WO2004083367A3 - Lyophilised cells and a method of lyophilisation for the production of said cells - Google Patents

Lyophilised cells and a method of lyophilisation for the production of said cells Download PDF

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Publication number
WO2004083367A3
WO2004083367A3 PCT/FR2004/000561 FR2004000561W WO2004083367A3 WO 2004083367 A3 WO2004083367 A3 WO 2004083367A3 FR 2004000561 W FR2004000561 W FR 2004000561W WO 2004083367 A3 WO2004083367 A3 WO 2004083367A3
Authority
WO
WIPO (PCT)
Prior art keywords
cells
production
lyophilised
lyophilisation
relates
Prior art date
Application number
PCT/FR2004/000561
Other languages
French (fr)
Other versions
WO2004083367A2 (en
Inventor
Jean Gabert
John Saldanha
Peter Phillips
Original Assignee
Univ Aix Marseille Ii
Inst Nat De Controles Et De St
Jean Gabert
John Saldanha
Peter Phillips
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Aix Marseille Ii, Inst Nat De Controles Et De St, Jean Gabert, John Saldanha, Peter Phillips filed Critical Univ Aix Marseille Ii
Publication of WO2004083367A2 publication Critical patent/WO2004083367A2/en
Publication of WO2004083367A3 publication Critical patent/WO2004083367A3/en

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00—Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/04—Preserving or maintaining viable microorganisms
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6813—Hybridisation assays
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6844—Nucleic acid amplification reactions

Abstract

The invention relates to non-living lyophilised cells from prokaryotic or eukaryotic organisms and the use thereof as standards or controls for the assay of intra-cellular nucleic acid sequences (RNA or DNA), the epigenetic modifications and the products (proteins etc.) thereof. The invention further relates to a method applied to the production of said cells.
PCT/FR2004/000561 2003-03-14 2004-03-11 Lyophilised cells and a method of lyophilisation for the production of said cells WO2004083367A2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR0303199A FR2852329A1 (en) 2003-03-14 2003-03-14 Using dead, lyophilized cells as analytical controls, useful e.g. for determining intracellular nucleic acids, in clinical samples and for tracing transgenic organisms
FR0303199 2003-03-14

Publications (2)

Publication Number Publication Date
WO2004083367A2 WO2004083367A2 (en) 2004-09-30
WO2004083367A3 true WO2004083367A3 (en) 2004-11-11

Family

ID=32893319

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/FR2004/000561 WO2004083367A2 (en) 2003-03-14 2004-03-11 Lyophilised cells and a method of lyophilisation for the production of said cells

Country Status (2)

Country Link
FR (1) FR2852329A1 (en)
WO (1) WO2004083367A2 (en)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN111163789B (en) * 2017-07-11 2024-04-09 通用稳定技术公司 Method for preserving biopharmaceuticals

Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1990004329A1 (en) * 1988-10-20 1990-05-03 Coulter Corporation Stabilized lyophilized mammalian cells and method of making same
WO1992011864A1 (en) * 1991-01-11 1992-07-23 Cryopharm Corporation Method of detecting circulating antibody types using dried or lyophilized cells or cell-like material
WO1994029691A1 (en) * 1993-06-08 1994-12-22 Coulter Corporation Preserved, non-infectious control cells prepared by the modulation or modification of normal cells
WO1999000521A1 (en) * 1997-06-27 1999-01-07 Bio-Rad Laboratories Lyophilization of cultured human cells to preserve rna and dna
US20010051344A1 (en) * 1994-06-17 2001-12-13 Shalon Tidhar Dari Methods for constructing subarrays and uses thereof
US20020192645A1 (en) * 1999-12-24 2002-12-19 Tseng Richard W. BCR-ABL gene rearrangement assay method

Patent Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1990004329A1 (en) * 1988-10-20 1990-05-03 Coulter Corporation Stabilized lyophilized mammalian cells and method of making same
WO1992011864A1 (en) * 1991-01-11 1992-07-23 Cryopharm Corporation Method of detecting circulating antibody types using dried or lyophilized cells or cell-like material
WO1994029691A1 (en) * 1993-06-08 1994-12-22 Coulter Corporation Preserved, non-infectious control cells prepared by the modulation or modification of normal cells
US20010051344A1 (en) * 1994-06-17 2001-12-13 Shalon Tidhar Dari Methods for constructing subarrays and uses thereof
WO1999000521A1 (en) * 1997-06-27 1999-01-07 Bio-Rad Laboratories Lyophilization of cultured human cells to preserve rna and dna
US20020192645A1 (en) * 1999-12-24 2002-12-19 Tseng Richard W. BCR-ABL gene rearrangement assay method

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
BLOOD, vol. 102, no. 11, 16 November 2003 (2003-11-16), 45TH ANNUAL MEETING OF THE AMERICAN SOCIETY OF HEMATOLOGY; SAN DIEGO, CA, USA; DECEMBER 06-09, 2003, pages 373a - 374a, ISSN: 0006-4971 *
DATABASE BIOSIS [online] BIOSCIENCES INFORMATION SERVICE, PHILADELPHIA, PA, US; 16 November 2003 (2003-11-16), GABERT JEAN ET AL: "Biological reference materials for BCR ABL RNA detection by RQ PCR assays for therapeutic monitoring and optimization.", XP002295879, Database accession no. PREV200400133864 *

Also Published As

Publication number Publication date
FR2852329A1 (en) 2004-09-17
WO2004083367A2 (en) 2004-09-30

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