WO2005092378A3 - Anti-vglut glutamate transporter antibodies for use in pain therapy - Google Patents

Anti-vglut glutamate transporter antibodies for use in pain therapy Download PDF

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Publication number
WO2005092378A3
WO2005092378A3 PCT/EP2005/002695 EP2005002695W WO2005092378A3 WO 2005092378 A3 WO2005092378 A3 WO 2005092378A3 EP 2005002695 W EP2005002695 W EP 2005002695W WO 2005092378 A3 WO2005092378 A3 WO 2005092378A3
Authority
WO
WIPO (PCT)
Prior art keywords
vglut
pain
glutamate transporter
pain therapy
transporter antibodies
Prior art date
Application number
PCT/EP2005/002695
Other languages
French (fr)
Other versions
WO2005092378A2 (en
Inventor
Heribert Bohlen
Silke Schwengberg
Andreas Ehlich
Original Assignee
Axiogenesis Ag
Heribert Bohlen
Silke Schwengberg
Andreas Ehlich
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Axiogenesis Ag, Heribert Bohlen, Silke Schwengberg, Andreas Ehlich filed Critical Axiogenesis Ag
Publication of WO2005092378A2 publication Critical patent/WO2005092378A2/en
Publication of WO2005092378A3 publication Critical patent/WO2005092378A3/en

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Immunology (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

Pharmaceutical compositions as well as methods of alleviating pain, such as central pain, pain arising from cancer and phantom limb pain, are provided comprising administration of an antibody or antigen binding fragment thereof that specifically binds a VGLUT glutamate transporter.
PCT/EP2005/002695 2004-03-12 2005-03-14 Anti-vglut glutamate transporter antibodies for use in pain therapy WO2005092378A2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP04005998.2 2004-03-12
EP04005998 2004-03-12

Publications (2)

Publication Number Publication Date
WO2005092378A2 WO2005092378A2 (en) 2005-10-06
WO2005092378A3 true WO2005092378A3 (en) 2006-04-20

Family

ID=35056777

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/EP2005/002695 WO2005092378A2 (en) 2004-03-12 2005-03-14 Anti-vglut glutamate transporter antibodies for use in pain therapy

Country Status (1)

Country Link
WO (1) WO2005092378A2 (en)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2338485A1 (en) * 2009-12-14 2011-06-29 Grünenthal GmbH Substituted 1,3-dioxoisoindolines as medicine

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20020098473A1 (en) * 2000-07-25 2002-07-25 Edwards Robert H. Novel glutamate transporters
CA2450472A1 (en) * 2001-06-13 2002-12-19 Gruenenthal Gmbh Screening method using bnpi and dnpi

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20020098473A1 (en) * 2000-07-25 2002-07-25 Edwards Robert H. Novel glutamate transporters
CA2450472A1 (en) * 2001-06-13 2002-12-19 Gruenenthal Gmbh Screening method using bnpi and dnpi

Also Published As

Publication number Publication date
WO2005092378A2 (en) 2005-10-06

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