WO2005026204A3 - Polypeptides antimicrobiens synthetiques - Google Patents

Polypeptides antimicrobiens synthetiques Download PDF

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Publication number
WO2005026204A3
WO2005026204A3 PCT/DK2004/000606 DK2004000606W WO2005026204A3 WO 2005026204 A3 WO2005026204 A3 WO 2005026204A3 DK 2004000606 W DK2004000606 W DK 2004000606W WO 2005026204 A3 WO2005026204 A3 WO 2005026204A3
Authority
WO
WIPO (PCT)
Prior art keywords
polypeptides
synthetic antimicrobial
antimicrobial polypeptides
nucleic acid
relates
Prior art date
Application number
PCT/DK2004/000606
Other languages
English (en)
Other versions
WO2005026204A2 (fr
Inventor
Hans-Henrik Kristen Hoegenhaug
Original Assignee
Novozymes As
Hans-Henrik Kristen Hoegenhaug
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Novozymes As, Hans-Henrik Kristen Hoegenhaug filed Critical Novozymes As
Priority to EP04762826A priority Critical patent/EP1664107A2/fr
Priority to NZ545815A priority patent/NZ545815A/en
Priority to CA2538085A priority patent/CA2538085C/fr
Priority to AU2004272170A priority patent/AU2004272170B2/en
Priority to JP2006525632A priority patent/JP2007527228A/ja
Priority to BRPI0414253-5A priority patent/BRPI0414253A/pt
Priority to US11/030,232 priority patent/US7250398B2/en
Publication of WO2005026204A2 publication Critical patent/WO2005026204A2/fr
Publication of WO2005026204A3 publication Critical patent/WO2005026204A3/fr
Priority to IL174092A priority patent/IL174092A/en
Priority to US11/766,178 priority patent/US7833967B2/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
    • C07K14/4723—Cationic antimicrobial peptides, e.g. defensins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/02—Local antiseptics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A61P31/06—Antibacterial agents for tuberculosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/10—Antimycotics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A61P33/02—Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A61P33/02—Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis
    • A61P33/06—Antimalarials
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biochemistry (AREA)
  • Pulmonology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Toxicology (AREA)
  • Zoology (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Breeding Of Plants And Reproduction By Means Of Culturing (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Cosmetics (AREA)
  • Detergent Compositions (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)

Abstract

L'invention concerne des polypeptides présentant une activité antimicrobienne et des polypeptides ayant une séquence nucléotide codant les polypeptides. L'invention concerne également des produits de synthèse d'acide nucléique, des vecteurs et des cellules hôtes comprenant lesdits produits de synthèse d'acide nucléique, ainsi que des procédés de production et d'utilisation des polypeptides.
PCT/DK2004/000606 2003-09-12 2004-09-13 Polypeptides antimicrobiens synthetiques WO2005026204A2 (fr)

Priority Applications (9)

Application Number Priority Date Filing Date Title
EP04762826A EP1664107A2 (fr) 2003-09-12 2004-09-13 Polypeptides antimicrobiens synthetiques
NZ545815A NZ545815A (en) 2003-09-12 2004-09-13 Synthetic antimicrobial polypeptides
CA2538085A CA2538085C (fr) 2003-09-12 2004-09-13 Polypeptides antimicrobiens synthetiques
AU2004272170A AU2004272170B2 (en) 2003-09-12 2004-09-13 Synthetic antimicrobial polypeptides
JP2006525632A JP2007527228A (ja) 2003-09-12 2004-09-13 合成抗微生物性ポリペプチド
BRPI0414253-5A BRPI0414253A (pt) 2003-09-12 2004-09-13 polipeptìdeo, polinucleotìdeo, construção de ácido nucléico, vetor de expressão recombinante, célula hospedeira recombinante, métodos para produzir um polipeptìdeo, e para matar ou inibir o crescimento de células microbianas, composição, uso de um polipeptìdeo, planta transgênica, parte de planta ou célula vegetal, e, aditivo de ração animal
US11/030,232 US7250398B2 (en) 2003-09-12 2005-01-06 Synthetic antimicrobial polypeptides
IL174092A IL174092A (en) 2003-09-12 2006-03-02 Synthetic antimicrobial polypeptides
US11/766,178 US7833967B2 (en) 2003-09-12 2007-06-21 Synthetic antimicrobial polypeptides

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DKPA200301324 2003-09-12
DKPA200301324 2003-09-12

Related Child Applications (1)

Application Number Title Priority Date Filing Date
US11/030,232 Continuation US7250398B2 (en) 2003-09-12 2005-01-06 Synthetic antimicrobial polypeptides

Publications (2)

Publication Number Publication Date
WO2005026204A2 WO2005026204A2 (fr) 2005-03-24
WO2005026204A3 true WO2005026204A3 (fr) 2005-04-28

Family

ID=34306686

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/DK2004/000606 WO2005026204A2 (fr) 2003-09-12 2004-09-13 Polypeptides antimicrobiens synthetiques

Country Status (10)

Country Link
EP (1) EP1664107A2 (fr)
JP (1) JP2007527228A (fr)
CN (2) CN1878791A (fr)
AU (1) AU2004272170B2 (fr)
BR (1) BRPI0414253A (fr)
CA (1) CA2538085C (fr)
IL (1) IL174092A (fr)
NZ (1) NZ545815A (fr)
WO (1) WO2005026204A2 (fr)
ZA (1) ZA200601999B (fr)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NO20041892D0 (no) * 2004-05-07 2004-05-07 Uni I Tromso Novel crustacean proline-rich peptides
EP2236608B1 (fr) 2005-10-04 2016-12-07 Soligenix, Inc. Nouvelles peptides pour traiter et prévenir les troubles de type immunitaire, y compris le traitement et la prévention des infections en modulant l'immunité innée
JP2012100639A (ja) * 2010-11-09 2012-05-31 Kai:Kk 酵素処理液を使用する洗浄、塗布および抗菌処理方法

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1992022578A1 (fr) * 1991-06-14 1992-12-23 Lee Jong Youn Nouveaux polypeptides et leur utilisation
EP0665239A1 (fr) * 1994-01-26 1995-08-02 Consiglio Nazionale Delle Ricerche Dérivés peptidiques du bactenecin contenant l'activité antibacterienne
US5830993A (en) * 1995-04-10 1998-11-03 Kansas State University Research Foundation Synthetic antimicrobial peptide

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1992022578A1 (fr) * 1991-06-14 1992-12-23 Lee Jong Youn Nouveaux polypeptides et leur utilisation
EP0665239A1 (fr) * 1994-01-26 1995-08-02 Consiglio Nazionale Delle Ricerche Dérivés peptidiques du bactenecin contenant l'activité antibacterienne
US5830993A (en) * 1995-04-10 1998-11-03 Kansas State University Research Foundation Synthetic antimicrobial peptide

Non-Patent Citations (6)

* Cited by examiner, † Cited by third party
Title
ANDERSON R C ET AL: "Isolation and characterisation of proline/arginine-rich cathelicidin peptides from ovine neutrophils", BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, ACADEMIC PRESS INC. ORLANDO, FL, US, vol. 312, no. 4, 26 December 2003 (2003-12-26), pages 1139 - 1146, XP004476395, ISSN: 0006-291X *
HUTTNER K M ET AL: "Localization and genomic organization of sheep antimicrobial peptide genes", GENE: AN INTERNATIONAL JOURNAL ON GENES AND GENOMES, ELSEVIER SCIENCE PUBLISHERS, BARKING, GB, vol. 206, no. 1, 5 January 1998 (1998-01-05), pages 85 - 91, XP004102876, ISSN: 0378-1119 *
NIIDOME E.A.: "Antibacterial activity of Arg/Pro rich bactenecin 5 model peptides and their interaction with phospholipid membranes", BULL.CHEM.SOC.JPN, vol. 73, 2000, pages 1397 - 1402, XP008028277 *
NIIDOME TAKURO ET AL: "Structure and property of model peptides of proline/arginine-rich region in bactenecin 5", JOURNAL OF PEPTIDE RESEARCH, vol. 51, no. 5, May 1998 (1998-05-01), pages 337 - 345, XP000739868, ISSN: 1397-002X *
RAJ P A ET AL: "Delineation of an active fragment and poly(L-proline) II conformation for candidacidal activity of bactenecin 5.", BIOCHEMISTRY. UNITED STATES 9 APR 1996, vol. 35, no. 14, 9 April 1996 (1996-04-09), pages 4314 - 4325, XP002272963, ISSN: 0006-2960 *
SHAMOVA O ET AL: "Purification and properties of proline-rich antimicrobial peptides from sheep and goat leukocytes.", INFECTION AND IMMUNITY. AUG 1999, vol. 67, no. 8, August 1999 (1999-08-01), pages 4106 - 4111, XP002318719, ISSN: 0019-9567 *

Also Published As

Publication number Publication date
BRPI0414253A (pt) 2006-11-21
IL174092A0 (en) 2006-08-01
IL174092A (en) 2010-11-30
CA2538085A1 (fr) 2005-03-24
JP2007527228A (ja) 2007-09-27
NZ545815A (en) 2009-11-27
CN101113173A (zh) 2008-01-30
EP1664107A2 (fr) 2006-06-07
CN1878791A (zh) 2006-12-13
CA2538085C (fr) 2011-03-15
WO2005026204A2 (fr) 2005-03-24
ZA200601999B (en) 2007-02-28
AU2004272170B2 (en) 2011-04-07
AU2004272170A1 (en) 2005-03-24

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