WO2004062640A3 - Capsule for receiving an active substance which is administrable by inhalation - Google Patents

Capsule for receiving an active substance which is administrable by inhalation Download PDF

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Publication number
WO2004062640A3
WO2004062640A3 PCT/EP2003/014694 EP0314694W WO2004062640A3 WO 2004062640 A3 WO2004062640 A3 WO 2004062640A3 EP 0314694 W EP0314694 W EP 0314694W WO 2004062640 A3 WO2004062640 A3 WO 2004062640A3
Authority
WO
WIPO (PCT)
Prior art keywords
capsule
administrable
inhalation
receiving
active substance
Prior art date
Application number
PCT/EP2003/014694
Other languages
German (de)
French (fr)
Other versions
WO2004062640A2 (en
Inventor
Dieter Hochrainer
Heinrich Kladders
Burkhard Metzger
Original Assignee
Boehringer Ingelheim Int
Dieter Hochrainer
Heinrich Kladders
Burkhard Metzger
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Boehringer Ingelheim Int, Dieter Hochrainer, Heinrich Kladders, Burkhard Metzger filed Critical Boehringer Ingelheim Int
Priority to CA2513201A priority Critical patent/CA2513201C/en
Priority to EP03799497A priority patent/EP1587564A2/en
Priority to JP2004566013A priority patent/JP2006517421A/en
Priority to AU2003300220A priority patent/AU2003300220A1/en
Publication of WO2004062640A2 publication Critical patent/WO2004062640A2/en
Publication of WO2004062640A3 publication Critical patent/WO2004062640A3/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/007—Pulmonary tract; Aromatherapy
    • A61K9/0073—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
    • A61K9/0075—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy for inhalation via a dry powder inhaler [DPI], e.g. comprising micronized drug mixed with lactose carrier particles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4808—Preparations in capsules, e.g. of gelatin, of chocolate characterised by the form of the capsule or the structure of the filling; Capsules containing small tablets; Capsules with outer layer for immediate drug release
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00—Inhalators
    • A61M15/0028—Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up
    • A61M15/003—Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up using capsules, e.g. to be perforated or broken-up
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00—Inhalators
    • A61M15/0028—Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up
    • A61M15/003—Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up using capsules, e.g. to be perforated or broken-up
    • A61M15/0033—Details of the piercing or cutting means
    • A61M15/0035—Piercing means
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00—Inhalators
    • A61M15/0028—Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up
    • A61M15/0045—Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up using multiple prepacked dosages on a same carrier, e.g. blisters
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00—Inhalators
    • A61M15/0028—Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up
    • A61M15/0045—Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up using multiple prepacked dosages on a same carrier, e.g. blisters
    • A61M15/0046—Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up using multiple prepacked dosages on a same carrier, e.g. blisters characterized by the type of carrier
    • A61M15/0048—Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up using multiple prepacked dosages on a same carrier, e.g. blisters characterized by the type of carrier the dosages being arranged in a plane, e.g. on diskettes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2202/00—Special media to be introduced, removed or treated
    • A61M2202/06—Solids
    • A61M2202/064—Powder

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pulmonology (AREA)
  • Biomedical Technology (AREA)
  • Hematology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Anesthesiology (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Otolaryngology (AREA)
  • Medical Preparation Storing Or Oral Administration Devices (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Containers And Packaging Bodies Having A Special Means To Remove Contents (AREA)

Abstract

The invention relates to a novel capsule for receiving an active substance which is administrable by inhalation. The inventive capsule is preferably used for powder inhalators operating according to Bernoulli's principle.
PCT/EP2003/014694 2003-01-14 2003-12-20 Capsule for receiving an active substance which is administrable by inhalation WO2004062640A2 (en)

Priority Applications (4)

Application Number Priority Date Filing Date Title
CA2513201A CA2513201C (en) 2003-01-14 2003-12-20 Capsule for receiving an active substance which is administrable by inhalation
EP03799497A EP1587564A2 (en) 2003-01-14 2003-12-20 Capsule for receiving an active substance which is administrable by inhalation
JP2004566013A JP2006517421A (en) 2003-01-14 2003-12-20 Capsules for receiving active substances administered by inhalation
AU2003300220A AU2003300220A1 (en) 2003-01-14 2003-12-20 Capsule for receiving an active substance which is administrable by inhalation

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE10300984.1 2003-01-14
DE2003100984 DE10300984A1 (en) 2003-01-14 2003-01-14 Capsule for taking up an active ingredient that can be administered by inhalation

Publications (2)

Publication Number Publication Date
WO2004062640A2 WO2004062640A2 (en) 2004-07-29
WO2004062640A3 true WO2004062640A3 (en) 2004-10-21

Family

ID=32519907

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/EP2003/014694 WO2004062640A2 (en) 2003-01-14 2003-12-20 Capsule for receiving an active substance which is administrable by inhalation

Country Status (6)

Country Link
EP (1) EP1587564A2 (en)
JP (1) JP2006517421A (en)
AU (1) AU2003300220A1 (en)
CA (1) CA2513201C (en)
DE (1) DE10300984A1 (en)
WO (1) WO2004062640A2 (en)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE102007036411A1 (en) * 2007-07-20 2009-02-12 Boehringer Ingelheim Pharma Gmbh & Co. Kg powder inhaler
TR200803525A2 (en) * 2008-05-16 2009-12-21 Bi̇lgi̇ç Mahmut Powder inhaler.
JP5415341B2 (en) * 2010-03-31 2014-02-12 株式会社吉野工業所 Powder inhalation device
JP6037315B2 (en) * 2011-05-27 2016-12-07 ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング Inhaler and capsule for inhaler
PT107627B (en) * 2014-04-29 2017-03-08 Hovione Farmaciência S A HINGE CAPSULE INHALER WITH HINGE
EP3167868A1 (en) * 2015-11-16 2017-05-17 Capsugel Belgium NV Tamperproof dosage form
EP3167867A1 (en) * 2015-11-16 2017-05-17 Capsugel Belgium NV Tamperproof dosage form
CN111012671B (en) * 2019-11-25 2022-07-05 上海强德食品科技有限公司 Physical preparation method of microcapsule

Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0143524A1 (en) * 1983-09-23 1985-06-05 Lilly Industries Limited Two-part capsule
DE3927170A1 (en) * 1989-08-17 1991-02-21 Boehringer Ingelheim Kg INHALATOR
EP0911047A1 (en) * 1993-06-03 1999-04-28 Boehringer Ingelheim Pharma KG Capsule holder
DE19835346A1 (en) * 1998-08-05 2000-02-10 Boehringer Ingelheim Pharma Two-part capsule for pharmaceutical preparations for powder inhalers
GB2356842A (en) * 1999-11-17 2001-06-06 Aquasol Ltd Injection-moulded capsules

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE395611B (en) * 1975-12-12 1977-08-22 Draco Ab AEROSOL INHALATION DEVICE INTENDED FOR INHALATION THROUGH AN INHALATION MOUTH OF PHARMACOLOGICALLY ACTIVE SUBSTANCES
DE3345722A1 (en) * 1983-12-17 1985-06-27 Boehringer Ingelheim KG, 6507 Ingelheim INHALATOR
AU650953B2 (en) * 1991-03-21 1994-07-07 Novartis Ag Inhaler
JP3372105B2 (en) * 1994-05-26 2003-01-27 株式会社日立ユニシアオートモティブ Inhalation type dispenser

Patent Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0143524A1 (en) * 1983-09-23 1985-06-05 Lilly Industries Limited Two-part capsule
DE3927170A1 (en) * 1989-08-17 1991-02-21 Boehringer Ingelheim Kg INHALATOR
EP0911047A1 (en) * 1993-06-03 1999-04-28 Boehringer Ingelheim Pharma KG Capsule holder
DE19835346A1 (en) * 1998-08-05 2000-02-10 Boehringer Ingelheim Pharma Two-part capsule for pharmaceutical preparations for powder inhalers
WO2000007572A2 (en) * 1998-08-05 2000-02-17 Boehringer Ingelheim Pharma Kg Two-piece capsule for receiving pharmaceutical preparations for powder inhalers
GB2356842A (en) * 1999-11-17 2001-06-06 Aquasol Ltd Injection-moulded capsules

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
See also references of EP1587564A2 *

Also Published As

Publication number Publication date
JP2006517421A (en) 2006-07-27
AU2003300220A8 (en) 2004-08-10
CA2513201A1 (en) 2004-07-29
AU2003300220A1 (en) 2004-08-10
DE10300984A1 (en) 2004-07-22
EP1587564A2 (en) 2005-10-26
WO2004062640A2 (en) 2004-07-29
CA2513201C (en) 2012-10-02

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