WO2005041862A3 - Anticorps neutralisant l'hexosaminidase extracellulaire et utilises dans le traitement de l'arthrite - Google Patents

Anticorps neutralisant l'hexosaminidase extracellulaire et utilises dans le traitement de l'arthrite Download PDF

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Publication number
WO2005041862A3
WO2005041862A3 PCT/US2004/034318 US2004034318W WO2005041862A3 WO 2005041862 A3 WO2005041862 A3 WO 2005041862A3 US 2004034318 W US2004034318 W US 2004034318W WO 2005041862 A3 WO2005041862 A3 WO 2005041862A3
Authority
WO
WIPO (PCT)
Prior art keywords
hexosaminidase
arthritis
treatment
antibodies against
neutralizing antibodies
Prior art date
Application number
PCT/US2004/034318
Other languages
English (en)
Other versions
WO2005041862A2 (fr
Inventor
Brian M Clancy
Debra Denene Pittman
Original Assignee
Wyeth Corp
Brian M Clancy
Debra Denene Pittman
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Wyeth Corp, Brian M Clancy, Debra Denene Pittman filed Critical Wyeth Corp
Publication of WO2005041862A2 publication Critical patent/WO2005041862A2/fr
Publication of WO2005041862A3 publication Critical patent/WO2005041862A3/fr

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/40—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against enzymes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/76—Antagonist effect on antigen, e.g. neutralization or inhibition of binding

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Immunology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Enzymes And Modification Thereof (AREA)

Abstract

L'invention concerne des compositions et des procédés utilisés dans le traitement de l'arthrite comprenant des anticorps neutralisant une hexosaminidase extracellulaire.
PCT/US2004/034318 2003-10-23 2004-10-19 Anticorps neutralisant l'hexosaminidase extracellulaire et utilises dans le traitement de l'arthrite WO2005041862A2 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US51364103P 2003-10-23 2003-10-23
US60/513,641 2003-10-23

Publications (2)

Publication Number Publication Date
WO2005041862A2 WO2005041862A2 (fr) 2005-05-12
WO2005041862A3 true WO2005041862A3 (fr) 2006-08-03

Family

ID=34549294

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2004/034318 WO2005041862A2 (fr) 2003-10-23 2004-10-19 Anticorps neutralisant l'hexosaminidase extracellulaire et utilises dans le traitement de l'arthrite

Country Status (1)

Country Link
WO (1) WO2005041862A2 (fr)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN112999233B (zh) * 2019-12-19 2023-10-20 中国医学科学院药物研究所 一类来源于赤芍的单萜苷类化合物及其制法和应用

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2002048310A2 (fr) * 2000-12-15 2002-06-20 Genetics Institute, Llc Procedes et compositions permettant de diagnostiquer et de traiter la polyarthrite rhumatoide

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2002048310A2 (fr) * 2000-12-15 2002-06-20 Genetics Institute, Llc Procedes et compositions permettant de diagnostiquer et de traiter la polyarthrite rhumatoide
US20030154032A1 (en) * 2000-12-15 2003-08-14 Pittman Debra D. Methods and compositions for diagnosing and treating rheumatoid arthritis

Also Published As

Publication number Publication date
WO2005041862A2 (fr) 2005-05-12

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