WO2005040346A2 - Dispositif les techniques de sauvetage ou de restauration hematopoietique - Google Patents

Dispositif les techniques de sauvetage ou de restauration hematopoietique Download PDF

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Publication number
WO2005040346A2
WO2005040346A2 PCT/US2004/035133 US2004035133W WO2005040346A2 WO 2005040346 A2 WO2005040346 A2 WO 2005040346A2 US 2004035133 W US2004035133 W US 2004035133W WO 2005040346 A2 WO2005040346 A2 WO 2005040346A2
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WO
WIPO (PCT)
Prior art keywords
cells
bone marrow
hematopoietic
subject
biological composition
Prior art date
Application number
PCT/US2004/035133
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English (en)
Other versions
WO2005040346A3 (fr
Inventor
W. French Anderson
Yi Zhao
Original Assignee
University Of Southern California
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by University Of Southern California filed Critical University Of Southern California
Publication of WO2005040346A2 publication Critical patent/WO2005040346A2/fr
Publication of WO2005040346A3 publication Critical patent/WO2005040346A3/fr

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/28—Bone marrow; Haematopoietic stem cells; Mesenchymal stem cells of any origin, e.g. adipose-derived stem cells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L31/00—Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
    • A61L31/005—Ingredients of undetermined constitution or reaction products thereof

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Cell Biology (AREA)
  • Developmental Biology & Embryology (AREA)
  • Veterinary Medicine (AREA)
  • Immunology (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Hematology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Zoology (AREA)
  • Virology (AREA)
  • Biotechnology (AREA)
  • Biomedical Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Surgery (AREA)
  • Vascular Medicine (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

La présente invention concerne des techniques et des dispositifs permettant de sauver ou de restaurer la prolifération potentielle de cellules hématopoïétiques. Cette invention concerne en particulier des techniques et des dispositifs permettant de sauver et de restaurer le système hématopoïétique d'un sujet à la suite d'une thérapie par rayonnement et/ou d'une chimiothérapie sans qu'il soit nécessaire de transplanter de la moelle épinière. L'implantation de certaines compositions biologiques (tels que de la moelle épinière à faible densité ou que des cellules négatives par lignage) dans une poche ou un sac imperméable aux cellules, dans un animal dont la propres capacité hématopoïétique a été gravement compromise par un traitement de rayonnement et/ou par une chimiothérapie, par exemple, sauve ou restaure la capacité hématopoïétique de cet animal. Ce traitement peut remplacer ou augmenter les transplantations de moelle épinière, offrant de nombreux avantages dans le traitement des maladies hématopoïétiques, en particulier pour des maladies pour lesquelles on administre un traitement de rayonnement et/ou une chimiothérapie, telles que des cancers d'une manière générale et, plus particulièrement des troubles associés au sang tels que les leucémies et des lymphomes
PCT/US2004/035133 2003-10-24 2004-10-25 Dispositif les techniques de sauvetage ou de restauration hematopoietique WO2005040346A2 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US69257603A 2003-10-24 2003-10-24
US10/692,576 2003-10-24

Publications (2)

Publication Number Publication Date
WO2005040346A2 true WO2005040346A2 (fr) 2005-05-06
WO2005040346A3 WO2005040346A3 (fr) 2005-08-11

Family

ID=34522161

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2004/035133 WO2005040346A2 (fr) 2003-10-24 2004-10-25 Dispositif les techniques de sauvetage ou de restauration hematopoietique

Country Status (1)

Country Link
WO (1) WO2005040346A2 (fr)

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6464687B1 (en) * 1999-03-09 2002-10-15 Ball Semiconductor, Inc. Implantable drug delivery system

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6464687B1 (en) * 1999-03-09 2002-10-15 Ball Semiconductor, Inc. Implantable drug delivery system

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
HERODIN ET AL.: 'Short-term injection of antiapoptotic cytokine combination soon after lethal gamma irradiation promotes survival' BLOOD vol. 101, no. 7, April 2003, pages 2609 - 2616 *
TABBARA: 'Allogenic bone marrow transplantation' SOUTHERN MEDICAL JOURNAL vol. 89, no. 9, 1996, pages 857 - 868 *

Also Published As

Publication number Publication date
WO2005040346A3 (fr) 2005-08-11

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