WO2005007150A3 - Method for inhibiting protein synthesis in sperm - Google Patents
Method for inhibiting protein synthesis in sperm Download PDFInfo
- Publication number
- WO2005007150A3 WO2005007150A3 PCT/IL2004/000648 IL2004000648W WO2005007150A3 WO 2005007150 A3 WO2005007150 A3 WO 2005007150A3 IL 2004000648 W IL2004000648 W IL 2004000648W WO 2005007150 A3 WO2005007150 A3 WO 2005007150A3
- Authority
- WO
- WIPO (PCT)
- Prior art keywords
- sperm
- mrna
- inhibiting
- substance
- pharmaceutical composition
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/16—Amides, e.g. hydroxamic acids
- A61K31/165—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/65—Tetracyclines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7008—Compounds having an amino group directly attached to a carbon atom of the saccharide radical, e.g. D-galactosamine, ranimustine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7088—Compounds having three or more nucleosides or nucleotides
- A61K31/711—Natural deoxyribonucleic acids, i.e. containing only 2'-deoxyriboses attached to adenine, guanine, cytosine or thymine and having 3'-5' phosphodiester links
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7088—Compounds having three or more nucleosides or nucleotides
- A61K31/7125—Nucleic acids or oligonucleotides having modified internucleoside linkage, i.e. other than 3'-5' phosphodiesters
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7088—Compounds having three or more nucleosides or nucleotides
- A61K31/713—Double-stranded nucleic acids or oligonucleotides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/16—Masculine contraceptives
Abstract
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US48760603P | 2003-07-17 | 2003-07-17 | |
US60/487,606 | 2003-07-17 |
Publications (2)
Publication Number | Publication Date |
---|---|
WO2005007150A2 WO2005007150A2 (en) | 2005-01-27 |
WO2005007150A3 true WO2005007150A3 (en) | 2005-08-04 |
Family
ID=34079385
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PCT/IL2004/000648 WO2005007150A2 (en) | 2003-07-17 | 2004-07-18 | Method for inhibiting protein synthesis in sperm |
Country Status (1)
Country | Link |
---|---|
WO (1) | WO2005007150A2 (en) |
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US9227956B2 (en) | 2013-04-17 | 2016-01-05 | Pfizer Inc. | Substituted amide compounds |
Families Citing this family (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP3124046B1 (en) | 2007-07-12 | 2019-12-25 | GITR, Inc. | Combination therapies employing gitr binding molecules |
US11273167B2 (en) | 2015-08-03 | 2022-03-15 | The Regents Of The University Of California | Compositions and methods for modulating ABHD2 activity |
JOP20190100A1 (en) | 2016-11-19 | 2019-05-01 | Potenza Therapeutics Inc | Anti-gitr antigen-binding proteins and methods of use thereof |
Citations (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5976893A (en) * | 1994-06-02 | 1999-11-02 | Mount Sinai Hospital | Methods for identifying binding partners, agonists, and antagonist of a serine/threonine tyrosine kinase |
WO2001066084A2 (en) * | 2000-03-07 | 2001-09-13 | Rush-Presbyterian-St. Luke's Medical Center | Compositions and methods for trapping and inactivating pathogenic microbes and spermatozoa |
US20020164368A1 (en) * | 2000-12-18 | 2002-11-07 | Ronald Zimmerman | Male contraceptive method and composition |
WO2002090567A2 (en) * | 2001-05-03 | 2002-11-14 | Children's Medical Center, Corporation | Sperm-specific cation channel, and uses therefor |
-
2004
- 2004-07-18 WO PCT/IL2004/000648 patent/WO2005007150A2/en active Application Filing
Patent Citations (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5976893A (en) * | 1994-06-02 | 1999-11-02 | Mount Sinai Hospital | Methods for identifying binding partners, agonists, and antagonist of a serine/threonine tyrosine kinase |
WO2001066084A2 (en) * | 2000-03-07 | 2001-09-13 | Rush-Presbyterian-St. Luke's Medical Center | Compositions and methods for trapping and inactivating pathogenic microbes and spermatozoa |
US20020164368A1 (en) * | 2000-12-18 | 2002-11-07 | Ronald Zimmerman | Male contraceptive method and composition |
WO2002090567A2 (en) * | 2001-05-03 | 2002-11-14 | Children's Medical Center, Corporation | Sperm-specific cation channel, and uses therefor |
Non-Patent Citations (5)
Title |
---|
BRAGG P W ET AL: "PROTEIN SYNTHESIS IN MOUSE SPERMATOZOA", BIOLOGY OF REPRODUCTION, vol. 20, no. 2, 1979, pages 333 - 337, XP008038706, ISSN: 0006-3363 * |
DOKOV V K ET AL: "[Arrest of spermatogenesis by various antibiotics: preliminary experimental results]", ACTA UROLOGICA BELGICA. JUL 1970, vol. 38, no. 3, July 1970 (1970-07-01), pages 277 - 287, XP008038737, ISSN: 0001-7183 * |
GUR YAEL ET AL: "Protein translation in mammalian sperm.", BIOLOGY OF REPRODUCTION, vol. 68, no. Supplement 1, 2003, & THIRTY-SIXTH ANNUAL MEETING OF THE SOCIETY FOR THE STUDY OF REPRODUCTION; CINCINNATI, OH, USA; JULY 19-22, 2003, pages 295, XP008038696, ISSN: 0006-3363 * |
HUWE PETRA ET AL: "Influence of antibiotics on sperm motility: An in vitro experiment", EUROPEAN UROLOGY, vol. 39, no. Suppl. 5, March 2001 (2001-03-01), & XVITH CONGRESS OF THE EUROPEAN ASSOCIATION OF UROLOGY; GENEVA, SWITZERLAND; APRIL 07-10, 2001, pages 132, XP008038694, ISSN: 0302-2838 * |
SCHILL W B: "Problems of anticonception in the male. I. Physiologic basis; mechanical and pharmacologic methods", FORTSCHRITTE DER MEDIZIN 1978 GERMANY, vol. 96, no. 29, 1978, pages 1447 - 1451, XP008038757 * |
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US9227956B2 (en) | 2013-04-17 | 2016-01-05 | Pfizer Inc. | Substituted amide compounds |
Also Published As
Publication number | Publication date |
---|---|
WO2005007150A2 (en) | 2005-01-27 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
BRPI0410731A (en) | compound, pharmaceutical composition, methods for agonizing the mc4 receptor, treating obesity, treating diabetes mellitus and treating male and / or female sexual dysfunction in a mammal, and, using a compound | |
PL1828297T3 (en) | Preparation and treatment of bituminous compositions | |
TW200716134A (en) | Tricyclic opioid modulators | |
BR0312975A (en) | Crystalline form of ß2 adrenergic receptor agonist | |
AP1542A (en) | Glucocorticoid receptor modulators. | |
WO2006069276A3 (en) | TRICYCLIC ō-OPIOID MODULATORS | |
MX2007007220A (en) | Pyrazolone compounds as metabotropic glutamate receptor agonists for the treatment of neurological and psychiatric disorders. | |
WO2005121065A3 (en) | DIAMINE β2 ADRENERGIC RECEPTOR AGONISTS | |
EP1372653A4 (en) | Acylated piperidine derivatives as melanocortin-4 receptor agonists | |
MX2007004936A (en) | Compounds and compositions as inhibitors of cannabinoid receptor 1 activity. | |
DE59303142D1 (en) | Sweeteners, process for making the same and its use | |
MY156341A (en) | Hydrogenolysis of sugar feedstock | |
PT1254146E (en) | CLARITROMYCINE POLYMER PREPARATION PROCESSES AND NEW POLYMORPH IV | |
WO2005030678A3 (en) | AMINO-SUBSTITUTED ETHYLAMINO β2 ADRENERGIC RECEPTOR AGONISTS | |
MXPA06003363A (en) | Phenyl-piperazine derivatives as modulators of muscarinic receptors. | |
WO2004017961A3 (en) | Derivatives of 3-hydroxy-4-(cyclyl-alkylaminoalkyl)-5-phenyl-1h-pyrazole as antagonists of the gonadotropin releasing hormone (gnrh) for use in the treatment of sex hormone related conditions, such as prostatic of uterine cancer | |
WO2006096405A3 (en) | Treatment of amyotrophic lateral sclerosis with pyrimethamine and analogues | |
MX2009001966A (en) | Method of reducing neuronal cell damage. | |
WO2005007150A3 (en) | Method for inhibiting protein synthesis in sperm | |
AR008621A1 (en) | A COMPOUND DERIVED FROM SUCCINIC AMINE, A PROCEDURE FOR CARRYING OUT ITS PREPARATION AND A PHARMACEUTICAL COMPOSITION INCLUDING SUCH A COMPOSITION | |
WO2006074388A3 (en) | TRICYCLIC δ-OPIOID MODULATORS | |
EP1262196A3 (en) | Combination of a monoamine reuptake inhibitor and an opioid antagonist for use in alcoholism and alcohol dependence | |
MX2007007627A (en) | Tricyclic o-opioid modulators. | |
ES2178209T3 (en) | PROCEDURE TO PREPARE AN ASPHALT COMPOSITION. | |
WO2004078103A3 (en) | G-lactam derivatives as prostaglandin agonists |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
AK | Designated states |
Kind code of ref document: A2 Designated state(s): AE AG AL AM AT AU AZ BA BB BG BR BW BY BZ CA CH CN CO CR CU CZ DE DK DM DZ EC EE EG ES FI GB GD GE GH GM HR HU ID IL IN IS JP KE KG KP KR KZ LC LK LR LS LT LU LV MA MD MG MK MN MW MX MZ NA NI NO NZ OM PG PH PL PT RO RU SC SD SE SG SK SL SY TJ TM TN TR TT TZ UA UG US UZ VC VN YU ZA ZM ZW |
|
AL | Designated countries for regional patents |
Kind code of ref document: A2 Designated state(s): BW GH GM KE LS MW MZ NA SD SL SZ TZ UG ZM ZW AM AZ BY KG KZ MD RU TJ TM AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IT LU MC NL PL PT RO SE SI SK TR BF BJ CF CG CI CM GA GN GQ GW ML MR NE SN TD TG |
|
121 | Ep: the epo has been informed by wipo that ep was designated in this application | ||
122 | Ep: pct application non-entry in european phase |