clopidogrel hydrogenesulphate of polymorph 1 form
WO2005097192A3 (en) Active substance combination of a carbinol compound and an opioid
WO2006005017A3 (en) Oral composition comprising carbamylating agent
WO2005051346A3 (en) Compositions comprising organic compounds

Legal Events

Date Code Title Description
AK Designated states

Kind code of ref document: A2

Designated state(s): AE AG AL AM AT AU AZ BA BB BG BR BW BY BZ CA CH CN CO CR CU CZ DE DK DM DZ EC EE EG ES FI GB GD GE GH GM HR HU ID IL IN IS JP KE KG KM KP KR KZ LC LK LR LS LT LU LV MA MD MG MK MN MW MX MZ NA NI NO NZ OM PG PH PL PT RO RU SC SD SE SG SK SL SM SY TJ TM TN TR TT TZ UA UG US UZ VC VN YU ZA ZM ZW

AL Designated countries for regional patents

Kind code of ref document: A2

Designated state(s): BW GH GM KE LS MW MZ NA SD SL SZ TZ UG ZM ZW AM AZ BY KG KZ MD RU TJ TM AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IS IT LT LU MC NL PL PT RO SE SI SK TR BF BJ CF CG CI CM GA GN GQ GW ML MR NE SN TD TG

121 Ep: the epo has been informed by wipo that ep was designated in this application
NENP Non-entry into the national phase

Ref country code: DE

WWW Wipo information: withdrawn in national office

Ref document number: DE

WWE Wipo information: entry into national phase

Ref document number: 6385/DELNP/2006

Country of ref document: IN

122 Ep: pct application non-entry in european phase