WO2004065938A3 - Human osteoporosis gene - Google Patents

Human osteoporosis gene Download PDF

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Publication number
WO2004065938A3
WO2004065938A3 PCT/US2004/000990 US2004000990W WO2004065938A3 WO 2004065938 A3 WO2004065938 A3 WO 2004065938A3 US 2004000990 W US2004000990 W US 2004000990W WO 2004065938 A3 WO2004065938 A3 WO 2004065938A3
Authority
WO
WIPO (PCT)
Prior art keywords
osteoporosis
gene
human osteoporosis
human
disclosed
Prior art date
Application number
PCT/US2004/000990
Other languages
French (fr)
Other versions
WO2004065938A2 (en
Inventor
Unnur Styrkarsdottir
Vala Drofn Johannsdottir
Jeffrey R Gulcher
Original Assignee
Decode Genetics Ehf
Unnur Styrkarsdottir
Vala Drofn Johannsdottir
Jeffrey R Gulcher
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US09/661,887 external-priority patent/US6630304B1/en
Priority claimed from US10/346,723 external-priority patent/US20030176344A1/en
Application filed by Decode Genetics Ehf, Unnur Styrkarsdottir, Vala Drofn Johannsdottir, Jeffrey R Gulcher filed Critical Decode Genetics Ehf
Priority to CA002512239A priority Critical patent/CA2512239A1/en
Priority to EP04702489A priority patent/EP1585837A2/en
Priority to JP2006500965A priority patent/JP2006515992A/en
Publication of WO2004065938A2 publication Critical patent/WO2004065938A2/en
Publication of WO2004065938A3 publication Critical patent/WO2004065938A3/en
Priority to US11/185,033 priority patent/US20060057612A1/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/156—Polymorphic or mutational markers

Abstract

A role of the human BMP2 nucleic acid in osteoporosis is disclosed. Methods for diagnosis, prediction of clinical course and treatment for osteoporosis or a susceptibility to osteoporosis using polymorphisms in the BMP2 nucleic acid, alone or in combination with other assays, are also disclosed.
PCT/US2004/000990 2000-09-14 2004-01-15 Human osteoporosis gene WO2004065938A2 (en)

Priority Applications (4)

Application Number Priority Date Filing Date Title
CA002512239A CA2512239A1 (en) 2003-01-16 2004-01-15 Human osteoporosis gene
EP04702489A EP1585837A2 (en) 2003-01-16 2004-01-15 Human osteoporosis gene
JP2006500965A JP2006515992A (en) 2003-01-16 2004-01-15 Human osteoporosis gene
US11/185,033 US20060057612A1 (en) 2000-09-14 2005-07-18 Methods for diagnosing osteoporosis or a susceptibility to osteoporosis based on haplotype association

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US09/661,887 US6630304B1 (en) 2000-09-14 2000-09-14 Human osteoporosis gene
PCT/IB2001/001667 WO2002022871A2 (en) 2000-09-14 2001-09-12 Polymorphic bone morphogenetic protein 2
US09/952,360 US20020072066A1 (en) 2000-09-14 2001-09-13 Human osteoporosis gene
US10/346,723 US20030176344A1 (en) 2000-09-14 2003-01-16 Human osteoporosis gene
US10/346,723 2003-01-16

Related Child Applications (1)

Application Number Title Priority Date Filing Date
US11/185,033 Continuation-In-Part US20060057612A1 (en) 2000-09-14 2005-07-18 Methods for diagnosing osteoporosis or a susceptibility to osteoporosis based on haplotype association

Publications (2)

Publication Number Publication Date
WO2004065938A2 WO2004065938A2 (en) 2004-08-05
WO2004065938A3 true WO2004065938A3 (en) 2004-10-28

Family

ID=56290520

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2004/000990 WO2004065938A2 (en) 2000-09-14 2004-01-15 Human osteoporosis gene

Country Status (1)

Country Link
WO (1) WO2004065938A2 (en)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2004065939A2 (en) * 2003-01-16 2004-08-05 Decode Genetics Ehf. Methods for diagnosing osteoporosis or a susceptibility to osteoporosis based on haplotype association
WO2010073266A1 (en) * 2008-12-23 2010-07-01 Decode Genetics Ehf Sequence variants predictive of risk of kidney stones and bone mineral density

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2002022871A2 (en) * 2000-09-14 2002-03-21 Decode Genetics Ehf Polymorphic bone morphogenetic protein 2

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2002022871A2 (en) * 2000-09-14 2002-03-21 Decode Genetics Ehf Polymorphic bone morphogenetic protein 2

Also Published As

Publication number Publication date
WO2004065938A2 (en) 2004-08-05

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