WO2005021745A8 - 肝細胞癌に関連する遺伝子 - Google Patents

肝細胞癌に関連する遺伝子

Info

Publication number
WO2005021745A8
WO2005021745A8 PCT/JP2004/012425 JP2004012425W WO2005021745A8 WO 2005021745 A8 WO2005021745 A8 WO 2005021745A8 JP 2004012425 W JP2004012425 W JP 2004012425W WO 2005021745 A8 WO2005021745 A8 WO 2005021745A8
Authority
WO
WIPO (PCT)
Prior art keywords
associated gene
hepatocellular cancer
gene
evaluating cancer
cancer
Prior art date
Application number
PCT/JP2004/012425
Other languages
English (en)
French (fr)
Other versions
WO2005021745A1 (ja
Inventor
Mariko Esumi
Tadatoshi Takayama
Keiko Takagi
Original Assignee
Univ Nihon
Nippon Flour Mills
Mariko Esumi
Tadatoshi Takayama
Keiko Takagi
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Nihon, Nippon Flour Mills, Mariko Esumi, Tadatoshi Takayama, Keiko Takagi filed Critical Univ Nihon
Priority to EP04772381A priority Critical patent/EP1661991A4/en
Priority to US10/568,533 priority patent/US20110086342A1/en
Priority to JP2005513492A priority patent/JPWO2005021745A1/ja
Priority to CA002536324A priority patent/CA2536324A1/en
Publication of WO2005021745A1 publication Critical patent/WO2005021745A1/ja
Publication of WO2005021745A8 publication Critical patent/WO2005021745A8/ja

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/574—Immunoassay; Biospecific binding assay; Materials therefor for cancer
    • G01N33/57407—Specifically defined cancers
    • G01N33/57438—Specifically defined cancers of liver, pancreas or kidney
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
    • C12Q1/6886—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material for cancer
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/118—Prognosis of disease development
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/158—Expression markers

Abstract

本発明は、癌の評価方法であって、以下のステップ：　(a) 検体からtotal RNAを採取し、　(b) 表１～８に示される遺伝子の中の少なくとも１つ以上の遺伝子の発現量を測定し、(c) 前記測定結果を指標として癌を評価すること　を含む前記方法を提供する。
PCT/JP2004/012425 2003-08-22 2004-08-23 肝細胞癌に関連する遺伝子 WO2005021745A1 (ja)

Priority Applications (4)

Application Number Priority Date Filing Date Title
EP04772381A EP1661991A4 (en) 2003-08-24 2004-08-23 WITH HEPATOCELLULAR CARCINOMA ASSOCIATED GEN
US10/568,533 US20110086342A1 (en) 2003-08-22 2004-08-23 Hepatocellular Carcinoma-Associated Gene
JP2005513492A JPWO2005021745A1 (ja) 2003-08-22 2004-08-23 肝細胞癌に関連する遺伝子
CA002536324A CA2536324A1 (en) 2003-08-22 2004-08-23 Hepatocellular cancer-associated gene

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
JP2003-299363 2003-08-22
JP2003299363 2003-08-24
JP2003334444 2003-09-25
JP2003-334444 2003-09-25

Publications (2)

Publication Number Publication Date
WO2005021745A1 WO2005021745A1 (ja) 2005-03-10
WO2005021745A8 true WO2005021745A8 (ja) 2006-04-06

Family

ID=34277618

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/JP2004/012425 WO2005021745A1 (ja) 2003-08-22 2004-08-23 肝細胞癌に関連する遺伝子

Country Status (4)

Country Link
US (1) US20110086342A1 (ja)
JP (1) JPWO2005021745A1 (ja)
CA (1) CA2536324A1 (ja)
WO (1) WO2005021745A1 (ja)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2007020990A1 (ja) * 2005-08-12 2007-02-22 Nihon University Hcv陽性肝細胞癌の発癌・再発に関連する遺伝子
US20070117100A1 (en) * 2005-11-18 2007-05-24 Sun-Lung Tsai Biomarker for determining predisposition and/or prognosis of hepatocellular carcinoma
WO2007058623A1 (en) * 2005-11-21 2007-05-24 Singapore Health Services Pte Ltd Methods of predicting hepatocellular carcinoma recurrence by the determination of hepatocellular carcinoma recurrence-associated molecular biomarkers
JP5028615B2 (ja) * 2006-05-24 2012-09-19 国立大学法人金沢大学 遺伝子発現プロファイルによるｃ型肝硬変及び肝癌の検出
FR2910147B1 (fr) * 2006-12-19 2009-02-06 Galderma Res & Dev S N C Snc Methode correctrice de traitement de resultats d'experiences transcriptomiques obtenus par analyse differentielle
US20080274908A1 (en) * 2007-05-04 2008-11-06 Dermtech International Diagnosis of melanoma by nucleic acid analysis
JP4858344B2 (ja) * 2007-07-25 2012-01-18 ソニー株式会社 毛を用いた生体リズム情報取得方法
US8653047B2 (en) 2010-01-08 2014-02-18 Isis Pharmaceuticals, Inc. Modulation of angiopoietin-like 3 expression
KR20120022504A (ko) * 2010-07-30 2012-03-12 서울대학교산학협력단 간 질환의 진단, 치료 및 예방용 조성물
JP2015008686A (ja) * 2013-06-28 2015-01-19 三菱レイヨン株式会社 肝臓細胞又はその前駆細胞に由来する細胞の状態を評価する方法、並びに、その方法に用いるプローブ又はプローブセット及びマイクロアレイ
KR102198082B1 (ko) 2013-12-24 2021-01-05 아이오니스 파마수티컬즈, 인코포레이티드 안지오포이에틴-유사 3 발현의 조절
NO344051B1 (en) * 2017-05-04 2019-08-26 Patogen As Novel virus in Fish and Method for detection

Also Published As

Publication number Publication date
JPWO2005021745A1 (ja) 2006-10-26
US20110086342A1 (en) 2011-04-14
CA2536324A1 (en) 2005-03-10
WO2005021745A1 (ja) 2005-03-10

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