WO2004024100A1 - Ciments ionomeres de verre, poudre de verre associee et procedes de production correspondants - Google Patents

Ciments ionomeres de verre, poudre de verre associee et procedes de production correspondants Download PDF

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Publication number
WO2004024100A1
WO2004024100A1 PCT/SG2003/000216 SG0300216W WO2004024100A1 WO 2004024100 A1 WO2004024100 A1 WO 2004024100A1 SG 0300216 W SG0300216 W SG 0300216W WO 2004024100 A1 WO2004024100 A1 WO 2004024100A1
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WO
WIPO (PCT)
Prior art keywords
glass
cement
particles
spherical
glass powder
Prior art date
Application number
PCT/SG2003/000216
Other languages
English (en)
Inventor
U Jin Adrian Yap
Hong Ning Philip Cheang
Yanwei Gu
Original Assignee
National University Of Singapore
Nanyang Technological University
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by National University Of Singapore, Nanyang Technological University filed Critical National University Of Singapore
Priority to AU2003259019A priority Critical patent/AU2003259019A1/en
Publication of WO2004024100A1 publication Critical patent/WO2004024100A1/fr

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L24/00—Surgical adhesives or cements; Adhesives for colostomy devices
    • A61L24/04—Surgical adhesives or cements; Adhesives for colostomy devices containing macromolecular materials
    • A61L24/12—Ionomer cements, e.g. glass-ionomer cements
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K6/00—Preparations for dentistry
    • A61K6/30—Compositions for temporarily or permanently fixing teeth or palates, e.g. primers for dental adhesives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K6/00—Preparations for dentistry
    • A61K6/80—Preparations for artificial teeth, for filling teeth or for capping teeth
    • A61K6/884—Preparations for artificial teeth, for filling teeth or for capping teeth comprising natural or synthetic resins
    • A61K6/887—Compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds
    • A61K6/889—Polycarboxylate cements; Glass ionomer cements
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L24/00—Surgical adhesives or cements; Adhesives for colostomy devices
    • A61L24/001—Use of materials characterised by their function or physical properties
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B82—NANOTECHNOLOGY
    • B82Y—SPECIFIC USES OR APPLICATIONS OF NANOSTRUCTURES; MEASUREMENT OR ANALYSIS OF NANOSTRUCTURES; MANUFACTURE OR TREATMENT OF NANOSTRUCTURES
    • B82Y30/00—Nanotechnology for materials or surface science, e.g. nanocomposites
    • C—CHEMISTRY; METALLURGY
    • C03—GLASS; MINERAL OR SLAG WOOL
    • C03B—MANUFACTURE, SHAPING, OR SUPPLEMENTARY PROCESSES
    • C03B19/00—Other methods of shaping glass
    • C03B19/10—Forming beads
    • C03B19/1005—Forming solid beads
    • C03B19/102—Forming solid beads by blowing a gas onto a stream of molten glass or onto particulate materials, e.g. pulverising
    • C—CHEMISTRY; METALLURGY
    • C03—GLASS; MINERAL OR SLAG WOOL
    • C03B—MANUFACTURE, SHAPING, OR SUPPLEMENTARY PROCESSES
    • C03B19/00—Other methods of shaping glass
    • C03B19/10—Forming beads
    • C03B19/1005—Forming solid beads
    • C03B19/1045—Forming solid beads by bringing hot glass in contact with a liquid, e.g. shattering
    • C—CHEMISTRY; METALLURGY
    • C03—GLASS; MINERAL OR SLAG WOOL
    • C03C—CHEMICAL COMPOSITION OF GLASSES, GLAZES OR VITREOUS ENAMELS; SURFACE TREATMENT OF GLASS; SURFACE TREATMENT OF FIBRES OR FILAMENTS MADE FROM GLASS, MINERALS OR SLAGS; JOINING GLASS TO GLASS OR OTHER MATERIALS
    • C03C12/00—Powdered glass; Bead compositions

Definitions

  • the present invention relates generally to dentistry and biomedicine, and more particularly to glass ionomer cements for use in dentistry and other biomedical applications.
  • Glass ionomer cements typically composed of an aluminosilicate glass powder (such as calcium fluoro-aluminosilicate) and an aqueous solution of an acrylic acid homo or co-polymer (polyectrolyte), are clinically attractive dental materials.
  • aluminosilicate glass powder such as calcium fluoro-aluminosilicate
  • an acrylic acid homo or co-polymer polyectrolyte
  • Resin-modified glass ionomer materials a status report for the American Journal of Dentistry. Am J Dent; 8: 59-67 and Hassan MA, Watson T.F. (1998).
  • Conventional glass ionomer cements as posterior restorations a status report for the American Journal of Dentistry. Am J Dent; 11 : 36-45.
  • HVGICs have also been reported to be stronger and more wear resistant than some other metal reinforced GICs.
  • One major clinical problem encountered with HVGICs is the inability to hand mix HVGICs at the manufacturer's recommended P:L ratio. This results in material wastage and less than optimal physical properties.
  • improved GICs exhibiting one or more of (a) improved mixing characteristics; (b) improved flow characteristics; (c) increase powder : liquid ratios; and (d) improve physical properties are desirable.
  • exemplary GICs are formed of generally spherical glass particles.
  • spherical particles allow for higher P:L ratios, better integration/packing and have a lower tendency to act as foci of stress concentrations.
  • a dental cement in which a substantial portion of glass particles in the cement are generally spherical glass particles.
  • a method of forming a glass ionomer cement includes processing angular glass powder to form spherical glass powder; and mixing the spherical glass powder with an aqueous solution of an acidic polymer to form the glass ionomer cement.
  • a method of forming spherical glass powder for use in the formation of dental cements including processing angular calcium fluoro- aluminosilicate glass powder to form the spherical glass powder.
  • generally spherical fluoro-aluminosilicate glass powders are used in the formation of dental cements.
  • generally spherical fluoro-aluminosilicate glass powders are used as a substantial portion of glass particles in dental cement.
  • FIG. 1 is a scanning electron microscope image of conventional glass powders used in GICs
  • FIG. 2 is a schematic process diagram illustrating a glass powder production process, exemplary of an embodiment of the present invention
  • FIG. 3 is a scanning electron microscope image of glass powders for use in GICs formed in accordance of with the process of FIG. 2;
  • FIG. 4 is a process diagram illustrating a further glass powder production process, exemplary of an embodiment of the present invention.
  • FIGS. 5A and 5B are scanning electron microscope images of spherical glass powders formed in accordance with the process of FIG. 4, exemplary of an embodiment of the present invention
  • FIG. 6 is a scanning electron microscope image of a fractured surface HVGIC formed of spherical glass powders, exemplary of embodiments of the present invention.
  • FIGS. 7A and 7B are graphs illustrating particle size distribution of spherical glass powder particles, formed with the processes of FIGS. 2 and 4, respectively.
  • GICs are formed using generally spherical glass powders.
  • Angular glass powders as for example depicted in the scanning electron microscope image of FIG. 1 , may be converted to spherical glass powders in a variety of ways understood by those of ordinary skill.
  • angular powders could be converted to spherical powders by several processes including ball milling, liquid formation and thermal processing.
  • Process I flame spraying
  • Process II radio frequency
  • FIG. 2 is a process flow diagram, illustrating example Process I for forming spherical glass powders using flame spraying, exemplary of an embodiment of the present invention.
  • conventional angular glass particles 12 are transported to flame sprayer 16 by way of closed-loop motorized hopper 14.
  • Flame sprayer 16 provides an open flame 26, and may be fuelled by a mixture of acetylene and oxygen. Of course, alternative fuel sources are possible.
  • the burning fuel melts the glass to produce a fine spray 18 of glass particles.
  • An interior flow 20 of compressed air within the combustion flame accelerates the spray 18 particles from flame gun 16 dispersing them into a basin 22 of distilled water, acting as a coolant for spray 18.
  • Resulting spherical glass particles are collected from basin 22 from which they are collected and transported to a dryer 24.
  • Example spherical glasses (FS glass) so produced are shown in the scanning electron microscope image of FIG. 3.
  • FIG. 4 illustrates an alternative example Process II: angular glass powders 42 are sprayed using a 35kW inductively coupled RF plasma spheroidized installation 30 including torch 32 and atomizing probe 34.
  • Atomizing gas as such as argon/oxygen is introduced into atomizing chamber 40, by way of conduit 38. Within chamber 40 the gas is ionized producing a flow of plasma.
  • Angular powders are fed into the flow of plasma via a solid powder feeder 36.
  • Spraying parameters for example Process II are listed in Table 2.
  • the powders are melted and vaporized by installation 30 and resolidified prior separation into different particle size range.
  • Spheroidization may be carried out at various plate powers ranging from 6.8 to 18 kW.
  • heat treatment in carbolite chamber furnace 44 controls working time and setting time of spherical glass powders.
  • the glass powders are maintained in the range of 500 to 1000°C in a furnace 42 allowing the spherical powders to cool slowly.
  • Example spherical glasses produced by Process II are shown in the scanning electron microscope images of FIGS. 5A and 5B. As will become apparent, particle sizes can range from the nanometer scale to 40 ⁇ m or greater depending on the plate power.
  • glass ionomer cements may be formed by adding acidic polymers to the spherical glass particles formed in accordance with the processes depicted in FIGS. 2 and 4. As will become apparent, spherical glass particles may be mixed with conventional glass particles to form glass ionomer cements.
  • Experimental HVGIC materials may similarly be made by reacting spherical and mixed spherical and angular glass powders with polyalkenoic acid using high-speed capsulated mixing technology at a P:L ratio (0.362 g:1.0 g).
  • P:L ratio 0.362 g:1.0 g
  • ratios ranging from 1.5g: 1.0g to 7.0g: 1.0g may be possible.
  • Size distribution of spherical particles formed in accordance with Process I and Process II are illustrated in FIGS. 7A and 7B, respectively.
  • spherical glass particles formed in accordance with Process I have particle size (i.e. mean diameter) ranges of between 5 and 50 ⁇ m and mean particle size 20.9 ⁇ m.
  • Group I - spherical glass from example Process I i.e. spherical FS glass -particle size range of 5 to 50 ⁇ m; mean particle size 20.9 ⁇ m
  • Group II - spherical glass from Process II i.e. i.e. spherical RF glass - particle size range of 0.5 to 40 ⁇ m; mean particle size 9.0 ⁇ m
  • Group III 50% angular (particle size range of 0.3 to 50 ⁇ m; mean particle size 7.9 ⁇ m) and 50% spherical RF glass
  • Group IV - 25% angular and 75% spherical RF glass.
  • spherical glass particles could be incorporated in a large range of GIC products, ranging from luting cements to filling materials, including conventional GIC cements and resin enhanced GIC cements.
  • Spherical glass powders can also be compounded with fibrous glass powders, as for example disclosed in US Patent No. 6,355,585, metal and other fillers to improve handling and other properties.
  • cements formed with spherical glass particles may have superior mixing characteristics, increased P:L ratios and improved physio-mechanical properties.
  • the nano-sized spherical particles may increase setting time and lower film thickness of luting cements.
  • spherical particles in the formation of glass ionomer cements may provide numerous benefits.
  • suitable spherical particles can be made from several other techniques known to those of ordinary skill.
  • spherical glass particles can also be used to form other dental cements containing materials like compomers and giomers.

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Materials Engineering (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Organic Chemistry (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Nanotechnology (AREA)
  • Manufacturing & Machinery (AREA)
  • Surgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Geochemistry & Mineralogy (AREA)
  • Plastic & Reconstructive Surgery (AREA)
  • Physics & Mathematics (AREA)
  • Composite Materials (AREA)
  • Condensed Matter Physics & Semiconductors (AREA)
  • General Physics & Mathematics (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Dental Preparations (AREA)

Abstract

La présente invention se rapporte à des ciments ionomères de verre, destinés à être utilisés en tant que matériaux dentaires, qui sont constitués de particules de verre globalement sphériques. Des procédés de formation de tels ciments ionomères de verre et de telles particules de verre sont également présentés. De manière avantageuse, les particules sphériques peuvent assurer des rapports poudre/liquide plus élevés, une meilleure intégration et/ou un meilleur tassement et ont une moindre tendance à se transformer en foyers des concentrations de contraintes.
PCT/SG2003/000216 2002-09-10 2003-09-10 Ciments ionomeres de verre, poudre de verre associee et procedes de production correspondants WO2004024100A1 (fr)

Priority Applications (1)

Application Number Priority Date Filing Date Title
AU2003259019A AU2003259019A1 (en) 2002-09-10 2003-09-10 Glass ionomer cements, glass powder therefor, and methods of manufacture

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US40921102P 2002-09-10 2002-09-10
US60/409,211 2002-09-10

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Publication Number Publication Date
WO2004024100A1 true WO2004024100A1 (fr) 2004-03-25

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Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2005115936A2 (fr) * 2004-05-29 2005-12-08 Schott Ag Nanopoudre de verre et son utilisation, notamment poudre de verre a composants multiples, de grandeur particulaire moyenne inferieure a 1 $g(m)m

Citations (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5051453A (en) * 1988-02-08 1991-09-24 Tokuyama Soda Kabushiki Kaisha Cement composition
US5084491A (en) * 1989-03-16 1992-01-28 The Ohio University Reinforcing glass ionomer dental filling material with stainless steel, or metals thereof
DE4108634A1 (de) * 1991-03-16 1992-09-17 Bayer Ag Dentalwerkstoffe
AU640041B2 (en) * 1990-09-14 1993-08-12 Ivoclar Ag Polymerizable dental material
US5350782A (en) * 1991-09-06 1994-09-27 Kanebo, Ltd. Dental filling composition
DE19832965A1 (de) * 1998-07-22 2000-02-03 Fraunhofer Ges Forschung Sphärische Ionomerpartikel und deren Herstellung
WO2000012437A1 (fr) * 1998-08-27 2000-03-09 Superior Micropowders Llc Poudres de verre, procedes de production de poudres de verre et dispositifs façonnes a partir de ceux-ci
JP2001164073A (ja) * 1999-12-08 2001-06-19 Nippon Electric Glass Co Ltd 生体活性セメント組成物
EP1156021A1 (fr) * 2000-05-19 2001-11-21 Asahi Glass Co., Ltd. Microsphères creuses en verre et leur procédé de production
US6326417B1 (en) * 1999-10-21 2001-12-04 Jeneric/Pentron Incorporated Anti-microbial dental compositions and method

Patent Citations (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5051453A (en) * 1988-02-08 1991-09-24 Tokuyama Soda Kabushiki Kaisha Cement composition
US5084491A (en) * 1989-03-16 1992-01-28 The Ohio University Reinforcing glass ionomer dental filling material with stainless steel, or metals thereof
US5189077A (en) * 1989-03-16 1993-02-23 The Ohio State University Reinforcing glass ionomer dental filling material with titanium stainless steel, or metals thereof
US5189077B1 (en) * 1989-03-16 1996-07-23 British Tech Group Usa Reinforcing glass ionomer dental filling material with titatium stainless steel or metals thereof
AU640041B2 (en) * 1990-09-14 1993-08-12 Ivoclar Ag Polymerizable dental material
DE4108634A1 (de) * 1991-03-16 1992-09-17 Bayer Ag Dentalwerkstoffe
US5350782A (en) * 1991-09-06 1994-09-27 Kanebo, Ltd. Dental filling composition
DE19832965A1 (de) * 1998-07-22 2000-02-03 Fraunhofer Ges Forschung Sphärische Ionomerpartikel und deren Herstellung
WO2000012437A1 (fr) * 1998-08-27 2000-03-09 Superior Micropowders Llc Poudres de verre, procedes de production de poudres de verre et dispositifs façonnes a partir de ceux-ci
US6326417B1 (en) * 1999-10-21 2001-12-04 Jeneric/Pentron Incorporated Anti-microbial dental compositions and method
JP2001164073A (ja) * 1999-12-08 2001-06-19 Nippon Electric Glass Co Ltd 生体活性セメント組成物
EP1156021A1 (fr) * 2000-05-19 2001-11-21 Asahi Glass Co., Ltd. Microsphères creuses en verre et leur procédé de production

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* Cited by examiner, † Cited by third party
Title
DATABASE WPI Week 199239, Derwent World Patents Index; Class P32, AN 1992-317195 *
DATABASE WPI Week 200156, Derwent World Patents Index; Class A96, AN 2001-505905 *

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2005115936A2 (fr) * 2004-05-29 2005-12-08 Schott Ag Nanopoudre de verre et son utilisation, notamment poudre de verre a composants multiples, de grandeur particulaire moyenne inferieure a 1 $g(m)m
WO2005115936A3 (fr) * 2004-05-29 2006-02-16 Schott Ag Nanopoudre de verre et son utilisation, notamment poudre de verre a composants multiples, de grandeur particulaire moyenne inferieure a 1 $g(m)m
EP2189426A1 (fr) * 2004-05-29 2010-05-26 Schott AG Procédé pour préparer de nanopoudre de verre
US7816292B2 (en) 2004-05-29 2010-10-19 Schott Ag Nano glass powder and use thereof, in particular multicomponent glass powder with a mean particle size of less than 1 μm

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AU2003259019A8 (en) 2004-04-30
AU2003259019A1 (en) 2004-04-30

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