WO2005074699A3 - Method for the production of solid dispersions - Google Patents

Method for the production of solid dispersions Download PDF

Info

Publication number
WO2005074699A3
WO2005074699A3 PCT/AT2005/000039 AT2005000039W WO2005074699A3 WO 2005074699 A3 WO2005074699 A3 WO 2005074699A3 AT 2005000039 W AT2005000039 W AT 2005000039W WO 2005074699 A3 WO2005074699 A3 WO 2005074699A3
Authority
WO
WIPO (PCT)
Prior art keywords
sugar
production
solid dispersions
extruder
mixtures
Prior art date
Application number
PCT/AT2005/000039
Other languages
German (de)
French (fr)
Other versions
WO2005074699A2 (en
Inventor
Thomas Tritthart
Original Assignee
Thomas Tritthart
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Thomas Tritthart filed Critical Thomas Tritthart
Publication of WO2005074699A2 publication Critical patent/WO2005074699A2/en
Publication of WO2005074699A3 publication Critical patent/WO2005074699A3/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1682—Processes
    • A61K9/1694—Processes resulting in granules or microspheres of the matrix type containing more than 5% of excipient
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L27/00—Spices; Flavouring agents or condiments; Artificial sweetening agents; Table salts; Dietetic salt substitutes; Preparation or treatment thereof
    • A23L27/10—Natural spices, flavouring agents or condiments; Extracts thereof
    • A23L27/12—Natural spices, flavouring agents or condiments; Extracts thereof from fruit, e.g. essential oils
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L27/00—Spices; Flavouring agents or condiments; Artificial sweetening agents; Table salts; Dietetic salt substitutes; Preparation or treatment thereof
    • A23L27/70—Fixation, conservation, or encapsulation of flavouring agents
    • A23L27/72—Encapsulation
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
    • A23L33/15—Vitamins
    • A23L33/155—Vitamins A or D
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23P—SHAPING OR WORKING OF FOODSTUFFS, NOT FULLY COVERED BY A SINGLE OTHER SUBCLASS
    • A23P10/00—Shaping or working of foodstuffs characterised by the products
    • A23P10/30—Encapsulation of particles, e.g. foodstuff additives
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23P—SHAPING OR WORKING OF FOODSTUFFS, NOT FULLY COVERED BY A SINGLE OTHER SUBCLASS
    • A23P30/00—Shaping or working of foodstuffs characterised by the process or apparatus
    • A23P30/20—Extruding
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1617—Organic compounds, e.g. phospholipids, fats
    • A61K9/1623—Sugars or sugar alcohols, e.g. lactose; Derivatives thereof; Homeopathic globules
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
    • A23V2002/00—Food compositions, function of food ingredients or processes for food or foodstuffs

Landscapes

  • Engineering & Computer Science (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Food Science & Technology (AREA)
  • Polymers & Plastics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nutrition Science (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Mycology (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Manufacturing & Machinery (AREA)
  • Medicinal Preparation (AREA)
  • Colloid Chemistry (AREA)
  • Manufacturing Of Micro-Capsules (AREA)

Abstract

The invention relates to a method for encapsulating substances in a matrix containing sugar, sugar alcohols, sugar substitutes or the mixtures thereof by extrusion using an extruder having one or more temperature zones. Said method is characterized in that the matrix and the substances to be encapsulated are extruded at a temperature in which the sugar, the sugar alcohols, the sugar substitutes or the mixtures thereof come out of the extruder in a partly molten state.
PCT/AT2005/000039 2004-02-04 2005-02-04 Method for the production of solid dispersions WO2005074699A2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
ATA158/2004 2004-02-04
AT0015804A AT500101A1 (en) 2004-02-04 2004-02-04 encapsulation

Publications (2)

Publication Number Publication Date
WO2005074699A2 WO2005074699A2 (en) 2005-08-18
WO2005074699A3 true WO2005074699A3 (en) 2005-10-06

Family

ID=34831624

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/AT2005/000039 WO2005074699A2 (en) 2004-02-04 2005-02-04 Method for the production of solid dispersions

Country Status (2)

Country Link
AT (1) AT500101A1 (en)
WO (1) WO2005074699A2 (en)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1969953A1 (en) * 2007-03-13 2008-09-17 Friesland Brands B.V. Allergen-free, protein-free or at least dairy free powdered nutritional compositions and the use thereof in food products
FR3007290B1 (en) * 2013-06-25 2015-06-26 Expressions Aromatiques PROCESS FOR THE PRODUCTION OF PELLETS CONTAINING AN ACTIVE INGREDIENT, DWO AND LOAD IN OPTIMIZED ACTIVE PRINCIPLE
DE102014104676A1 (en) * 2014-04-02 2015-10-08 Heraeus Medical Gmbh Fosfomycin preparation, a process for preparing the preparation and a polymethyl methacrylate bone cement powder containing the preparation
CN114041519A (en) * 2021-11-25 2022-02-15 浙江华康药业股份有限公司 Method for preparing xylitol granules capable of being directly tabletted
CN114601142B (en) * 2022-03-31 2023-12-22 鲜之然(天津)生物技术有限公司 Preparation method and application of pig bone seasoning powder

Citations (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0435450A2 (en) * 1989-11-22 1991-07-03 SPI POLYOLS, Inc. Crystalline sugar alcohol containing uniformly dispersed particulate pharmaceutical compound
US5370881A (en) * 1987-04-20 1994-12-06 Fuisz Technologies Ltd. Water-soluble delivery systems for hydrophobic liquids
US5472733A (en) * 1994-11-14 1995-12-05 Warner-Lambert Company Dry extrusion cooking of sugar or sugarless products
US5679398A (en) * 1990-12-14 1997-10-21 Roquette Freres Partially melt co-crystallized xylitol/sorbitol and a process for obtaining the same
WO2000025606A1 (en) * 1998-11-04 2000-05-11 Firmenich Sa Solid delivery systems for aroma ingredients
EP1013176A1 (en) * 1998-12-22 2000-06-28 Gergely, Gerhard Sugar and/or sugar alcohol containing matrix material and method for preparing the same
WO2001080822A2 (en) * 2000-04-20 2001-11-01 Ethypharm Effervescent granules and methods for their preparation

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5178850A (en) * 1988-06-30 1993-01-12 Ici Americas Inc. Crystalline sugar alcohol containing uniformly dispersed liquid pharmaceutical compound

Patent Citations (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5370881A (en) * 1987-04-20 1994-12-06 Fuisz Technologies Ltd. Water-soluble delivery systems for hydrophobic liquids
EP0435450A2 (en) * 1989-11-22 1991-07-03 SPI POLYOLS, Inc. Crystalline sugar alcohol containing uniformly dispersed particulate pharmaceutical compound
US5679398A (en) * 1990-12-14 1997-10-21 Roquette Freres Partially melt co-crystallized xylitol/sorbitol and a process for obtaining the same
US5472733A (en) * 1994-11-14 1995-12-05 Warner-Lambert Company Dry extrusion cooking of sugar or sugarless products
WO2000025606A1 (en) * 1998-11-04 2000-05-11 Firmenich Sa Solid delivery systems for aroma ingredients
EP1013176A1 (en) * 1998-12-22 2000-06-28 Gergely, Gerhard Sugar and/or sugar alcohol containing matrix material and method for preparing the same
WO2001080822A2 (en) * 2000-04-20 2001-11-01 Ethypharm Effervescent granules and methods for their preparation

Also Published As

Publication number Publication date
AT500101A1 (en) 2005-10-15
WO2005074699A2 (en) 2005-08-18

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