WO2005034842A2 - Peptides utiles comme inhibiteurs de la fusion du vih - Google Patents

Peptides utiles comme inhibiteurs de la fusion du vih Download PDF

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Publication number
WO2005034842A2
WO2005034842A2 PCT/US2004/015841 US2004015841W WO2005034842A2 WO 2005034842 A2 WO2005034842 A2 WO 2005034842A2 US 2004015841 W US2004015841 W US 2004015841W WO 2005034842 A2 WO2005034842 A2 WO 2005034842A2
Authority
WO
WIPO (PCT)
Prior art keywords
segment
amino acid
residue
polypeptide
resides
Prior art date
Application number
PCT/US2004/015841
Other languages
English (en)
Inventor
William C. Olson
Norbert Schelke
Bryan O'hara
Original Assignee
Progenics Pharmaceuticals, Inc.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Progenics Pharmaceuticals, Inc. filed Critical Progenics Pharmaceuticals, Inc.
Publication of WO2005034842A2 publication Critical patent/WO2005034842A2/fr

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/005Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2740/00Reverse transcribing RNA viruses
    • C12N2740/00011Details
    • C12N2740/10011Retroviridae
    • C12N2740/16011Human Immunodeficiency Virus, HIV
    • C12N2740/16111Human Immunodeficiency Virus, HIV concerning HIV env
    • C12N2740/16122New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes

Abstract

L'invention concerne des polypeptides représentés par la formule α-β-η, ces polypeptides étant utiles pour inhiber la fusion entre le VIH-1 et les cellules CD4+. L'invention concerne également des compositions pharmaceutiques associées, des acides nucléiques, des systèmes hôte-vecteur, des articles de fabrication et des méthodes de production, de prévention et de traitement associées.
PCT/US2004/015841 2003-05-19 2004-05-19 Peptides utiles comme inhibiteurs de la fusion du vih WO2005034842A2 (fr)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US47208203P 2003-05-19 2003-05-19
US60/472,082 2003-05-19
US47333003P 2003-05-23 2003-05-23
US60/473,330 2003-05-23

Publications (1)

Publication Number Publication Date
WO2005034842A2 true WO2005034842A2 (fr) 2005-04-21

Family

ID=33479314

Family Applications (2)

Application Number Title Priority Date Filing Date
PCT/US2004/015825 WO2004103312A2 (fr) 2003-05-19 2004-05-19 Peptides utiles en tant qu'inhibiteurs de fusion du vih
PCT/US2004/015841 WO2005034842A2 (fr) 2003-05-19 2004-05-19 Peptides utiles comme inhibiteurs de la fusion du vih

Family Applications Before (1)

Application Number Title Priority Date Filing Date
PCT/US2004/015825 WO2004103312A2 (fr) 2003-05-19 2004-05-19 Peptides utiles en tant qu'inhibiteurs de fusion du vih

Country Status (1)

Country Link
WO (2) WO2004103312A2 (fr)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2022180007A1 (fr) * 2021-02-23 2022-09-01 Janssen Vaccines & Prevention B.V. Mutation de protéine d'enveloppe du vih stabilisant un trimère

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2006207181A1 (en) * 2005-01-24 2006-07-27 Yeda Research & Development Co. Ltd. HIV-1 gp41 fusion peptides for immunomodulation
CN100455594C (zh) * 2005-12-14 2009-01-28 中国人民解放军军事医学科学院生物工程研究所 抑制hiv病毒融合的多肽及其用途
BRPI0715794A2 (pt) * 2006-08-17 2013-07-23 Hoffmann La Roche conjugado de anticorpo contra ccr5 e peptÍdeo antifusogÊnico
TW200817438A (en) 2006-08-17 2008-04-16 Hoffmann La Roche A conjugate of an antibody against CCR5 and an antifusogenic peptide
AR067584A1 (es) 2007-07-20 2009-10-14 Hoffmann La Roche Un conjugado de un anticuerpo contra la cd4 y peptidos antifusogenicos
JP5788178B2 (ja) 2008-01-23 2015-09-30 ダナ ファーバー キャンサー インスティテュート インコーポレイテッド ウィルス感染症の治療のための組成物及び方法
WO2010148335A2 (fr) 2009-06-18 2010-12-23 Dana Farber Cancer Institute, Inc. Compositions de peptides viraux structurés et procédés d'utilisation

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5464933A (en) * 1993-06-07 1995-11-07 Duke University Synthetic peptide inhibitors of HIV transmission

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2022180007A1 (fr) * 2021-02-23 2022-09-01 Janssen Vaccines & Prevention B.V. Mutation de protéine d'enveloppe du vih stabilisant un trimère

Also Published As

Publication number Publication date
WO2004103312A2 (fr) 2004-12-02
WO2004103312A3 (fr) 2005-08-11

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