WO2005009362A3 - Muscarinic acetylcholine receptor antagonists - Google Patents

Muscarinic acetylcholine receptor antagonists

Info

Publication number
WO2005009362A3
WO2005009362A3 PCT/US2004/023041 US2004023041W WO2005009362A3 WO 2005009362 A3 WO2005009362 A3 WO 2005009362A3 US 2004023041 W US2004023041 W US 2004023041W WO 2005009362 A3 WO2005009362 A3 WO 2005009362A3
Authority
WO
Grant status
Application
Patent type
Prior art keywords
receptor antagonists
acetylcholine receptor
muscarinic acetylcholine
muscarinic
methods
Prior art date
Application number
PCT/US2004/023041
Other languages
French (fr)
Other versions
WO2005009362A2 (en )
Inventor
Kristen E Belmonte
Jakob Busch-Petersen
Dramane Laine
Michael R Palovich
Original Assignee
Kristen E Belmonte
Jakob Busch-Petersen
Glaxo Group Ltd
Dramane Laine
Michael R Palovich
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D451/00Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof
    • C07D451/02Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof containing not further condensed 8-azabicyclo [3.2.1] octane or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane; Cyclic acetals thereof

Abstract

Muscarinic Acetylcholine Receptor Antagonists and methods of using them are provided.
PCT/US2004/023041 2003-07-17 2004-07-16 Muscarinic acetylcholine receptor antagonists WO2005009362A3 (en)

Priority Applications (2)

Application Number Priority Date Filing Date Title
US48798203 true 2003-07-17 2003-07-17
US60/487,982 2003-07-17

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
JP2006520387A JP2007525478A (en) 2003-07-17 2004-07-16 Muscarinic acetylcholine receptor antagonist
CA 2532433 CA2532433A1 (en) 2003-07-17 2004-07-16 Muscarinic acetylcholine receptor antagonists
US10565048 US7495010B2 (en) 2003-07-17 2004-07-16 Muscarinic acetylcholine receptor antagonists
EP20040778509 EP1648461A4 (en) 2003-07-17 2004-07-16 Muscarinic acetylcholine receptor antagonists

Publications (2)

Publication Number Publication Date
WO2005009362A2 true WO2005009362A2 (en) 2005-02-03
WO2005009362A3 true true WO2005009362A3 (en) 2005-04-07

Family

ID=34102736

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2004/023041 WO2005009362A3 (en) 2003-07-17 2004-07-16 Muscarinic acetylcholine receptor antagonists

Country Status (8)

Country Link
US (1) US7495010B2 (en)
EP (1) EP1648461A4 (en)
JP (1) JP2007525478A (en)
KR (1) KR20060054316A (en)
CN (1) CN1822839A (en)
CA (1) CA2532433A1 (en)
RU (1) RU2006104851A (en)
WO (1) WO2005009362A3 (en)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE602004030930D1 (en) * 2003-10-14 2011-02-17 Glaxo Group Ltd Muscarinic acetylcholine receptor antagonists
CA2542636A1 (en) * 2003-10-17 2005-04-28 Glaxo Group Limited Muscarinic acetylcholine receptor antagonists field of the invention
ES2390458T3 (en) 2003-11-04 2012-11-13 Glaxo Group Limited Muscarinic antagonists acetylcholine M3 receptor
EP1725236A4 (en) * 2004-03-11 2009-05-13 Glaxo Group Ltd Novel m3 muscarinic acetylcholine receptor antagonists
EP1725564A4 (en) * 2004-03-17 2007-09-12 Glaxo Group Ltd M3 muscarinic acetylcholine receptor antagonists
US20070185148A1 (en) * 2004-03-17 2007-08-09 Glaxo Group Limited M3 muscarinic acetylchoine receptor antagonists
CA2755954C (en) 2004-04-27 2014-02-18 Glaxo Group Limited Quaternary quinuclidine derivatives and their use as muscarinic receptor antagonists
WO2005112644A3 (en) * 2004-05-13 2006-03-30 Glaxo Group Ltd Muscarinic acetylcholine receptor antagonists
EP1957075A4 (en) * 2004-11-15 2009-11-18 Glaxo Group Ltd Novel m3 muscarinic acetylcholine receptor antagonists
JP2009503099A (en) * 2005-08-02 2009-01-29 グラクソ グループ リミテッドGlaxo Group Limited M3 muscarinic acetylcholine receptor antagonist
US7767691B2 (en) * 2005-08-18 2010-08-03 Glaxo Group Limited Muscarinic acetylcholine receptor antagonists containing an azoniabiocyclo[2.2.1] heptane ring system
JP2011511084A (en) 2008-02-06 2011-04-07 グラクソ グループ リミテッドGlaxo Group Limited Double pharmacophore -pde4- muscarinic antagonist
CN101990401A (en) 2008-02-06 2011-03-23 葛兰素集团有限公司 Dual pharmacophores - pde4-muscarinic antagonistics
KR20100125295A (en) 2008-02-06 2010-11-30 글락소 그룹 리미티드 Dual pharmacophores - pde4-muscarinic antagonistics
WO2010094643A1 (en) 2009-02-17 2010-08-26 Glaxo Group Limited Quinoline derivatives and their uses for rhinitis and urticaria
EP3248970A1 (en) 2016-05-27 2017-11-29 Zentiva K.S. Forms of umeclidinium bromide

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RU2006104854A (en) 2003-07-17 2006-06-27 Глэксо Груп Лимитед (GB) Antagonists of muscarinic acetylcholine receptors
WO2005009439A1 (en) 2003-07-17 2005-02-03 Glaxo Group Limited Muscarinic acetylcholine receptor antagonists
DE602004030930D1 (en) 2003-10-14 2011-02-17 Glaxo Group Ltd Muscarinic acetylcholine receptor antagonists
CA2542636A1 (en) 2003-10-17 2005-04-28 Glaxo Group Limited Muscarinic acetylcholine receptor antagonists field of the invention
ES2390458T3 (en) 2003-11-04 2012-11-13 Glaxo Group Limited Muscarinic antagonists acetylcholine M3 receptor
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US20070185148A1 (en) 2004-03-17 2007-08-09 Glaxo Group Limited M3 muscarinic acetylchoine receptor antagonists
US20070185088A1 (en) 2004-03-17 2007-08-09 Jakob Busch-Petersen M3 muscarinic acetylchoine receptor antagonists
EP1725564A4 (en) 2004-03-17 2007-09-12 Glaxo Group Ltd M3 muscarinic acetylcholine receptor antagonists
EP1725240A4 (en) 2004-03-17 2009-03-25 Glaxo Group Ltd Muscarinic acetylcholine receptor antagonists
CA2755954C (en) 2004-04-27 2014-02-18 Glaxo Group Limited Quaternary quinuclidine derivatives and their use as muscarinic receptor antagonists
WO2005112644A3 (en) 2004-05-13 2006-03-30 Glaxo Group Ltd Muscarinic acetylcholine receptor antagonists
JP2008501020A (en) 2004-05-28 2008-01-17 グラクソ グループ リミテッドGlaxo Group Limited Muscarinic acetylcholine receptor antagonist
US20090258858A1 (en) 2004-10-29 2009-10-15 Jakob Busch-Petersen Muscarinic acetylcholine receptor antagonists
EP1957075A4 (en) 2004-11-15 2009-11-18 Glaxo Group Ltd Novel m3 muscarinic acetylcholine receptor antagonists
WO2006055503A3 (en) 2004-11-15 2006-08-03 Brian W Budzik Novel m3 muscarinic acetylcholine receptor antagonists
WO2006062883A3 (en) 2004-12-06 2007-03-29 Dramane Ibrahim Laine Medical combinations
WO2006062931A3 (en) 2004-12-06 2007-04-19 Smithkline Beecham Corp Medical combinations
WO2006065755A3 (en) 2004-12-13 2006-10-12 Jakob Busch-Petersen Quaternary ammonium salts of fused hetearomatic amines as novel muscarinic acetylcholine receptor antagonists
WO2006065788A3 (en) 2004-12-13 2006-08-17 Glaxo Group Ltd Novel muscarinic acetylcholine receptor antagonists
WO2007018508A1 (en) 2005-07-28 2007-02-15 Glaxo Group Limited Novel m3 muscarinic acetycholine receptor antagonists
WO2007018514A1 (en) 2005-07-28 2007-02-15 Glaxo Group Limited Novel m3 muscarinic acetylcholine receptor antagonists
WO2007016650A3 (en) 2005-08-02 2007-05-31 Glaxo Group Ltd M3 muscarinic acetylcholine receptor antagonists
JP2009503099A (en) 2005-08-02 2009-01-29 グラクソ グループ リミテッドGlaxo Group Limited M3 muscarinic acetylcholine receptor antagonist
US7767691B2 (en) 2005-08-18 2010-08-03 Glaxo Group Limited Muscarinic acetylcholine receptor antagonists containing an azoniabiocyclo[2.2.1] heptane ring system

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2800478A (en) * 1955-07-01 1957-07-23 Smith Kline French Lab 3-substituted-8-alkylnortropanes and the acid and quaternary ammonium salts thereof

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
DATABASE CAOLD [Online] 1963 ZIRKLE, CH.L. ET AL.: '3-substituted tropane derivatives-(III) 3-substituted tropane carbinol, alkenes, and alkanes', XP002984395 Retrieved from STN Database accession no. (CA58:4510b) *
See also references of EP1648461A2 *

Also Published As

Publication number Publication date Type
RU2006104851A (en) 2006-06-27 application
WO2005009362A2 (en) 2005-02-03 application
EP1648461A4 (en) 2009-04-01 application
EP1648461A2 (en) 2006-04-26 application
CA2532433A1 (en) 2005-02-03 application
CN1822839A (en) 2006-08-23 application
JP2007525478A (en) 2007-09-06 application
US7495010B2 (en) 2009-02-24 grant
US20060178396A1 (en) 2006-08-10 application
KR20060054316A (en) 2006-05-22 application

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