WO2005082900A3 - Amidoxines d'oxazolidinone utilisees en tant qu'agents antibacteriens - Google Patents

Amidoxines d'oxazolidinone utilisees en tant qu'agents antibacteriens Download PDF

Info

Publication number
WO2005082900A3
WO2005082900A3 PCT/IB2005/000119 IB2005000119W WO2005082900A3 WO 2005082900 A3 WO2005082900 A3 WO 2005082900A3 IB 2005000119 W IB2005000119 W IB 2005000119W WO 2005082900 A3 WO2005082900 A3 WO 2005082900A3
Authority
WO
WIPO (PCT)
Prior art keywords
amidoximes
oxazolidinone
antibacterial agents
present
compounds
Prior art date
Application number
PCT/IB2005/000119
Other languages
English (en)
Other versions
WO2005082900A2 (fr
Inventor
Mikhail Fedorovich Gordeev
Vara Prasad Venkata Na Josyula
Gary Wayne Luehr
Rama Jain
Original Assignee
Pharmacia & Upjohn Co Llc
Mikhail Fedorovich Gordeev
Vara Prasad Venkata Na Josyula
Gary Wayne Luehr
Rama Jain
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pharmacia & Upjohn Co Llc, Mikhail Fedorovich Gordeev, Vara Prasad Venkata Na Josyula, Gary Wayne Luehr, Rama Jain filed Critical Pharmacia & Upjohn Co Llc
Publication of WO2005082900A2 publication Critical patent/WO2005082900A2/fr
Publication of WO2005082900A3 publication Critical patent/WO2005082900A3/fr

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D263/00—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings
    • C07D263/52—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings condensed with carbocyclic rings or ring systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

L'invention se rapporte à de nouvelles amidoximes d'oxazolidinone représentées par la formule (I) dans laquelle R2, Y1, Y2, Y3, X, W, et Z sont définis ci-après dans le descriptif. Les composés de l'invention possèdent une activité puissante contre les bactéries gram positifs.
PCT/IB2005/000119 2004-01-28 2005-01-17 Amidoxines d'oxazolidinone utilisees en tant qu'agents antibacteriens WO2005082900A2 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US54021704P 2004-01-28 2004-01-28
US60/540,217 2004-01-28

Publications (2)

Publication Number Publication Date
WO2005082900A2 WO2005082900A2 (fr) 2005-09-09
WO2005082900A3 true WO2005082900A3 (fr) 2006-02-16

Family

ID=34910689

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/IB2005/000119 WO2005082900A2 (fr) 2004-01-28 2005-01-17 Amidoxines d'oxazolidinone utilisees en tant qu'agents antibacteriens

Country Status (1)

Country Link
WO (1) WO2005082900A2 (fr)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2121202B1 (fr) * 2006-12-19 2017-03-22 Basf Se Utilisation d'esters d'acides de cyclohexane polycarboxyliques pour la fabrication de matériaux de revêtement pour le procédé de revêtement de bobines et de bobines revêtues
US8841306B2 (en) 2008-11-20 2014-09-23 Panacea Biotec Ltd. Antimicrobials
CN102803224A (zh) 2009-06-26 2012-11-28 万能药生物有限公司 新的氮杂双环己烷类化合物

Citations (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5164510A (en) * 1988-09-15 1992-11-17 The Upjohn Company 5'Indolinyl-5β-amidomethyloxazolidin-2-ones
EP0738726A1 (fr) * 1995-04-21 1996-10-23 Bayer Ag Hétérobenzocyclopentane oxazolidinones ayant une activité antibactérienne
EP0785201A1 (fr) * 1996-01-18 1997-07-23 Bayer Ag Oxazolidinones substituées avec cyclopantopyridyl contenant des hétéroatomes
EP0789025A1 (fr) * 1996-02-06 1997-08-13 Bayer Ag Oxazolidinones substituées et leur utilisation comme médicaments antibactériens
WO1998007708A1 (fr) * 1996-08-21 1998-02-26 Pharmacia & Upjohn Company Derives d'isoxazoline utiles comme agents antimicrobiens
WO1998054161A1 (fr) * 1997-05-30 1998-12-03 Pharmacia & Upjohn Company Agents antibacteriens oxazolidinone ayant une fonctionnalite thiocarbonyle
WO2000010566A1 (fr) * 1998-08-24 2000-03-02 Bristol-Myers Squibb Company Nouveaux agents antibacteriens a base d'isoxazolinone
WO2000029409A1 (fr) * 1998-11-17 2000-05-25 Bayer Aktiengesellschaft Nouveaux derives d'oxazolidone substitues par un heterocyclyle
WO2002059115A1 (fr) * 2000-11-17 2002-08-01 Pharmacia & Upjohn Company Oxazolidinones a cycle benzenique comportant un heterocycle a six ou sept elements accole, utilisees comme agents antibacteriens
WO2003072553A1 (fr) * 2002-02-25 2003-09-04 Pharmacia & Upjohn Company N-aryl-2-oxazolidinone-5-carboxamides et leurs derives et utilisation de ces composes comme antibacteriens

Patent Citations (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5164510A (en) * 1988-09-15 1992-11-17 The Upjohn Company 5'Indolinyl-5β-amidomethyloxazolidin-2-ones
EP0738726A1 (fr) * 1995-04-21 1996-10-23 Bayer Ag Hétérobenzocyclopentane oxazolidinones ayant une activité antibactérienne
EP0785201A1 (fr) * 1996-01-18 1997-07-23 Bayer Ag Oxazolidinones substituées avec cyclopantopyridyl contenant des hétéroatomes
EP0789025A1 (fr) * 1996-02-06 1997-08-13 Bayer Ag Oxazolidinones substituées et leur utilisation comme médicaments antibactériens
WO1998007708A1 (fr) * 1996-08-21 1998-02-26 Pharmacia & Upjohn Company Derives d'isoxazoline utiles comme agents antimicrobiens
WO1998054161A1 (fr) * 1997-05-30 1998-12-03 Pharmacia & Upjohn Company Agents antibacteriens oxazolidinone ayant une fonctionnalite thiocarbonyle
WO2000010566A1 (fr) * 1998-08-24 2000-03-02 Bristol-Myers Squibb Company Nouveaux agents antibacteriens a base d'isoxazolinone
WO2000029409A1 (fr) * 1998-11-17 2000-05-25 Bayer Aktiengesellschaft Nouveaux derives d'oxazolidone substitues par un heterocyclyle
WO2002059115A1 (fr) * 2000-11-17 2002-08-01 Pharmacia & Upjohn Company Oxazolidinones a cycle benzenique comportant un heterocycle a six ou sept elements accole, utilisees comme agents antibacteriens
WO2003072553A1 (fr) * 2002-02-25 2003-09-04 Pharmacia & Upjohn Company N-aryl-2-oxazolidinone-5-carboxamides et leurs derives et utilisation de ces composes comme antibacteriens

Also Published As

Publication number Publication date
WO2005082900A2 (fr) 2005-09-09

Similar Documents

Publication Publication Date Title
WO2007064954A3 (fr) Analogues d'aminoglycoside 4,5-substitués antibactériens comportant plusieurs substituants
WO2006120563A3 (fr) Agents antibacteriens
IL177962A0 (en) Compounds and methods for treating dyslipidemia
WO2006092213A8 (fr) Pyrazolylcarboxanilides
WO2007067559A3 (fr) Agents antibacteriens
WO2010003533A3 (fr) Composés anti-infectieux
WO2008126034A3 (fr) Antibiotiques à base d'oxazolidinone
WO2007001335A3 (fr) Derives de la ramoplanine presentant une activite antibacterienne
WO2006105888A3 (fr) Combinaisons d'agents actifs fongicides synergiques
WO2006069363A3 (fr) Formes cristallines d'hydrochlorure de (r)-8-chloro-1-methyl-2,3,4,5-tetrahydro-1h-3-benzazepine
TW200716519A (en) Benzoyl-substituted serineamides
WO2006055070A3 (fr) Nouveaux derives de lincomycine possedant une activite anti-microbienne
WO2007070613A3 (fr) Analogues de la rifamycine et leurs utilisations
WO2011073112A3 (fr) Dérivés de mannose utilisés en tant qu'antagonistes de l'adhésion bactérienne
WO2008091416A3 (fr) Agents antimicrobiens antibiotiques et leurs procédés d'utilisation
WO2006105889A3 (fr) Combinaisons d'agents actifs fongicides synergiques
MY153763A (en) Quinazolinedione derivatives, preparation thereof and therapeutic uses thereof
WO2012037508A3 (fr) Agents antibactériens : dérivés de myxopyronine de puissance élevée
WO2004019683A3 (fr) Compositions antimicrobiennes
WO2004099197A3 (fr) Oxyarenes substitues
NZ545472A (en) 7-(4-substituted-3-cyclopropylaminomethyl-1-pyrrolidinyl)quinolonecarboxylic acid derivative
WO2008071961A8 (fr) Dérivés de 2-quinolinone et de 2-quinoxalinone et leur utilisation en tant qu'agents antibactériens
CA2627497C (fr) Compose amide heterocyclique et utilisation de celui-ci
WO2008019030A8 (fr) Composés d'azole modifiés en tant qu'agents anti-infectieux
WO2005082900A3 (fr) Amidoxines d'oxazolidinone utilisees en tant qu'agents antibacteriens

Legal Events

Date Code Title Description
AK Designated states

Kind code of ref document: A2

Designated state(s): AE AG AL AM AT AU AZ BA BB BG BR BW BY BZ CA CH CN CO CR CU CZ DE DK DM DZ EC EE EG ES FI GB GD GE GH GM HR HU ID IL IN IS JP KE KG KP KR KZ LC LK LR LS LT LU LV MA MD MG MK MN MW MX MZ NA NI NO NZ OM PG PH PL PT RO RU SC SD SE SG SK SL SM SY TJ TM TN TR TT TZ UA UG US UZ VC VN YU ZA ZM ZW

AL Designated countries for regional patents

Kind code of ref document: A2

Designated state(s): BW GH GM KE LS MW MZ NA SD SL SZ TZ UG ZM ZW AM AZ BY KG KZ MD RU TJ TM AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IS IT LT LU MC NL PL PT RO SE SI SK TR BF BJ CF CG CI CM GA GN GQ GW ML MR NE SN TD TG

DPEN Request for preliminary examination filed prior to expiration of 19th month from priority date (pct application filed from 20040101)
121 Ep: the epo has been informed by wipo that ep was designated in this application
NENP Non-entry into the national phase

Ref country code: DE

WWW Wipo information: withdrawn in national office

Country of ref document: DE

122 Ep: pct application non-entry in european phase