WO2005023850A3 - Method for producing inosine and 5'-inosinic acid by fermentation using bacterium belonging to the genus escherichia - Google Patents

Method for producing inosine and 5'-inosinic acid by fermentation using bacterium belonging to the genus escherichia Download PDF

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Publication number
WO2005023850A3
WO2005023850A3 PCT/JP2004/013191 JP2004013191W WO2005023850A3 WO 2005023850 A3 WO2005023850 A3 WO 2005023850A3 JP 2004013191 W JP2004013191 W JP 2004013191W WO 2005023850 A3 WO2005023850 A3 WO 2005023850A3
Authority
WO
WIPO (PCT)
Prior art keywords
fermentation
genus escherichia
inosinic acid
bacterium belonging
producing inosine
Prior art date
Application number
PCT/JP2004/013191
Other languages
French (fr)
Other versions
WO2005023850A2 (en
Inventor
Natalia Pavlovna Zakataeva
Sergey Viktorovich Gronsky
Maria Vyacheslavovn Vitushkina
Vitaly Arkadievich Livshits
Original Assignee
Ajinomoto Kk
Natalia Pavlovna Zakataeva
Sergey Viktorovich Gronsky
Maria Vyacheslavovn Vitushkina
Vitaly Arkadievich Livshits
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ajinomoto Kk, Natalia Pavlovna Zakataeva, Sergey Viktorovich Gronsky, Maria Vyacheslavovn Vitushkina, Vitaly Arkadievich Livshits filed Critical Ajinomoto Kk
Publication of WO2005023850A2 publication Critical patent/WO2005023850A2/en
Publication of WO2005023850A3 publication Critical patent/WO2005023850A3/en

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P19/00—Preparation of compounds containing saccharide radicals
    • C12P19/26—Preparation of nitrogen-containing carbohydrates
    • C12P19/28—N-glycosides
    • C12P19/30—Nucleotides
    • C12P19/32—Nucleotides having a condensed ring system containing a six-membered ring having two N-atoms in the same ring, e.g. purine nucleotides, nicotineamide-adenine dinucleotide
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C07K14/24—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Enterobacteriaceae (F), e.g. Citrobacter, Serratia, Proteus, Providencia, Morganella, Yersinia
    • C07K14/245—Escherichia (G)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P19/00—Preparation of compounds containing saccharide radicals
    • C12P19/26—Preparation of nitrogen-containing carbohydrates
    • C12P19/28—N-glycosides
    • C12P19/38—Nucleosides
    • C12P19/40—Nucleosides having a condensed ring system containing a six-membered ring having two nitrogen atoms in the same ring, e.g. purine nucleosides

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Microbiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biophysics (AREA)
  • Medicinal Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)

Abstract

A method is provided for producing inosine or 5’-inosinic acid using a bacterium belonging to the genus Escherichia wherein inosine productivity of said bacterium enhanced by enhancing an activity of a protein coded by yicM gene
PCT/JP2004/013191 2003-09-03 2004-09-03 Method for producing inosine and 5'-inosinic acid by fermentation using bacterium belonging to the genus escherichia WO2005023850A2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
RU2003126890 2003-09-03
RU2003126890/13A RU2271391C2 (en) 2003-09-03 2003-09-03 METHOD FOR PREPARING INOSINE AND 5'-INOSINIC ACID BY FERMENTATION METHOD BY USING MICROORGANISMS BELONGING TO GENUS Escherichia

Publications (2)

Publication Number Publication Date
WO2005023850A2 WO2005023850A2 (en) 2005-03-17
WO2005023850A3 true WO2005023850A3 (en) 2005-10-06

Family

ID=34271288

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/JP2004/013191 WO2005023850A2 (en) 2003-09-03 2004-09-03 Method for producing inosine and 5'-inosinic acid by fermentation using bacterium belonging to the genus escherichia

Country Status (2)

Country Link
RU (1) RU2271391C2 (en)
WO (1) WO2005023850A2 (en)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
RU2365622C2 (en) * 2006-12-22 2009-08-27 Закрытое акционерное общество "Научно-исследовательский институт Аджиномото-Генетика" (ЗАО АГРИ) METHOD OF PURINE NUCLEOZIDES AND NUCLEOTIDES PRODUCTION BY FERMENTATION WITH APPLICATION OF BACTERIA BELONGING TO GENUS Escherichia OR Bacillus
KR100882418B1 (en) 2007-01-15 2009-02-05 씨제이제일제당 (주) Inosine producing microorganism and a method of producing inosine using the same
KR101500846B1 (en) * 2013-07-23 2015-03-16 씨제이제일제당 (주) Method for preparing natural beef flavor
KR101500850B1 (en) * 2013-08-07 2015-03-18 씨제이제일제당 (주) Method for preparing IMP fermented liquor or glutamic acid fermented liquor for preparation of natural flavor
BR112016008830B1 (en) 2013-10-23 2023-02-23 Ajinomoto Co., Inc METHOD FOR PRODUCING A TARGET SUBSTANCE
EP3861109A1 (en) 2018-10-05 2021-08-11 Ajinomoto Co., Inc. Method for producing target substance by bacterial fermentation

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0857788A2 (en) * 1996-11-21 1998-08-12 Ajinomoto Co., Inc. Method for producing nucleoside-5'-phosphate ester
EP1004663A1 (en) * 1997-07-18 2000-05-31 Ajinomoto Co., Inc. Process for producing purine nucleosides via fermentation
EP1170370A2 (en) * 2000-07-05 2002-01-09 Ajinomoto Co., Inc. Method for producing nucleotide by fermentation

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0857788A2 (en) * 1996-11-21 1998-08-12 Ajinomoto Co., Inc. Method for producing nucleoside-5'-phosphate ester
EP1004663A1 (en) * 1997-07-18 2000-05-31 Ajinomoto Co., Inc. Process for producing purine nucleosides via fermentation
EP1170370A2 (en) * 2000-07-05 2002-01-09 Ajinomoto Co., Inc. Method for producing nucleotide by fermentation

Non-Patent Citations (7)

* Cited by examiner, † Cited by third party
Title
BURLAND V ET AL: "DNA sequence and analysis of 136 kilobases of the Escherichia coli genome: Organizational symmetry around the origin of replication", GENOMICS, vol. 16, 1993, pages 551 - 561, XP000615272, ISSN: 0888-7543 *
DATABASE EMBL [online] EBI; 13 December 2002 (2002-12-13), "Escherichia coli CFT073 section 15 of 18 of the complete genome.", XP002327821, retrieved from EBI accession no. EM_PRO:AE016769 Database accession no. AE016769 *
DATABASE EMBL [online] EBI; 19 May 1993 (1993-05-19), "E. coli; the region from 81.5 to 84.5 minutes.", XP002327820, retrieved from EBI accession no. EM_PRO:ECUW82 Database accession no. ECUW82 *
MATSUI H ET AL: "Investigation of various genotype characteristics for inosine accumulation in Escherichia coli W3110.", BIOSCIENCE, BIOTECHNOLOGY, AND BIOCHEMISTRY, vol. 65, no. 3, March 2001 (2001-03-01), pages 570 - 578, XP002327819, ISSN: 0916-8451 *
OGATA K: "The microbial production of nucleic acid-related compounds.", ADVANCES IN APPLIED MICROBIOLOGY. 1975, vol. 19, 1975, pages 209 - 247, XP008046823, ISSN: 0065-2164 *
RAVCHEEV D A ET AL: "Purine regulon of gamma-proteobacteria: A detailed description.", GENETIKA, vol. 38, no. 9, September 2002 (2002-09-01), pages 1203 - 1214, XP008046822, ISSN: 0016-6758 *
WELCH R A ET AL: "Extensive mosaic structure revealed by the complete genome sequence of uropathogenic Escherichia coli", PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF USA, vol. 99, no. 26, 24 December 2002 (2002-12-24), pages 17020 - 17024, XP002283177, ISSN: 0027-8424 *

Also Published As

Publication number Publication date
RU2271391C2 (en) 2006-03-10
WO2005023850A2 (en) 2005-03-17
RU2003126890A (en) 2005-03-10

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