WO2004060338A1 - Preparation topique pour le soin de la peau et articles polymeres a base de caoutchouc elastomere trempe produits a partir de cette preparation - Google Patents

Preparation topique pour le soin de la peau et articles polymeres a base de caoutchouc elastomere trempe produits a partir de cette preparation Download PDF

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Publication number
WO2004060338A1
WO2004060338A1 PCT/AU2003/001351 AU0301351W WO2004060338A1 WO 2004060338 A1 WO2004060338 A1 WO 2004060338A1 AU 0301351 W AU0301351 W AU 0301351W WO 2004060338 A1 WO2004060338 A1 WO 2004060338A1
Authority
WO
WIPO (PCT)
Prior art keywords
tsf
rubber polymer
elastomeric rubber
dipped
polymer article
Prior art date
Application number
PCT/AU2003/001351
Other languages
English (en)
Inventor
Kwong Ann Lew
Leslie Martin Barclay
Ah Kiew Wong
Sarala Devi Jayaraman
Letchemy Muthu
Teck Yee Soh
Original Assignee
Wrp Asia Pacific Sdn. Bhd.
Ip Organisers Pty Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Wrp Asia Pacific Sdn. Bhd., Ip Organisers Pty Ltd filed Critical Wrp Asia Pacific Sdn. Bhd.
Priority to JP2004564085A priority Critical patent/JP2006516959A/ja
Priority to AU2003269587A priority patent/AU2003269587A1/en
Priority to EP03750151A priority patent/EP1583513A4/fr
Publication of WO2004060338A1 publication Critical patent/WO2004060338A1/fr

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L31/00Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
    • A61L31/14Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
    • A61L31/16Biologically active materials, e.g. therapeutic substances
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/02Cosmetics or similar toiletry preparations characterised by special physical form
    • A61K8/0204Specific forms not provided for by any of groups A61K8/0208 - A61K8/14
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/49Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds
    • A61K8/4986Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with sulfur as the only hetero atom
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/67Vitamins
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/96Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
    • A61K8/97Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
    • A61K8/9783Angiosperms [Magnoliophyta]
    • A61K8/9789Magnoliopsida [dicotyledons]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L31/00Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
    • A61L31/08Materials for coatings
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00Preparations for care of the skin
    • AHUMAN NECESSITIES
    • A41WEARING APPAREL
    • A41DOUTERWEAR; PROTECTIVE GARMENTS; ACCESSORIES
    • A41D19/00Gloves
    • A41D19/0055Plastic or rubber gloves
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2800/00Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
    • A61K2800/74Biological properties of particular ingredients
    • A61K2800/75Anti-irritant
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/20Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices containing or releasing organic materials
    • A61L2300/30Compounds of undetermined constitution extracted from natural sources, e.g. Aloe Vera
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/40Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a specific therapeutic activity or mode of action
    • A61L2300/428Vitamins, e.g. tocopherol, riboflavin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/40Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a specific therapeutic activity or mode of action
    • A61L2300/452Lubricants

Definitions

  • the present invention relates to a Topical Skin-Care Formulation (TSF) and dipped elastomeric rubber polymer articles produced utilising the TSF. More particularly, the present invention relates to the TSF and dipped elastomeric rubber polymer gloves produced utilising the TSF.
  • TSF Topical Skin-Care Formulation
  • Aloe Vera using a solution from prepared Aloe Vera, applied to the inner surface of natural rubber and nitrile rubber gloves has been described in US Patent 6,274,154. Aloe Vera has been part of folk medicine and is best known for its healing ability for scalds, scrapes and burns (from heat or radiation).
  • the majority of gloves used are the low cost disposable medical examination gloves and ideally, the additives used to improve comfort and hygiene for the wearer, must be economically realistic. In other words, they must be low cost materials, or be effective at very low levels, so that the skin-care coated glove can be marketed at viable prices.
  • any applied coating does not have any significant adverse effect on the integrity of the glove.
  • the coating must not cause increase in pin-hole levels or have any significant effect on the physical properties of the glove, either before or after prolonged storage. Additionally, the coating material should not have any tendency to bacterial or fungal attack itself, which can occur with some types of plant extracts and this could then lead to infection of gloves during storage.
  • TSF Topical Skin-Care Formulation
  • TSF including effective amounts of Vitamins A, B and E, ⁇ -lipoic acid,
  • a dipped elastomeric rubber polymer article such as a glove or a condom to protect and soothe the human's skin which is in contact with the said surface of the dipped elastomeric rubber polymer article.
  • a dipped elastomeric rubber polymer article such as a glove or a condom
  • the said dipped elastomeric rubber polymer article is provided with a layer of Topical Skin-Care Formulation (TSF), said TSF
  • Vitamins A, B and E including effective amounts of Vitamins A, B and E, ⁇ -lipoic acid, eucalyptus,
  • a method of manufacturing a Topical Skin-Care Formulation (TSF) coated dipped elastomeric rubber polymer article such as a glove or a condom, comprising the steps of preparing the TSF, the said TSF including
  • Vitamins A, B and E effective amounts of Vitamins A, B and E, ⁇ -lipoic acid, eucalyptus, jojoba and
  • said carrier enables the TSF to be applied on a surface of an elastomeric rubber polymer article either by dipping the elastomeric rubber polymer article into the TSF during the final stages of the dipped elastomeric rubber polymer article manufacture or by an off-line coating application process so that the surface of the elastomeric rubber polymer article is in contact with the TSF, transferring the dipped TSF coated elastomeric rubber polymer article to a drying process which causes water in the portion of the TSF to evaporate and form a substantially evenly distributed layer of TSF on the surface of the dipped TSF coated elastomeric rubber polymer article and cooling the dipped
  • TSF coated elastomeric rubber polymer article to room temperature.
  • TSF Topical Skin-Care Formulation
  • a dipped elastomeric rubber polymer article such as a glove or a condom.
  • the present invention relates to a Topical Skin-Care Formulation (TSF) and dipped elastomeric rubber polymer articles produced from the TSF. More particularly, the present invention relates to the TSF and dipped elastomeric rubber polymer gloves produced incorporating the TSF.
  • TSF Topical Skin-Care Formulation
  • TSF Topical Skin- Care Formulation
  • Vitamins A, B and E and the ⁇ -lipoic acid are known for their anti-oxidant
  • the eucalyptus is a well-known antiseptic in many preparations and also gives a cooling effect whilst jojoba imparts moisturising and a soothing effect.
  • the coating can be applied to powdered disposable gloves.
  • the coating material is released from the inner surface of the glove to the contacting skin of the wearer's hand via moisture from the hand.
  • the wearer can feel a soothing sensation and also, the TSF can release its moisturising, protective and antiseptic properties.
  • the present invention also provides a use of a carrier to enable the TSF.
  • the carrier is necessary to ensure homogeneity of all the components of the TSF to provide uniform distribution of the components when coated onto a dipped elastomeric rubber polymer articles such as gloves and condoms.
  • An emollient cream is selected as a carrier for the components of the TSF and also as a moisturising cream to provide more comfort and softness for the skin.
  • Gloves are manufactured by conventional processes to produce "powdered” gloves. These gloves, which may be made from natural rubber, nitrile rubber, polyisoprene rubber, polychloroprene rubber, or any blend of these rubbers, would be subjected to a process of chlorination. This process is normally carried out off-line in specially designed machines and during the process, the powder is removed from the gloves and the chlorine reacts with the rubber surfaces.
  • the process may be that of a single chlorination cycle or that of two chlorination cycles, in which the gloves are inverted after the first chlorination cycle. In the single chlorination process it is usual for the gloves to have the donning surface on the outside of the gloves and only at a later stage, are the gloves inverted, either before or after final drying.
  • the chlorinated gloves are subjected to a number of water rinsing cycles to remove unwanted chemicals from the gloves.
  • the water-based dispersion of the TSF may then be included in the final rinse cycle, by adding the correct concentration of the TSF to the water and allowing the gloves to be thoroughly and uniformly coated with the TSF.
  • Gloves may be coated by an on-line dipping process, in which the gloves will be dipped into an aqueous dispersion of the TSF after completing all post-cure
  • the gloves would then be dried on-line at temperatures up to 120°C,
  • gloves it would be normal to use a powder- free coagulant system, so that the gloves will not require any off-line processing, other than drying.
  • Such gloves can be coated with polymer by an on-line process or be subjected to an on-line chlorination process and dried, prior to dipping in the aqueous dispersion of the TSF. After dipping in the TSF, the gloves would pass through a drying oven at a temperature in the range 80 -
  • Gloves may also be coated with the TSF on-line, by dipping into aqueous polymer dispersion, containing the TSF, followed by similar processing steps as in EXAMPLE 2.
  • Gloves may be coated with the TSF on-line, by dipping into a tank containing an aqueous dispersion of the TSF after the final rinse process of an on-line chlorination process.
  • the gloves would not be dried prior to dipping in the TSF dispersion. After emerging from the TSF dispersion, the gloves would pass through a drying oven at a temperature in the range 80 - 120 9 C, cooled and finally stripped.
  • Gloves may be coated by spraying a fine mist of aqueous dispersion of the TSF on to gloves in a tumbler drier. If the gloves are inverted during this process, then the donning surface will be on the outside and will become coated with the
  • the temperature in the drier may be in the range 50 to 90°C. This method
  • Powdered gloves may be produced, which also have a coating of the TSF.
  • the coating of the TSF may be applied by incorporating the TSF dispersion in the final wet-powder slurry, so that the donning surface will be coated with powder and the TSF, at the same time.
  • any of the above methods can produce gloves having a uniform coating of the TSF on the donning surface of the rubber gloves, which are essentially a uniform residual coating on the surface of the gloves, after the water in the dispersion has evaporated during drying processes.
  • some of the TSF will be released from surface of the glove and will contact the skin of the wearer's hands, imparting a soothing effect and a degree of protection against bacteria and skin irritants.
  • Extensive testing of gloves coated with the TSF has shown that the material has no measurable adverse effect on the integrity of gloves, made from natural rubber, nitrile rubber, polychloroprene rubber, polyisoprene rubber, or any blend of these rubbers.
  • Various types of gloves and processes which can utilise the benefits of coating glove inner surfaces with the TSF has been described herein before. This does not necessarily include all methods of manufacturing coated gloves and there are likely to be other individual manufacturing techniques in this widespread glove industry.

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Epidemiology (AREA)
  • Birds (AREA)
  • Engineering & Computer Science (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Vascular Medicine (AREA)
  • Surgery (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Botany (AREA)
  • Mycology (AREA)
  • Chemical & Material Sciences (AREA)
  • Biomedical Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Dermatology (AREA)
  • Gloves (AREA)
  • Orthopedics, Nursing, And Contraception (AREA)
  • Cosmetics (AREA)

Abstract

La présente invention concerne une préparation topique pour le soin de la peau contenant des doses utiles de vitamine A, B et E, de l'acide alpha-lipoïque, de l'eucalyptus, du jojoba et un substrat, tel qu'une crème émolliente. L'invention concerne également un article polymère à base de caoutchouc élastomère trempé produit à partir de ladite préparation topique, son procédé de fabrication et l'utilisation d'un substrat permettant l'application de ladite préparation topique sur la surface d'un article polymère à base de caoutchouc élastomère trempé. L'enduit utilisé pour les articles polymères à base de caoutchouc élastomère trempé, tels que des gants en caoutchouc ou des préservatifs, offre une plus grande protection à l'utilisateur, possède des propriétés hydratantes, protectrices et antiseptiques, et fournit un plus grand confort grâce à des effets apaisants et rafraîchissants. L'invention concerne également des articles polymères à base de caoutchouc élastomère trempé non stériles, enduits à l'aide desdits ingrédients, présentant une plus faible concentration de bactéries que d'autres articles polymères similaires. L'enduit utilisé n'affecte en rien les propriétés physiques des articles polymères à base de caoutchouc élastomère trempé.
PCT/AU2003/001351 2003-01-03 2003-10-13 Preparation topique pour le soin de la peau et articles polymeres a base de caoutchouc elastomere trempe produits a partir de cette preparation WO2004060338A1 (fr)

Priority Applications (3)

Application Number Priority Date Filing Date Title
JP2004564085A JP2006516959A (ja) 2003-01-03 2003-10-13 部分用スキンケア・フォーミュレーション及び部分用スキンケア・フォーミュレーションを利用して製造された浸漬エラストマー・ゴム・ポリマー製品
AU2003269587A AU2003269587A1 (en) 2003-01-03 2003-10-13 A topical skin-care formuation (tsf) and dipped elastomeric rubber polymer articles produced utilising the tsf
EP03750151A EP1583513A4 (fr) 2003-01-03 2003-10-13 Preparation topique pour le soin de la peau et articles polymeres a base de caoutchouc elastomere trempe produits a partir de cette preparation

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
MYPI20030019 2003-01-03
MYPI20030019 2003-01-03

Publications (1)

Publication Number Publication Date
WO2004060338A1 true WO2004060338A1 (fr) 2004-07-22

Family

ID=32709950

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/AU2003/001351 WO2004060338A1 (fr) 2003-01-03 2003-10-13 Preparation topique pour le soin de la peau et articles polymeres a base de caoutchouc elastomere trempe produits a partir de cette preparation

Country Status (4)

Country Link
EP (1) EP1583513A4 (fr)
JP (1) JP2006516959A (fr)
AU (1) AU2003269587A1 (fr)
WO (1) WO2004060338A1 (fr)

Cited By (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2005033229A1 (fr) * 2003-10-07 2005-04-14 Wrp Asia Pacific Sdn. Bhd. Couche d'impression intermediaire
NL1031084C2 (nl) * 2006-02-06 2007-08-07 Bob Hoogenboom Huidverzorgingsproduct.
WO2009021299A1 (fr) * 2007-08-10 2009-02-19 Balbino Leticia Gomes Tavares Gants, bottes et pantoufles en plastique revêtus d'un émollient et d'une préparation désinfectante, à usage professionnel des manucures et pédicures, et dispensant l'utilisation d'eau, grâce à l'hydratation de la peau, des ongles et des cuticules par occlusion
JP2010214210A (ja) * 2004-08-27 2010-09-30 Coloplast As 泌尿器外部カテーテル
US7971276B2 (en) 2005-12-01 2011-07-05 Ansell Healthcare Products, Llc Glove with hand-friendly coating and method of making
WO2014198366A1 (fr) * 2013-06-14 2014-12-18 Carl Freudenberg Kg Gant a effet rafraichissant
WO2018119491A1 (fr) * 2016-12-30 2018-07-05 Skinprotect Corporation Sdn Bhd Articles élastomères présentant des propriétés de soin de la peau et leurs procédés de production

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6274154B1 (en) * 1999-04-07 2001-08-14 Belle L Chou Aloe Vera glove and manufacturing method

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2001008541A1 (fr) * 1999-08-02 2001-02-08 Okeeffe Paul John Article manufacture et methode d'application d'un gant de protection

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6274154B1 (en) * 1999-04-07 2001-08-14 Belle L Chou Aloe Vera glove and manufacturing method

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
See also references of EP1583513A4 *

Cited By (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2005033229A1 (fr) * 2003-10-07 2005-04-14 Wrp Asia Pacific Sdn. Bhd. Couche d'impression intermediaire
JP2010214210A (ja) * 2004-08-27 2010-09-30 Coloplast As 泌尿器外部カテーテル
US7971276B2 (en) 2005-12-01 2011-07-05 Ansell Healthcare Products, Llc Glove with hand-friendly coating and method of making
NL1031084C2 (nl) * 2006-02-06 2007-08-07 Bob Hoogenboom Huidverzorgingsproduct.
EP1837055A1 (fr) * 2006-02-06 2007-09-26 Bob Hoogenboom Crème de soin dermatologique
WO2009021299A1 (fr) * 2007-08-10 2009-02-19 Balbino Leticia Gomes Tavares Gants, bottes et pantoufles en plastique revêtus d'un émollient et d'une préparation désinfectante, à usage professionnel des manucures et pédicures, et dispensant l'utilisation d'eau, grâce à l'hydratation de la peau, des ongles et des cuticules par occlusion
WO2014198366A1 (fr) * 2013-06-14 2014-12-18 Carl Freudenberg Kg Gant a effet rafraichissant
WO2018119491A1 (fr) * 2016-12-30 2018-07-05 Skinprotect Corporation Sdn Bhd Articles élastomères présentant des propriétés de soin de la peau et leurs procédés de production
US11207250B2 (en) 2016-12-30 2021-12-28 Skinprotect Corporation Sdn Bhd Elastomeric articles having skin care properties and methods for their production
US11896690B2 (en) 2016-12-30 2024-02-13 Skinprotect Corporation Sdn Bhd Elastomeric articles having skin care properties and methods for their production

Also Published As

Publication number Publication date
EP1583513A4 (fr) 2006-11-29
AU2003269587A1 (en) 2004-07-29
JP2006516959A (ja) 2006-07-13
EP1583513A1 (fr) 2005-10-12

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