WO2005097079A3 - Controlled release dosage for gaba receptor agonist - Google Patents
Controlled release dosage for gaba receptor agonist Download PDFInfo
- Publication number
- WO2005097079A3 WO2005097079A3 PCT/US2005/011032 US2005011032W WO2005097079A3 WO 2005097079 A3 WO2005097079 A3 WO 2005097079A3 US 2005011032 W US2005011032 W US 2005011032W WO 2005097079 A3 WO2005097079 A3 WO 2005097079A3
- Authority
- WO
- WIPO (PCT)
- Prior art keywords
- receptor agonist
- controlled release
- release dosage
- gaba receptor
- gabab
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
- A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2022—Organic macromolecular compounds
- A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
- A61K9/2054—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
- A61K9/5005—Wall or coating material
- A61K9/5021—Organic macromolecular compounds
- A61K9/5026—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
- A61K9/5005—Wall or coating material
- A61K9/5021—Organic macromolecular compounds
- A61K9/5036—Polysaccharides, e.g. gums, alginate; Cyclodextrin
- A61K9/5042—Cellulose; Cellulose derivatives, e.g. phthalate or acetate succinate esters of hydroxypropyl methylcellulose
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
- A61K9/5073—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals having two or more different coatings optionally including drug-containing subcoatings
- A61K9/5078—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals having two or more different coatings optionally including drug-containing subcoatings with drug-free core
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
- A61K9/5084—Mixtures of one or more drugs in different galenical forms, at least one of which being granules, microcapsules or (coated) microparticles according to A61K9/16 or A61K9/50, e.g. for obtaining a specific release pattern or for combining different drugs
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/06—Anti-spasmodics, e.g. drugs for colics, esophagic dyskinesia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/10—Laxatives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/12—Antidiarrhoeals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1605—Excipients; Inactive ingredients
- A61K9/1629—Organic macromolecular compounds
- A61K9/1652—Polysaccharides, e.g. alginate, cellulose derivatives; Cyclodextrin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/167—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction with an outer layer or coating comprising drug; with chemically bound drugs or non-active substances on their surface
- A61K9/1676—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction with an outer layer or coating comprising drug; with chemically bound drugs or non-active substances on their surface having a drug-free core with discrete complete coating layer containing drug
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2072—Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
- A61K9/2077—Tablets comprising drug-containing microparticles in a substantial amount of supporting matrix; Multiparticulate tablets
- A61K9/2081—Tablets comprising drug-containing microparticles in a substantial amount of supporting matrix; Multiparticulate tablets with microcapsules or coated microparticles according to A61K9/50
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
- A61K9/5073—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals having two or more different coatings optionally including drug-containing subcoatings
Abstract
Priority Applications (8)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
AU2005231433A AU2005231433A1 (en) | 2004-04-02 | 2005-04-01 | Controlled release dosage for GABA receptor agonist |
MXPA06011322A MXPA06011322A (en) | 2004-04-02 | 2005-04-01 | Pharmaceutical dosage forms having immediate release and/or controlled release properties that contain a gabab. |
BRPI0509399-6A BRPI0509399A (en) | 2004-04-02 | 2005-04-01 | pharmaceutical dosage form |
CA002560995A CA2560995A1 (en) | 2004-04-02 | 2005-04-01 | Controlled release dosage for gaba receptor agonist |
JP2007506301A JP2007531727A (en) | 2004-04-02 | 2005-04-01 | Pharmaceutical dosage form with immediate and / or controlled release properties containing a GABAB receptor agonist |
EP05733181A EP1729740A2 (en) | 2004-04-02 | 2005-04-01 | PHARMACEUTICAL DOSAGE FORMS HAVING IMMEDIATE RELEASE AND/OR CONTROLLED RELEASE PROPERTIES THAT CONTAIN A GABA<SB>B</SB> RECEPTOR AGONIST |
IL178296A IL178296A0 (en) | 2004-04-02 | 2006-09-26 | Pharmaceutical compositions containing a gaba?? receptor agonist |
NO20065013A NO20065013L (en) | 2004-04-02 | 2006-11-01 | Controlled release dosage for GABA receptor agonist |
Applications Claiming Priority (8)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US10/815,926 US20050220873A1 (en) | 2004-04-02 | 2004-04-02 | Pharmaceutical dosage forms having immediate and controlled release properties that contain a GABAB receptor agonist |
US10/815,930 US20050220874A1 (en) | 2004-04-02 | 2004-04-02 | Pharmaceutical dosage forms having immediate release and controlled release properties that contain a GABAB receptor agonist |
US10/815,930 | 2004-04-02 | ||
US10/815,926 | 2004-04-02 | ||
US10/815,924 | 2004-04-02 | ||
US10/815,924 US20050220863A1 (en) | 2004-04-02 | 2004-04-02 | Pharmaceutical dosage forms having controlled release properties that contain a GABAB receptor agonist |
US10/815,929 US20050220864A1 (en) | 2004-04-02 | 2004-04-02 | Pharmaceutical dosage forms having controlled release properties that contain a GABAB receptor agonist |
US10/815,929 | 2004-04-02 |
Publications (2)
Publication Number | Publication Date |
---|---|
WO2005097079A2 WO2005097079A2 (en) | 2005-10-20 |
WO2005097079A3 true WO2005097079A3 (en) | 2006-01-05 |
Family
ID=35060819
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PCT/US2005/011032 WO2005097079A2 (en) | 2004-04-02 | 2005-04-01 | Controlled release dosage for gaba receptor agonist |
Country Status (11)
Country | Link |
---|---|
EP (1) | EP1729740A2 (en) |
JP (1) | JP2007531727A (en) |
KR (1) | KR20070020022A (en) |
AU (1) | AU2005231433A1 (en) |
BR (1) | BRPI0509399A (en) |
CA (1) | CA2560995A1 (en) |
IL (1) | IL178296A0 (en) |
MX (1) | MXPA06011322A (en) |
NO (1) | NO20065013L (en) |
TW (1) | TW200536523A (en) |
WO (1) | WO2005097079A2 (en) |
Families Citing this family (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP2010515754A (en) * | 2007-01-11 | 2010-05-13 | ゼノポート,インコーポレイティド | Sustained release oral dosage form of prodrug of R-baclofen and method of treatment |
WO2009096985A1 (en) * | 2008-02-01 | 2009-08-06 | Xenoport, Inc. | Sustained release particulate oral dosage forms of (r)-baclofen prodrugs and methods of treatment |
EP2403486A1 (en) | 2009-03-03 | 2012-01-11 | XenoPort, Inc. | Sustained release oral dosage forms of an r-baclofen prodrug |
RU2672884C1 (en) * | 2017-11-07 | 2018-11-20 | Федеральное государственное бюджетное образовательное учреждение высшего образования "Российский государственный педагогический университет им. А.И. Герцена" (РГПУ им. А.И. Герцена) | Agent for preserving population of gaba-ergic neurons after acute perinatal hypoxia |
JP7138666B2 (en) * | 2018-01-24 | 2022-09-16 | 大原薬品工業株式会社 | METHOD FOR IMPROVING CHEMICAL STABILITY OF TABLETS CONTAINING γ-AMINOBUTYRIC ACID DERIVATIVES |
Citations (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5719185A (en) * | 1993-04-23 | 1998-02-17 | Glaxo Group Limited | Use for GABA agonists for treating emesis |
US6544998B2 (en) * | 2000-11-30 | 2003-04-08 | Pfizer Inc | Combination of gaba agonists and sorbitol dehydrogenase inhibitors |
-
2005
- 2005-04-01 AU AU2005231433A patent/AU2005231433A1/en not_active Abandoned
- 2005-04-01 BR BRPI0509399-6A patent/BRPI0509399A/en not_active IP Right Cessation
- 2005-04-01 WO PCT/US2005/011032 patent/WO2005097079A2/en active Application Filing
- 2005-04-01 KR KR1020067022957A patent/KR20070020022A/en not_active Application Discontinuation
- 2005-04-01 JP JP2007506301A patent/JP2007531727A/en not_active Withdrawn
- 2005-04-01 MX MXPA06011322A patent/MXPA06011322A/en unknown
- 2005-04-01 CA CA002560995A patent/CA2560995A1/en not_active Abandoned
- 2005-04-01 EP EP05733181A patent/EP1729740A2/en not_active Withdrawn
- 2005-04-04 TW TW094110754A patent/TW200536523A/en unknown
-
2006
- 2006-09-26 IL IL178296A patent/IL178296A0/en unknown
- 2006-11-01 NO NO20065013A patent/NO20065013L/en not_active Application Discontinuation
Patent Citations (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5719185A (en) * | 1993-04-23 | 1998-02-17 | Glaxo Group Limited | Use for GABA agonists for treating emesis |
US6544998B2 (en) * | 2000-11-30 | 2003-04-08 | Pfizer Inc | Combination of gaba agonists and sorbitol dehydrogenase inhibitors |
Also Published As
Publication number | Publication date |
---|---|
MXPA06011322A (en) | 2007-02-21 |
WO2005097079A2 (en) | 2005-10-20 |
KR20070020022A (en) | 2007-02-16 |
IL178296A0 (en) | 2007-02-11 |
NO20065013L (en) | 2007-01-02 |
BRPI0509399A (en) | 2007-09-18 |
TW200536523A (en) | 2005-11-16 |
EP1729740A2 (en) | 2006-12-13 |
JP2007531727A (en) | 2007-11-08 |
CA2560995A1 (en) | 2005-10-20 |
AU2005231433A1 (en) | 2005-10-20 |
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