WO2004105738A3 - Utilisation de derives de tetrahydropyridine - Google Patents

Utilisation de derives de tetrahydropyridine Download PDF

Info

Publication number
WO2004105738A3
WO2004105738A3 PCT/EP2004/005064 EP2004005064W WO2004105738A3 WO 2004105738 A3 WO2004105738 A3 WO 2004105738A3 EP 2004005064 W EP2004005064 W EP 2004005064W WO 2004105738 A3 WO2004105738 A3 WO 2004105738A3
Authority
WO
WIPO (PCT)
Prior art keywords
tetrahydropyridine derivatives
compounds
preparation
pharmaceutical compositions
tetrahydropyridine
Prior art date
Application number
PCT/EP2004/005064
Other languages
English (en)
Other versions
WO2004105738A2 (fr
Inventor
Daniel Bur
Walter Fischli
Lubos Remen
Sylvia Richard-Bildstein
Thomas Weller
Christoph Boss
Christoph Binkert
Solange Meyer
Original Assignee
Actelion Pharmaceuticals Ltd
Daniel Bur
Walter Fischli
Lubos Remen
Sylvia Richard-Bildstein
Thomas Weller
Christoph Boss
Christoph Binkert
Solange Meyer
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Actelion Pharmaceuticals Ltd, Daniel Bur, Walter Fischli, Lubos Remen, Sylvia Richard-Bildstein, Thomas Weller, Christoph Boss, Christoph Binkert, Solange Meyer filed Critical Actelion Pharmaceuticals Ltd
Publication of WO2004105738A2 publication Critical patent/WO2004105738A2/fr
Publication of WO2004105738A3 publication Critical patent/WO2004105738A3/fr

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4418—Non condensed pyridines; Hydrogenated derivatives thereof having a carbocyclic group directly attached to the heterocyclic ring, e.g. cyproheptadine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A61P33/02—Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis
    • A61P33/06—Antimalarials
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

La présente invention concerne des dérivés de tétrahydropyridine et des composés associés, et leur utilisation comme ingrédients actifs dans la préparation de compositions pharmaceutiques. L'invention se rapporte également à des aspects connexes, par exemple à des procédés de préparation desdits composés et de compositions pharmaceutiques contenant un ou plusieurs des composés précités et, en particulier, à leur utilisation comme inhibiteurs de la plasmepsine II.
PCT/EP2004/005064 2003-05-30 2004-05-12 Utilisation de derives de tetrahydropyridine WO2004105738A2 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP0305662 2003-05-30
EPPCT/EP03/05662 2003-05-30

Publications (2)

Publication Number Publication Date
WO2004105738A2 WO2004105738A2 (fr) 2004-12-09
WO2004105738A3 true WO2004105738A3 (fr) 2005-03-03

Family

ID=33483763

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/EP2004/005064 WO2004105738A2 (fr) 2003-05-30 2004-05-12 Utilisation de derives de tetrahydropyridine

Country Status (1)

Country Link
WO (1) WO2004105738A2 (fr)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20090186874A1 (en) * 2004-01-14 2009-07-23 Yoshinori Ikeura Carboxamide derivative and use thereof

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2004002957A1 (fr) * 2002-06-27 2004-01-08 Actelion Pharmaceuticals Ltd Nouveaux derives de tetrahydropyridine en tant qu'inhibiteurs de renine

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2004002957A1 (fr) * 2002-06-27 2004-01-08 Actelion Pharmaceuticals Ltd Nouveaux derives de tetrahydropyridine en tant qu'inhibiteurs de renine

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
BOSS C ET AL: "INHIBITORS OF THE PLASMODIUM FALCIPARUM PARASITE ASPARTIC PROTEASE PLASMEPSIN II AS POTENTIAL ANTIMALARIAL AGENTS", CURRENT MEDICINAL CHEMISTRY, BENTHAM SCIENCE PUBLISHERS BV, BE, vol. 10, no. 11, 2003, pages 883 - 907, XP009036752, ISSN: 0929-8673 *

Also Published As

Publication number Publication date
WO2004105738A2 (fr) 2004-12-09

Similar Documents

Publication Publication Date Title
TW200514772A (en) Novel tetrahydropyridine derivatives
WO2004033418A3 (fr) Derives d'acide sulfonylamino-acetique
MY143795A (en) Tetrahydropyridoindole derivatives
BRPI0508579A (pt) composto, composição farmacêutica, e, uso de um composto
WO2004026836A3 (fr) Derives de 1-pyridin-4-yl-uree
MY144992A (en) Substituted 1,2,3,4-tetrahydroisoquinoline derivatives.
WO2005004818A3 (fr) Composes heterocycliques et leur utilisation comme agents anticancereux
AU2003244632A1 (en) Bicyclo-pyrazoles active as kinase inhibitors, process for their preparation and pharmaceutical compositions comprising them
TW200514786A (en) Novel diazabicyclononene derivatives
TW200621773A (en) Bicyclononene derivatives
AU2003244649A1 (en) Bicyclo-pyrazoles active as kinase inhibitors, process for their preparation and pharmaceutical compositions comprising them
NO20055623L (no) Azabicyklononenderivater
WO2007102127A3 (fr) Nouvelles amines
HUP0400832A3 (en) New amidoalkyl-piperidine and amidoalkyl-piperazine derivatives, and pharmaceutical compositions containing such derivatives as active ingredients
WO2006129237A3 (fr) Nouveaux derives d'amide d'acide piperidine carboxylique
WO2006021401A3 (fr) Derives de bicyclononene
CA2361402A1 (fr) Bis-sulfonamides
WO2005054244A3 (fr) Derives de diazabicyclononene et de tetrahydropyridine comprenant une nouvelle chaine laterale
WO2005030209A8 (fr) Derives de pyridine et leur utilisation comme antagonistes de l'urotensine ii
WO2004096116A3 (fr) Derives de diazabicyclononene
WO2004113297A3 (fr) Derives de noyaux aza et utilisation de ceux-ci comme inhibiteurs de la recapture des neurotransmetteurs monoaminergiques
WO2002070464A3 (fr) Nouvelles hydrazones
MXPA05011498A (es) Derivados de 9-azabiciclo[3.3.1]non-6-eno con un heteroatomo en la posicion 3 como inhibidores de renina.
MXPA05011497A (es) Derivados de tropano y su uso como inhibidores de la enzima de conversion de angiotensina (ace).
WO2007099509A3 (fr) NouveLLES aminEs primaires

Legal Events

Date Code Title Description
AK Designated states

Kind code of ref document: A2

Designated state(s): AE AG AL AM AT AU AZ BA BB BG BR BW BY BZ CA CH CN CO CR CU CZ DE DK DM DZ EC EE EG ES FI GB GD GE GH GM HR HU ID IL IN IS JP KE KG KP KR KZ LC LK LR LS LT LU LV MA MD MG MK MN MW MX MZ NA NI NO NZ OM PG PH PL PT RO RU SC SD SE SG SK SL SY TJ TM TN TR TT TZ UA UG US UZ VC VN YU ZA ZM ZW

AL Designated countries for regional patents

Kind code of ref document: A2

Designated state(s): GM KE LS MW MZ NA SD SL SZ TZ UG ZM ZW AM AZ BY KG KZ MD RU TJ TM AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IT LU MC NL PL PT RO SE SI SK TR BF BJ CF CG CI CM GA GN GQ GW ML MR NE SN TD TG

121 Ep: the epo has been informed by wipo that ep was designated in this application
122 Ep: pct application non-entry in european phase