WO2004064708A2 - Solution for nostril wash - Google Patents

Solution for nostril wash Download PDF

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Publication number
WO2004064708A2
WO2004064708A2 PCT/BR2003/000181 BR0300181W WO2004064708A2 WO 2004064708 A2 WO2004064708 A2 WO 2004064708A2 BR 0300181 W BR0300181 W BR 0300181W WO 2004064708 A2 WO2004064708 A2 WO 2004064708A2
Authority
WO
WIPO (PCT)
Prior art keywords
nostril
solution
wash
diseases
chloride
Prior art date
Application number
PCT/BR2003/000181
Other languages
French (fr)
Other versions
WO2004064708A3 (en
Inventor
Erika Yokoingawa Camargo Viertler
Original Assignee
Viertler Erika Yokoingawa Cama
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Viertler Erika Yokoingawa Cama filed Critical Viertler Erika Yokoingawa Cama
Priority to EP03815343A priority Critical patent/EP1589946A2/en
Publication of WO2004064708A2 publication Critical patent/WO2004064708A2/en
Publication of WO2004064708A3 publication Critical patent/WO2004064708A3/en

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Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0043Nose
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/70Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7004Monosaccharides having only carbon, hydrogen and oxygen atoms
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00Medicinal preparations containing inorganic active ingredients
    • A61K33/14Alkali metal chlorides; Alkaline earth metal chlorides
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • A61P11/02Nasal agents, e.g. decongestants

Definitions

  • the presented solution consists of a therapy supporting of the diseases nostril (rinites, sinusites, allergies, etc.) and powders-operative of nostril surgeries.
  • the nostril wash seeks to improve the patient's breathing, benefiting in the treatment of the nostril diseases.
  • the present object is destined to allow the hygiene of the nostril and coadjutant cavities, in the treatment of pathologies as rinorreia (mucous membrane and festering); rinites (infectious and obstructive vasomotor), sinusites and rinossinusites and powders- operative of nostril surgeries (aesthetics and reparative).
  • the allergic rinite is the most frequent of the diseases, could be seasonal, perennial and mixed (allergic and bacterial), being characterized by sneezes, limpid rinorreia or mucopurulenta. itch and nostril congestion, that can be accompanied of ocular and other symptoms.
  • the inflammatory process doesn't just affect the nostril cavity, but also copper the breasts nostril so that the morbidade not only it depends on the disease, but also of your complications: sinusite, dysfunction of Eustaquio's trumpet, alterations of the sleep (nostril congestion).
  • sinusite dysfunction of Eustaquio's trumpet
  • alterations of the sleep nostril congestion.
  • they are used the nostril washes frequently with saline solution (NaCl to 0,9%) and plus, now, the saline solutions with sea water, physiologic serum and solutions 1 with conserving.
  • saline solution NaCl to 0,9%

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Epidemiology (AREA)
  • Otolaryngology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pulmonology (AREA)
  • Inorganic Chemistry (AREA)
  • Organic Chemistry (AREA)
  • Molecular Biology (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)

Abstract

Refers the present invention, to an unpublished solution for the nostril wash, kindred of removing secretions, crusts and mucus, unblock the nostril cavity. The presented solution, it consists of a therapy supporting of the diseases nostril (rinites, sinusites, allergies, etc.) and powders-operative of nostril surgeries, through a solution composed of chloride of sodium, potassium chloride, glucose and distilled water, the nostril wash seeks to improve the patient’s breathing, benefiting in the treatment of the nostril diseases.

Description

Title: "SOLUTION FOR NOSTRIL WASH. " DESCRIPTION OF THE PATENT Refers the present invention, to an unpublished solution for the nostril wash, kindred of removing secretions, crusts and mucus, unblock the nostril cavity. The presented solution, it consists of a therapy supporting of the diseases nostril (rinites, sinusites, allergies, etc.) and powders-operative of nostril surgeries. Through a solution composed of chloride of sodium, potassium chloride, glucose and distilled water, the nostril wash seeks to improve the patient's breathing, benefiting in the treatment of the nostril diseases. The present object is destined to allow the hygiene of the nostril and coadjutant cavities, in the treatment of pathologies as rinorreia (mucous membrane and festering); rinites (infectious and obstructive vasomotor), sinusites and rinossinusites and powders- operative of nostril surgeries (aesthetics and reparative). The allergic rinite is the most frequent of the diseases, could be seasonal, perennial and mixed (allergic and bacterial), being characterized by sneezes, limpid rinorreia or mucopurulenta. itch and nostril congestion, that can be accompanied of ocular and other symptoms. The inflammatory process doesn't just affect the nostril cavity, but also copper the breasts nostril so that the morbidade not only it depends on the disease, but also of your complications: sinusite, dysfunction of Eustaquio's trumpet, alterations of the sleep (nostril congestion). In your conventional treatment, they are used the nostril washes frequently with saline solution (NaCl to 0,9%) and plus, now, the saline solutions with sea water, physiologic serum and solutions 1 with conserving. However, such solutions present in your majority,
2 collateral effects to the patients, being able to
3
4 to arrive to the compromising of the eyelashes of the mucous
5 membrane.
6 The solution for now presented, it doesn't possess conserving
7 and the cloret's used in your composition (KCI and NaCl) with the
8 glucose they are component found in the human blood (it shapes) and
9 also in the nostril cavity, in other words, it is a closer solution of the lo physiologic, being also a solution hypertonic, however without causing ii the adverse collateral effects in the nostril mucous membranes, plus,
12 only the longed for benefits, such as: the unblock of the passage of the
13 air for the nostril cavity, benefiting in the treatment of the diseases.
14 The percentile ones used in the solution, they were equation is the starting from studies and tests accomplished in small animals ie (guinea-pigs), aiming at a solution to reach the benefits of the nostril 17 wash, however without causing adverse effects to the patients. It is a is solution more hypertonica than the physiologic serum, however without
19 reaching high tonic indexes, seeking a better clinical use of the
20 patients.
2i In the accomplished study, it was verified that the continuous
22 use of the physiologic serum can cause an effect it bounces of
23 increase in the production in the mucus and that the continuous use of
24 the presented solution, didn't cause the collateral effects presented by
25 the serum. Besides, this solution doesn't present conserve, which more
26 it approximates her/it of the physiologic, however, it should come
27 conditioned tightly in disposable and closed flasks to avoid the infection
28 possibility for bacterial that are proliferated in habitat the glucose base. i The study was for the percentile of the composition of each
2 component, so that if it reached an appropriate solution for the
3 expected objective. Your composition is made of chloride of sodium (NaCl) to 1,2%, mixed with potassium chloride (KCI) to 0,03%,
5 mixed with glucose to 1% and water distilled to 100ml.
6 In agreement with the description and in your details, the
7 "SOLUTION FOR NOSTRIL WASH," for now in subject, it is s characterized by being constituted of a solution for nostril wash (1), 9 possessing a composition of chloride of sodium (NaCl) to 1,2% (2), o mixed with potassium chloride (KCI) to 0,03% (3), mixed with glucose i to 1% (4) and water distilled to 100ml (5), to be conditioned in flasks 2 closed tightly and you discarded (6). s For the advantages that offers and for covering truly of 4 characteristics innovative, the "SOLUTION FOR NOSTRIL WASH.", it s gathers the necessary conditions to deserve the Privilege of Patent of 6 Invention.

Claims

CLAIMS 1a) "SOLUTION FOR NOSTRIL WASH.", characterized by being constituted of a solution for nostril wash (1), possessing a composition of chloride of sodium (NaCl) to 1,2% (2), mixed with potassium chloride (KCI) to 0,03% (3), mixed with glucose to 1% (4) and water distilled to 100ml (5), to be conditioned in flasks closed tightly and you discarded (6).
PCT/BR2003/000181 2003-01-23 2003-12-02 Solution for nostril wash WO2004064708A2 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
EP03815343A EP1589946A2 (en) 2003-01-23 2003-12-02 Solution for nostril wash

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
BRPI0301165-8 2003-01-23
BR0301165-8A BR0301165A (en) 2003-01-23 2003-01-23 Nasal wash solution

Publications (2)

Publication Number Publication Date
WO2004064708A2 true WO2004064708A2 (en) 2004-08-05
WO2004064708A3 WO2004064708A3 (en) 2004-09-23

Family

ID=32739200

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/BR2003/000181 WO2004064708A2 (en) 2003-01-23 2003-12-02 Solution for nostril wash

Country Status (3)

Country Link
EP (1) EP1589946A2 (en)
BR (1) BR0301165A (en)
WO (1) WO2004064708A2 (en)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2017126857A1 (en) * 2016-01-19 2017-07-27 정호철 Nasal cleaner

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3815360A1 (en) * 1988-05-05 1989-11-16 Dibbert Hans Juergen Dr Med Use of an aqueous glucose solution as medium for rinsing the nasal and/or pharyngeal space
EP0520112A1 (en) * 1990-02-15 1992-12-30 CAC Corporation Dermatological composition based on an aqueous phase
WO2000001395A1 (en) * 1998-07-03 2000-01-13 Laboratoires Goemar S.A. Hypo-osmotic saline solutions, method for preparing same and medicines based on said solutions

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3815360A1 (en) * 1988-05-05 1989-11-16 Dibbert Hans Juergen Dr Med Use of an aqueous glucose solution as medium for rinsing the nasal and/or pharyngeal space
EP0520112A1 (en) * 1990-02-15 1992-12-30 CAC Corporation Dermatological composition based on an aqueous phase
WO2000001395A1 (en) * 1998-07-03 2000-01-13 Laboratoires Goemar S.A. Hypo-osmotic saline solutions, method for preparing same and medicines based on said solutions

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2017126857A1 (en) * 2016-01-19 2017-07-27 정호철 Nasal cleaner
KR101770752B1 (en) * 2016-01-19 2017-08-24 정호철 nasal cavity cleaner

Also Published As

Publication number Publication date
EP1589946A2 (en) 2005-11-02
BR0301165A (en) 2005-05-10
WO2004064708A3 (en) 2004-09-23

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