WO2004033472A8 - Method for producing monomer uronic acids, especially d- mannuronic acid and d-guluronic acid and derivatives thereof, and the use of the same as medicaments - Google Patents

Method for producing monomer uronic acids, especially d- mannuronic acid and d-guluronic acid and derivatives thereof, and the use of the same as medicaments

Info

Publication number
WO2004033472A8
WO2004033472A8 PCT/DE2003/003349 DE0303349W WO2004033472A8 WO 2004033472 A8 WO2004033472 A8 WO 2004033472A8 DE 0303349 W DE0303349 W DE 0303349W WO 2004033472 A8 WO2004033472 A8 WO 2004033472A8
Authority
WO
WIPO (PCT)
Prior art keywords
acid
derivatives
medicaments
uronic acids
same
Prior art date
Application number
PCT/DE2003/003349
Other languages
German (de)
French (fr)
Other versions
WO2004033472A1 (en
Inventor
Bernd Helmut Adam Rehm
Original Assignee
Univ Muenster Wilhelms
Bernd Helmut Adam Rehm
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from DE10247073A external-priority patent/DE10247073B4/en
Priority claimed from DE10253514A external-priority patent/DE10253514A1/en
Priority claimed from DE10261693A external-priority patent/DE10261693A1/en
Application filed by Univ Muenster Wilhelms, Bernd Helmut Adam Rehm filed Critical Univ Muenster Wilhelms
Priority to AU2003277820A priority Critical patent/AU2003277820A1/en
Publication of WO2004033472A1 publication Critical patent/WO2004033472A1/en
Publication of WO2004033472A8 publication Critical patent/WO2004033472A8/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H7/00—Compounds containing non-saccharide radicals linked to saccharide radicals by a carbon-to-carbon bond
    • C07H7/02—Acyclic radicals
    • C07H7/033—Uronic acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Immunology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Rheumatology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

The invention relates to a method for producing monomer uronic acids, especially mannuronic acid and guluronic acid, preferably from microbially produced polymannuronate or polyguluronate, and to the pharmacologically active derivatives thereof. The invention also relates to the use of said substances for producing an antiphlogistic pharmaceutical composition which can be used to treat arthritis.
PCT/DE2003/003349 2002-10-09 2003-10-08 Method for producing monomer uronic acids, especially d- mannuronic acid and d-guluronic acid and derivatives thereof, and the use of the same as medicaments WO2004033472A1 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
AU2003277820A AU2003277820A1 (en) 2002-10-09 2003-10-08 Method for producing monomer uronic acids, especially d- mannuronic acid and d-guluronic acid and derivatives thereof, and the use of the same as medicaments

Applications Claiming Priority (6)

Application Number Priority Date Filing Date Title
DE10247073.1 2002-10-09
DE10247073A DE10247073B4 (en) 2002-10-09 2002-10-09 Process for the preparation of monomeric uronic acids, in particular D-mannuronic acid and D-guluronic acid and their use as medicaments
DE10253514.0 2002-11-16
DE10253514A DE10253514A1 (en) 2002-11-16 2002-11-16 Production of new or known monomeric uronic acid compounds, useful e.g. as immunosuppressive or antiarthritic agents, by hydrolyzing bacterially produced polyuronic acid
DE10261693A DE10261693A1 (en) 2002-10-09 2002-12-30 Production of new or known monomeric uronic acid compounds, useful e.g. as immunosuppressive or antiarthritic agents, by hydrolyzing bacterially produced polyuronic acid
DE10261693.0 2002-12-30

Publications (2)

Publication Number Publication Date
WO2004033472A1 WO2004033472A1 (en) 2004-04-22
WO2004033472A8 true WO2004033472A8 (en) 2004-08-26

Family

ID=32096512

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/DE2003/003349 WO2004033472A1 (en) 2002-10-09 2003-10-08 Method for producing monomer uronic acids, especially d- mannuronic acid and d-guluronic acid and derivatives thereof, and the use of the same as medicaments

Country Status (2)

Country Link
AU (1) AU2003277820A1 (en)
WO (1) WO2004033472A1 (en)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN110151773A (en) * 2019-05-13 2019-08-23 深圳大学 Oligoguluronic Acids are preventing and treating the application in Tau albumen medicine

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1268954B1 (en) * 1994-03-11 1997-03-18 Fidia Advanced Biopolymers Srl PROCESS FOR THE PREPARATION OF HYALURONIC ACID BY MEANS OF ENZYMATIC SYNTHESIS AND RELATED PHARMACEUTICAL COMPOSITIONS
KR100501584B1 (en) * 2000-02-03 2005-07-18 (주)케이비피 Process for preparing low molecular polymannuronate, a novel use thereof as controller of serum lipids, and functional foods and health-aid foods comprising the same

Also Published As

Publication number Publication date
AU2003277820A1 (en) 2004-05-04
WO2004033472A1 (en) 2004-04-22

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