WO2004052734A1 - Squeeze-bottle of liquid medicine - Google Patents
Squeeze-bottle of liquid medicine Download PDFInfo
- Publication number
- WO2004052734A1 WO2004052734A1 PCT/GB2003/005314 GB0305314W WO2004052734A1 WO 2004052734 A1 WO2004052734 A1 WO 2004052734A1 GB 0305314 W GB0305314 W GB 0305314W WO 2004052734 A1 WO2004052734 A1 WO 2004052734A1
- Authority
- WO
- WIPO (PCT)
- Prior art keywords
- bottle
- liquid medicine
- neck
- rear panels
- waist
- Prior art date
Links
Classifications
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B65—CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
- B65D—CONTAINERS FOR STORAGE OR TRANSPORT OF ARTICLES OR MATERIALS, e.g. BAGS, BARRELS, BOTTLES, BOXES, CANS, CARTONS, CRATES, DRUMS, JARS, TANKS, HOPPERS, FORWARDING CONTAINERS; ACCESSORIES, CLOSURES, OR FITTINGS THEREFOR; PACKAGING ELEMENTS; PACKAGES
- B65D1/00—Containers having bodies formed in one piece, e.g. by casting metallic material, by moulding plastics, by blowing vitreous material, by throwing ceramic material, by moulding pulped fibrous material, by deep-drawing operations performed on sheet material
- B65D1/32—Containers adapted to be temporarily deformed by external pressure to expel contents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
- A61J1/00—Containers specially adapted for medical or pharmaceutical purposes
- A61J1/05—Containers specially adapted for medical or pharmaceutical purposes for collecting, storing or administering blood, plasma or medical fluids ; Infusion or perfusion containers
- A61J1/06—Ampoules or carpules
- A61J1/067—Flexible ampoules, the contents of which are expelled by squeezing
Definitions
- the present invention relates to a bottle for liquid medicine .
- bottles for liquid medicine have an open neck, and the medicine is dispensed by pouring.
- the bottle is not adapted to be squeezed to impel the medicine from the bottle. Rather, it flows under gravity, into a measuring spoon or the like. When the measuring spoon is full to the required mark the bottle is placed upright again, and the cap put on sealingly to cover the neck.
- a medicine bottle which overcomes or eases at least one of the problems mentioned above.
- a bottle containing liquid medicine the bottle having a neck containing a self-sealing closure, the bottle being flexible such that, when it is inverted or tilted downwardly, squeezing the bottle produces a flow of liquid medicine through the closure, and releasing the bottle terminates the flow of liquid medicine.
- inverted , or tilted downwardly we mean that the bottle is oriented with the neck as the lowest part of the bottle.
- the bottle has visually distinct upper and lower regions and a waist at the junction between them.
- the upper region has rounded, downwardly sloping shoulders extending between the waist and the neck of the bottle.
- each shoulder is substantially an arc of a circle.
- the arc is 40-80°, preferably 50-70°, of a circle whose centre is adjacent to the waist at the bottom of the opposite shoulder, but within the extent of the bottle.
- the lower region of the bottle tapers from the base of the bottle to the waist.
- the lower region is taller than the upper region. More preferably the waist is located between 25% and 45%, most preferably between 35 and 42%, of the distance from the bottom of the neck of the bottle to the base of the bottle .
- the height of the lower region is between 4 and 10 cm, preferably between 5 and 7 cm.
- the height of the upper region is between 3 and 5 cm.
- the height of the bottle, up to the base of the neck is between 7 and 15 cm, preferably between 8 and 12 cm.
- the external walls of the bottle represent the boundaries for the liquid medicine; preferably there is no bottle liner.
- the volume of the bottle, up to the base of the neck is between 50 and 250 ml, more preferably between 80 and 200 ml, most preferably between 100 and 160 ml.
- the bottle has front and rear panels.
- each is movable toward the other. These may be connected directly to each other - preferably such that the bottle is generally oval in cross-section - or may be connected together by means of side walls.
- the bottle is generally of box form, having larger front and rear panels connected to each other by two narrower side walls.
- the front and rear panels are preferably each somewhat outwardly bowed so that they may be moved into a flatter form, one toward the other, to impel medicine from the bottle .
- the bottle is designed such that the front and rear panels may be moved smoothly from their rest position to their fully inward position.
- the wall material of the bottle does not kink or crease abruptly as the panels are moved to their fully inward position.
- the bottle is designed such that there is, a limit to the inward movement of the front and rear panels in normal use, the limit position preferably being, under a moderate squeezing force adequate to provide the flow of liquid, the limit of flexure rather than the onset of kinking, creasing, or the like.
- the volume of the bottle in this limit position of the front and rear panels is at least 80% of the volume of the bottle.
- front and rear panels which, in elevation, show the outline of any shaping of the bottle - for example when the upper region has shoulders and/or the lower region tapers.
- side walls which preferably have these features in relief.
- the maximum width of the front and rear panels is at least twice the maximum width of the side walls (when provided) .
- the bottle When the bottle has side walls it is designed such that the bottle cannot be pressed by force applied across the side walls to any useful degree, i.e. without the wall material kinking or creasing.
- the bottle is made of a plastics material of such a type, and formed with such a thickness, that it may be elastically flexed in order to reduce the volume of the container, and impel liquid medicine inside it.
- a suitable material is a polyester, for example polyethylene terephthalate (PET) .
- PET polyethylene terephthalate
- the bottle material is transparent, but is UV-resistant and/or coloured, preferably being brown.
- the bottle may be formed by a regular bottle-forming process in which a body of plastics material is heated and blown into a mould cavity.
- the neck of the bottle preferably has press-fitted into it, in a sealing manner, a valve module, containing the self-sealing closure.
- the self-sealing closure preferably has a fitment piece, for securement in the neck, and a valve.
- the fitment piece preferably includes an annulus of supporting material, preferably a rigid plastics material, which has, depending orthogonally from it, a cylindrical piece which fits grippingly within the neck of the bottle, and, extending laterally outside that, a flange which rests against the rim of the neck.
- the valve is preferably a slit valve of a plastics material, for example of an elasto eric or polyolefin material .
- the plastics material is an elastomeric material, most preferably a silicone elastomeric material.
- the valve is urged open by raised pressure inside the bottle, and automatically seals over once again, when the pressure is released. Examples of such valves may be seen in US 5954237, US 5439143 and US 6446844.
- a preferred valve has contacting surfaces which are spread apart to allow the liquid to pass.
- the valve does not comprise a flap, for example a hinged or cantilevered flap.
- the external surface of the neck may be formed with a screw thread, onto which a cap may be screwed.
- the cap is preferably of a child-proof type.
- the cap is of a tamper-evident type.
- the medicine is a viscous liquid, most preferably a syrup.
- a preferred embodiment of the invention is a bottle containing liquid medicine, the bottle having a self- sealing closure in its neck; the bottle being flexible such that when it is inverted, squeezing the bottle produces a flow of liquid medicine through the closure, and releasing the bottle terminates the flow of liquid medicine, preferably with the bottle reverting to its original shape; the bottle preferably being shaped so as to assist this operation, in particular in preferably having major front and rear panels, which can be controllably flexed.
- a method of dispensing liquid medicine using a liquid medicine- containing bottle of the first aspect.
- a bottle containing liquid medicine has its cap removed and is turned so that the neck is lowermost.
- a measuring spoon or cup is held beneath the neck and the bottle gently squeezed, whereupon a smooth stream of liquid medicine is impelled into the spoon or cup.
- the user releases the squeezing force and the stream of medicine is immediately terminated, without dripping.
- the bottle is placed upright once again and the cap replaced.
- the bottle has been designed to promote easy and accurate operation.
- the preferred features of the taper in the lower region and the shoulders of the upper region, with the waist between them, are such that users are encouraged to hold the front and rear panels of the bottle.
- they may grasp the lower region of the bottle, either with their finger wrapped around the lower region, with their forefinger around the waist, or with fingertips against one of the panels and thumb against the other of the panels. In either position the natural action is to gently press the ront panel and/or the rear panel .
- Fig. 1 is a frontal view of a bottle of the invention with its cap off;
- Fig. 2 is a side view of the same bottle with its cap on;
- Fig. 3 is a plan view of the same bottle with its cap off, from above; and Fig. 4 is an under-plan view of the same bottle, from below.
- the bottle shown in the drawings contains a viscous liquid medicine, such as a cough syrup.
- the bottle may generally be described as being of box-form, having front and rear panels 2, 4, identical with each other, and two side panels indicated generally as 6, 8, identical with each other.
- the width of the side panels is considerably less than the width of the front and rear panels, by a ratio of approximately 1:3.
- the bottle may be viewed as having a box-like structure, as distinct from a traditional bottle shape of a cylinder surmounted by a frusto-conical top region, it is not of cuboid shape.
- a box-like structure as distinct from a traditional bottle shape of a cylinder surmounted by a frusto-conical top region, it is not of cuboid shape.
- important shape features which will now be described.
- the bottle has a lower region 10, and an upper region 12.
- the bottle's neck 14 projects upwards from the top of the upper region.
- the lower region tapers in the upward direction.
- the side panels 6, 8 are somewhat inwardly directed, in the lower region.
- the upper region has two outwardly projecting formations, in the form of shoulders 15, 16.
- the shoulders are rounded and downwardly sloping, and extend between the neck of the bottle and the junction between the upper region and the lower region. It may be seen that at this junction the bottle has a waist 18.
- Each shoulder can be seen as representing an approximately 60° arc of a circle whose centre is near to the opposite shoulder, adjacent to the waist 18.
- shoulders 15, 16 are formed as relief features in the side panels 6, 8, and this can best be seen in Fig. 2.
- each shoulder 15, 16 and the respective tapering region 6, 8 is of curved, upwardly-facing form.
- the front and rear panels 2, 4 and the side panels 6, 8 terminate at the bottom of the bottle in a base wall 20, shown in Fig. 4. From this it may be seen that the front and rear panels 2, 4 are markedly convex.
- the side walls 6, 8 are very slightly convex. Due to their convex shape portions of the side walls may be seen in Fig. 2, and are indicated as 2A, 4A.
- a self-sealing closure 24 Fitted into the neck 14 of the bottle is a self-sealing closure 24, seen in Fig. 4.
- the closure consists of an annular plastics body 26 resting on the rim of the neck. It has as cylindrical part (not shown) resiliently retained within the neck.
- the plastics body supports in the opening within it a cross-slit silicone valve 28.
- the valve 28 is of the type which remains closed in all orientations until the liquid medicine is in some manner impelled. When the impelling force is removed the closure seals once again.
- the bottle wall is of a brown transparent flexible plastics (PET) material. Its volume may be reduced by squeezing, in order to impel liquid medicine through the closure 24. Because of the design of the bottle the side panels 6, 8 feel comparatively rigid whereas the front and rear panels 2, 4 feel much more flexible, in the upper region 12 and, especially, in the lower region 10.
- the bottle is designed such that the front and rear panels may be moved smoothly towards each other but with immediate relaxation when the force is removed. Applying a similar force to the side panels yields no such action. Rather, the force is initially resisted, then, if a substantial force is applied to the side walls, they abruptly crumple or collapse inwardly.
- the neck of the bottle is formed with a screw thread 30 and the cap 32 has a corresponding internal screw thread.
- the distance between the top of the upper region 12 (ie the base of the neck 14) to the waist 18 is approximately four-tenths of the distance between the top of the upper region 12 to the base wall 20.
- the width of the base wall is about 5.3 cm.
- the width of the waist is about 4.7 cm.
- the maximum width of the upper region is about 5.0 cm.
- the distance between the top of the upper region and the waist s about 4.0 cm and the distance between the top of the upper region and the base wall is about 10.0 cm.
- the volume of the bottle (not including the neck space) is about 140 ml and is intended to supply about 125 ml of liquid medicine.
- the cap is removed, the bottle is inverted or downwardly tilted (as the user prefers) , and the front and/or rear panel pressed in order to dispense liquid medicine into a measuring device, for example a measuring cup or spoon.
- the bottle is designed so that the user is encouraged to press the front and/or rear panel 2, 4 in order to impel the liquid medicine through the closure 24.
- it is designed so that it fits comfortably within the hand, with the fingers of the user around the lower region, with the forefinger resting under one of the shoulders 14, 16, that is, around the waist 18; or with fingertips on one panel and thumb on the other.
Abstract
Description
Claims
Priority Applications (5)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CA002506437A CA2506437A1 (en) | 2002-12-06 | 2003-12-05 | Squeeze-bottle of liquid medicine |
AU2003288431A AU2003288431A1 (en) | 2002-12-06 | 2003-12-05 | Squeeze-bottle of liquid medicine |
US10/532,126 US20060016835A1 (en) | 2002-12-06 | 2003-12-05 | Squeeze-bottle of liquid medicine |
NZ539391A NZ539391A (en) | 2002-12-06 | 2003-12-05 | Squeeze-bottle of liquid medicine with self-sealing closure |
EP03780350A EP1567419A1 (en) | 2002-12-06 | 2003-12-05 | Squeeze-bottle of liquid medicine |
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB0228483.4 | 2002-12-06 | ||
GBGB0228483.4A GB0228483D0 (en) | 2002-12-06 | 2002-12-06 | Bottle |
Publications (1)
Publication Number | Publication Date |
---|---|
WO2004052734A1 true WO2004052734A1 (en) | 2004-06-24 |
Family
ID=9949193
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PCT/GB2003/005314 WO2004052734A1 (en) | 2002-12-06 | 2003-12-05 | Squeeze-bottle of liquid medicine |
Country Status (10)
Country | Link |
---|---|
US (1) | US20060016835A1 (en) |
EP (1) | EP1567419A1 (en) |
AU (1) | AU2003288431A1 (en) |
CA (1) | CA2506437A1 (en) |
GB (1) | GB0228483D0 (en) |
NZ (1) | NZ539391A (en) |
PL (1) | PL375571A1 (en) |
RU (1) | RU2005121273A (en) |
WO (1) | WO2004052734A1 (en) |
ZA (1) | ZA200502974B (en) |
Families Citing this family (29)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB2414402B (en) * | 2004-05-28 | 2009-04-22 | Cilag Ag Int | Injection device |
GB2414775B (en) | 2004-05-28 | 2008-05-21 | Cilag Ag Int | Releasable coupling and injection device |
GB2414400B (en) * | 2004-05-28 | 2009-01-14 | Cilag Ag Int | Injection device |
GB2425062B (en) | 2005-04-06 | 2010-07-21 | Cilag Ag Int | Injection device |
GB2427826B (en) | 2005-04-06 | 2010-08-25 | Cilag Ag Int | Injection device comprising a locking mechanism associated with integrally formed biasing means |
GB2424836B (en) * | 2005-04-06 | 2010-09-22 | Cilag Ag Int | Injection device (bayonet cap removal) |
PT1759729E (en) | 2005-08-30 | 2010-03-04 | Cilag Gmbh Int | Needle assembly for a prefilled syringe system |
US20110098656A1 (en) * | 2005-09-27 | 2011-04-28 | Burnell Rosie L | Auto-injection device with needle protecting cap having outer and inner sleeves |
GB2438593B (en) | 2006-06-01 | 2011-03-30 | Cilag Gmbh Int | Injection device (cap removal feature) |
GB2438590B (en) * | 2006-06-01 | 2011-02-09 | Cilag Gmbh Int | Injection device |
GB2438591B (en) * | 2006-06-01 | 2011-07-13 | Cilag Gmbh Int | Injection device |
CA2682888A1 (en) * | 2007-04-06 | 2008-10-16 | Transform Pharmaceuticals, Inc. | Systems and methods for delivering a fluid drug |
GB2461086B (en) * | 2008-06-19 | 2012-12-05 | Cilag Gmbh Int | Injection device |
GB2461087B (en) * | 2008-06-19 | 2012-09-26 | Cilag Gmbh Int | Injection device |
GB2461089B (en) * | 2008-06-19 | 2012-09-19 | Cilag Gmbh Int | Injection device |
GB2461088B (en) * | 2008-06-19 | 2012-09-26 | Cilag Gmbh Int | Injection device |
GB2461084B (en) * | 2008-06-19 | 2012-09-26 | Cilag Gmbh Int | Fluid transfer assembly |
GB2461085B (en) * | 2008-06-19 | 2012-08-29 | Cilag Gmbh Int | Injection device |
US20130184527A1 (en) * | 2008-08-12 | 2013-07-18 | Omnimed Enterprises, LLC | Medical Instrument Light Source Connection Device |
US9694944B2 (en) * | 2012-03-06 | 2017-07-04 | Prince Castle LLC | Dispenser for viscous food products |
GB2515038A (en) | 2013-06-11 | 2014-12-17 | Cilag Gmbh Int | Injection device |
GB2515032A (en) | 2013-06-11 | 2014-12-17 | Cilag Gmbh Int | Guide for an injection device |
GB2517896B (en) | 2013-06-11 | 2015-07-08 | Cilag Gmbh Int | Injection device |
GB2515039B (en) | 2013-06-11 | 2015-05-27 | Cilag Gmbh Int | Injection Device |
SE542713C2 (en) * | 2016-08-23 | 2020-06-30 | Winnington Ab | Product container comprising transparent member |
WO2019152954A1 (en) * | 2018-02-05 | 2019-08-08 | Parks Richard Lynn | Mixer for a sports and water bottle |
US10479543B1 (en) * | 2018-05-09 | 2019-11-19 | Robert William Bowling | Container for storing, dispensing, and serving liquids |
JP7154691B2 (en) * | 2018-06-29 | 2022-10-18 | 株式会社吉野工業所 | squeeze container |
USD1013521S1 (en) | 2021-04-08 | 2024-02-06 | H.J. Heinz Company Brands Llc | Bottle |
Citations (9)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3572590A (en) * | 1968-05-31 | 1971-03-30 | Afa Corp | Squeeze bottle atomizers and liquid dispensers |
DE7923294U1 (en) * | 1979-08-16 | 1980-01-03 | Pfaelzische Sprit Und Chem Fab | Dosing container |
GB2106480A (en) * | 1981-09-29 | 1983-04-13 | Shinko Chem | Valve and container for medical liquids |
US5439143A (en) | 1991-12-06 | 1995-08-08 | Liquid Molding Systems, Inc. | Dispensing valve for packaging |
US5954237A (en) | 1995-08-25 | 1999-09-21 | The Coca-Cola Company | Dispensing valve closure with inner seal |
GB2339757A (en) * | 1998-07-17 | 2000-02-09 | Unilever Plc | Dispensing containers |
DE10112741A1 (en) * | 2000-03-09 | 2001-10-11 | Valmar Izdelava Strojev In Pre | Bottle for dispensing syrup for decorating ice cream has support into which its top fits, allowing it to be stored with dispensing spout downwards |
US6341718B1 (en) * | 1998-12-07 | 2002-01-29 | V.O.F. Pharmasept | Squeeze bottle for dispensing a liquid in a metered and substantially germ-free manner |
US6446844B1 (en) | 2001-12-18 | 2002-09-10 | Seaquist Closures Foreign, Inc. | Closure with internal flow control for a pressure openable valve in an extendable/retractable nozzle |
Family Cites Families (7)
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---|---|---|---|---|
US1504920A (en) * | 1923-06-22 | 1924-08-12 | Viegelmann Robert | Collapsible container |
US3726436A (en) * | 1971-04-14 | 1973-04-10 | Despain Flandro | Dispenser with flap valve |
IT1072495B (en) * | 1977-03-30 | 1985-04-10 | Deterchimica Snc | DISPOSABLE DISPENSER DISPENSER CONTAINER FOR SEMIFLUID PASTOUS PRODUCTS IN GENERAL AND FOR COSMETIC PRODUCTS IN PARTICULAR |
US5632420A (en) * | 1993-11-03 | 1997-05-27 | Zeller Plastik, Inc. | Dispensing package |
US5542585A (en) * | 1994-08-31 | 1996-08-06 | Polytop Corporation | Dispensing closure with pivotably mounted spout and means for limiting travel thereof |
US5865349A (en) * | 1997-08-25 | 1999-02-02 | Cancilla; Philip | Bottle with integrally coupled flap |
USH2027H1 (en) * | 2001-06-06 | 2002-06-04 | Seaquist Closures Foreign, Inc. | Flexible slit valve |
-
2002
- 2002-12-06 GB GBGB0228483.4A patent/GB0228483D0/en not_active Ceased
-
2003
- 2003-12-05 EP EP03780350A patent/EP1567419A1/en not_active Withdrawn
- 2003-12-05 RU RU2005121273/12A patent/RU2005121273A/en not_active Application Discontinuation
- 2003-12-05 AU AU2003288431A patent/AU2003288431A1/en not_active Abandoned
- 2003-12-05 WO PCT/GB2003/005314 patent/WO2004052734A1/en not_active Application Discontinuation
- 2003-12-05 CA CA002506437A patent/CA2506437A1/en not_active Abandoned
- 2003-12-05 US US10/532,126 patent/US20060016835A1/en not_active Abandoned
- 2003-12-05 PL PL03375571A patent/PL375571A1/en not_active IP Right Cessation
- 2003-12-05 NZ NZ539391A patent/NZ539391A/en unknown
-
2005
- 2005-04-13 ZA ZA200502974A patent/ZA200502974B/en unknown
Patent Citations (9)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3572590A (en) * | 1968-05-31 | 1971-03-30 | Afa Corp | Squeeze bottle atomizers and liquid dispensers |
DE7923294U1 (en) * | 1979-08-16 | 1980-01-03 | Pfaelzische Sprit Und Chem Fab | Dosing container |
GB2106480A (en) * | 1981-09-29 | 1983-04-13 | Shinko Chem | Valve and container for medical liquids |
US5439143A (en) | 1991-12-06 | 1995-08-08 | Liquid Molding Systems, Inc. | Dispensing valve for packaging |
US5954237A (en) | 1995-08-25 | 1999-09-21 | The Coca-Cola Company | Dispensing valve closure with inner seal |
GB2339757A (en) * | 1998-07-17 | 2000-02-09 | Unilever Plc | Dispensing containers |
US6341718B1 (en) * | 1998-12-07 | 2002-01-29 | V.O.F. Pharmasept | Squeeze bottle for dispensing a liquid in a metered and substantially germ-free manner |
DE10112741A1 (en) * | 2000-03-09 | 2001-10-11 | Valmar Izdelava Strojev In Pre | Bottle for dispensing syrup for decorating ice cream has support into which its top fits, allowing it to be stored with dispensing spout downwards |
US6446844B1 (en) | 2001-12-18 | 2002-09-10 | Seaquist Closures Foreign, Inc. | Closure with internal flow control for a pressure openable valve in an extendable/retractable nozzle |
Also Published As
Publication number | Publication date |
---|---|
US20060016835A1 (en) | 2006-01-26 |
PL375571A1 (en) | 2005-11-28 |
GB0228483D0 (en) | 2003-01-08 |
CA2506437A1 (en) | 2004-06-24 |
AU2003288431A1 (en) | 2004-06-30 |
ZA200502974B (en) | 2005-10-20 |
RU2005121273A (en) | 2006-01-20 |
NZ539391A (en) | 2006-11-30 |
EP1567419A1 (en) | 2005-08-31 |
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