WO2005051091A8 - Mimetic lipids and dietary supplements comprising the same - Google Patents

Mimetic lipids and dietary supplements comprising the same

Info

Publication number
WO2005051091A8
WO2005051091A8 PCT/IL2004/000959 IL2004000959W WO2005051091A8 WO 2005051091 A8 WO2005051091 A8 WO 2005051091A8 IL 2004000959 W IL2004000959 W IL 2004000959W WO 2005051091 A8 WO2005051091 A8 WO 2005051091A8
Authority
WO
WIPO (PCT)
Prior art keywords
essentially
naturally occurring
combination
mimetic
glycerophospholipids
Prior art date
Application number
PCT/IL2004/000959
Other languages
French (fr)
Other versions
WO2005051091A1 (en
Inventor
Avidor Shulman
Dror Gai Ben
Dori Pelled
Zohar Bar-On
Original Assignee
Enzymotec Ltd
Avidor Shulman
Dror Gai Ben
Dori Pelled
Zohar Bar-On
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Enzymotec Ltd, Avidor Shulman, Dror Gai Ben, Dori Pelled, Zohar Bar-On filed Critical Enzymotec Ltd
Publication of WO2005051091A1 publication Critical patent/WO2005051091A1/en
Publication of WO2005051091A8 publication Critical patent/WO2005051091A8/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23D—EDIBLE OILS OR FATS, e.g. MARGARINES, SHORTENINGS, COOKING OILS
    • A23D9/00—Other edible oils or fats, e.g. shortenings, cooking oils
    • A23D9/007—Other edible oils or fats, e.g. shortenings, cooking oils characterised by ingredients other than fatty acid triglycerides
    • A23D9/013—Other fatty acid esters, e.g. phosphatides
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23J—PROTEIN COMPOSITIONS FOR FOODSTUFFS; WORKING-UP PROTEINS FOR FOODSTUFFS; PHOSPHATIDE COMPOSITIONS FOR FOODSTUFFS
    • A23J7/00—Phosphatide compositions for foodstuffs, e.g. lecithin
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
    • A23L33/115—Fatty acids or derivatives thereof; Fats or oils
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/40—Complete food formulations for specific consumer groups or specific purposes, e.g. infant formula
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
    • A23V2002/00—Food compositions, function of food ingredients or processes for food or foodstuffs

Abstract

Disclosed is substantially homogenous lipid preparation comprising a combination of glycerophospholipids being phosphatidylcholine (PC), phosphatidylethanolamine (PE), phosphatidylserine (PS) and phosphatidylinositol (PI), wherein the quantitative ratio between said glycerophospholipids essentially mimics their corresponding ratio in naturally occurring human milk fat (HMF), optionally further comprising sphingomyelin (SM) and/or cholesterol, wherein the quantitative ratio between the glycerophospholipids in said combination and the sphingomyelin and/or cholesterol essentially mimics their corresponding ratio in said naturally occurring HMF. Further disclosed is the lipid combination which upon dispersion or emulsification in an essentially aqueous medium with other ingredients of infant formula, especially protein and fat under suitable conditions, forms a substantially homogenous dispersion or emulsion having a fat, globule-containing microstructure which is essentially mimetic of the corresponding globular microstructure of naturally occurring HMF, said globules having a membrane which is essentially mimetic of naturally occurring human milk fat globule membrane (HMFGM). Further disclosed are methods for preparing the lipid combination, and various uses thereof, particularly uses related to the preparation of infant formulas.
PCT/IL2004/000959 2003-10-22 2004-10-21 Mimetic lipids and dietary supplements comprising the same WO2005051091A1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IL158554 2003-10-22
IL15855403A IL158554A0 (en) 2003-10-22 2003-10-22 Mimetic lipids as dietary supplements

Publications (2)

Publication Number Publication Date
WO2005051091A1 WO2005051091A1 (en) 2005-06-09
WO2005051091A8 true WO2005051091A8 (en) 2005-08-04

Family

ID=34044224

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/IL2004/000959 WO2005051091A1 (en) 2003-10-22 2004-10-21 Mimetic lipids and dietary supplements comprising the same

Country Status (2)

Country Link
IL (1) IL158554A0 (en)
WO (1) WO2005051091A1 (en)

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102123614A (en) * 2008-06-16 2011-07-13 N.V.努特里奇亚 Composition with fat gradient
CN101909467B (en) * 2007-11-01 2013-04-24 恩兹默泰克有限公司 Lipid mixture for infant nutrition
CN110269103A (en) * 2019-07-19 2019-09-24 江南大学 A kind of butter oil ball and preparation method thereof

Families Citing this family (47)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
RU2480474C2 (en) 2005-04-28 2013-04-27 Энзимотек Лтд. Mixtures of polar lipids, production and use thereof
WO2008054192A1 (en) * 2006-11-02 2008-05-08 N.V. Nutricia Use of nutritional compositions for preventing disorders
DK1800675T3 (en) 2005-12-23 2011-09-05 Nutricia Nv Compositions comprising polyunsaturated fatty acids, proteins and manganese and / or molybdenum and nucleosides / nucleotides for the treatment of dementia
EP2305049A1 (en) * 2005-12-23 2011-04-06 N.V. Nutricia Infant nutritional compositions for preventing obesity
US20090117198A1 (en) 2006-05-31 2009-05-07 Hiroshi Kawakami Visceral fat accumulation inhibitor, and agent for promoting the increase in and/or inhibiting the decrease in blood adiponectin level
US20080003330A1 (en) * 2006-06-30 2008-01-03 Ricardo Rueda Infant formulas for early brain development
FR2908605A1 (en) * 2006-11-21 2008-05-23 Groupe Lactalis Use of an ingredient comprising concentrated milk fat globule membrane comprising polar lipids, total fatty substances, soluble proteins, to prepare food, drink or a food supplement for an indication involving intestinal wall
CN102894369B (en) 2007-10-19 2015-12-16 方塔拉合作集团有限公司 Keep or increase the method for growth or cognitive development
TWI366677B (en) 2007-12-28 2012-06-21 Ind Tech Res Inst Electrowetting display devices and fabrication methods thereof
EP3682874A1 (en) 2008-09-02 2020-07-22 N.V. Nutricia Nutritional compositions with coated lipid globules
WO2010068086A1 (en) * 2008-12-11 2010-06-17 N.V. Nutricia Nutritional compositions with large lipid globule size
WO2011108918A1 (en) * 2010-03-04 2011-09-09 N.V. Nutricia Modulation of post-prandial fat absorption
WO2011115476A1 (en) 2010-03-17 2011-09-22 N.V. Nutricia Infant nutrition for improving fatty acid composition of brain membranes later in life
RU2670880C9 (en) 2010-04-26 2018-12-11 Энзимотек Лтд. Source of plant-based fats
RU2012152320A (en) * 2010-05-06 2014-06-20 АЛЬФАКОР ФАРМА ЭлЭлСи DELIVERY OF CHOLESTEROL ETHERS TO STEROIDOGENIC TISSUES
EP2465359A1 (en) 2010-12-15 2012-06-20 Nestec S.A. Improved nutritional composition, especially for infants, with particular fat particles
WO2012173467A1 (en) 2011-06-16 2012-12-20 N.V. Nutricia Metabolic imprinting effects of specifically designed lipid component
EP2638811A1 (en) 2012-03-15 2013-09-18 N.V. Nutricia Process for preparing infant formula
EP2638810A1 (en) 2012-03-15 2013-09-18 N.V. Nutricia Process for preparing infant formula
WO2013191533A1 (en) 2012-06-18 2013-12-27 N.V. Nutricia Metabolic imprinting effects of nutrition with large lipid globules comprising milk fat and vegetable fat
US20140037813A1 (en) * 2012-08-02 2014-02-06 Mead Johnson Nutrition Company Nutritional creamer composition
WO2014058301A1 (en) * 2012-10-12 2014-04-17 N.V. Nutricia Infant nutrition with lipid globules to increase energy expenditure and metabolic flexibility later in life
US10455854B2 (en) 2013-03-11 2019-10-29 Mead Johnson Nutrition Company Nutritional compositions containing structured fat globules and uses thereof
US9661874B2 (en) * 2013-03-11 2017-05-30 Mead Johnson Nutrition Company Nutritional compositions containing structured fat globules and uses thereof
US20140255537A1 (en) * 2013-03-11 2014-09-11 Mead Johnson Nutrition Company Nutritional Compositions Containing an Enriched Lipid Fraction and Uses Thereof
US9980506B2 (en) 2013-03-11 2018-05-29 Mead Johnson Nutrition Co. Nutritional compositions containing structured fat globules and uses thereof
US10709770B2 (en) 2013-07-31 2020-07-14 Mead Johnson Nutrition Company Nutritional compositions containing a prebiotic and lactoferrin and uses thereof
US9609888B2 (en) 2013-07-31 2017-04-04 Mead Johnson Nutrition Company Nutritional compositions containing synergistic combination and uses thereof
EP3027063B1 (en) 2013-08-01 2018-11-21 Bunge Loders Croklaan B.V. Opo glyceride composition
WO2015036046A1 (en) * 2013-09-13 2015-03-19 N.V. Nutricia Improved process for preparing infant formula using a static mixer
WO2015036043A1 (en) 2013-09-13 2015-03-19 N.V. Nutricia Improved process for preparing infant formula using a rotary atomizer
WO2015065193A1 (en) 2013-11-01 2015-05-07 N.V. Nutricia Lipid composition for improving body composition during catch-up growth
WO2015086176A1 (en) 2013-12-12 2015-06-18 Nestec S.A. Synthetic milk compositions for infants less than three months old and for infants and children more than three months for ensuring optimal growth and preventing obesity
US20160015068A1 (en) * 2014-07-16 2016-01-21 Mead Johnson Nutrition Company Nutritional formulas containing oil blends and uses thereof
EP3087850A1 (en) 2015-03-16 2016-11-02 N.V. Nutricia Two-step emulsification process for preparing infant formula
WO2016163881A1 (en) * 2015-04-10 2016-10-13 N.V. Nutricia Nutrition with large lipid globules comprising vegetable fat coated with milk phospholipids for lipid digestion
US10582714B2 (en) 2015-07-10 2020-03-10 Mead Johnson Nutrition Company Nutritional compositions and methods for promoting cognitive development
EP3574771B1 (en) 2015-10-15 2022-11-16 N.V. Nutricia Infant formula with special lipid architecture for promoting healthy growth
BR122022002021B1 (en) * 2015-12-14 2023-03-14 Société des Produits Nestlé S.A. SYNTHETIC NUTRITIONAL COMPOSITION, ITS USE AND MINERAL
WO2018104512A1 (en) 2016-12-09 2018-06-14 N.V. Nutricia Nutritional composition for improving cell membranes
CN109418396A (en) * 2017-08-22 2019-03-05 中国农业大学 Artificial fat drips and its application
CN107549313B (en) * 2017-10-12 2020-09-22 中国农业科学院农产品加工研究所 Infant milk powder grease preparation method for simulating breast milk fat based on triglyceride analysis
EP3897209A1 (en) * 2018-12-20 2021-10-27 N.V. Nutricia Process for preparing an infant formula using freeze-drying
CN113115841A (en) * 2019-12-30 2021-07-16 丰益(上海)生物技术研发中心有限公司 Phospholipid-containing infant formula
CN111387339B (en) * 2020-02-20 2022-11-25 浙江工商大学 Large-size liposome with breast milk-simulated fat globule structure and preparation method thereof
AU2022365357A1 (en) * 2021-10-13 2024-03-28 Société des Produits Nestlé S.A. Nutritional composition for improving sleep
CN116106231B (en) * 2023-04-13 2023-07-07 北京三元食品股份有限公司 Method for evaluating similarity between sample and breast milk in multiple dimensions

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2033193B1 (en) * 1990-10-30 1994-01-16 Ganadera Union Ind Agro FAT MIXTURE FOR CHILD AND ADULT NUTRITION.
DE19845980A1 (en) * 1998-10-06 2000-04-13 Pierre Nicolas Foss Use of powdered human milk as a substitute for natural maternal milk
IL150240A (en) * 2002-06-16 2005-07-25 Lipogen Ltd Infant formula supplemented with phospholipids

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101909467B (en) * 2007-11-01 2013-04-24 恩兹默泰克有限公司 Lipid mixture for infant nutrition
CN102123614A (en) * 2008-06-16 2011-07-13 N.V.努特里奇亚 Composition with fat gradient
CN110269103A (en) * 2019-07-19 2019-09-24 江南大学 A kind of butter oil ball and preparation method thereof
CN110269103B (en) * 2019-07-19 2022-11-11 江南大学 Milk fat ball and preparation method thereof

Also Published As

Publication number Publication date
WO2005051091A1 (en) 2005-06-09
IL158554A0 (en) 2004-05-12

Similar Documents

Publication Publication Date Title
WO2005051091A8 (en) Mimetic lipids and dietary supplements comprising the same
Zarrabi et al. Nanoliposomes and tocosomes as multifunctional nanocarriers for the encapsulation of nutraceutical and dietary molecules
Acevedo-Fani et al. Biophysical insights into modulating lipid digestion in food emulsions
Lopez et al. Unraveling the complexity of milk fat globules to tailor bioinspired emulsions providing health benefits: The key role played by the biological membrane
Gallier et al. Surface characterization of bovine milk phospholipid monolayers by Langmuir isotherms and microscopic techniques
Deng Current progress in the utilization of soy-based emulsifiers in food applications—A Review
Singh et al. Structuring food emulsions in the gastrointestinal tract to modify lipid digestion
Liu et al. Emulsifying properties of acidic subunits of soy 11S globulin
Gallier et al. Using confocal laser scanning microscopy to probe the milk fat globule membrane and associated proteins
Comas et al. Creaming stability of oil in water (O/W) emulsions: Influence of pH on soybean protein–lecithin interaction
FI58715C (en) STEAM EMULSION FOR THE FRAME STATION EMULSION
RU2431414C2 (en) Food emulsion of oil and water
AU2015247529A1 (en) Plant based meat structured protein products
Waschatko et al. Soybean oleosomes behavior at the air–water interface
Ningtyas et al. Texture and lubrication properties of functional cream cheese: Effect of β‐glucan and phytosterol
Meynier et al. Molecular and structural organization of lipids in foods: their fate during digestion and impact in nutrition
Liu et al. Effect of particle size and interface composition on the lipid digestion of droplets covered with membrane phospholipids
Heo et al. Lecithin-based nano-emulsification improves the bioavailability of conjugated linoleic acid
Argov-Argaman et al. Lactosomes: structural and compositional classification of unique nanometer-sized protein lipid particles of human milk
Öztürk et al. Egg white powder‐stabilised multiple (water‐in‐olive oil‐in‐water) emulsions as beef fat replacers in model system meat emulsions
Ding et al. Preparation and pH stability of ferrous glycinate liposomes
Jacobsen et al. Partitioning of selected antioxidants in mayonnaise
Damodaran Straightforward process for removal of milk fat globule membranes and production of fat-free whey protein concentrate from cheese whey
Burling et al. Milk–A new source for bioactive phospholipids for use in food formulations
Thompson et al. Comparison of the structure and properties of liposomes prepared from milk fat globule membrane and soy phospholipids

Legal Events

Date Code Title Description
AK Designated states

Kind code of ref document: A1

Designated state(s): AE AG AL AM AT AU AZ BA BB BG BR BW BY BZ CA CH CN CO CR CU CZ DE DK DM DZ EC EE EG ES FI GB GD GE GH GM HR HU ID IL IN IS JP KE KG KP KR KZ LC LK LR LS LT LU LV MA MD MG MK MN MW MX MZ NA NI NO NZ OM PG PH PL PT RO RU SC SD SE SG SK SL SY TJ TM TN TR TT TZ UA UG US UZ VC VN YU ZA ZM ZW

AL Designated countries for regional patents

Kind code of ref document: A1

Designated state(s): BW GH GM KE LS MW MZ NA SD SL SZ TZ UG ZM ZW AM AZ BY KG KZ MD RU TJ TM AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IT LU MC NL PL PT RO SE SI SK TR BF BJ CF CG CI CM GA GN GQ GW ML MR NE SN TD TG

121 Ep: the epo has been informed by wipo that ep was designated in this application
WR Later publication of a revised version of an international search report
DPEN Request for preliminary examination filed prior to expiration of 19th month from priority date (pct application filed from 20040101)
122 Ep: pct application non-entry in european phase