WO2005009362A3 - Muscarinic acetylcholine receptor antagonists - Google Patents

Muscarinic acetylcholine receptor antagonists Download PDF

Info

Publication number
WO2005009362A3
WO2005009362A3 PCT/US2004/023041 US2004023041W WO2005009362A3 WO 2005009362 A3 WO2005009362 A3 WO 2005009362A3 US 2004023041 W US2004023041 W US 2004023041W WO 2005009362 A3 WO2005009362 A3 WO 2005009362A3
Authority
WO
Grant status
Application
Patent type
Prior art keywords
receptor antagonists
acetylcholine receptor
muscarinic acetylcholine
muscarinic
methods
Prior art date
Application number
PCT/US2004/023041
Other languages
French (fr)
Other versions
WO2005009362A2 (en )
Inventor
Kristen E Belmonte
Jakob Busch-Petersen
Dramane Laine
Michael R Palovich
Original Assignee
Kristen E Belmonte
Jakob Busch-Petersen
Glaxo Group Ltd
Dramane Laine
Michael R Palovich
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D451/00Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof
    • C07D451/02Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof containing not further condensed 8-azabicyclo [3.2.1] octane or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane; Cyclic acetals thereof

Abstract

Muscarinic Acetylcholine Receptor Antagonists and methods of using them are provided.
PCT/US2004/023041 2003-07-17 2004-07-16 Muscarinic acetylcholine receptor antagonists WO2005009362A3 (en)

Priority Applications (2)

Application Number Priority Date Filing Date Title
US48798203 true 2003-07-17 2003-07-17
US60/487,982 2003-07-17

Applications Claiming Priority (10)

Application Number Priority Date Filing Date Title
JP2006520387A JP2007525478A (en) 2003-07-17 2004-07-16 Muscarinic acetylcholine receptor antagonist
US10565048 US7495010B2 (en) 2003-07-17 2004-07-16 Muscarinic acetylcholine receptor antagonists
AU2004259238A AU2004259238A1 (en) 2003-07-17 2004-07-16 Muscarinic acetylcholine receptor antagonists
EP20040778509 EP1648461A4 (en) 2003-07-17 2004-07-16 Muscarinic acetylcholine receptor antagonists
BRPI0412537A BRPI0412537A (en) 2003-07-17 2004-07-16 antagonist of muscarinic acetylcholine receptor
CA 2532433 CA2532433A1 (en) 2003-07-17 2004-07-16 Muscarinic acetylcholine receptor antagonists
MXPA06000663A MXPA06000663A (en) 2003-07-17 2004-07-16 Muscarinic acetylcholine receptor antagonists.
IL17291205A IL172912D0 (en) 2003-07-17 2005-12-29 Muscarinic acetylcholine receptor antagonists
IS8296A IS8296A (en) 2003-07-17 2006-02-13 Múskarínasetýlkólínviðtakamótlyf
NO20060777A NO20060777A (en) 2003-07-17 2006-02-17 muscarinic Acetylcholine

Publications (2)

Publication Number Publication Date
WO2005009362A2 true WO2005009362A2 (en) 2005-02-03
WO2005009362A3 true true WO2005009362A3 (en) 2005-04-07

Family

ID=34102736

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2004/023041 WO2005009362A3 (en) 2003-07-17 2004-07-16 Muscarinic acetylcholine receptor antagonists

Country Status (8)

Country Link
US (1) US7495010B2 (en)
EP (1) EP1648461A4 (en)
JP (1) JP2007525478A (en)
KR (1) KR20060054316A (en)
CN (1) CN1822839A (en)
CA (1) CA2532433A1 (en)
RU (1) RU2006104851A (en)
WO (1) WO2005009362A3 (en)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1897947A (en) * 2003-10-17 2007-01-17 葛兰素集团有限公司 Muscarinic acetylcholine receptor antagonists field of the invention
EP1725236A4 (en) * 2004-03-11 2009-05-13 Glaxo Group Ltd Novel m3 muscarinic acetylcholine receptor antagonists
US7384946B2 (en) * 2004-03-17 2008-06-10 Glaxo Group Limited M3 muscarinic acetylcholine receptor antagonists
JP2007529511A (en) * 2004-03-17 2007-10-25 グラクソ グループ リミテッドGlaxo Group Limited M3 muscarinic acetylcholine receptor antagonist
WO2005112644A3 (en) * 2004-05-13 2006-03-30 Glaxo Group Ltd Muscarinic acetylcholine receptor antagonists
EP1957075A4 (en) * 2004-11-15 2009-11-18 Glaxo Group Ltd Novel m3 muscarinic acetylcholine receptor antagonists
JP2009503099A (en) * 2005-08-02 2009-01-29 グラクソ グループ リミテッドGlaxo Group Limited M3 muscarinic acetylcholine receptor antagonist
US7767691B2 (en) * 2005-08-18 2010-08-03 Glaxo Group Limited Muscarinic acetylcholine receptor antagonists containing an azoniabiocyclo[2.2.1] heptane ring system
WO2010094643A1 (en) 2009-02-17 2010-08-26 Glaxo Group Limited Quinoline derivatives and their uses for rhinitis and urticaria
EP3248970A1 (en) 2016-05-27 2017-11-29 Zentiva K.S. Forms of umeclidinium bromide

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2800478A (en) * 1955-07-01 1957-07-23 Smith Kline French Lab 3-substituted-8-alkylnortropanes and the acid and quaternary ammonium salts thereof

Family Cites Families (31)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2800482A (en) * 1955-07-01 1957-07-23 Smith Kline French Lab Olefinic derivatives of 8-alkylnortropanes and the acid and quaternary ammonium salts thereof
US2800481A (en) * 1955-07-01 1957-07-23 Smith Kline French Lab Tertiary alcohol derivatives of 8-alkylnortropanes and the acid and quaternary ammonium salts thereof
GB2064336B (en) 1979-12-06 1984-03-14 Glaxo Group Ltd Device for dispensing medicaments
EP0069715B1 (en) 1981-07-08 1986-11-05 Aktiebolaget Draco Powder inhalator
GB2169265B (en) 1982-10-08 1987-08-12 Glaxo Group Ltd Pack for medicament
NL8601949A (en) 1985-07-30 1987-02-16 Glaxo Group Ltd Devices for administering medicaments to patients.
GB9004781D0 (en) 1990-03-02 1990-04-25 Glaxo Group Ltd Device
US5780466A (en) 1995-01-30 1998-07-14 Sanofi Substituted heterocyclic compounds method of preparing them and pharmaceutical compositions in which they are present
US6248752B1 (en) 1998-02-27 2001-06-19 Charles Duane Smith Azabicyclooctane compositions and methods for enhancing chemotherapy
US6262066B1 (en) 1998-07-27 2001-07-17 Schering Corporation High affinity ligands for nociceptin receptor ORL-1
ES2165768B1 (en) 1999-07-14 2003-04-01 Almirall Prodesfarma Sa New quinuclidine derivatives and pharmaceutical compositions containing them.
EP1302458A4 (en) * 2000-07-11 2005-10-19 Banyu Pharma Co Ltd Ester derivatives
WO2004091482A3 (en) 2003-04-07 2004-12-23 Glaxo Group Ltd M3 muscarinic acetylcholine receptor antagonists
CN1897947A (en) 2003-10-17 2007-01-17 葛兰素集团有限公司 Muscarinic acetylcholine receptor antagonists field of the invention
US7345060B2 (en) 2003-11-21 2008-03-18 Theravance, Inc. Compounds having β2 adrenergic receptor agonist and muscarinic receptor antagonist activity
JP2007529511A (en) 2004-03-17 2007-10-25 グラクソ グループ リミテッドGlaxo Group Limited M3 muscarinic acetylcholine receptor antagonist
US20070185088A1 (en) 2004-03-17 2007-08-09 Jakob Busch-Petersen M3 muscarinic acetylchoine receptor antagonists
US7384946B2 (en) 2004-03-17 2008-06-10 Glaxo Group Limited M3 muscarinic acetylcholine receptor antagonists
EP1725240A4 (en) 2004-03-17 2009-03-25 Glaxo Group Ltd Muscarinic acetylcholine receptor antagonists
WO2005112644A3 (en) 2004-05-13 2006-03-30 Glaxo Group Ltd Muscarinic acetylcholine receptor antagonists
JP2008501020A (en) 2004-05-28 2008-01-17 グラクソ グループ リミテッドGlaxo Group Limited Muscarinic acetylcholine receptor antagonist
US20090258858A1 (en) 2004-10-29 2009-10-15 Jakob Busch-Petersen Muscarinic acetylcholine receptor antagonists
EP1957075A4 (en) 2004-11-15 2009-11-18 Glaxo Group Ltd Novel m3 muscarinic acetylcholine receptor antagonists
WO2006055503A3 (en) 2004-11-15 2006-08-03 Brian W Budzik Novel m3 muscarinic acetylcholine receptor antagonists
WO2006065755A3 (en) 2004-12-13 2006-10-12 Jakob Busch-Petersen Quaternary ammonium salts of fused hetearomatic amines as novel muscarinic acetylcholine receptor antagonists
WO2006065788A3 (en) 2004-12-13 2006-08-17 Glaxo Group Ltd Novel muscarinic acetylcholine receptor antagonists
WO2007018508A1 (en) 2005-07-28 2007-02-15 Glaxo Group Limited Novel m3 muscarinic acetycholine receptor antagonists
WO2007018514A1 (en) 2005-07-28 2007-02-15 Glaxo Group Limited Novel m3 muscarinic acetylcholine receptor antagonists
WO2007016650A3 (en) 2005-08-02 2007-05-31 Glaxo Group Ltd M3 muscarinic acetylcholine receptor antagonists
JP2009503099A (en) 2005-08-02 2009-01-29 グラクソ グループ リミテッドGlaxo Group Limited M3 muscarinic acetylcholine receptor antagonist
US7767691B2 (en) 2005-08-18 2010-08-03 Glaxo Group Limited Muscarinic acetylcholine receptor antagonists containing an azoniabiocyclo[2.2.1] heptane ring system

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2800478A (en) * 1955-07-01 1957-07-23 Smith Kline French Lab 3-substituted-8-alkylnortropanes and the acid and quaternary ammonium salts thereof

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
DATABASE CAOLD [Online] 1963 ZIRKLE, CH.L. ET AL.: '3-substituted tropane derivatives-(III) 3-substituted tropane carbinol, alkenes, and alkanes', XP002984395 Retrieved from STN Database accession no. (CA58:4510b) *
See also references of EP1648461A2 *

Also Published As

Publication number Publication date Type
RU2006104851A (en) 2006-06-27 application
WO2005009362A2 (en) 2005-02-03 application
EP1648461A4 (en) 2009-04-01 application
EP1648461A2 (en) 2006-04-26 application
CA2532433A1 (en) 2005-02-03 application
CN1822839A (en) 2006-08-23 application
JP2007525478A (en) 2007-09-06 application
US7495010B2 (en) 2009-02-24 grant
US20060178396A1 (en) 2006-08-10 application
KR20060054316A (en) 2006-05-22 application

Similar Documents

Publication Publication Date Title
GB2406691B (en) Voice reminder device
WO2006050477A3 (en) Anti-microbial compositions and methods of making and using the same
WO2004011611A3 (en) Taci antibodies and uses thereof
EP1416933B8 (en) Substituted piperidines as modulators of the melanocortin receptor
GB0225551D0 (en) Assay method
GB0223116D0 (en) Assay method

Legal Events

Date Code Title Description
AL Designated countries for regional patents

Kind code of ref document: A2

Designated state(s): GM KE LS MW MZ NA SD SL SZ TZ UG ZM ZW AM AZ BY KG KZ MD RU TJ TM AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IT LU MC NL PL PT RO SE SI SK TR BF BJ CF CG CI CM GA GN GQ GW ML MR NE SN TD TG

AK Designated states

Kind code of ref document: A2

Designated state(s): AE AG AL AM AT AU AZ BA BB BG BR BW BY BZ CA CH CN CO CR CU CZ DE DK DM DZ EC EE EG ES FI GB GD GE GH GM HR HU ID IL IN IS JP KE KG KP KR KZ LC LK LR LS LT LU LV MA MD MG MK MN MW MX MZ NA NI NO NZ OM PG PH PL PT RO RU SC SD SE SG SK SL SY TJ TM TN TR TT TZ UA UG US UZ VC VN YU ZA ZM ZW

121 Ep: the epo has been informed by wipo that ep was designated in this application
WWE Wipo information: entry into national phase

Ref document number: 172912

Country of ref document: IL

Ref document number: 2004259238

Country of ref document: AU

WWE Wipo information: entry into national phase

Ref document number: 12006500022

Country of ref document: PH

WWE Wipo information: entry into national phase

Ref document number: 06000506

Country of ref document: CO

Ref document number: 77/DELNP/2006

Country of ref document: IN

WWE Wipo information: entry into national phase

Ref document number: 200600167

Country of ref document: ZA

Ref document number: 2006/00167

Country of ref document: ZA

ENP Entry into the national phase in:

Ref document number: 2532433

Country of ref document: CA

WWE Wipo information: entry into national phase

Ref document number: 544692

Country of ref document: NZ

Ref document number: 1020067001001

Country of ref document: KR

ENP Entry into the national phase in:

Ref document number: 2006178396

Country of ref document: US

Kind code of ref document: A1

WWE Wipo information: entry into national phase

Ref document number: PA/a/2006/000663

Country of ref document: MX

Ref document number: 2006520387

Country of ref document: JP

Ref document number: 10565048

Country of ref document: US

ENP Entry into the national phase in:

Ref document number: 2004259238

Country of ref document: AU

Date of ref document: 20040716

Kind code of ref document: A

WWP Wipo information: published in national office

Ref document number: 2004259238

Country of ref document: AU

WWE Wipo information: entry into national phase

Ref document number: 2004778509

Country of ref document: EP

WWE Wipo information: entry into national phase

Ref document number: 1200600229

Country of ref document: VN

WWE Wipo information: entry into national phase

Ref document number: 2006104851

Country of ref document: RU

WWP Wipo information: published in national office

Ref document number: 2004778509

Country of ref document: EP

WWP Wipo information: published in national office

Ref document number: 1020067001001

Country of ref document: KR

WWP Wipo information: published in national office

Ref document number: 10565048

Country of ref document: US

ENP Entry into the national phase in:

Ref document number: PI0412537

Country of ref document: BR