WO2005030137A3 - Improving biomechanical performance of irradiated biological material - Google Patents

Improving biomechanical performance of irradiated biological material Download PDF

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Publication number
WO2005030137A3
WO2005030137A3 PCT/US2004/031429 US2004031429W WO2005030137A3 WO 2005030137 A3 WO2005030137 A3 WO 2005030137A3 US 2004031429 W US2004031429 W US 2004031429W WO 2005030137 A3 WO2005030137 A3 WO 2005030137A3
Authority
WO
WIPO (PCT)
Prior art keywords
biological material
biomechanical performance
biological materials
irradiated biological
irradiated
Prior art date
Application number
PCT/US2004/031429
Other languages
French (fr)
Other versions
WO2005030137A2 (en
Inventor
Ozan Akkus
Original Assignee
Univ Toledo A University Instr
Ozan Akkus
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Toledo A University Instr, Ozan Akkus filed Critical Univ Toledo A University Instr
Publication of WO2005030137A2 publication Critical patent/WO2005030137A2/en
Publication of WO2005030137A3 publication Critical patent/WO2005030137A3/en

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/555—Heterocyclic compounds containing heavy metals, e.g. hemin, hematin, melarsoprol

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Addition Polymer Or Copolymer, Post-Treatments, Or Chemical Modifications (AREA)
  • Materials For Medical Uses (AREA)

Abstract

Compositions, and methods of making, at least one irradiated, sterilized and biomechanically strengthened biological material are described. The biological materials are treated with at least one substance that has a high affinity for free radicals. The biological materials have a molecular or supramolecular level of porosity which allows for the penetration of molecules of the high affinity free radical scavenging substance into the biological materials.
PCT/US2004/031429 2003-09-24 2004-09-24 Improving biomechanical performance of irradiated biological material WO2005030137A2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US50563503P 2003-09-24 2003-09-24
US60/505,635 2003-09-24

Publications (2)

Publication Number Publication Date
WO2005030137A2 WO2005030137A2 (en) 2005-04-07
WO2005030137A3 true WO2005030137A3 (en) 2005-09-01

Family

ID=34393045

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2004/031429 WO2005030137A2 (en) 2003-09-24 2004-09-24 Improving biomechanical performance of irradiated biological material

Country Status (1)

Country Link
WO (1) WO2005030137A2 (en)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20060074466A1 (en) * 2004-10-04 2006-04-06 Lostec, Inc. Compositions having improved osteogenesis and methods for making and using same
US8580192B2 (en) * 2006-10-31 2013-11-12 Ethicon, Inc. Sterilization of polymeric materials
CN110220932B (en) * 2019-06-11 2022-08-26 大连工业大学 Method for rapidly detecting quality change of myofibrillar protein containing brown algae polyphenol in UVA irradiation process

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5362442A (en) * 1993-07-22 1994-11-08 2920913 Canada Inc. Method for sterilizing products with gamma radiation
US5403834A (en) * 1992-12-07 1995-04-04 Eukarion, Inc. Synthetic catalytic free radical scavengers useful as antioxidants for prevention and therapy of disease
US5733868A (en) * 1996-04-16 1998-03-31 Depuy Orthopaedics, Inc. Poly(amino acid) adhesive tissue grafts

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5403834A (en) * 1992-12-07 1995-04-04 Eukarion, Inc. Synthetic catalytic free radical scavengers useful as antioxidants for prevention and therapy of disease
US5362442A (en) * 1993-07-22 1994-11-08 2920913 Canada Inc. Method for sterilizing products with gamma radiation
US5733868A (en) * 1996-04-16 1998-03-31 Depuy Orthopaedics, Inc. Poly(amino acid) adhesive tissue grafts

Also Published As

Publication number Publication date
WO2005030137A2 (en) 2005-04-07

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