WO2005068481A3 - Ferrocene derivatives - Google Patents
Ferrocene derivatives Download PDFInfo
- Publication number
- WO2005068481A3 WO2005068481A3 PCT/GB2005/000133 GB2005000133W WO2005068481A3 WO 2005068481 A3 WO2005068481 A3 WO 2005068481A3 GB 2005000133 W GB2005000133 W GB 2005000133W WO 2005068481 A3 WO2005068481 A3 WO 2005068481A3
- Authority
- WO
- WIPO (PCT)
- Prior art keywords
- aryl
- carbon
- alkaryl
- aralkyl
- heteroaryl
- Prior art date
Links
- KTWOOEGAPBSYNW-UHFFFAOYSA-N ferrocene Chemical class [Fe+2].C=1C=C[CH-]C=1.C=1C=C[CH-]C=1 KTWOOEGAPBSYNW-UHFFFAOYSA-N 0.000 title abstract 2
- XYFCBTPGUUZFHI-UHFFFAOYSA-N Phosphine Chemical compound P XYFCBTPGUUZFHI-UHFFFAOYSA-N 0.000 abstract 4
- 125000003118 aryl group Chemical group 0.000 abstract 4
- 125000003342 alkenyl group Chemical group 0.000 abstract 3
- 125000002877 alkyl aryl group Chemical group 0.000 abstract 3
- 125000002947 alkylene group Chemical group 0.000 abstract 3
- 125000003710 aryl alkyl group Chemical group 0.000 abstract 3
- 125000000753 cycloalkyl group Chemical group 0.000 abstract 3
- 125000001072 heteroaryl group Chemical group 0.000 abstract 3
- 125000000592 heterocycloalkyl group Chemical group 0.000 abstract 3
- 229910000073 phosphorus hydride Inorganic materials 0.000 abstract 2
- 125000000547 substituted alkyl group Chemical group 0.000 abstract 2
- 238000010485 C−C bond formation reaction Methods 0.000 abstract 1
- 125000000217 alkyl group Chemical group 0.000 abstract 1
- 150000001412 amines Chemical class 0.000 abstract 1
- 125000004432 carbon atom Chemical group C* 0.000 abstract 1
- CREMABGTGYGIQB-UHFFFAOYSA-N carbon carbon Chemical compound C.C CREMABGTGYGIQB-UHFFFAOYSA-N 0.000 abstract 1
- 239000011203 carbon fibre reinforced carbon Substances 0.000 abstract 1
- 238000010743 carbon-heteroatom bond forming reactions Methods 0.000 abstract 1
- 238000006555 catalytic reaction Methods 0.000 abstract 1
- 150000002148 esters Chemical class 0.000 abstract 1
- 229910052739 hydrogen Inorganic materials 0.000 abstract 1
- 239000001257 hydrogen Substances 0.000 abstract 1
- 125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 1
- 239000003446 ligand Substances 0.000 abstract 1
- 125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 abstract 1
- 125000001424 substituent group Chemical group 0.000 abstract 1
- 230000007704 transition Effects 0.000 abstract 1
- 229910052723 transition metal Inorganic materials 0.000 abstract 1
- 150000003624 transition metals Chemical class 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F17/00—Metallocenes
- C07F17/02—Metallocenes of metals of Groups 8, 9 or 10 of the Periodic Table
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
Abstract
The invention concerns a ferrocene derivative useful in the catalysis of carbon-carbon and/or carbonheteroatom bond forming reactions, the derivative having the Formula (I): or its enantiomer, wherein R1 has 3 or more contiguous carbon atoms and a branched chain structure providing bulk to the substituent and is selected from optionally substituted alkyl, alkenyl, aryl, cycloalkyl, alkaryl, aralkyl, heteroaryl and heterocycloalkyl groups, with the exception that R1 is not an arride, an amine, a phosphine or an ester;R2 and R3 are, independently, selected from optionally substítuted alkyl, alkenyl, aryl, cycloalkyl, alkaryl, aralkyl, heteroaryl and heterocycloalkyl groups, with the exception that R2 and R3 are not together C4-C8 alkylene, C4-C8 alkylene substituted by C1-C4 aryl or by phenyl, or annelated C4-C8 alkylene; and R4 is selected from hydrogen or from optionally substituted alkyl, alkenyl, aryl, cycloalkyl, alkaryl, aralkyl, heteroaryl and heterocycloalkyl groups, n is from 0 to 5, and each R4 may be the saure or different, with the exception that no R4 is a phosphine. The invention also provides a transition meta) complex comprising a transition metal coordinated with the ligand or Formula (I).
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB0400717A GB0400717D0 (en) | 2004-01-14 | 2004-01-14 | Ferrocene derivatives |
| GB0400717.5 | 2004-01-14 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| WO2005068481A2 WO2005068481A2 (en) | 2005-07-28 |
| WO2005068481A3 true WO2005068481A3 (en) | 2005-12-15 |
Family
ID=31726122
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PCT/GB2005/000133 WO2005068481A2 (en) | 2004-01-14 | 2005-01-14 | Ferrocene derivatives |
Country Status (2)
| Country | Link |
|---|---|
| GB (2) | GB0400717D0 (en) |
| WO (1) | WO2005068481A2 (en) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN107478700A (en) * | 2017-08-18 | 2017-12-15 | 中国医科大学 | For improving the electrochemical signals reinforcing agent and application method of nucleic acid detecting sensitivity |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP1894938A1 (en) * | 2006-08-31 | 2008-03-05 | Evonik Degussa GmbH | New cyclopentadienyl, indenyl or fluorenyl substituted phosphine compounds and their use in catalytic reactions |
| CN118373860A (en) * | 2024-06-25 | 2024-07-23 | 山东石油化工学院 | Bis (ferrocenyl) phosphine ion and preparation method and application thereof |
Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6133464A (en) * | 1996-10-07 | 2000-10-17 | Novartis Ag | Chiral ferrocenyls |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP3843470B2 (en) * | 1995-08-24 | 2006-11-08 | 日産化学工業株式会社 | Ferrocenyl diphenylphosphine derivative, hydrosilylation with the ligand metal complex |
| US6562989B2 (en) * | 2000-08-07 | 2003-05-13 | Yale University | Catalyst for aromatic C—O, C—N, and C—C bond formation |
-
2004
- 2004-01-14 GB GB0400717A patent/GB0400717D0/en not_active Ceased
-
2005
- 2005-01-14 GB GB0500699A patent/GB2410247A/en not_active Withdrawn
- 2005-01-14 WO PCT/GB2005/000133 patent/WO2005068481A2/en active Application Filing
Patent Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6133464A (en) * | 1996-10-07 | 2000-10-17 | Novartis Ag | Chiral ferrocenyls |
Non-Patent Citations (2)
| Title |
|---|
| NISHIBAYASHI Y ET AL: "NOVEL CHIRAL LIGANDS, DIFERROCENYL DICHALCOGENIDES AND THEIR DERIVATIVES, FOR RHODIUM- AND IRIDIUM-CATALYZED ASYMMETRIC HYDROSILYLATION", ORGANOMETALLICS, WASHINGTON, DC, US, vol. 15, 9 January 1996 (1996-01-09), pages 370 - 379, XP001146458, ISSN: 0276-7333 * |
| NISHIBAYASHI Y ET AL: "Synthesis and structure of novel chiral oxazolinylferrocenes and oxazolinylferrocenylphosphines, and their rhodium(I)-complexes", JOURNAL OF ORGANOMETALLIC CHEMISTRY, ELSEVIER-SEQUOIA S.A. LAUSANNE, CH, vol. 545-546, 30 October 1997 (1997-10-30), pages 381 - 398, XP004103354, ISSN: 0022-328X * |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN107478700A (en) * | 2017-08-18 | 2017-12-15 | 中国医科大学 | For improving the electrochemical signals reinforcing agent and application method of nucleic acid detecting sensitivity |
| CN107478700B (en) * | 2017-08-18 | 2019-08-09 | 中国医科大学 | For improving the electrochemical signals reinforcing agent and application method of nucleic acid detecting sensitivity |
Also Published As
| Publication number | Publication date |
|---|---|
| GB0500699D0 (en) | 2005-02-23 |
| WO2005068481A2 (en) | 2005-07-28 |
| GB2410247A (en) | 2005-07-27 |
| GB0400717D0 (en) | 2004-02-18 |
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