WO2005065655A3 - Procede de production de granules d'acide ceto-l-gulonique obtenus par pulverisation - Google Patents

Procede de production de granules d'acide ceto-l-gulonique obtenus par pulverisation Download PDF

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Publication number
WO2005065655A3
WO2005065655A3 PCT/EP2004/014824 EP2004014824W WO2005065655A3 WO 2005065655 A3 WO2005065655 A3 WO 2005065655A3 EP 2004014824 W EP2004014824 W EP 2004014824W WO 2005065655 A3 WO2005065655 A3 WO 2005065655A3
Authority
WO
WIPO (PCT)
Prior art keywords
gulonic acid
keto
acid spray
spray granules
drying installation
Prior art date
Application number
PCT/EP2004/014824
Other languages
German (de)
English (en)
Other versions
WO2005065655A2 (fr
Inventor
Martin Merger
Tillmann Faust
Robert Bayer
Original Assignee
Basf Ag
Martin Merger
Tillmann Faust
Robert Bayer
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Basf Ag, Martin Merger, Tillmann Faust, Robert Bayer filed Critical Basf Ag
Priority to EP04804409A priority Critical patent/EP1703897A2/fr
Publication of WO2005065655A2 publication Critical patent/WO2005065655A2/fr
Publication of WO2005065655A3 publication Critical patent/WO2005065655A3/fr

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/14Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1682Processes
    • A61K9/1688Processes resulting in pure drug agglomerate optionally containing up to 5% of excipient
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/185Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19Carboxylic acids, e.g. valproic acid
    • A61K31/191Carboxylic acids, e.g. valproic acid having two or more hydroxy groups, e.g. gluconic acid

Landscapes

  • Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

L'invention concerne un procédé de production de granulés d'acide céto-L-gulonique ayant une bonne faculté d'écoulement, ne formant pas de poussière, à partir d'acide céto-L-gluonique pur en fines particules. Selon ledit procédé, une solution d'acide céto-L-gulonique aqueuse ou contenant de l'eau est conduite à a) une installation de séchage par pulvérisation en lit fluidisé, b) une installation de séchage par pulvérisation à buse à un seul fluide ou c) une installation de séchage par pulvérisation à disque.
PCT/EP2004/014824 2004-01-05 2004-12-30 Procede de production de granules d'acide ceto-l-gulonique obtenus par pulverisation WO2005065655A2 (fr)

Priority Applications (1)

Application Number Priority Date Filing Date Title
EP04804409A EP1703897A2 (fr) 2004-01-05 2004-12-30 Procede de production de granules d'acide ceto-l-gulonique obtenus par pulverisation

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE200410001187 DE102004001187A1 (de) 2004-01-05 2004-01-05 Verfahren zur Herstellung von Keto-L-gulonsäuresprühgranulaten
DE102004001187.7 2004-01-05

Publications (2)

Publication Number Publication Date
WO2005065655A2 WO2005065655A2 (fr) 2005-07-21
WO2005065655A3 true WO2005065655A3 (fr) 2005-11-03

Family

ID=34716328

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/EP2004/014824 WO2005065655A2 (fr) 2004-01-05 2004-12-30 Procede de production de granules d'acide ceto-l-gulonique obtenus par pulverisation

Country Status (3)

Country Link
EP (1) EP1703897A2 (fr)
DE (1) DE102004001187A1 (fr)
WO (1) WO2005065655A2 (fr)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN107473959A (zh) * 2017-08-30 2017-12-15 沈阳农业大学 一种维生素c生产中的古龙酸减排提取法

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE102008045739B4 (de) 2008-09-04 2021-12-30 ABUS August Bremicker Söhne Kommanditgesellschaft Schließzylindersystem
CN103110105A (zh) * 2012-11-14 2013-05-22 江苏江山制药有限公司 食品添加剂无糖维生素c钠盐颗粒的生产方法
CN108774125A (zh) * 2018-05-28 2018-11-09 苏州澄江环境科技有限公司 一种从古龙酸母液中回收原料的工艺

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5268283A (en) * 1990-10-05 1993-12-07 Miles Inc. Method for the production of detergent builder formulations utilizing spray granulated citric acid and salts thereof
WO1997024454A1 (fr) * 1995-12-27 1997-07-10 Genencor International, Inc. Procede de preparation d'acide gluconique et acide gluconique ainsi produit
WO2001009074A1 (fr) * 1999-08-03 2001-02-08 Archer-Daniels-Midland Company Procede pour la recuperation d'acides organiques
US6187570B1 (en) * 1998-05-26 2001-02-13 The Electrosynthesis Company, Inc. Electrodialysis methods for purification and recovery of gluconic acid derivatives

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5268283A (en) * 1990-10-05 1993-12-07 Miles Inc. Method for the production of detergent builder formulations utilizing spray granulated citric acid and salts thereof
WO1997024454A1 (fr) * 1995-12-27 1997-07-10 Genencor International, Inc. Procede de preparation d'acide gluconique et acide gluconique ainsi produit
US6187570B1 (en) * 1998-05-26 2001-02-13 The Electrosynthesis Company, Inc. Electrodialysis methods for purification and recovery of gluconic acid derivatives
WO2001009074A1 (fr) * 1999-08-03 2001-02-08 Archer-Daniels-Midland Company Procede pour la recuperation d'acides organiques

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
AULTON M.E. (ED.): "Pharmaceutics: The science of dosage form design. 2nd edition", 2002, CHURCHILL LIVINGSTONE, LONDON, XP002342304 *
HERBENER R: "STAUBARME PULVER DURCH SPRUEHTROCKNEN - ERFAHRUNGEN MIT NEUEREN TECHNIKEN", CHEMIEINGENIEURTECHNIK, WILEY VCH., WEINHEIM, DE, vol. 59, no. 2, February 1987 (1987-02-01), pages 112 - 117, XP002026033, ISSN: 0009-286X *

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN107473959A (zh) * 2017-08-30 2017-12-15 沈阳农业大学 一种维生素c生产中的古龙酸减排提取法

Also Published As

Publication number Publication date
DE102004001187A1 (de) 2005-08-04
WO2005065655A2 (fr) 2005-07-21
EP1703897A2 (fr) 2006-09-27

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