WO2005002652A2 - Vorrichtung zur verabreichung eines flüssigen produkts - Google Patents
Vorrichtung zur verabreichung eines flüssigen produkts Download PDFInfo
- Publication number
- WO2005002652A2 WO2005002652A2 PCT/EP2004/006846 EP2004006846W WO2005002652A2 WO 2005002652 A2 WO2005002652 A2 WO 2005002652A2 EP 2004006846 W EP2004006846 W EP 2004006846W WO 2005002652 A2 WO2005002652 A2 WO 2005002652A2
- Authority
- WO
- WIPO (PCT)
- Prior art keywords
- piston plug
- output member
- piston
- connecting mechanism
- hook elements
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/14—Infusion devices, e.g. infusing by gravity; Blood infusion; Accessories therefor
- A61M5/142—Pressure infusion, e.g. using pumps
- A61M5/145—Pressure infusion, e.g. using pumps using pressurised reservoirs, e.g. pressurised by means of pistons
- A61M5/1452—Pressure infusion, e.g. using pumps using pressurised reservoirs, e.g. pressurised by means of pistons pressurised by means of pistons
- A61M5/14566—Pressure infusion, e.g. using pumps using pressurised reservoirs, e.g. pressurised by means of pistons pressurised by means of pistons with a replaceable reservoir for receiving a piston rod of the pump
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
- A61M5/31—Details
- A61M5/315—Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
- A61M5/31511—Piston or piston-rod constructions, e.g. connection of piston with piston-rod
- A61M5/31515—Connection of piston with piston rod
Definitions
- the invention relates to a device for the preferably metered administration of a liquid and preferably containing a medicinal or therapeutic active ingredient, very particularly preferably for the administration of insulin for the treatment of diabetes patients.
- liquids which contain a medical or therapeutic active substance are preferably stored in a fluid container in which a piston stopper is mounted so as to be axially displaceable.
- the piston plug is axially displaced by an output member of a drive mechanism toward an outlet of the fluid container in order to cause fluid to be released from the fluid container.
- the fluid container is interchangeable. This requires a connection mechanism for releasably connecting the piston plug to the output member.
- connection mechanism should be designed in such a way that the connection between the piston plug and the output member is blocked against axial displacement of the output member relative to the piston plug, in order to prevent, for example, self-emptying of the fluid container due to the so-called siphoning effect.
- the object of the invention is to provide a device for the preferably metered administration of a product with a connecting mechanism which is designed in such a way that the connection between the piston plug and the output member can be easily established and released again.
- the connecting mechanism is designed such that the connection between the piston plug and the driven member is moved towards the piston plug by axially advancing the driven member can be produced. It is advantageous that the drive mechanism of the injection or infusion device in which the fluid container is to be used does not need to be specially designed for the exchange of the fluid container. Rather, the axial feed movement of the driven member, for which the mechanics of the injection or infusion device is designed anyway, can also be used at the same time to establish the connection between the piston plug and the driven member.
- a suitable mechanical connection between the piston plug and the output member which is sufficiently stable for an exact dosage of the fluid dose administered.
- a mechanical connection are a locking, a latching or a snap connection.
- the driven member When the driven member is pushed axially towards the piston plug, the driven member is preferably not rotated. A simultaneous rotation of the driven member during the axial advancement can, however, in principle be permissible according to the invention in order to produce the connection.
- the output member itself or a front end of the output member is preferably pushed into the piston plug to establish the connection and / or the piston plug is pushed over the output member by insertion.
- means for establishing the mechanical connection are provided on the output member, preferably at its front end, for example suitable locking, latching or snap means.
- These means are received in the piston stopper by correspondingly designed elements, for example by correspondingly designed locking, latching or snap-in means, which can be formed in particular by the threads of conventional piston stopper.
- the output member can be advanced substantially unimpeded to establish the mechanical connection without exerting any significant driving force on the piston plug.
- the connection is brought about by inserting the fluid container. It is advantageous that no unintentional propelling force is exerted on the piston plug when the mechanical connection is established, which would cause an unintentional release of fluid.
- the connecting mechanism is designed to be flexible, so that the elements of the connecting mechanism which bring about the mechanical connection are flexible when the driven member is advanced axially and / or are resilient and / or not locked as long as the mechanical connection, for example by locking, latching or snapping, has not yet been established, so that the elements of the connecting mechanism which bring about the mechanical connection, however, after the mechanical connection has been established, prevent it from being adjusted axially lock the output member relative to the piston plug.
- the device is provided with a device by means of which the driven member for moving the connection to the piston plug is moved in the direction of advance, preferably by motor.
- the device further comprises a device which detects when the driven member and the piston plug are correctly connected to one another and preferably also when the driven member is locked to the piston plug.
- a detection device can in particular comprise a sensor for measuring an axial force or a torque which acts on the output element. The point in time at which the driven member is correctly positioned in the piston plug is signaled by a change in the axial force or the torque measured by the sensor.
- the change in the measured variable for example the axial force or the torque, can vary from the wall friction between the piston stopper and the fluid container and / or the flow resistance to the outlet of the The fluid container connecting catheter.
- the evaluation of the flow resistance requires a catheter. However, this is not a disadvantage since the catheter has to be filled with the fluid after the fluid container has been inserted. It can be used here that the change in the measured variable also increases with the increase in the axial speed which the output element and the piston plug have to produce the connection relative to one another and can thus be detected more easily and reliably.
- the connecting mechanism preferably comprises a number of hooks, preferably a number of resilient hooks, which are designed to give way essentially in the radial direction when the driven member is pushed axially onto the piston plug or the axial movement of the fluid container in the direction of the driven member, and then again radially spread to effect the locking against axial displacement of the output member relative to the piston plug by engaging in at least one undercut which is rigidly coupled to the piston plug and is preferably formed in one piece with the piston plug. Since flexible hooks can be produced in a simple and inexpensive manner, a simple and inexpensive connecting mechanism can be created according to the invention.
- the undercut is preferably provided in the rear side of the piston plug facing the driven member, preferably in a cavity of the piston plug, and has a suitable profile which is matched to the type of elements producing the mechanical connection and their geometry.
- the undercut of the connecting mechanism is preferably designed in the form of a helical thread, with a direction of rotation that corresponds to the direction of rotation in which the mechanical connection is to be released by twisting.
- the helical thread preferably extends over several revolutions, the thread height being adapted to the shape of the elements that produce the mechanical connection.
- the connection mechanism comprises a plurality of hooks which are arranged distributed on the outer circumferential surface and project radially therefrom, the hooks preferably also being arranged distributed along the longitudinal axis of the output member.
- the hooks can be grouped into several rings, which are distributed at different positions along the longitudinal axis of the driven member and each comprise a plurality of hooks.
- the hooks can also be arranged randomly with respect to their axial position and angular position.
- the number of hooks is preferably so large that a plurality of the hooks each act as barbs and the plurality of barbs in the connected state press against the direction of advance of the piston plug against one or preferably several undercuts of the piston plug.
- the output member has a stop against which, when the mechanical connection is established, the back of the piston stopper bears directly. It is advantageous that the piston stopper cannot move in the axial direction during the axial advancement towards the outlet of the fluid container, so that the fluid dose specified by the drive mechanism of the injection or infusion device can be administered precisely.
- the aforementioned hooks or the one or more elements producing the mechanical connection are preferably arranged in the axial direction before the output member stops.
- the hooks of the connecting mechanism are preferably essentially pivotable or bendable in the radial direction, and preferably without a greater application of force being required for this. In this way it is ensured that when the driven member is axially advanced toward the piston plug or the Insertion movement of the container essentially no driving force is exerted on the plunger stopper, so that no product is released unintentionally.
- the hooks are designed as elastic elements and made of a suitable material, for example plastic or metal, of suitable strength.
- Such elastic elements can be easily molded onto the front end of the output member, in particular integrally molded, or attached and make an additional and complex mechanism unnecessary, which would otherwise have to be provided in order to make the elastic elements pivotable or flexible. They are particularly preferably flexible and act as bending beams firmly clamped on one side.
- the elastic elements of the use mechanism rotate at least slightly when the output member is rotated relative to the piston, i.e. they yield slightly elastically in the circumferential direction, so that the releasing of the connecting mechanism is only countered by a relatively small and thus negligible resistance force.
- the hooks of the connecting mechanism are designed as resilient claws which are held at a front end of the output member.
- the claws are designed so that they can engage in an opposite undercut in order to produce the mechanical connection between the output member and the piston plug.
- the claws are preferably essentially radially pivotable between a blocking position in which a further pivoting of the claws is blocked and which serves to block the mechanical connection, and a release position in which the claws are pivoted radially back at least to such an extent that the output member in can be pushed towards or into the piston plug essentially without resistance.
- the resilient claws are preferably held on guide and fastening elements in such a way that the claws are guided in a straight line against rotation during the pivoting movement and so are prevented from yielding in the circumferential direction.
- the claws thus do not deflect during their engagement in the undercut by executing a rotary movement, so that the mechanical connection between the piston plug and the output member can be achieved in an even more stable manner.
- the connecting mechanism preferably further comprises a resetting means which prestresses the resilient claws against one another and in a radially directed manner.
- a resetting means which prestresses the resilient claws against one another and in a radially directed manner.
- connection mechanism is designed in such a way that the claws can be adjusted radially in a motor-driven manner, for example with the aid of a spindle drive, in order to establish the mechanical connection between the output member and the piston plug.
- the moment at which the mechanical connection is established can thus be specified more precisely.
- FIG. 1 shows a cross section through a connecting mechanism and an infusion pump and a perspective view of the front end of an output member according to a first embodiment of the present invention.
- FIG. 2 shows a cross section through a connection mechanism and an infusion pump and a perspective view of the front end of an output member according to a second embodiment of the present invention
- Fig. 3 shows a cross section through a connecting mechanism and an infusion pump and a perspective view of the front end an output member according to a third embodiment of the present invention
- FIG. 4 shows two cross-sectional views of an infusion pump and a perspective view of the front end of an output member according to a fourth embodiment of the present invention, just before the connection between the plunger plug and the output member is achieved;
- FIG 5 shows two cross-sectional views of the infusion pump according to the fourth embodiment of the present invention after the connection between the plunger stopper and the output member has been established.
- FIG. 1 shows in the left part a cross section of an infusion pump according to a first embodiment of the present invention.
- the upper part of FIG. 1 shows in an enlarged cross section the connection mechanism according to this embodiment, the right part finally shows in a perspective view the front end of the output member according to this embodiment.
- the infusion pump 1 is used, for example, for the long-term administration of microdoses of a liquid stored in an ampoule 7, which contains a medical or therapeutic active ingredient, preferably insulin.
- the infusion pump 1 has a housing 2 which is essentially rectangular in cross section, in the interior 3 of which a mechanism and electronics (not shown) for controlling the pump are accommodated.
- a mechanism and electronics for controlling the pump are accommodated.
- the essentially cylindrical ampoule 7 which is accommodated in a housing section 8 which corresponds to the ampoule 7.
- a piston plug 6 is mounted in the ampoule 7 and is axially displaceable.
- the piston plug 6 is mechanically connected to the piston rod 4, which serves as an output member of the drive device, which is only shown schematically, for axially advancing the piston rod 4 and the piston plug 6.
- the piston rod 4 is straight in the lower part of the housing 2 and is in threaded engagement with a rotationally driven drive member 5. If the drive member 5 is driven in rotation, preferably by an electric motor, the piston days 4 are displaced axially linearly.
- the piston rod 4 pushes the piston stopper 6 towards the outlet 9.
- the ampoule 7 is mounted exchangeably in the housing section 8. To replace the ampoule 7, the connection between the piston rod 4 and the piston plug 6 must be released. At the same time, with regard to an exact dosing of the product, there is a need for the connection between the piston plug 6 and the piston rod 4 to be blocked against axial displacement or displacement of the piston rod 4 relative to the piston plug 6.
- connection between piston plug 6 and piston rod 4 can be released by relative rotation between piston plug 6 and piston rod 4, and the connection can be established by pushing the piston rod 4 towards or into the piston plug 6.
- the connection can be brought about by the opposite movement of the ampoule 7 when it is inserted.
- the front end of the piston rod 4 serving as the output member has a number of spring-elastic or at least spring-elastic mounted hooks 13 which jumped in the axial direction before the circumferential stop serving as a stopper for the piston plug 6 are arranged.
- the hooks 13 are formed in the manner of flexible bristles of a brush and protrude obliquely backwards from the piston rod 4 at an acute angle to the axial, so as to form thin elastic bending beams firmly clamped at their front ends.
- the resilient hooks 13 are combined to form a plurality of rings, in the example shown to a total of five rings, the hooks 13 of a respective ring being arranged approximately at the same axial height and the hooks 13 of the different rings being aligned in the axial direction.
- the resilient hook 13 can also be of a different type or disordered be arranged in the manner of a curling brush at the front end of the piston rod 4.
- the resilient hooks 13 consist of a resilient material, for example of a plastic or a metal of low strength, so that the hooks 13 when the force is applied radially inwards, for example by contact with the undercut 15, by bending at the base thereof and / or over the whole thereof Giving length essentially in the radial direction and straightening up again after releasing the force.
- FIG. 1 shows the rear end of the ampoule 7 in a greatly enlarged cross section
- the piston plug 6 On its rear side, the piston plug 6 has a helical thread 14, the thread 14 in the axial direction in each longitudinal section successively forming a plurality of undercuts 15 on which the resilient hooks 13 lock the axial position of the piston 6 relative to the piston rod 4 Support against the direction of advance.
- the resilient hooks 13 Only a part of the resilient hooks 13 is supported in the associated undercut 15 against the direction of advance, while another part of the hooks 13 is not completely erected again, i.e. is not yet spread out radially outward into the relaxed position.
- the procedure is as follows: The ampoule 7 is delivered in the rear end position shown in the upper part of FIG. 1, in which the rear side of the piston stopper 6 abuts or almost abuts the peripheral projection 10. After removing a used ampoule 7, the piston rod 4 is axially returned to a rear end position. The new ampoule 7 is then inserted into the housing section 8 until finally the front end of the piston rod 4 with the resilient Hook 13 is inserted into the piston plug 6. From the undercuts 15, the resilient hooks 13 are bent radially inward against their elastic restoring force.
- connection shown can, as described, be brought about by axially advancing only the piston rod 4 or only by inserting the ampoule 7 or, although less preferred, by a superimposed movement. This should not rule out that a relative rotation between piston plug 6 and piston rod 4 may also be permissible when the piston rod 4 is advanced.
- the piston plug 6 and the piston rod 4 cannot be pushed further against one another, since the piston plug 4 abuts the stop 10. Furthermore, the piston plug 6 cannot be advanced axially relative to the piston rod 4 because part of the resilient hook 13 is supported on the piston plug 6 against the direction of advance. Thus, the piston plug 6 is essentially rigidly connected to the piston rod 4.
- the piston plug 6 To release the connection shown, the piston plug 6 must be rotated relative to the piston rod 4, specifically against the course of the screw thread 14, so that the resilient hooks 13 are unscrewed from the thread. For loosening, the hooks 13 form the counter thread for the thread 14 of the piston plug 6, which forms the rear cuts 15.
- the resilient hook 13 need not be distributed around the entire circumference of the front end of the piston rod 4. Rather, the resilient hooks 13 can also be arranged concentrated in special angular ranges, for example at two diametrically opposite positions. In such an alternative embodiment, a relative rotation of 90 degrees would be sufficient to detach the connection, if the connection was rotated by 90 degrees Angular position an axially extending groove or the like is provided, along which the resilient hooks 13 can be withdrawn from engagement with the piston plug 6.
- FIG. 2 shows an infusion pump according to a second embodiment of the present invention in a cross section and the front end of the piston rod 4 is shown in a perspective view.
- the second embodiment differs only in that several hook rings 18 are placed on the front end of the piston rod 4.
- the hook rings 18 each have a circular ring 19, from which the tab-like hooks 13 project radially outward.
- the hook rings 18 are pushed onto the front end of the piston rod 4, where they each snap into a latching circumferential projection 20.
- the hooks 13 yield elastically only in the area of the base of the hook, that is to say in the connection area between the hook 13 and the circular ring 19.
- the hook ring 18 is preferably produced by deep drawing a metal.
- connection between the piston plug 6 and the piston rod 4 is produced by axially advancing the front end of the piston rod 4 into the piston plug 6 or by the axial movement of the ampoule 7 immediately upon insertion. No relative rotation is required for this, but this is generally permitted. As in the first embodiment, the connection is released by relative rotation of the piston plug 6 relative to the piston rod 4.
- connection mechanism comprises a plurality of resilient hooks 13 which are formed at the front end of the piston rod 4.
- resilient hooks 13 which are formed at the front end of the piston rod 4.
- FIG. 3 shows in cross section an infusion pump according to a third embodiment of the present invention and in a perspective view the front end of a piston rod according to this embodiment.
- four claws 21 are arranged at the front end of the piston rod 4.
- a central support 22 projects from the front end of the piston rod 4 and a fastening and guiding device 23 with a corresponding number, i.e. around the support 22. in the illustrated embodiment four, from fastening and guide elements.
- the claws 21 are each pivotally mounted transversely to the axial by means of pins 27 of the fastening and guide device 23.
- the openings 30 shown are provided for mounting the claws 21.
- the fastening and guiding device 23 forms four star-shaped gaps 24 in which the claws 21 are guided in a straight line, so that the claws 21 are pivoted essentially only in axial planes around the pivot axes formed by the pins 27 without being able to be rotated in the process , so that the claws 21 do not yield in the circumferential direction when the connection is blocked.
- the four claws 21 are arranged in pairs at the same height and the two pairs are axially offset from one another.
- the claws 21 engage in the connection, like the hooks 13, in the helical thread 14 at different depths. This is shown in the upper part of FIG. 3, where the right claw 21 engages deeper in the undercut 15 than the left claw 21.
- two of the claws 21 are prestressed radially outwards with the aid of a compression spring 25 which serves as a restoring means and which can be made of elastic material as an elastomer ring or also of elastic form.
- the compression spring 25 is held on the carrier 22.
- the claws 21 thus project maximally radially from the front end of the piston rod in the relieved idle state 4 from.
- the claws 21, which slide over the tips of the thread 14 are pivoted radially inwards.
- at least one of the claws 21 straightens up again into an opposite undercut 15 due to the restoring force of the compression spring 25 in order to block the connecting mechanism.
- the thread 14 does not have to be completely circumferential in the third embodiment either. Rather, it is sufficient, but not preferred, if the thread 14 is formed only at sections where it lies opposite the claws 21 and is otherwise replaced by axially extending grooves or the like. Such grooves can be offset by 45 degrees relative to the claws 21 in the connecting position, so that the connection can be released again by simply turning the piston plug 6 and the piston rod 4 by 45 degrees.
- the thread 14 preferably runs continuously.
- the piston plug 6 with thread 14 can be a conventional piston plug, in particular with a thread 14 that is customary for this, i.e. the invention does not require any adjustment on the side of the piston plug, which applies to all other exemplary embodiments.
- the pivotable claws 21 are forcibly pivoted without the action of the undercuts 15 in order to establish the mechanical connection between the piston plug 6 and the output member 4.
- the piston rod 4 is formed in two parts and comprises a centrally arranged slide rod 4a and a threaded sleeve 4b, which surrounds the slide rod 4a and guides axially linear.
- the threaded sleeve 4b has an external thread over almost its entire axial length, which is interrupted by a straight guide over its axial length.
- the threaded sleeve 4b is in threaded engagement with its external thread with an internal thread of the drive member 5.
- the drive member 5 is driven by a motor, not shown.
- the threaded sleeve 4b is guided axially in a straight line by the housing 2. A drive rotation of the drive member 5 therefore causes the threaded sleeve 4b to advance.
- the slide rod 4a is accommodated in the threaded sleeve 4b in an axially slidable manner. Movement relative to the threaded sleeve 4b against the direction of advance is limited by a stop shoulder 31 which is formed at the front end of the slide rod 4a and with which the slide rod 4a is supported at the front end of the threaded sleeve 4b.
- the slide rod 4a In the position shown in FIG. 4, which the piston rod 4 emits when a full ampoule 7 is inserted, the slide rod 4a is also axially supported on the housing 8 with its rear end.
- the slide rod 4a projects with a head piece 33 and the stop shoulder 31 axially beyond the stop 10 of the threaded sleeve 4b and into the fastening and guide device 23 formed by the threaded sleeve 4b and which pivotally supports a plurality of claws 21.
- the guiding and fastening device 23 and the claws 21 are formed essentially like those of the third exemplary embodiment.
- the pins 27 again form the pivot axis for each of the claws 21.
- each of the claws 21 forms an outer leg 26 and an inner leg 28.
- the claws 21 are each approximately L-shaped, the respective pivot axis being arranged in the region of the intersection of the two legs 26 and 28 of the L-shape.
- a compression spring 32 is arranged between the cover 29, which is comparable to the cover of the third exemplary embodiment, and the respective inner leg 26 of each claw 21, ie one compression spring 32 per claw 21.
- the elastic spring forces of the compression springs 32 cause the claws 21 Spread radially outward about the pivot axes of the pins 27. Conversely, this means that in order to insert the slide rod 4a into the cavity of the piston plug 6, the compression springs 32 are forcibly compressed and the outer legs 26 are thereby pivoted radially inwards.
- Figure 4 shows the device in the state in which the legs 26 of the claws 21 are pivoted radially inward against the force of the respective compression spring 32.
- the slide rod 4a takes up its foremost axial position relative to the threaded sleeve 4b, in which the stop shoulder 31 is axially spaced a little from the front end of the threaded sleeve 4b.
- the head piece 33 presses like a plunger in the direction of advance against the inner legs 28 of the claws 21, so that the claws 21 are pivoted radially inward with their outer legs 26.
- the threaded sleeve 4b is axially supported on the housing 8 with its stop 10 against the direction of advance.
- the ampoule 7 is pushed into the housing 8 against the direction of advance until the piston stopper 6 seated at the rear end of the ampoule 7 is pushed onto the guide and fastening device 23. Sliding on is not impeded by the swung-in claws 26.
- the device is in the state shown in FIG. 4, in which the piston plug 6 is in stop contact with the stop 10 of the threaded sleeve 4b and / or the guide and fastening element 23 and the slide rod 4a against the direction of advance takes its axially foremost position relative to the threaded sleeve 4 b, in which its stop shoulder 31 is axially clear from the front end of the stop 10.
- the drive member 5 is driven in rotation, so that the threaded sleeve 4b translates in the direction of advance due to its straight guidance.
- its stop 10 lifts off the counter-abutment surface of the housing section 8 and the piston plug 6 seated on the stop 10 is moved together with the threaded sleeve 4b in the direction of advance.
- the tensioned compression springs 32 press the slide rod 4a over the claws 21 against the direction of advance.
- the compression springs 32 press with their elastic restoring forces onto the inner legs 28 of the claws 21, so that pivot the outer legs 26 radially outward about the pins 27.
- the pivoting process is ended when the claws 21 come to a stop to the rear surfaces of the undercuts 15 or the stop 10 comes into contact with the stop shoulder 31.
- Figure 5 shows the device in the state in which the connection between the piston rod 4 and the piston 6 is made. At least one of the four claws 21 is in abutment against a surface of the undercut 15 facing in the direction of advance, so that the piston rod 4 and the piston plug 6 are axially fixed to one another.
- the pivot axes of all the claws 21, in the exemplary embodiment four claws 21, are arranged axially at the same height.
- the undercuts 15, as in the other exemplary embodiments, are preferably formed by a thread which runs continuously in several revolutions.
- an adjusting device acts between the slide rod 4a and the threaded sleeve 4b.
- the adjusting device can be implemented, for example, by a magnetic coupling of the slide rod 4a and the threaded sleeve 4b by means of electromagnets.
- a purely mechanical adjusting device is also conceivable.
- connection mechanism has been described above in connection with a motor-driven infusion pump, the invention is not restricted to this. Rather, the connection mechanism can also be applied to injection devices in which the ampoule containing the product is to be exchanged.
- Gauge 30 or Gauge 31 hollow needles which are attached to the outlet of the fluid container.
Landscapes
- Health & Medical Sciences (AREA)
- Vascular Medicine (AREA)
- Engineering & Computer Science (AREA)
- Anesthesiology (AREA)
- Biomedical Technology (AREA)
- Heart & Thoracic Surgery (AREA)
- Hematology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Infusion, Injection, And Reservoir Apparatuses (AREA)
Abstract
Description
Claims
Priority Applications (4)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP2006518033A JP2009513167A (ja) | 2003-07-03 | 2004-06-24 | 液体製剤投与装置 |
CA002525797A CA2525797A1 (en) | 2003-07-03 | 2004-06-24 | Device for administering a liquid product |
EP04740259A EP1642094A2 (de) | 2003-07-03 | 2004-06-24 | Vorrichtung zur verabreichung eines flüssigen produkts |
US11/314,814 US7798377B2 (en) | 2003-07-03 | 2005-12-21 | Device for administering a liquid product |
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE10330094A DE10330094B4 (de) | 2003-07-03 | 2003-07-03 | Vorrichtung zur Verabreichung eines flüssigen Produkts |
DE10330094.5 | 2003-07-03 |
Related Child Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
US11/314,814 Continuation US7798377B2 (en) | 2003-07-03 | 2005-12-21 | Device for administering a liquid product |
Publications (2)
Publication Number | Publication Date |
---|---|
WO2005002652A2 true WO2005002652A2 (de) | 2005-01-13 |
WO2005002652A3 WO2005002652A3 (de) | 2005-08-18 |
Family
ID=33559853
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PCT/EP2004/006846 WO2005002652A2 (de) | 2003-07-03 | 2004-06-24 | Vorrichtung zur verabreichung eines flüssigen produkts |
Country Status (6)
Country | Link |
---|---|
US (1) | US7798377B2 (de) |
EP (1) | EP1642094A2 (de) |
JP (1) | JP2009513167A (de) |
CA (1) | CA2525797A1 (de) |
DE (1) | DE10330094B4 (de) |
WO (1) | WO2005002652A2 (de) |
Cited By (39)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2007118907A1 (en) | 2006-04-19 | 2007-10-25 | Novo Nordisk A/S | A fluid infusion system, a method of assembling such system and drug reservoir for use in the system |
WO2008103175A1 (en) * | 2007-02-22 | 2008-08-28 | M2 Group Holdings, Inc. | Portable infusion pump with flexible piston rod |
WO2008151241A2 (en) | 2007-06-04 | 2008-12-11 | Becton, Dickinson And Company | Stopper and plunger rod for a pre-filled syringe |
JP2009534073A (ja) * | 2006-04-19 | 2009-09-24 | ノボ・ノルデイスク・エー/エス | 流体注入システム、同システムの組み立て方法及び同システムで使用される薬剤容器 |
WO2010089310A1 (en) * | 2009-02-05 | 2010-08-12 | Sanofi-Aventis Deutschland Gmbh | Medicament delivery devices |
EP2510963A1 (de) * | 2011-04-15 | 2012-10-17 | F.Hoffmann-La Roche Ag | Vorrichtung zum Bewegen eines Kolbens in einer Kartusche |
WO2013135275A1 (en) | 2012-03-13 | 2013-09-19 | F. Hoffmann-La Roche Ag | Filling device and controller for filling an administration container |
US8740856B2 (en) | 2007-06-04 | 2014-06-03 | Becton, Dickinson And Company | Stoppers used in pre-filled syringes |
US9610404B2 (en) | 2011-09-07 | 2017-04-04 | Bigfoot Biomedical, Inc. | Method for occlusion detection for an infusion pump system |
US9629901B2 (en) | 2014-07-01 | 2017-04-25 | Bigfoot Biomedical, Inc. | Glucagon administration system and methods |
US9717849B2 (en) | 2007-05-21 | 2017-08-01 | Bigfoot Biomedical, Inc. | Occlusion sensing for an infusion pump |
US9757512B2 (en) | 2002-11-05 | 2017-09-12 | Bigfoot Biomedical, Inc. | Wearable insulin dispensing device, and a combination of such a device and a programming controller |
US9814830B2 (en) | 2005-09-26 | 2017-11-14 | Bigfoot Biomedical, Inc. | Dispensing fluid from an infusion pump system |
US9827376B2 (en) | 2014-01-29 | 2017-11-28 | Becton, Dickinson And Company | Plunger assembly including a plunger rod for advancing a stopper through a syringe |
US9872957B2 (en) | 2005-09-26 | 2018-01-23 | Bigfoot Biomedical, Inc. | Operating an infusion pump system |
US9878097B2 (en) | 2015-04-29 | 2018-01-30 | Bigfoot Biomedical, Inc. | Operating an infusion pump system |
US9919096B2 (en) | 2014-08-26 | 2018-03-20 | Bigfoot Biomedical, Inc. | Infusion pump system and method |
US9956339B2 (en) | 2013-06-03 | 2018-05-01 | Bigfoot Biomedical, Inc. | Infusion pump system and method |
US9962482B2 (en) | 2007-05-21 | 2018-05-08 | Bigfoot Biomedical, Inc. | Removable controller for an infusion pump |
US10064993B2 (en) | 2005-09-26 | 2018-09-04 | Bigfoot Biomedical, Inc. | Dispensing fluid from an infusion pump system |
US10105483B2 (en) | 2005-04-06 | 2018-10-23 | Bigfoot Biomedical, Inc. | Medicine dispensing device |
US10117993B2 (en) | 2007-09-07 | 2018-11-06 | Bigfoot Biomedical, Inc. | Activity sensing techniques for an infusion pump system |
US10137246B2 (en) | 2014-08-06 | 2018-11-27 | Bigfoot Biomedical, Inc. | Infusion pump assembly and method |
USD836769S1 (en) | 2016-12-12 | 2018-12-25 | Bigfoot Biomedical, Inc. | Insulin delivery controller |
USD839294S1 (en) | 2017-06-16 | 2019-01-29 | Bigfoot Biomedical, Inc. | Display screen with graphical user interface for closed-loop medication delivery |
US10207047B2 (en) | 2013-07-19 | 2019-02-19 | Bigfoot Biomedical, Inc. | Infusion pump system and method |
US10226575B2 (en) | 2007-09-07 | 2019-03-12 | Bigfoot Biomedical, Inc. | Power management techniques for an infusion pump system |
US10226572B2 (en) | 2007-09-06 | 2019-03-12 | Bigfoot Biomedical, Inc. | Operating a portable medical device |
US10232108B2 (en) | 2012-12-10 | 2019-03-19 | Bigfoot Biomedical, Inc. | Infusion pump system and method |
US10426896B2 (en) | 2016-09-27 | 2019-10-01 | Bigfoot Biomedical, Inc. | Medicine injection and disease management systems, devices, and methods |
US10449294B1 (en) | 2016-01-05 | 2019-10-22 | Bigfoot Biomedical, Inc. | Operating an infusion pump system |
US10569015B2 (en) | 2013-12-02 | 2020-02-25 | Bigfoot Biomedical, Inc. | Infusion pump system and method |
US10661007B2 (en) | 2013-03-01 | 2020-05-26 | Bigfoot Biomedical, Inc. | Operating an infusion pump system |
US10716895B2 (en) | 2013-06-03 | 2020-07-21 | Bigfoot Biomedical, Inc. | Infusion pump system and method |
US10987468B2 (en) | 2016-01-05 | 2021-04-27 | Bigfoot Biomedical, Inc. | Operating multi-modal medicine delivery systems |
US11096624B2 (en) | 2016-12-12 | 2021-08-24 | Bigfoot Biomedical, Inc. | Alarms and alerts for medication delivery devices and systems |
US11260169B2 (en) | 2013-03-14 | 2022-03-01 | Bigfoot Biomedical, Inc. | Infusion pump system and methods |
US11389088B2 (en) | 2017-07-13 | 2022-07-19 | Bigfoot Biomedical, Inc. | Multi-scale display of blood glucose information |
US11865299B2 (en) | 2008-08-20 | 2024-01-09 | Insulet Corporation | Infusion pump systems and methods |
Families Citing this family (22)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US20120209197A1 (en) * | 2002-01-04 | 2012-08-16 | Lanigan Richard J | Infusion pump assembly |
US20030120219A1 (en) * | 2001-12-06 | 2003-06-26 | Nielsen Lars Korsbjerg | Medical delivery system |
WO2004041330A2 (en) | 2002-11-05 | 2004-05-21 | M 2 Medical A/S | A disposable wearable insulin dispensing device, a combination of such a device and a programming controller and a method of controlling the operation of such a device |
US7666169B2 (en) * | 2003-11-25 | 2010-02-23 | Medrad, Inc. | Syringe and syringe plungers for use with medical injectors |
DE102004059126B4 (de) * | 2004-12-08 | 2014-01-16 | Roche Diagnostics Gmbh | Adapter für Injektionsgerät |
US8551046B2 (en) | 2006-09-18 | 2013-10-08 | Asante Solutions, Inc. | Dispensing fluid from an infusion pump system |
WO2007038060A2 (en) | 2005-09-26 | 2007-04-05 | M2 Medical A/S | Modular infusion pump having two different energy sources |
US8192394B2 (en) | 2005-11-08 | 2012-06-05 | Asante Solutions, Inc. | Method and system for manual and autonomous control of an infusion pump |
ITTO20060816A1 (it) * | 2006-11-16 | 2008-05-17 | Cane Srl | Stantuffo per siringa e siringa che incorpora lo stantuffo |
GB0700334D0 (en) * | 2007-01-09 | 2007-02-14 | Imi Vision Ltd | Pump |
US7833196B2 (en) | 2007-05-21 | 2010-11-16 | Asante Solutions, Inc. | Illumination instrument for an infusion pump |
US7794426B2 (en) | 2007-05-21 | 2010-09-14 | Asante Solutions, Inc. | Infusion pump system with contamination-resistant features |
US7935105B2 (en) | 2007-09-07 | 2011-05-03 | Asante Solutions, Inc. | Data storage for an infusion pump system |
US8961020B2 (en) | 2009-07-15 | 2015-02-24 | Sanofi-Aventis Deutschland Gmbh | Thrust bearing assembly, drive train, and medicament delivery device |
USD669165S1 (en) | 2010-05-27 | 2012-10-16 | Asante Solutions, Inc. | Infusion pump |
US8852152B2 (en) | 2011-02-09 | 2014-10-07 | Asante Solutions, Inc. | Infusion pump systems and methods |
CN103608056A (zh) * | 2011-04-20 | 2014-02-26 | 诺沃—诺迪斯克保健股份有限公司 | 活塞杆锚定 |
US8454557B1 (en) | 2012-07-19 | 2013-06-04 | Asante Solutions, Inc. | Infusion pump system and method |
US8454562B1 (en) | 2012-07-20 | 2013-06-04 | Asante Solutions, Inc. | Infusion pump system and method |
USD809134S1 (en) | 2016-03-10 | 2018-01-30 | Bigfoot Biomedical, Inc. | Infusion pump assembly |
DE102022116513B3 (de) | 2022-07-01 | 2023-08-10 | Lenus Infusionstechnik Gmbh & Co. Kg | Dosiersystem |
EP4309706A1 (de) * | 2022-07-21 | 2024-01-24 | Becton Dickinson France | Universelle kolbenstange und verfahren zum verbinden und trennen der kolbenstange und eines kolbenstoppers |
Citations (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE2715969A1 (de) | 1976-06-01 | 1978-02-02 | Wimmer Pharma Gummi Gmbh | Injektionsspritzen-satz, insbesondere mit kolbenstange und kolben fuer eine injektionsspritze |
Family Cites Families (23)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CA651985A (en) * | 1962-11-13 | P. Maxwell William | Fastening device | |
US2473733A (en) * | 1947-05-31 | 1949-06-21 | Arthur E Smith | Syringe |
US2509192A (en) * | 1947-06-19 | 1950-05-23 | Illinois Tool Works | Drive fastener |
US3115804A (en) * | 1959-11-16 | 1963-12-31 | Wisconsin Alumni Res Found | Snap bolt having resiliently flexible shank portion |
US3466966A (en) * | 1967-11-13 | 1969-09-16 | Robin Products Co | Resilient fastening device in threaded bore |
AT285909B (de) * | 1968-10-07 | 1970-11-25 | Langensiepen Kg M | Befestigungselement |
DE7024161U (de) * | 1970-06-26 | 1972-10-05 | Fa B Braun | Injektionsspritze |
CH603170A5 (de) * | 1976-08-31 | 1978-08-15 | Contraves Ag | |
IT1145830B (it) * | 1980-02-12 | 1986-11-12 | Franz Astl | Dispositivo per la giunzione scioglibile di due elementi |
US4728238A (en) * | 1980-06-16 | 1988-03-01 | Illinois Tool Works Inc. | Plastic drive fastener |
EP0346950B2 (de) * | 1984-06-06 | 1997-09-10 | Medrad Incorporated | Angiographie-Spritze für Verwendung mit einem Angiographie-Injektor |
DE3573822D1 (en) * | 1985-05-08 | 1989-11-23 | Franz Astl | Device for the connection of two elements |
DE3907096A1 (de) * | 1989-02-27 | 1990-08-30 | Holzer Walter | Verfahren und ausfuehrung einer injektionsspritze zum einmaligen gebrauch |
US4911695A (en) * | 1989-04-03 | 1990-03-27 | Coeur Laboratories, Inc. | Plunger for power-driven angiographic syringe, and syringe and power injector system utilizing same |
US5084017A (en) * | 1989-10-10 | 1992-01-28 | John Maffetone | Self disabling, single use, hypodermic syringe |
US5873861A (en) * | 1996-11-12 | 1999-02-23 | Medrad, Inc. | Plunger systems |
DE19925621A1 (de) * | 1998-06-16 | 1999-12-23 | Buelent Yilmaz | Injektionsspritze |
US6817990B2 (en) * | 1998-10-29 | 2004-11-16 | Medtronic Minimed, Inc. | Fluid reservoir piston |
US6196999B1 (en) * | 1999-02-05 | 2001-03-06 | Liebel-Flarsheim Company | Syringe/plunger coupling |
US8465468B1 (en) * | 2000-06-29 | 2013-06-18 | Becton, Dickinson And Company | Intradermal delivery of substances |
NL1014082C2 (nl) * | 2000-01-17 | 2001-07-18 | Franciscus Antonius Maria Van | Systeem voor het verbinden van elementen. |
US6485465B2 (en) * | 2000-03-29 | 2002-11-26 | Medtronic Minimed, Inc. | Methods, apparatuses, and uses for infusion pump fluid pressure and force detection |
US20020072720A1 (en) * | 2000-12-11 | 2002-06-13 | Hague Clifford W. | Rigid soluble materials for use with needle-less infusion sets, sensor sets and injection devices and methods of making the same |
-
2003
- 2003-07-03 DE DE10330094A patent/DE10330094B4/de not_active Expired - Fee Related
-
2004
- 2004-06-24 CA CA002525797A patent/CA2525797A1/en not_active Abandoned
- 2004-06-24 WO PCT/EP2004/006846 patent/WO2005002652A2/de active Application Filing
- 2004-06-24 EP EP04740259A patent/EP1642094A2/de not_active Withdrawn
- 2004-06-24 JP JP2006518033A patent/JP2009513167A/ja active Pending
-
2005
- 2005-12-21 US US11/314,814 patent/US7798377B2/en not_active Expired - Fee Related
Patent Citations (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE2715969A1 (de) | 1976-06-01 | 1978-02-02 | Wimmer Pharma Gummi Gmbh | Injektionsspritzen-satz, insbesondere mit kolbenstange und kolben fuer eine injektionsspritze |
Cited By (74)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US9757512B2 (en) | 2002-11-05 | 2017-09-12 | Bigfoot Biomedical, Inc. | Wearable insulin dispensing device, and a combination of such a device and a programming controller |
US10105483B2 (en) | 2005-04-06 | 2018-10-23 | Bigfoot Biomedical, Inc. | Medicine dispensing device |
US10603431B2 (en) | 2005-09-26 | 2020-03-31 | Bigfoot Biomedical, Inc. | Dispensing fluid from an infusion pump system |
US9872957B2 (en) | 2005-09-26 | 2018-01-23 | Bigfoot Biomedical, Inc. | Operating an infusion pump system |
US10064993B2 (en) | 2005-09-26 | 2018-09-04 | Bigfoot Biomedical, Inc. | Dispensing fluid from an infusion pump system |
US9814830B2 (en) | 2005-09-26 | 2017-11-14 | Bigfoot Biomedical, Inc. | Dispensing fluid from an infusion pump system |
US10307536B2 (en) | 2005-09-26 | 2019-06-04 | Bigfoot Biomedical, Inc. | Operating an infusion pump system |
US8551045B2 (en) | 2006-04-19 | 2013-10-08 | Novo Nordisk A/S | Fluid infusion system, a method of assembling such system and drug reservoir for use in the system |
JP2009534073A (ja) * | 2006-04-19 | 2009-09-24 | ノボ・ノルデイスク・エー/エス | 流体注入システム、同システムの組み立て方法及び同システムで使用される薬剤容器 |
WO2007118907A1 (en) | 2006-04-19 | 2007-10-25 | Novo Nordisk A/S | A fluid infusion system, a method of assembling such system and drug reservoir for use in the system |
US8118781B2 (en) | 2006-04-19 | 2012-02-21 | Novo Nordisk A/S | Fluid infusion system, a method of assembling such system and drug reservoir for use in the system |
WO2008103175A1 (en) * | 2007-02-22 | 2008-08-28 | M2 Group Holdings, Inc. | Portable infusion pump with flexible piston rod |
US9717849B2 (en) | 2007-05-21 | 2017-08-01 | Bigfoot Biomedical, Inc. | Occlusion sensing for an infusion pump |
US9962482B2 (en) | 2007-05-21 | 2018-05-08 | Bigfoot Biomedical, Inc. | Removable controller for an infusion pump |
WO2008151241A3 (en) * | 2007-06-04 | 2009-01-29 | Becton Dickinson Co | Stopper and plunger rod for a pre-filled syringe |
EP2167172B1 (de) * | 2007-06-04 | 2019-03-06 | Becton, Dickinson and Company | Stopfen und kolbenstange für eine fertigspritze |
US9592346B2 (en) | 2007-06-04 | 2017-03-14 | Becton, Dickinson And Company | Stoppers used in pre-filled syringes |
US10183118B2 (en) | 2007-06-04 | 2019-01-22 | Becton, Dickinson And Company | Stoppers used in pre-filled syringes |
US8740856B2 (en) | 2007-06-04 | 2014-06-03 | Becton, Dickinson And Company | Stoppers used in pre-filled syringes |
US8740854B2 (en) | 2007-06-04 | 2014-06-03 | Becton, Dickinson And Company | Stopper and plunger rod for a pre-filled syringe |
WO2008151241A2 (en) | 2007-06-04 | 2008-12-11 | Becton, Dickinson And Company | Stopper and plunger rod for a pre-filled syringe |
US9649444B2 (en) | 2007-06-04 | 2017-05-16 | Becton, Dickinson And Company | Positive displacement stopper for a pre-filled syringe |
US8475415B2 (en) | 2007-06-04 | 2013-07-02 | Becton, Dickinson And Company | Positive displacement stopper for a pre-filled syringe |
EP3505207A3 (de) * | 2007-06-04 | 2019-09-25 | Becton, Dickinson and Company | Stopfen und kolbenstange für eine vorgefüllte spritze |
US10226572B2 (en) | 2007-09-06 | 2019-03-12 | Bigfoot Biomedical, Inc. | Operating a portable medical device |
US11000645B2 (en) | 2007-09-06 | 2021-05-11 | Bigfoot Biomedical, Inc. | Operating a portable medical device |
US10632257B2 (en) | 2007-09-07 | 2020-04-28 | Bigfoot Biomedical, Inc. | Activity sensing techniques for an infusion pump system |
US10117993B2 (en) | 2007-09-07 | 2018-11-06 | Bigfoot Biomedical, Inc. | Activity sensing techniques for an infusion pump system |
US10226575B2 (en) | 2007-09-07 | 2019-03-12 | Bigfoot Biomedical, Inc. | Power management techniques for an infusion pump system |
US11241534B2 (en) | 2007-09-07 | 2022-02-08 | Bigfoot Biomedical, Inc. | Power management techniques for an infusion pump system |
US11865299B2 (en) | 2008-08-20 | 2024-01-09 | Insulet Corporation | Infusion pump systems and methods |
US9610407B2 (en) | 2009-02-05 | 2017-04-04 | Sanofi-Aventis Deutschland Gmbh | Medicament delivery devices |
US9107996B2 (en) | 2009-02-05 | 2015-08-18 | Sanofi-Aventis Deutschland Gmbh | Medicament delivery devices |
CN102307605A (zh) * | 2009-02-05 | 2012-01-04 | 赛诺菲-安万特德国有限公司 | 药物递送装置 |
AU2010210160B2 (en) * | 2009-02-05 | 2014-09-04 | Sanofi-Aventis Deutschland Gmbh | Medicament delivery devices |
WO2010089310A1 (en) * | 2009-02-05 | 2010-08-12 | Sanofi-Aventis Deutschland Gmbh | Medicament delivery devices |
WO2012139878A1 (en) * | 2011-04-15 | 2012-10-18 | F. Hoffmann-La Roche Ag | Device for moving a piston inside a cartridge |
EP2510963A1 (de) * | 2011-04-15 | 2012-10-17 | F.Hoffmann-La Roche Ag | Vorrichtung zum Bewegen eines Kolbens in einer Kartusche |
US9610400B2 (en) | 2011-04-15 | 2017-04-04 | Roche Diagnostics International Ag | Device for moving a piston inside a cartridge |
US9610404B2 (en) | 2011-09-07 | 2017-04-04 | Bigfoot Biomedical, Inc. | Method for occlusion detection for an infusion pump system |
WO2013135275A1 (en) | 2012-03-13 | 2013-09-19 | F. Hoffmann-La Roche Ag | Filling device and controller for filling an administration container |
US9611058B2 (en) | 2012-03-13 | 2017-04-04 | Roche Diabetes Care, Inc. | Filling device and controller for filling an administration container |
US10232108B2 (en) | 2012-12-10 | 2019-03-19 | Bigfoot Biomedical, Inc. | Infusion pump system and method |
US11191891B2 (en) | 2012-12-10 | 2021-12-07 | Bigfoot Biomedical, Inc. | Infusion pump system and method |
US10661007B2 (en) | 2013-03-01 | 2020-05-26 | Bigfoot Biomedical, Inc. | Operating an infusion pump system |
US11260169B2 (en) | 2013-03-14 | 2022-03-01 | Bigfoot Biomedical, Inc. | Infusion pump system and methods |
US10716895B2 (en) | 2013-06-03 | 2020-07-21 | Bigfoot Biomedical, Inc. | Infusion pump system and method |
US9956339B2 (en) | 2013-06-03 | 2018-05-01 | Bigfoot Biomedical, Inc. | Infusion pump system and method |
US11147914B2 (en) | 2013-07-19 | 2021-10-19 | Bigfoot Biomedical, Inc. | Infusion pump system and method |
US10207047B2 (en) | 2013-07-19 | 2019-02-19 | Bigfoot Biomedical, Inc. | Infusion pump system and method |
US10569015B2 (en) | 2013-12-02 | 2020-02-25 | Bigfoot Biomedical, Inc. | Infusion pump system and method |
US11464906B2 (en) | 2013-12-02 | 2022-10-11 | Bigfoot Biomedical, Inc. | Infusion pump system and method |
US9827376B2 (en) | 2014-01-29 | 2017-11-28 | Becton, Dickinson And Company | Plunger assembly including a plunger rod for advancing a stopper through a syringe |
US10549037B2 (en) | 2014-07-01 | 2020-02-04 | Bigfoot Biomedical, Inc. | Glucagon administration system and methods |
US9629901B2 (en) | 2014-07-01 | 2017-04-25 | Bigfoot Biomedical, Inc. | Glucagon administration system and methods |
US10994078B2 (en) | 2014-08-06 | 2021-05-04 | Bigfoot Biomedical, Inc. | Infusion pump assembly and method |
US10137246B2 (en) | 2014-08-06 | 2018-11-27 | Bigfoot Biomedical, Inc. | Infusion pump assembly and method |
EP3185929A4 (de) * | 2014-08-26 | 2018-04-11 | Bigfoot Biomedical, Inc. | Infusionspumpensystem und -verfahren |
US10661008B2 (en) | 2014-08-26 | 2020-05-26 | Bigfoot Biomedical, Inc. | Infusion pump system and method |
US9919096B2 (en) | 2014-08-26 | 2018-03-20 | Bigfoot Biomedical, Inc. | Infusion pump system and method |
US9878097B2 (en) | 2015-04-29 | 2018-01-30 | Bigfoot Biomedical, Inc. | Operating an infusion pump system |
US10603433B2 (en) | 2015-04-29 | 2020-03-31 | Bigfoot Biomedical, Inc. | Operating an infusion pump system |
US11471598B2 (en) | 2015-04-29 | 2022-10-18 | Bigfoot Biomedical, Inc. | Operating an infusion pump system |
US10987468B2 (en) | 2016-01-05 | 2021-04-27 | Bigfoot Biomedical, Inc. | Operating multi-modal medicine delivery systems |
US10449294B1 (en) | 2016-01-05 | 2019-10-22 | Bigfoot Biomedical, Inc. | Operating an infusion pump system |
US10426896B2 (en) | 2016-09-27 | 2019-10-01 | Bigfoot Biomedical, Inc. | Medicine injection and disease management systems, devices, and methods |
US11229751B2 (en) | 2016-09-27 | 2022-01-25 | Bigfoot Biomedical, Inc. | Personalizing preset meal sizes in insulin delivery system |
US11806514B2 (en) | 2016-09-27 | 2023-11-07 | Bigfoot Biomedical, Inc. | Medicine injection and disease management systems, devices, and methods |
US11957888B2 (en) | 2016-09-27 | 2024-04-16 | Bigfoot Biomedical, Inc. | Personalizing preset meal sizes in insulin delivery system |
US11096624B2 (en) | 2016-12-12 | 2021-08-24 | Bigfoot Biomedical, Inc. | Alarms and alerts for medication delivery devices and systems |
USD836769S1 (en) | 2016-12-12 | 2018-12-25 | Bigfoot Biomedical, Inc. | Insulin delivery controller |
USD852837S1 (en) | 2017-06-16 | 2019-07-02 | Bigfoot Biomedical, Inc. | Display screen with graphical user interface for closed-loop medication delivery |
USD839294S1 (en) | 2017-06-16 | 2019-01-29 | Bigfoot Biomedical, Inc. | Display screen with graphical user interface for closed-loop medication delivery |
US11389088B2 (en) | 2017-07-13 | 2022-07-19 | Bigfoot Biomedical, Inc. | Multi-scale display of blood glucose information |
Also Published As
Publication number | Publication date |
---|---|
DE10330094B4 (de) | 2008-04-17 |
US7798377B2 (en) | 2010-09-21 |
US20060151545A1 (en) | 2006-07-13 |
WO2005002652A3 (de) | 2005-08-18 |
CA2525797A1 (en) | 2005-01-13 |
DE10330094A1 (de) | 2005-02-24 |
EP1642094A2 (de) | 2006-04-05 |
JP2009513167A (ja) | 2009-04-02 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
DE10330094B4 (de) | Vorrichtung zur Verabreichung eines flüssigen Produkts | |
EP2077878B1 (de) | Injektionsgerät mit verbessertem förderelement | |
EP1988952B1 (de) | Injektionsvorrichtung mit gesichertem dosierknopf | |
WO2003011374A1 (de) | Verabreichungsgerät mit verdrehsicherung | |
WO2003011372A2 (de) | Reservoirmodul mit kolbenstange | |
WO2003011370A2 (de) | Verriegelungssperre für eine verbindung von gehäuseabschnitten eines verabreichungsgeräts | |
WO2004002557A1 (de) | Verabreichungsgerät mit rücksetzbarer betätigungssperre | |
WO2003011371A2 (de) | Verabreichungsgerät mit dosiervorrichtung | |
WO2005072796A2 (de) | Injektionsgerät mit verrastbarem dosierglied | |
DE102006004563A1 (de) | Ausfahrbarer Dosierknopf | |
WO2005102420A1 (de) | Vorrichtung zur verabreichung eines injizierbaren produkts mit gesicherter dosiereinrichtung | |
EP1981570B1 (de) | Vorschubstange mit koppelelement | |
DE20112501U1 (de) | Verriegelungssperre für eine Verbindung von Gehäuseteilen eines Injektions- oder Infusionsgeräts | |
WO2004006997A1 (de) | Verabreichungsgerät mit rückzugsgesperrter kolbenstange |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
AK | Designated states |
Kind code of ref document: A2 Designated state(s): AE AG AL AM AT AU AZ BA BB BG BR BW BY BZ CA CH CN CO CR CU CZ DE DK DM DZ EC EE EG ES FI GB GD GE GH GM HR HU ID IL IN IS JP KE KG KP KR KZ LC LK LR LS LT LU LV MA MD MG MK MN MW MX MZ NA NI NO NZ OM PG PH PL PT RO RU SC SD SE SG SK SL SY TJ TM TN TR TT TZ UA UG US UZ VC VN YU ZA ZM ZW |
|
AL | Designated countries for regional patents |
Kind code of ref document: A2 Designated state(s): GM KE LS MW MZ NA SD SL SZ TZ UG ZM ZW AM AZ BY KG KZ MD RU TJ TM AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IT LU MC NL PL PT RO SE SI SK TR BF BJ CF CG CI CM GA GN GQ GW ML MR NE SN TD TG |
|
121 | Ep: the epo has been informed by wipo that ep was designated in this application | ||
WWE | Wipo information: entry into national phase |
Ref document number: 2004740259 Country of ref document: EP |
|
WWE | Wipo information: entry into national phase |
Ref document number: 2525797 Country of ref document: CA |
|
WWE | Wipo information: entry into national phase |
Ref document number: 11314814 Country of ref document: US |
|
WWE | Wipo information: entry into national phase |
Ref document number: 2006518033 Country of ref document: JP |
|
WWP | Wipo information: published in national office |
Ref document number: 2004740259 Country of ref document: EP |
|
WWP | Wipo information: published in national office |
Ref document number: 11314814 Country of ref document: US |