WO2004024058A3 - Molecules a activite antitumorale, et procede de synthese chimique - Google Patents

Molecules a activite antitumorale, et procede de synthese chimique Download PDF

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Publication number
WO2004024058A3
WO2004024058A3 PCT/BR2003/000128 BR0300128W WO2004024058A3 WO 2004024058 A3 WO2004024058 A3 WO 2004024058A3 BR 0300128 W BR0300128 W BR 0300128W WO 2004024058 A3 WO2004024058 A3 WO 2004024058A3
Authority
WO
WIPO (PCT)
Prior art keywords
antitumor activity
molecules
chemical synthesis
acridine
synthesis
Prior art date
Application number
PCT/BR2003/000128
Other languages
English (en)
Other versions
WO2004024058A2 (fr
Inventor
Rocha Pitta Ivan Da
De Lima Maria Do Carmo Alves
Galdino Suely Lins
Jacques Barbe
Original Assignee
Conselho Nacional Cnpq
Rocha Pitta Ivan Da
De Lima Maria Do Carmo Alves
Galdino Suely Lins
Jacques Barbe
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Conselho Nacional Cnpq, Rocha Pitta Ivan Da, De Lima Maria Do Carmo Alves, Galdino Suely Lins, Jacques Barbe filed Critical Conselho Nacional Cnpq
Publication of WO2004024058A2 publication Critical patent/WO2004024058A2/fr
Publication of WO2004024058A3 publication Critical patent/WO2004024058A3/fr

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents

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  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Medicines Containing Plant Substances (AREA)

Abstract

L'invention porte sur la synthèse et la structure de nouveaux composés d'acridine-thiazolidine-thiazacridine et d'acridine-imidaziolidine-imidazacridine à activité antitumorale, et sur leur utilisation thérapeutique comme agents anticancéreux.
PCT/BR2003/000128 2002-09-10 2003-09-09 Molecules a activite antitumorale, et procede de synthese chimique WO2004024058A2 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
BRPI0203747-5 2002-09-10
BR0203747-5A BR0203747A (pt) 2002-09-10 2002-09-10 Moléculas com atividade antitumoral e processo para a sua obtenção

Publications (2)

Publication Number Publication Date
WO2004024058A2 WO2004024058A2 (fr) 2004-03-25
WO2004024058A3 true WO2004024058A3 (fr) 2004-05-27

Family

ID=31983570

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/BR2003/000128 WO2004024058A2 (fr) 2002-09-10 2003-09-09 Molecules a activite antitumorale, et procede de synthese chimique

Country Status (2)

Country Link
BR (1) BR0203747A (fr)
WO (1) WO2004024058A2 (fr)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ITMI20042475A1 (it) * 2004-12-23 2005-03-23 Cell Therapeutics Europe Srl Uso di derivati tiazolidinonici come agenti terapeutici
EP1959958A4 (fr) * 2005-11-14 2010-07-14 Univ Southern California Petites molecules de liaison a une integrine
BRPI0601827A (pt) * 2006-03-24 2007-11-27 Univ Fed Pernambuco moléculas com atividade antitumoral
BRPI1101273B1 (pt) * 2011-03-10 2022-07-19 Universidade Federal De Pernambuco Moléculas imidazolidínicas e tiazoldínicas com atividades anti-t.cruzi
WO2013053034A2 (fr) * 2011-10-10 2013-04-18 Universidade Federal De Pernambuco - Ufpe Thiazacridines utilisées dans la thérapie anticancéreuse
CN107954938A (zh) * 2017-12-01 2018-04-24 苏州艾缇克药物化学有限公司 一种1h-咪唑-4-甲酸的合成方法

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
SILVA, T.G. ET AL.: "Synthesis and structural elucidation of new benzylidene imidazolidines and acridinylidene thiazolidines", HETEROCYCL. COMMUN., vol. 7, no. 6, 2001, pages 523 - 528, XP002975509 *

Also Published As

Publication number Publication date
WO2004024058A2 (fr) 2004-03-25
BR0203747A (pt) 2004-05-25

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