WO2004055158A3 - Therapeutic polypeptides, nucleic acids encoding same, and methods of use - Google Patents

Therapeutic polypeptides, nucleic acids encoding same, and methods of use Download PDF

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Publication number
WO2004055158A3
WO2004055158A3 PCT/US2003/031817 US0331817W WO2004055158A3 WO 2004055158 A3 WO2004055158 A3 WO 2004055158A3 US 0331817 W US0331817 W US 0331817W WO 2004055158 A3 WO2004055158 A3 WO 2004055158A3
Authority
WO
WIPO (PCT)
Prior art keywords
methods
novel
nucleic acids
polypeptide
polypeptides
Prior art date
Application number
PCT/US2003/031817
Other languages
French (fr)
Other versions
WO2004055158A2 (en
Inventor
David Anderson
Edward Voss
Nikolai Khramtsov
Xiaojia Sasha Guo
Daniel Rieger
Li Li
Glennda Smithson
Ramesh Kekuda
Peter Mezes
Original Assignee
Curagen Corp
David Anderson
Edward Voss
Nikolai Khramtsov
Xiaojia Sasha Guo
Daniel Rieger
Li Li
Glennda Smithson
Ramesh Kekuda
Peter Mezes
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Curagen Corp, David Anderson, Edward Voss, Nikolai Khramtsov, Xiaojia Sasha Guo, Daniel Rieger, Li Li, Glennda Smithson, Ramesh Kekuda, Peter Mezes filed Critical Curagen Corp
Priority to AU2003282764A priority Critical patent/AU2003282764A1/en
Publication of WO2004055158A2 publication Critical patent/WO2004055158A2/en
Publication of WO2004055158A3 publication Critical patent/WO2004055158A3/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Zoology (AREA)
  • Medicinal Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Wood Science & Technology (AREA)
  • Molecular Biology (AREA)
  • Engineering & Computer Science (AREA)
  • Toxicology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biophysics (AREA)
  • Biomedical Technology (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • General Engineering & Computer Science (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)

Abstract

Disclosed herein are novel nucleic acid sequences that encode novel polypeptides. Also disclosed are polypeptides encoded by these nucleic acid sequences, and antibodies that immunospecifically bind to the polypeptide, as well as derivatives, variants mutants, or fragments of the novel polypeptide, polynucleotide, or antibody specific to the polypeptide. Vectors host cells, antibodies and recombinant methods for producing the polypeptides and polynucleotides, as well as methods for using same are also included. The invention further discloses therapeutic, diagnostic and research methods for diagnosis, treatment, and prevention of disorders involving any one of these novel human nucleic acids and proteins.
PCT/US2003/031817 2001-10-05 2003-10-07 Therapeutic polypeptides, nucleic acids encoding same, and methods of use WO2004055158A2 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
AU2003282764A AU2003282764A1 (en) 2002-10-07 2003-10-07 Therapeutic polypeptides, nucleic acids encoding same, and methods of use

Applications Claiming Priority (13)

Application Number Priority Date Filing Date Title
US09/972211 2001-10-05
US41666202P 2002-10-07 2002-10-07
US60/416,662 2002-10-07
US41880802P 2002-10-16 2002-10-16
US60/418,808 2002-10-16
US42096802P 2002-10-24 2002-10-24
US60/420,968 2002-10-24
US42115502P 2002-10-25 2002-10-25
US60/421,155 2002-10-25
US42169802P 2002-10-28 2002-10-28
US60/421,698 2002-10-28
US42379502P 2002-11-05 2002-11-05
US60/423,795 2002-11-05

Publications (2)

Publication Number Publication Date
WO2004055158A2 WO2004055158A2 (en) 2004-07-01
WO2004055158A3 true WO2004055158A3 (en) 2005-08-04

Family

ID=32601216

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2003/031817 WO2004055158A2 (en) 2001-10-05 2003-10-07 Therapeutic polypeptides, nucleic acids encoding same, and methods of use

Country Status (2)

Country Link
AU (1) AU2003282764A1 (en)
WO (1) WO2004055158A2 (en)

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2002050258A1 (en) * 2000-12-18 2002-06-27 Yamanouchi Pharmaceutical Co., Ltd. Novel aggrecanase
JP2003144154A (en) * 2001-11-14 2003-05-20 Mitsubishi Pharma Corp New adamts family polypeptide and gene encoding the same
WO2003064622A2 (en) * 2002-01-31 2003-08-07 Wyeth Aggrecanase molecules

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2002050258A1 (en) * 2000-12-18 2002-06-27 Yamanouchi Pharmaceutical Co., Ltd. Novel aggrecanase
JP2003144154A (en) * 2001-11-14 2003-05-20 Mitsubishi Pharma Corp New adamts family polypeptide and gene encoding the same
WO2003064622A2 (en) * 2002-01-31 2003-08-07 Wyeth Aggrecanase molecules

Also Published As

Publication number Publication date
AU2003282764A1 (en) 2004-07-09
AU2003282764A8 (en) 2004-07-09
WO2004055158A2 (en) 2004-07-01

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