WO2004060446A3 - Procede et appareil d'utilisation de techniques optiques pour mesurer des taux d'analyte - Google Patents

Procede et appareil d'utilisation de techniques optiques pour mesurer des taux d'analyte Download PDF

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Publication number
WO2004060446A3
WO2004060446A3 PCT/US2003/041702 US0341702W WO2004060446A3 WO 2004060446 A3 WO2004060446 A3 WO 2004060446A3 US 0341702 W US0341702 W US 0341702W WO 2004060446 A3 WO2004060446 A3 WO 2004060446A3
Authority
WO
WIPO (PCT)
Prior art keywords
cartridge
analyte
detecting members
analyte levels
analyte detecting
Prior art date
Application number
PCT/US2003/041702
Other languages
English (en)
Other versions
WO2004060446A2 (fr
Inventor
Dominique M Freeman
Dirk Boecker
Robert Jones
David Cullen
Malcolm Mcleod
William Carlsen
Michael J Owen
Christopher Dryer
Original Assignee
Pelikan Technologies Inc
Dominique M Freeman
Dirk Boecker
Robert Jones
David Cullen
Malcolm Mcleod
William Carlsen
Michael J Owen
Christopher Dryer
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pelikan Technologies Inc, Dominique M Freeman, Dirk Boecker, Robert Jones, David Cullen, Malcolm Mcleod, William Carlsen, Michael J Owen, Christopher Dryer filed Critical Pelikan Technologies Inc
Priority to EP03800394A priority Critical patent/EP1585978A4/fr
Priority to US10/541,124 priority patent/US8574895B2/en
Priority to AU2003300136A priority patent/AU2003300136A1/en
Publication of WO2004060446A2 publication Critical patent/WO2004060446A2/fr
Publication of WO2004060446A3 publication Critical patent/WO2004060446A3/fr
Priority to US13/532,927 priority patent/US9034639B2/en

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/145Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue
    • A61B5/14532Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue for measuring glucose, e.g. by tissue impedance measurement
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/15Devices for taking samples of blood
    • A61B5/150007Details
    • A61B5/150015Source of blood
    • A61B5/150022Source of blood for capillary blood or interstitial fluid
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/15Devices for taking samples of blood
    • A61B5/150007Details
    • A61B5/150053Details for enhanced collection of blood or interstitial fluid at the sample site, e.g. by applying compression, heat, vibration, ultrasound, suction or vacuum to tissue; for reduction of pain or discomfort; Skin piercing elements, e.g. blades, needles, lancets or canulas, with adjustable piercing speed
    • A61B5/150106Means for reducing pain or discomfort applied before puncturing; desensitising the skin at the location where body is to be pierced
    • A61B5/150152Means for reducing pain or discomfort applied before puncturing; desensitising the skin at the location where body is to be pierced by an adequate mechanical impact on the puncturing location
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/15Devices for taking samples of blood
    • A61B5/150007Details
    • A61B5/150053Details for enhanced collection of blood or interstitial fluid at the sample site, e.g. by applying compression, heat, vibration, ultrasound, suction or vacuum to tissue; for reduction of pain or discomfort; Skin piercing elements, e.g. blades, needles, lancets or canulas, with adjustable piercing speed
    • A61B5/150167Adjustable piercing speed of skin piercing element, e.g. blade, needle, lancet or canula, for example with varying spring force or pneumatic drive
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/15Devices for taking samples of blood
    • A61B5/150007Details
    • A61B5/150175Adjustment of penetration depth
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/15Devices for taking samples of blood
    • A61B5/150007Details
    • A61B5/150206Construction or design features not otherwise provided for; manufacturing or production; packages; sterilisation of piercing element, piercing device or sampling device
    • A61B5/150274Manufacture or production processes or steps for blood sampling devices
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/15Devices for taking samples of blood
    • A61B5/150007Details
    • A61B5/150358Strips for collecting blood, e.g. absorbent
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/15Devices for taking samples of blood
    • A61B5/150007Details
    • A61B5/150374Details of piercing elements or protective means for preventing accidental injuries by such piercing elements
    • A61B5/150381Design of piercing elements
    • A61B5/150412Pointed piercing elements, e.g. needles, lancets for piercing the skin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/15Devices for taking samples of blood
    • A61B5/151Devices specially adapted for taking samples of capillary blood, e.g. by lancets, needles or blades
    • A61B5/15101Details
    • A61B5/15103Piercing procedure
    • A61B5/15107Piercing being assisted by a triggering mechanism
    • A61B5/15113Manually triggered, i.e. the triggering requires a deliberate action by the user such as pressing a drive button
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/15Devices for taking samples of blood
    • A61B5/151Devices specially adapted for taking samples of capillary blood, e.g. by lancets, needles or blades
    • A61B5/15101Details
    • A61B5/15115Driving means for propelling the piercing element to pierce the skin, e.g. comprising mechanisms based on shape memory alloys, magnetism, solenoids, piezoelectric effect, biased elements, resilient elements, vacuum or compressed fluids
    • A61B5/15123Driving means for propelling the piercing element to pierce the skin, e.g. comprising mechanisms based on shape memory alloys, magnetism, solenoids, piezoelectric effect, biased elements, resilient elements, vacuum or compressed fluids comprising magnets or solenoids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/15Devices for taking samples of blood
    • A61B5/151Devices specially adapted for taking samples of capillary blood, e.g. by lancets, needles or blades
    • A61B5/15146Devices loaded with multiple lancets simultaneously, e.g. for serial firing without reloading, for example by use of stocking means.
    • A61B5/15148Constructional features of stocking means, e.g. strip, roll, disc, cartridge, belt or tube
    • A61B5/15149Arrangement of piercing elements relative to each other
    • A61B5/15151Each piercing element being stocked in a separate isolated compartment
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/15Devices for taking samples of blood
    • A61B5/151Devices specially adapted for taking samples of capillary blood, e.g. by lancets, needles or blades
    • A61B5/15146Devices loaded with multiple lancets simultaneously, e.g. for serial firing without reloading, for example by use of stocking means.
    • A61B5/15148Constructional features of stocking means, e.g. strip, roll, disc, cartridge, belt or tube
    • A61B5/15157Geometry of stocking means or arrangement of piercing elements therein
    • A61B5/15159Piercing elements stocked in or on a disc
    • A61B5/15161Characterized by propelling the piercing element in a radial direction relative to the disc
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/15Devices for taking samples of blood
    • A61B5/151Devices specially adapted for taking samples of capillary blood, e.g. by lancets, needles or blades
    • A61B5/15146Devices loaded with multiple lancets simultaneously, e.g. for serial firing without reloading, for example by use of stocking means.
    • A61B5/15148Constructional features of stocking means, e.g. strip, roll, disc, cartridge, belt or tube
    • A61B5/15157Geometry of stocking means or arrangement of piercing elements therein
    • A61B5/15165Piercing elements stocked in or on a strip
    • A61B5/15169Characterized by a rolled strip
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/15Devices for taking samples of blood
    • A61B5/151Devices specially adapted for taking samples of capillary blood, e.g. by lancets, needles or blades
    • A61B5/15146Devices loaded with multiple lancets simultaneously, e.g. for serial firing without reloading, for example by use of stocking means.
    • A61B5/15148Constructional features of stocking means, e.g. strip, roll, disc, cartridge, belt or tube
    • A61B5/15157Geometry of stocking means or arrangement of piercing elements therein
    • A61B5/15165Piercing elements stocked in or on a strip
    • A61B5/15171Characterized by propelling the piercing element perpendicular to the direction of movement of the strip
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/15Devices for taking samples of blood
    • A61B5/151Devices specially adapted for taking samples of capillary blood, e.g. by lancets, needles or blades
    • A61B5/15146Devices loaded with multiple lancets simultaneously, e.g. for serial firing without reloading, for example by use of stocking means.
    • A61B5/15148Constructional features of stocking means, e.g. strip, roll, disc, cartridge, belt or tube
    • A61B5/15176Stocking means comprising cap, cover, sheath or protection for aseptic stocking
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/15Devices for taking samples of blood
    • A61B5/151Devices specially adapted for taking samples of capillary blood, e.g. by lancets, needles or blades
    • A61B5/15146Devices loaded with multiple lancets simultaneously, e.g. for serial firing without reloading, for example by use of stocking means.
    • A61B5/15182Means for keeping track or checking of the total number of piercing elements already used or the number of piercing elements still remaining in the stocking, e.g. by check window, counter, display
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/15Devices for taking samples of blood
    • A61B5/157Devices characterised by integrated means for measuring characteristics of blood
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/75Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated
    • G01N21/77Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated by observing the effect on a chemical indicator
    • G01N2021/7769Measurement method of reaction-produced change in sensor
    • G01N2021/7773Reflection
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/75Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated
    • G01N21/77Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated by observing the effect on a chemical indicator
    • G01N2021/7769Measurement method of reaction-produced change in sensor
    • G01N2021/7786Fluorescence
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/75Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated
    • G01N21/77Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated by observing the effect on a chemical indicator

Abstract

L'invention porte sur un dispositif destiné à être utilisé avec un système de pénétration de tissu et/ou un dispositif de mesure pour mesurer les taux d'analyte. Le dispositif comprend une cartouche et une pluralité d'éléments de détection d'analyte montés sur la cartouche. La cartouche peut avoir la forme d'un disque radial et peut également être dimensionnée de façon à s'adapter au dispositif de mesure. Les éléments de détection de l'analyte peuvent être un système optique utilisant une durée de vie de fluorescence pour déterminer les taux d'analyte. Selon une réalisation, le dispositif peut également comprendre un étaleur de fluide positionné sur au moins une partie de l'élément de détection de l'analyte de façon à pousser le fluide vers l'un de ces éléments de détection. Il est possible d'utiliser une pluralité d'éléments de détection d'analyte, chacun de ces éléments pouvant être un dispositif de petit volume.
PCT/US2003/041702 2002-12-30 2003-12-30 Procede et appareil d'utilisation de techniques optiques pour mesurer des taux d'analyte WO2004060446A2 (fr)

Priority Applications (4)

Application Number Priority Date Filing Date Title
EP03800394A EP1585978A4 (fr) 2002-12-30 2003-12-30 Procede et appareil d'utilisation de techniques optiques pour mesurer des taux d'analyte
US10/541,124 US8574895B2 (en) 2002-12-30 2003-12-30 Method and apparatus using optical techniques to measure analyte levels
AU2003300136A AU2003300136A1 (en) 2002-12-30 2003-12-30 Method and apparatus using optical techniques to measure analyte levels
US13/532,927 US9034639B2 (en) 2002-12-30 2012-06-26 Method and apparatus using optical techniques to measure analyte levels

Applications Claiming Priority (48)

Application Number Priority Date Filing Date Title
US43734102P 2002-12-30 2002-12-30
US43733702P 2002-12-30 2002-12-30
US43733502P 2002-12-30 2002-12-30
US43751002P 2002-12-30 2002-12-30
US43734302P 2002-12-30 2002-12-30
US43718602P 2002-12-30 2002-12-30
US43734702P 2002-12-30 2002-12-30
US43751402P 2002-12-30 2002-12-30
US43719202P 2002-12-30 2002-12-30
US43734502P 2002-12-30 2002-12-30
US43733302P 2002-12-30 2002-12-30
US43731202P 2002-12-30 2002-12-30
US43734202P 2002-12-30 2002-12-30
US43734602P 2002-12-30 2002-12-30
US43733402P 2002-12-30 2002-12-30
US43718502P 2002-12-30 2002-12-30
US43733602P 2002-12-30 2002-12-30
US43719102P 2002-12-30 2002-12-30
US43734002P 2002-12-30 2002-12-30
US43745402P 2002-12-30 2002-12-30
US43718402P 2002-12-30 2002-12-30
US43738602P 2002-12-30 2002-12-30
US43745502P 2002-12-30 2002-12-30
US60/437,454 2002-12-30
US60/437,386 2002-12-30
US60/437,191 2002-12-30
US60/437,337 2002-12-30
US60/437,334 2002-12-30
US60/437,340 2002-12-30
US60/437,342 2002-12-30
US60/437,192 2002-12-30
US60/437,347 2002-12-30
US60/437,455 2002-12-30
US60/437,333 2002-12-30
US60/437,514 2002-12-30
US60/437,184 2002-12-30
US60/437,341 2002-12-30
US60/437,185 2002-12-30
US60/437,346 2002-12-30
US60/437,510 2002-12-30
US60/437,312 2002-12-30
US60/437,335 2002-12-30
US60/437,336 2002-12-30
US60/437,343 2002-12-30
US60/437,186 2002-12-30
US60/437,345 2002-12-30
US43732302P 2002-12-31 2002-12-31
US60/437,323 2002-12-31

Related Child Applications (1)

Application Number Title Priority Date Filing Date
US13/532,927 Continuation US9034639B2 (en) 2002-12-30 2012-06-26 Method and apparatus using optical techniques to measure analyte levels

Publications (2)

Publication Number Publication Date
WO2004060446A2 WO2004060446A2 (fr) 2004-07-22
WO2004060446A3 true WO2004060446A3 (fr) 2004-09-30

Family

ID=32719849

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2003/041702 WO2004060446A2 (fr) 2002-12-30 2003-12-30 Procede et appareil d'utilisation de techniques optiques pour mesurer des taux d'analyte

Country Status (3)

Country Link
EP (1) EP1585978A4 (fr)
AU (1) AU2003300136A1 (fr)
WO (1) WO2004060446A2 (fr)

Cited By (13)

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Publication number Priority date Publication date Assignee Title
US8690796B2 (en) 2002-04-19 2014-04-08 Sanofi-Aventis Deutschland Gmbh Method and apparatus for penetrating tissue
US8845549B2 (en) 2002-04-19 2014-09-30 Sanofi-Aventis Deutschland Gmbh Method for penetrating tissue
US8845550B2 (en) 2001-06-12 2014-09-30 Sanofi-Aventis Deutschland Gmbh Tissue penetration device
US8905945B2 (en) 2002-04-19 2014-12-09 Dominique M. Freeman Method and apparatus for penetrating tissue
US8945910B2 (en) 2003-09-29 2015-02-03 Sanofi-Aventis Deutschland Gmbh Method and apparatus for an improved sample capture device
US8965476B2 (en) 2010-04-16 2015-02-24 Sanofi-Aventis Deutschland Gmbh Tissue penetration device
US9144401B2 (en) 2003-06-11 2015-09-29 Sanofi-Aventis Deutschland Gmbh Low pain penetrating member
US9226699B2 (en) 2002-04-19 2016-01-05 Sanofi-Aventis Deutschland Gmbh Body fluid sampling module with a continuous compression tissue interface surface
US9314194B2 (en) 2002-04-19 2016-04-19 Sanofi-Aventis Deutschland Gmbh Tissue penetration device
US9351680B2 (en) 2003-10-14 2016-05-31 Sanofi-Aventis Deutschland Gmbh Method and apparatus for a variable user interface
US9375169B2 (en) 2009-01-30 2016-06-28 Sanofi-Aventis Deutschland Gmbh Cam drive for managing disposable penetrating member actions with a single motor and motor and control system
US9386944B2 (en) 2008-04-11 2016-07-12 Sanofi-Aventis Deutschland Gmbh Method and apparatus for analyte detecting device
US9775553B2 (en) 2004-06-03 2017-10-03 Sanofi-Aventis Deutschland Gmbh Method and apparatus for a fluid sampling device

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US8641644B2 (en) 2000-11-21 2014-02-04 Sanofi-Aventis Deutschland Gmbh Blood testing apparatus having a rotatable cartridge with multiple lancing elements and testing means
US9795747B2 (en) 2010-06-02 2017-10-24 Sanofi-Aventis Deutschland Gmbh Methods and apparatus for lancet actuation
US9427532B2 (en) 2001-06-12 2016-08-30 Sanofi-Aventis Deutschland Gmbh Tissue penetration device
US9248267B2 (en) 2002-04-19 2016-02-02 Sanofi-Aventis Deustchland Gmbh Tissue penetration device
US7226461B2 (en) 2002-04-19 2007-06-05 Pelikan Technologies, Inc. Method and apparatus for a multi-use body fluid sampling device with sterility barrier release
US8702624B2 (en) 2006-09-29 2014-04-22 Sanofi-Aventis Deutschland Gmbh Analyte measurement device with a single shot actuator
US8784335B2 (en) 2002-04-19 2014-07-22 Sanofi-Aventis Deutschland Gmbh Body fluid sampling device with a capacitive sensor
US8574895B2 (en) 2002-12-30 2013-11-05 Sanofi-Aventis Deutschland Gmbh Method and apparatus using optical techniques to measure analyte levels
WO2005065414A2 (fr) 2003-12-31 2005-07-21 Pelikan Technologies, Inc. Procede et appareil permettant d'ameliorer le flux fluidique et le prelevement d'echantillons
WO2006011062A2 (fr) 2004-05-20 2006-02-02 Albatros Technologies Gmbh & Co. Kg Hydrogel imprimable pour biocapteurs
EP1765194A4 (fr) 2004-06-03 2010-09-29 Pelikan Technologies Inc Procede et appareil pour la fabrication d'un dispositif d'echantillonnage de liquides
EP2311374A1 (fr) * 2009-10-13 2011-04-20 Roche Diagnostics GmbH Appareil pour obtention et analyse du sang; mécanisme pour couplage d'une lancette
GB2522426A (en) * 2014-01-23 2015-07-29 Joanneum Res Forschungsgmbh Electrochemical and luminescent sensor structures integrated on common substrate
AU2015302025B2 (en) * 2014-08-11 2021-08-19 The Regents Of The University Of California Continuous analyte sensor

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Cited By (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8845550B2 (en) 2001-06-12 2014-09-30 Sanofi-Aventis Deutschland Gmbh Tissue penetration device
US9339612B2 (en) 2002-04-19 2016-05-17 Sanofi-Aventis Deutschland Gmbh Tissue penetration device
US8845549B2 (en) 2002-04-19 2014-09-30 Sanofi-Aventis Deutschland Gmbh Method for penetrating tissue
US8905945B2 (en) 2002-04-19 2014-12-09 Dominique M. Freeman Method and apparatus for penetrating tissue
US9226699B2 (en) 2002-04-19 2016-01-05 Sanofi-Aventis Deutschland Gmbh Body fluid sampling module with a continuous compression tissue interface surface
US9314194B2 (en) 2002-04-19 2016-04-19 Sanofi-Aventis Deutschland Gmbh Tissue penetration device
US8690796B2 (en) 2002-04-19 2014-04-08 Sanofi-Aventis Deutschland Gmbh Method and apparatus for penetrating tissue
US9144401B2 (en) 2003-06-11 2015-09-29 Sanofi-Aventis Deutschland Gmbh Low pain penetrating member
US8945910B2 (en) 2003-09-29 2015-02-03 Sanofi-Aventis Deutschland Gmbh Method and apparatus for an improved sample capture device
US9351680B2 (en) 2003-10-14 2016-05-31 Sanofi-Aventis Deutschland Gmbh Method and apparatus for a variable user interface
US9775553B2 (en) 2004-06-03 2017-10-03 Sanofi-Aventis Deutschland Gmbh Method and apparatus for a fluid sampling device
US9386944B2 (en) 2008-04-11 2016-07-12 Sanofi-Aventis Deutschland Gmbh Method and apparatus for analyte detecting device
US9375169B2 (en) 2009-01-30 2016-06-28 Sanofi-Aventis Deutschland Gmbh Cam drive for managing disposable penetrating member actions with a single motor and motor and control system
US8965476B2 (en) 2010-04-16 2015-02-24 Sanofi-Aventis Deutschland Gmbh Tissue penetration device

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AU2003300136A1 (en) 2004-07-29
AU2003300136A8 (en) 2004-07-29
EP1585978A2 (fr) 2005-10-19
WO2004060446A2 (fr) 2004-07-22
EP1585978A4 (fr) 2009-12-16

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