WO2004112946B1 - Reactor with memory component - Google Patents

Reactor with memory component

Info

Publication number
WO2004112946B1
WO2004112946B1 PCT/US2004/018637 US2004018637W WO2004112946B1 WO 2004112946 B1 WO2004112946 B1 WO 2004112946B1 US 2004018637 W US2004018637 W US 2004018637W WO 2004112946 B1 WO2004112946 B1 WO 2004112946B1
Authority
WO
WIPO (PCT)
Prior art keywords
data
data storage
storage component
chip
reaction site
Prior art date
Application number
PCT/US2004/018637
Other languages
French (fr)
Other versions
WO2004112946A3 (en
WO2004112946A2 (en
Filing date
Publication date
Application filed filed Critical
Priority to EP04755035A priority Critical patent/EP1628748A2/en
Publication of WO2004112946A2 publication Critical patent/WO2004112946A2/en
Publication of WO2004112946A3 publication Critical patent/WO2004112946A3/en
Publication of WO2004112946B1 publication Critical patent/WO2004112946B1/en

Links

Abstract

The present invention provides techniques for conveniently and reliably storing and/or retrieving data associated with a chemical, biological, or biochemical chip, reactor, or reaction system. The data can pertain to the reactor; to chemical, biological, or biochemical species introduced into, taken from, or otherwise associated with the reactor; to conditions to which the reactor and/or some or all of its contents has been, is being, or will be exposed to, or the like. Various aspects of the present invention relate to memory and data storage components suitable for use in chips or other reaction systems. These components may include silicon integrated circuits, magnetic media, optical media, radio-frequency tags, smart cards, bar-codes and other kinds of data storage devices. The chip may contain a reaction site having a volume of less than about 2 ml. In some embodiments, the chip may be constructed in such a way as to be able to support a living cell. The chip may be used for imaging or analysis, or the chip may be used to facilitate a chemical or biological reaction, which may be light-sensitive or light activated in certain cases. Other facilitated reactions may include the production and/or consumption of a chemical or biological species. In some embodiments, the chip may include more than one component or component type, and/or more than one reaction site.

Claims

35AMENDED CLAIMS[Received by the International Bureau on 15 February 2005 (15.02.2005); original claims 1-67 replaced by amended claims 1-67 (7 pages)]
1. An apparatus, comprising: a chemical, biological, or biochemical reactor chip comprising a predetermined reaction site having a volume of less than about 2 ml, the chip constructed and arranged to maintain at least one living cell at the predetermined reaction site; and at least one data storage component associated with the chip.
2. (Canceled)
3. The apparatus of claim 1, comprising a plurality of reaction sites.
4. The apparatus of claim 1, wherein the predetermined reaction site has a volume of less than about 500 microliters.
5. The apparatus of claim 1, wherein the predetermined reaction site has a volume of less than about 100 microliters.
6. The apparatus of claim 1, wherein the predetermined reaction site has a volume of less than about 10 microliters.
7. The apparatus of claim 1, wherein the predetermined reaction site has a volume of less than about 1 microliter.
8. The apparatus of claim 1, wherein the predetermined reaction site has a maximum dimension of less than about 1 cm.
9. The apparatus of claim 1, wherein the predetermined reaction site has a maximum dimension of less than about 1 mm.
10. The apparatus of claim 1, wherein the predetermined reaction site has a maximum dimension of less than about 100 micrometers. 36
11. The apparatus of claim 1, wherein the predetermined reaction site has a maximum dimension of less than about 10 micrometers.
12. The apparatus of claim 1, wherein the at least one data storage component comprises a computer-readable medium.
13. The apparatus of claim 1, wherein the at least one data storage component is non-volatile.
14. The apparatus of claim 1, wherein the at least one data storage component is volatile.
15. The apparatus of claim 1, wherein the at least one data storage component comprises a magnetic medium.
16. The apparatus of claim 15, wherein the magnetic medium comprises a magnetic strip.
17. The apparatus of claim 1, wherein the at least one data storage component comprises an optical medium.
18. The apparatus of claim 1, wherein the optical medium is laser-readable.
19. The apparatus of claim 1, wherein the at least one data storage component comprises a semiconductor chip.
20. The apparatus of claim 1, wherein the at least one data storage component comprises a silicon chip.
21. The apparatus of claim 1, wherein the at least one data storage component comprises a radio frequency tag.
22. The apparatus of claim 1, wherein the at least one data storage component comprises a bar code.
23. The apparatus of claim 1, wherein the at least one data storage component is reversibly attachable.
24. The apparatus of claim 1, wherein the at least one data storage component is rotatable.
25. The apparatus of claim 1, wherein the at least one data storage component is rewritable.
26. The apparatus of claim 1, wherein the at least one data storage component is read-only.
27. The apparatus of claim 1, wherein the predetermined reaction site comprises at least one substantially hydrophobic surface.
28. The apparatus of claim 1, wherein the predetermined reaction site comprises at least one substantially hydrophilic surface.
29. The apparatus of claim 1, wherein the predetermined reaction site comprises at least one substantially cytophobic surface.
30. The apparatus of claim 1, wherein the predetermined reaction site comprises at least one substantially cytophilic surface.
31. The apparatus of claim 1 , wherein the at least one data component is able to store data associated with the reaction site.
32. The apparatus of claim 1, wherein the at least one data storage component comprises a compact disc or a digital versatile disc. 38
33. The apparatus of claim 1, wherein the at least one data storage component comprises flash memory.
34. The apparatus of claim 1, wherein the at least one data storage component comprises an integrated circuit.
35. The apparatus of claim 1, wherein the at least one data storage component is a memory stick.
36. The apparatus of claim 1, wherein the at least one data storage component is reversibly removable from the chip.
37. The apparatus of claim 1, wherein the at least one data storage component can be exposed to gamma rays without deformation.
38. The apparatus of claim 1, wherein the at least one data storage component can be exposed to ultraviolet radiation without deformation.
39. The apparatus of claim 1, wherein the at least one data storage component can be heated to a temperature of at least about 370C without deformation.
40. The apparatus of claim 39, wherein the at least one data storage component can be heated to a temperature of at least about 100 0C without deformation.
41. The apparatus of claim 1, wherein the at least one data storage component is moisture-resistant.
42. A system, comprising the apparatus of claim 1, and an external data interface able to interface with the at least one data storage compartment.
43. A method, comprising: transferring data to or from a chemical, biological, or biochemical reactor chip comprising a data storage component and a predetermined reaction 39
site having a volume of less than about 2 ml, wherein the chip is constructed and arranged to maintain at least one living cell at the predetermined reaction site.
44. The method of claim 43, wherein the data is associated with the reaction site.
45. The method of claim 44, wherein the data identifies the chip.
46. The method of claim 44, wherein the data comprises a measurement of an environmental condition of the reaction site.
47. The method of claim 43, wherein the data is transferred to an external data interface.
48. The method of claim 47, wherein the data is transferred to the external data interface through an electrical connection.
49. The method of claim 47, wherein the data is transferred to the external data interface through a wireless connection.
50. The method of claim 49, wherein the wireless connection is a Bluetooth transmission protocol.
51. The method of claim 47, wherein the data is transferred to the external data interface using a radio wave.
52. The method of claim 47, wherein the data is transferred to the external data interface using a light interaction.
53. The method of claim 47, wherein the data is transferred to the external data interface using a magnetic interaction. 40
54. A system, comprising: a chemical, biological, or biochemical reactor chip comprising a predetermined reaction site and a data storage component, wherein the chip is constructed and arranged to maintain at least one living cell at the predetermined reaction site; and an external data interface able to interface with the data storage component.
55. The system of claim 54, wherein the external data interface is able to write data to the data storage component.
56. The system of claim 54, wherein the external data interface is able to read data from the data storage component.
57. A system, comprising: a holder able to secure a chemical, biological, or biochemical reactor chip; and an external data interface positioned to interface with a chip secured by the holder.
58. The system of claim 57, wherein the external data interface is positioned to magnetically interface with the chip.
59. The system of claim 57, wherein the external data interface is positioned to establish an electrical connection with the chip.
60. The system of claim 57, wherein the external data interface is positioned to interface with the chip through a wireless connection.
61. The system of claim 60, wherein the external data interface is positioned to interface with the chip through a radio wave. 41
62. The system of claim 60, wherein the external data interface is positioned to interface with the chip through a light interaction.
63. The system of claim 60, wherein the external data interface is positioned to interface with the chip through a laser interaction.
64. A method, comprising: storing data to and/or retrieving data from a data storage component of a chemical, biological, or biochemical reactor chip comprising a predetermined reaction site having a volume of less than about 2 ml, wherein the chip is constructed and arranged to maintain at least one living cell at the predetermined reaction site.
65. A method as in claim 64, comprising storing data to the data storage component.
66. A method as in claim 64, comprising retrieving data from the data storage component.
61. A method as in claim 64, comprising storing data to and retrieving data from the data storage component.
PCT/US2004/018637 2003-06-05 2004-06-07 Reactor with memory component WO2004112946A2 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
EP04755035A EP1628748A2 (en) 2003-06-05 2004-06-07 Reactor with memory component

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US45701703A 2003-06-05 2003-06-05
US10/457,017 2003-06-05
US49912403P 2003-08-29 2003-08-29
US60/499,124 2003-08-29

Publications (3)

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WO2004112946A2 WO2004112946A2 (en) 2004-12-29
WO2004112946A3 WO2004112946A3 (en) 2005-02-24
WO2004112946B1 true WO2004112946B1 (en) 2006-01-12

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US (1) US20050026273A1 (en)
EP (1) EP1628748A2 (en)
WO (1) WO2004112946A2 (en)

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