WO2004085683A3 - Method for early carcinoma detection and a test kit for carrying our said method - Google Patents

Method for early carcinoma detection and a test kit for carrying our said method Download PDF

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Publication number
WO2004085683A3
WO2004085683A3 PCT/EP2004/003044 EP2004003044W WO2004085683A3 WO 2004085683 A3 WO2004085683 A3 WO 2004085683A3 EP 2004003044 W EP2004003044 W EP 2004003044W WO 2004085683 A3 WO2004085683 A3 WO 2004085683A3
Authority
WO
WIPO (PCT)
Prior art keywords
carrying
test kit
early carcinoma
carcinoma detection
papilloma virus
Prior art date
Application number
PCT/EP2004/003044
Other languages
German (de)
French (fr)
Other versions
WO2004085683A2 (en
Inventor
Ralf Hilfrich
Original Assignee
Buchner Erwin
Ralf Hilfrich
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Buchner Erwin, Ralf Hilfrich filed Critical Buchner Erwin
Priority to EP04722574A priority Critical patent/EP1656561A2/en
Priority to JP2006504811A priority patent/JP2006521104A/en
Publication of WO2004085683A2 publication Critical patent/WO2004085683A2/en
Publication of WO2004085683A3 publication Critical patent/WO2004085683A3/en

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/70—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving virus or bacteriophage
    • C12Q1/701—Specific hybridization probes
    • C12Q1/708—Specific hybridization probes for papilloma
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
    • C12Q1/6886—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material for cancer

Abstract

The invention relates to a method for early carcinoma detection and to the precursors thereof provoked by human papilloma virus or associated therewith, a diagnosis being based on corporal samples. The inventive method consists in determining the existence of the viral protein of the human papilloma virus. Said viral protein is embodied in the form of a capsid protein, in particular the major L1 capsid protein. A test kid for carrying out said method is also disclosed.
PCT/EP2004/003044 2003-03-25 2004-03-23 Method for early carcinoma detection and a test kit for carrying our said method WO2004085683A2 (en)

Priority Applications (2)

Application Number Priority Date Filing Date Title
EP04722574A EP1656561A2 (en) 2003-03-25 2004-03-23 Method for early carcinoma detection and a test kit for carrying out said method
JP2006504811A JP2006521104A (en) 2003-03-25 2004-03-23 Method for early diagnosis of carcinoma and test kit for performing the same

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE10313388 2003-03-25
DE10313388.7 2003-03-25

Publications (2)

Publication Number Publication Date
WO2004085683A2 WO2004085683A2 (en) 2004-10-07
WO2004085683A3 true WO2004085683A3 (en) 2005-01-06

Family

ID=33038757

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/EP2004/003044 WO2004085683A2 (en) 2003-03-25 2004-03-23 Method for early carcinoma detection and a test kit for carrying our said method

Country Status (3)

Country Link
EP (1) EP1656561A2 (en)
JP (1) JP2006521104A (en)
WO (1) WO2004085683A2 (en)

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8859218B2 (en) 2008-06-13 2014-10-14 Oncohealth Corp. In situ detection of early stages and late stages HPV infection
US8916342B2 (en) 2006-11-13 2014-12-23 Oncohealth Corp. Identification of high grade or ≧ CIN2 for early stages and late stages detection, screening, and diagnosis of human papillomavirus (HPV) and HPV-associated cancers
US8968995B2 (en) 2008-11-12 2015-03-03 Oncohealth Corp. Detection, screening, and diagnosis of HPV-associated cancers
US9128094B2 (en) 2010-01-08 2015-09-08 Oncohealth Corp. High throughput cell-based HPV immunoassays for diagnosis and screening of HPV-associated cancers

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1936379A1 (en) * 2006-12-21 2008-06-25 BUCHNER, Erwin Method for the detection of active hpv infection in biological samples by a sandwich enzyme-linked immunosorbent assay and test kit for performing the method
WO2009059325A2 (en) * 2007-11-02 2009-05-07 The Johns Hopkins University Multitype hpv peptide compositions and methods for treatment or prevention of human papillomavirus infection

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE4332596A1 (en) * 1993-09-24 1995-03-30 Martin Josef Dr Sapp Monoclonal antibodies
US5985610A (en) * 1992-09-03 1999-11-16 The United States Of America As Represented By The Department Of Health And Human Services Self-assembling recombinant papillomavirus capsid proteins
US6165471A (en) * 1997-07-03 2000-12-26 University Of Colorado, University Technology Corporation Homogeneous human papillomavirus capsomere containing compositions, methods for manufacture, and use thereof as diagnostic, prophylactic or therapeutic agents
WO2003020975A2 (en) * 2001-08-31 2003-03-13 Norchip A/S OLIGONUCLEOTIDES FOR USE IN DETECTION OF HUMAN PAPILLOMAVIRUS L1 mRNA

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5985610A (en) * 1992-09-03 1999-11-16 The United States Of America As Represented By The Department Of Health And Human Services Self-assembling recombinant papillomavirus capsid proteins
DE4332596A1 (en) * 1993-09-24 1995-03-30 Martin Josef Dr Sapp Monoclonal antibodies
US6165471A (en) * 1997-07-03 2000-12-26 University Of Colorado, University Technology Corporation Homogeneous human papillomavirus capsomere containing compositions, methods for manufacture, and use thereof as diagnostic, prophylactic or therapeutic agents
WO2003020975A2 (en) * 2001-08-31 2003-03-13 Norchip A/S OLIGONUCLEOTIDES FOR USE IN DETECTION OF HUMAN PAPILLOMAVIRUS L1 mRNA

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
MCMURRAY H R ET AL: "Biology of human papillomaviruses", INTERNATIONAL JOURNAL OF EXPERIMENTAL PATHOLOGY, vol. 82, no. 1, February 2001 (2001-02-01), pages 15 - 33, XP002301425, ISSN: 0959-9673 *

Cited By (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8916342B2 (en) 2006-11-13 2014-12-23 Oncohealth Corp. Identification of high grade or ≧ CIN2 for early stages and late stages detection, screening, and diagnosis of human papillomavirus (HPV) and HPV-associated cancers
US8859218B2 (en) 2008-06-13 2014-10-14 Oncohealth Corp. In situ detection of early stages and late stages HPV infection
US8865162B2 (en) 2008-06-13 2014-10-21 Oncohealth Corp. Monoclonal antibodies against HPV proteins
US9568474B2 (en) 2008-06-13 2017-02-14 Oncohealth Corp. In situ detection of early stages and late stages HPV infection
US8968995B2 (en) 2008-11-12 2015-03-03 Oncohealth Corp. Detection, screening, and diagnosis of HPV-associated cancers
US9128094B2 (en) 2010-01-08 2015-09-08 Oncohealth Corp. High throughput cell-based HPV immunoassays for diagnosis and screening of HPV-associated cancers

Also Published As

Publication number Publication date
WO2004085683A2 (en) 2004-10-07
EP1656561A2 (en) 2006-05-17
JP2006521104A (en) 2006-09-21

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