WO2005080579A3 - Taxadiene biosynthesis - Google Patents
Taxadiene biosynthesis Download PDFInfo
- Publication number
- WO2005080579A3 WO2005080579A3 PCT/GB2005/000578 GB2005000578W WO2005080579A3 WO 2005080579 A3 WO2005080579 A3 WO 2005080579A3 GB 2005000578 W GB2005000578 W GB 2005000578W WO 2005080579 A3 WO2005080579 A3 WO 2005080579A3
- Authority
- WO
- WIPO (PCT)
- Prior art keywords
- taxadiene
- plants
- biosynthesis
- ggdp
- metabolism
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/82—Vectors or expression systems specially adapted for eukaryotic hosts for plant cells, e.g. plant artificial chromosomes (PACs)
- C12N15/8241—Phenotypically and genetically modified plants via recombinant DNA technology
- C12N15/8242—Phenotypically and genetically modified plants via recombinant DNA technology with non-agronomic quality (output) traits, e.g. for industrial processing; Value added, non-agronomic traits
- C12N15/8243—Phenotypically and genetically modified plants via recombinant DNA technology with non-agronomic quality (output) traits, e.g. for industrial processing; Value added, non-agronomic traits involving biosynthetic or metabolic pathways, i.e. metabolic engineering, e.g. nicotine, caffeine
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/93—Ligases (6)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P15/00—Preparation of compounds containing at least three condensed carbocyclic rings
Abstract
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB0403847.7 | 2004-02-20 | ||
GBGB0403847.7A GB0403847D0 (en) | 2004-02-20 | 2004-02-20 | Methods and means |
Publications (2)
Publication Number | Publication Date |
---|---|
WO2005080579A2 WO2005080579A2 (en) | 2005-09-01 |
WO2005080579A3 true WO2005080579A3 (en) | 2006-03-30 |
Family
ID=32040111
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PCT/GB2005/000578 WO2005080579A2 (en) | 2004-02-20 | 2005-02-18 | Taxadiene biosynthesis |
Country Status (2)
Country | Link |
---|---|
GB (1) | GB0403847D0 (en) |
WO (1) | WO2005080579A2 (en) |
Families Citing this family (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP5166250B2 (en) | 2005-05-25 | 2013-03-21 | エクスプレッション、パソロジー、インコーポレイテッド | Multiplex method using liquid tissue preparations to increase the coverage of proteome from histopathologically processed biological samples |
CN104140689B (en) * | 2014-07-14 | 2016-02-17 | 红豆集团无锡南国企业有限公司 | The method of natural pigment is extracted from Ramulus et folium taxi cuspidatae pharmacy residue |
CN104450312B (en) * | 2014-11-27 | 2018-02-06 | 南京信息职业技术学院 | A kind of ferment soap and preparation method thereof |
CN104450316A (en) * | 2014-12-10 | 2015-03-25 | 江西省喜果绿化有限公司 | Taxus chinensis soap for dry skin |
CN111748547B (en) * | 2020-07-07 | 2021-12-03 | 中国农业科学院深圳农业基因组研究所 | Taxadiene synthase TcTS2, coding nucleotide sequence and application thereof |
Citations (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO1997038571A1 (en) * | 1996-04-15 | 1997-10-23 | Washington State University Research Foundation | Compositions and methods for taxol biosynthesis |
-
2004
- 2004-02-20 GB GBGB0403847.7A patent/GB0403847D0/en not_active Ceased
-
2005
- 2005-02-18 WO PCT/GB2005/000578 patent/WO2005080579A2/en active Application Filing
Patent Citations (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO1997038571A1 (en) * | 1996-04-15 | 1997-10-23 | Washington State University Research Foundation | Compositions and methods for taxol biosynthesis |
Non-Patent Citations (4)
Title |
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BRAMLEY PETER, TEULIERES CHANTAL, BLAIN IAN, BIRD COLIN SCHUCH WOLFGANG: "Biochemical characterisation of transgenic tomato plants in which carotenoid synthesis has been inhibited through the expression of antisense RNA to pTOM5", THE PLANT JOURNAL, vol. 2, no. 3, 1992, pages 343 - 349, XP002362541 * |
HUANG Q ET AL: "Engineering Escherichia coli for the synthesis of taxadiene, a key intermediate in the biosynthesis of taxol.", BIOORGANIC & MEDICINAL CHEMISTRY. SEP 2001, vol. 9, no. 9, September 2001 (2001-09-01), pages 2237 - 2242, XP002362540, ISSN: 0968-0896 * |
WILDUNG M R ET AL: "CDNA CLONE FOR TAXADIENE SYNTHASE, THE DITERPENE CYCLASE THAT CATALYZES THE COMMITTED STEP OF TAXOL BIOSYNTHESIS", JOURNAL OF BIOLOGICAL CHEMISTRY, AMERICAN SOCIETY OF BIOLOCHEMICAL BIOLOGISTS, BIRMINGHAM,, US, vol. 271, no. 16, 19 April 1996 (1996-04-19), pages 9201 - 9204, XP000938117, ISSN: 0021-9258 * |
WILLIAMS DAVID C ET AL: "Heterologous expression and characterization of a "pseudomature" form of taxadiene synthase involved in paclitaxel (taxol) biosynthesis and evaluation of a potential intermediate and inhibitors of the multistep diterpene cyclization reaction", ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS, vol. 379, no. 1, 1 July 2000 (2000-07-01), pages 137 - 146, XP002362542, ISSN: 0003-9861 * |
Also Published As
Publication number | Publication date |
---|---|
WO2005080579A2 (en) | 2005-09-01 |
GB0403847D0 (en) | 2004-03-24 |
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