WO2004050007A3 - Mammalian bt-42 proteins involved in the regulation of energy homeostasis - Google Patents

Mammalian bt-42 proteins involved in the regulation of energy homeostasis Download PDF

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Publication number
WO2004050007A3
WO2004050007A3 PCT/EP2003/013521 EP0313521W WO2004050007A3 WO 2004050007 A3 WO2004050007 A3 WO 2004050007A3 EP 0313521 W EP0313521 W EP 0313521W WO 2004050007 A3 WO2004050007 A3 WO 2004050007A3
Authority
WO
WIPO (PCT)
Prior art keywords
mammalian
regulation
energy homeostasis
proteins involved
diseases
Prior art date
Application number
PCT/EP2003/013521
Other languages
French (fr)
Other versions
WO2004050007A2 (en
Inventor
Kay Schreiter
Original Assignee
Develogen Ag
Kay Schreiter
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Develogen Ag, Kay Schreiter filed Critical Develogen Ag
Priority to AU2003293745A priority Critical patent/AU2003293745A1/en
Publication of WO2004050007A2 publication Critical patent/WO2004050007A2/en
Publication of WO2004050007A3 publication Critical patent/WO2004050007A3/en

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Classifications

    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K67/00—Rearing or breeding animals, not otherwise provided for; New or modified breeds of animals
    • A01K67/027—New or modified breeds of vertebrates
    • A01K67/0275—Genetically modified vertebrates, e.g. transgenic
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/1703—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • A61K38/1709—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/16—Hydrolases (3) acting on ester bonds (3.1)
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K2217/00—Genetically modified animals
    • A01K2217/05—Animals comprising random inserted nucleic acids (transgenic)
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K2227/00—Animals characterised by species
    • A01K2227/10—Mammal
    • A01K2227/105—Murine
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K2267/00—Animals characterised by purpose
    • A01K2267/03—Animal model, e.g. for test or diseases
    • A01K2267/035—Animal model for multifactorial diseases
    • A01K2267/0362—Animal model for lipid/glucose metabolism, e.g. obesity, type-2 diabetes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy

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  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Zoology (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Chemistry (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Wood Science & Technology (AREA)
  • Environmental Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Organic Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Marine Sciences & Fisheries (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • Animal Husbandry (AREA)
  • Biodiversity & Conservation Biology (AREA)
  • Molecular Biology (AREA)
  • General Engineering & Computer Science (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Immunology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Epidemiology (AREA)
  • Public Health (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

The present invention discloses BT-42 homologous proteins regulating the energy homeostasis and the metabolism of triglycerides, and polynucleotides, which identify and encode the proteins disclosed in this invention. The invention also relates to the use of these sequences in the diagnosis, study, prevention, and treatment of diseases and disorders, for example, but not limited to, metabolic disorders and diseases.
PCT/EP2003/013521 2002-11-29 2003-12-01 Mammalian bt-42 proteins involved in the regulation of energy homeostasis WO2004050007A2 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
AU2003293745A AU2003293745A1 (en) 2002-11-29 2003-12-01 Mammalian bt-42 proteins involved in the regulation of energy homeostasis

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP02026693.8 2002-11-29
EP02026693 2002-11-29

Publications (2)

Publication Number Publication Date
WO2004050007A2 WO2004050007A2 (en) 2004-06-17
WO2004050007A3 true WO2004050007A3 (en) 2005-07-07

Family

ID=32405685

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/EP2003/013521 WO2004050007A2 (en) 2002-11-29 2003-12-01 Mammalian bt-42 proteins involved in the regulation of energy homeostasis

Country Status (2)

Country Link
AU (1) AU2003293745A1 (en)
WO (1) WO2004050007A2 (en)

Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5874290A (en) * 1996-11-08 1999-02-23 Northwest Biotherapeutics, Llc Nucleotide and amino acid sequences of a D2-2 gene associated with brain tumors and methods based thereon
US5990294A (en) * 1996-11-08 1999-11-23 Northwest Biotherapeutics Llc Nucleotide and amino acid sequences of C4-2, a tumor suppressor gene, and methods of use thereof
WO2001096371A2 (en) * 2000-06-16 2001-12-20 Develogen Ag Adipose-related gene
WO2003010327A2 (en) * 2001-02-21 2003-02-06 Curagen Corporation Novel proteins and nucleic acids encoding same
WO2004066948A2 (en) * 2003-01-29 2004-08-12 Exelixis Inc. Mapcaxs as modifiers of the apc and axin pathways and methods of use

Patent Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5874290A (en) * 1996-11-08 1999-02-23 Northwest Biotherapeutics, Llc Nucleotide and amino acid sequences of a D2-2 gene associated with brain tumors and methods based thereon
US5990294A (en) * 1996-11-08 1999-11-23 Northwest Biotherapeutics Llc Nucleotide and amino acid sequences of C4-2, a tumor suppressor gene, and methods of use thereof
WO2001096371A2 (en) * 2000-06-16 2001-12-20 Develogen Ag Adipose-related gene
WO2003010327A2 (en) * 2001-02-21 2003-02-06 Curagen Corporation Novel proteins and nucleic acids encoding same
WO2004066948A2 (en) * 2003-01-29 2004-08-12 Exelixis Inc. Mapcaxs as modifiers of the apc and axin pathways and methods of use

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
DATABASE EMBL-EBI 1 July 1997 (1997-07-01), XP002325241, Database accession no. AB002375 *
DATABASE EMBL-EBI 16 October 2002 (2002-10-16), XP002325240, Database accession no. AF543190 *

Also Published As

Publication number Publication date
AU2003293745A8 (en) 2004-06-23
WO2004050007A2 (en) 2004-06-17
AU2003293745A1 (en) 2004-06-23

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